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Process University

Location:
New York, NY
Posted:
December 01, 2014

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Resume:

Yanqing Pan

(Green Card I*** EAD card holder)

*** ******* ******, ******, **, 08817

Phone: 732-***-****

Email: **************@*****.***

Qualification Summary

Proficiency with HPLC, NMR, IR, MS, GC, and other analytical methods (LOD and KF),

over 6 years of experience in organic compounds purification and characterizations.

2+ years of pharmaceutical industry experience in chemical process development and

optimization, extensive knowledge about process safety, robustness, and regulation.

6+ years of Organic Synthesis experience, including multi-step synthesis route design

and scouting, reaction troubleshooting.

Excellent communicating skills, including preparing technical report and oral presentation.

Highly efficient team player under collaborative environment; Well-developed time

management skills with the ability to multi task.

Excellent computer skills including Microsoft Word and excel.

Work Experience

Sr. Research Associate I R&D, Gilead Sciences, Alberta ULC 3/2012-6/2013

Visiting Researcher, Danishefsky Lab, Columbia University 12/2011-3/2012

Research Associate R&D, Gilead Sciences, Alberta ULC 10/2008-11/2009

Research Summary

Gilead Sciences, Alberta ULC. 10/2008-11/2009, 3/2012-6/2013

Process Developments for HCV NS5B and NRT Inhibitors, including Sovaldi.

Developed a Ring-Closing Metathesis process for a NS5B inhibitor.

Optimized a C-Glycosylation process for a nucleoside reverse transcriptase inhibitor.

Optimized a phosphorylation process for nucleoside reverse transcriptase inhibitors.

Danishefsky Lab, Columbia University 12/20011-3/2012

Total synthesis of Maoecrystal V program

Resume Yanqing Pan

Department of Chemistry, University of Alberta, Canada 09/2005-09/2008

Polyacetylene Glycosides and Thioglycosides: Chemical Synthesis and Bioactivity

Synthesized polyacetylene alcohols using Cadiot-Chodkiewicz coupling and FBW

(Fritsch-Buttenberg-Wiechell) Rearrangement.

Optimized glycosylation using various glycosylation methods to synthesize

polyacetylene glycosides and thioglycosides.

Carried bioactivity tests of polyacetylene glycosides and thioglycosides, including anti-

bacterial and anti-cancer activity. (SAR study)

Department of Chemistry, Beijing Normal University, China 09/2001-06/2004

Total Synthesis of Gingerols and their Analogues

Designed and Optimized Mukaiyama Aldol reaction and applied it to the total

synthesis of Gingerols and their analogues.

Education

Master of Science in Organic Chemistry, University of Alberta, Edmonton, Canada, 2009

Supervisors: Professor Todd L. Lowary and Professor Rik R. Tykwinski

Master of Science in Organic Chemistry, Beijing Normal University, Beijing, China, 2004

Supervisor: Professor He Li

Bachelor of Science in Chemistry, Beijing Normal University, Beijing, China, 2001

Posters

Synthesis of Polyacetylene Glycosides and Thioglycosides

Y. Pan, T. L. Lowary, R. R. Tykwinski, Canadian Chemistry Conference and Exhibition,

Edmonton, Alberta, May 2008.

Synthesis of Polyacetylene Glycosides and Thioglycosides

Y. Pan, T. L. Lowary, R. R. Tykwinski, National Carbohydrate Symposium, Lake Louse,

Alberta, May 2007.

Publications

1. Pan, Yanqing; Lowary, Todd L.; Tykwinski, Rik R. Naturally occurring and synthetic

polyyne glycosides, Canadian Journal of Chemistry, 2009, 87, 1565-1582.

2. Y. Pan, W. Li, H. Li. Synthesis of Analogues of Gingerol by using Bismuth Chloride,

Journal of Beijing Normal University (Natural Science) 2004, 40, 92-96.

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Resume Yanqing Pan

3. Y. Pan, W. Li, H. Li. Synthesis of Analogues of Gingerol by using Bismuth Chloride,

Journal of Beijing Normal University (Natural Science) 2002, 38, 230-233.

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