Research State University

SAMMY ENI ENI

. Apt *** . Knoxville TN ***** . 423-***-**** . *********@*****.***

*** ******* **.

OBJECTIVE:

A full-time position in chemical, organic, analytical, or pharmaceutical research and or academic

setting that utilizes experiences in design, synthesis, training, tutoring and application in

medicinal, organic, analytical, and inorganic chemistry.

HIGHLIGHTS:

• Designed, synthesized, and characterized up to six unrelated lipid probes from

scratch.

• Extensive experience in protein cell extracts cultivation and labelling.

• Demonstrated ability in monitoring organic and inorganic reactions for biological

use.

• Taught undergraduate analytical, organic, and inorganic research labs for 7 years.

• Created, proctored, graded, and instructed undergraduate lab exams.

• Worked with instruments like GC, HPLC, NMR, MALDI MS, voyager MS, cell

imaging, cell culture, gel electrophoresis, fluorescent imaging, protein cross-

linking and purification, microaaray studies etc.

• Supervised and mentored graduate students, teaching assistants and students in

research.

• Earned “Top organic synthesis and teaching awards” in my departments of work.

• Comprehensively presented research results in conferences locally in the US and

abroad on invitation.

• Maintain great laboratory records of experimental results and findings.

• Laboratory safety officer and enforcer.

• Performing wet analysis on analytes using approved procedures.

• Proficient in new homogeneous and heterogeneous catalytic synthetic methodology

development and optimization with application of green chemistry using analytical

methods like GCMS (gas chromatography mass spectrometry) and ESIMS (Electrospray

ionisation mass spectrometry)

• Strong background in multi-step small molecule synthesis and characterization using

current organic synthesis methods with the application of spectroscopic analytical

methods like NMR and IR.

• Experienced at gram scale solid phase ligand/catalyst synthesis and application to

catalysis using FDA and EMA regulatory requirements for investigational products.

• Synthesis and characterization of air-sensitive inorganic and organometallic catalysts

using glovebox, Schlenk and other air-free techniques • Application of metal-catalyzed

reactions in efficient synthesis of organic small molecules.

• Good at HPLC (high performance liquid chromatography) method development for

separation of small molecules and peptide.

• Experienced at in-situ monitoring of complex reaction kinetics for reaction mechanism

elucidation with the application of reaction progress kinetic analysis using ReactIR. Also

adept at application of in-situ IR for detection of reaction intermediates.

• Excellent written, communication and interpersonal skills gained over several years as a

teaching assistant.

• Extensive experience in teaching (organic and analytical chemistry) and mentoring

undergraduate students.

• Supervised and mentored graduate students, teaching assistants and students in research.

• Perform complex calculations and communicating complex data

comprehensively.

• Industrial experience in an oil refinery (Limbe, Cameroon).

• Excellent oral, multi-lingual, and written communication skills.

EDUCATION:

• Ph.D in organic/medicinal chemistry, University of Tennessee, Knoxville, June

2015(Expected). Thesis title: “Design, Synthesis, and Application of Lipid Probes

for Proteomic Characterization of Protein Binding Partners”. GPA 3.67/4

• MS in inorganic chemistry, East Tennessee State University, Johnson city,

December 2009. Thesis title: “Determination of the Activation Parameters of

Reaction Between [Fe(CN6]-4 and K[Co(HEDTA)NO2]”. GPA 3.92/4

• BS in chemistry (summa cum laude), University of Buea, Cameroon, June 2007.

Thesis title: ” Isolation of Bioactive metabolites from cymbopogon citratus.”

HONORS:

• Organic Chemistry travel award (2015)

• Carolyn Vogel Chemistry Scholarship (2013-2014)

• Howard Advantage Student (2012), Phi Beta Kappa

• ACS Organic Chemist award (2010)

• Best Teaching Assistant award (2009)

• Outstanding Volunteering award (2008) Big Brothers Big Sisters

• President’s Best Graduating student award (2006), By Paul Biya President of the

Republic of Cameroon.

RESEARCH, TEACHING, AND INDUSTRIAL EXPERIENCE:

• University of Tennessee Knoxville, TN Aug 2010-

present

Advisers: Dr. Smith Laureta

o Designing and synthesis of a total of six lipid probes through a multi-step

scheme.

o Developing methodology for protein-binding interaction using synthetic

lipid probes.

o Characterizing the proteomic binding of proteins in cancer cell extracts as

they cross-link to lipid probes using tags (photoaffinity tags and azide

tags).

o Instructing organic and inorganic laboratory sections through multi-step

syntheses of compounds. Proctoring and grading exercises.

o Worked with instruments like GC, HPLC, NMR, MALDI MS, voyager

MS, cell imaging, cell culture, gel electrophoresis, fluorescent

imaging, protein cross-linking and purification, microaaray studies etc.

o Taught undergraduate analytical, organic, and inorganic research labs for 5

years.

o Created, proctored, graded, and instructed undergraduate lab exams.

o Organic Chemistry Laboratory Technician

o Graduate student ambassador and mentor.

• East Tennessee State University Johnson City, TN Jan 2008-Dec

2009

Adviser: Dr. Jeffrey G. Wardeska

o Monitoring the kinetics of the oxidation of [Fe(CN)6]-4 by

[Co(HEDTA)NO2] at various absorbant temperatures.

o Collecting and plotting data to use in devising the mechanism of

action and the activation parameters of the reaction between

[Fe(CN)6]-4 and K[Co(HEDTA)NO2] .

o Obtaining the activation parameters, energy of activation (Ea),

entropy of activation (ΔS ), and enthalpy of activation (ΔH ) for

the reaction.

o Taught undergraduate analytical, organic, and inorganic research

labs for 2 years.

o Created, proctored, graded, and instructed undergraduate lab

exams.

o Supervising and assisting students with multi-step syntheses of

compounds designed to teach organic laboratory techniques.

• National Oil Refinery Limbe, Cameroon, July 2006-

Dec Adviser: Dr. Oscar Ndoh

o Developing small-scale analysis of crude natural gas from oil wells

after cracking.

o Establishing a small sized, cost effective conversion process inside

a conventional, mass-produced engine.

o Small-scale production of methanol

o Assigning crew weekly tasks and duties.

IMMIGRATION/ US WORK STATUS

• Legal US permanent resident with green card.

LANGUAGES

• English

• French

• Pidgin

• Oroko

AFFILIATIONS

• Member, American Chemical Society.

• President, African Student Association, UT Chapter.

• Graduate student ambassador UTK

• Member, Gamma Beta Phi.

• Volunteer, Big Brothers Big Sisters Knoxville.

• Committed husband and father.

PUBLICATIONS AND PRESENTATIONS

• “Design and Application of Lipid Probes for Proteomic Characterization of

Protein Binding Partners”. Sammy Eni Eni. 249th National ACS Meeting,

Denver, Colorado, March 22-26, 2015.

• ”Modular Synthesis of Diacylglycerol Analogs Bearing Photoaffinity Tags For

Labelling Mammalian Diacylglycerol Kinase”. Sammy Eni Eni, Rowland Meng

and Michael D. Best. Bentham Science Publishers, 2015,24 (15), 83-85

• “Background on Lipid Metabolism and Involvement in Disease”. Sammy Eni

Eni, Kathrin Tscherch, Michael D. Best. HPTL Symposium, University of

Hamburg, Lyon, France. June 7-9th 2014.

• ”Synthesis, Analysis and Application of Phosphatidic Acid Probes for

Labeling and Proteomic Characterization of Protein

Binding Partners” Sammy Eni Eni. Drug Delivery Chemistry symposium San

Diego, 23 – 25th April 2010.

• “Determination of the Activation Parameters of Reaction Between

[Fe(CN6]-4 and K[Co(HEDTA)NO2]”. Sammy Eni Eni. Godon

Inorganic Research Conference, Biddeford, ME, June 20-25th 2010.

• Eni Eni, Sammy, "Determination of the Activation Parameters of Reaction

Between [Fe(CN6]-4 and K[Co(HEDTA)NO2]." (2009). Electronic Theses and

Dissertations. Paper 1798. http://dc.etsu.edu/etd/1798

REVIEWER & TRANSLATOR

• African Natural Resources Center (ANRC).

RECOMMENDATION

• Prof. Jeffrey G. Wardeska (*************@*****.***) 708-***-**** ETSU,

Johnson City TN

• Prof. Zi-Ling (Ben) Xue (***@***.****.***.***) 865-***-**** UTK Knoxville

TN

• Prof. Laureta Smith (******@***.****.***.***) 865-***-**** UTK Knoxville

TN

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