Yanqing Pan
(Green Card I*** EAD card holder)
*** ******* ******, ******, **, 08817
Phone: 732-***-****
Email: **************@*****.***
Qualification Summary
Proficiency with HPLC, NMR, IR, MS, GC, and other analytical methods (LOD and KF),
•
over 6 years of experience in organic compounds purification and characterizations.
2+ years of pharmaceutical industry experience in chemical process development and
•
optimization, extensive knowledge about process safety, robustness, and regulation.
6+ years of Organic Synthesis experience, including multi-step synthesis route design
•
and scouting, reaction troubleshooting.
Excellent communicating skills, including preparing technical report and oral presentation.
•
Highly efficient team player under collaborative environment; Well-developed time
•
management skills with the ability to multi task.
Excellent computer skills including Microsoft Word and excel.
•
Work Experience
Sr. Research Associate I R&D, Gilead Sciences, Alberta ULC 3/2012-6/2013
•
Visiting Researcher, Danishefsky Lab, Columbia University 12/2011-3/2012
•
Research Associate R&D, Gilead Sciences, Alberta ULC 10/2008-11/2009
•
Research Summary
Gilead Sciences, Alberta ULC. 10/2008-11/2009, 3/2012-6/2013
Process Developments for HCV NS5B and NRT Inhibitors, including Sovaldi.
Developed a Ring-Closing Metathesis process for a NS5B inhibitor.
•
Optimized a C-Glycosylation process for a nucleoside reverse transcriptase inhibitor.
•
Optimized a phosphorylation process for nucleoside reverse transcriptase inhibitors.
•
Danishefsky Lab, Columbia University 12/20011-3/2012
Total synthesis of Maoecrystal V program
Resume Yanqing Pan
Department of Chemistry, University of Alberta, Canada 09/2005-09/2008
Polyacetylene Glycosides and Thioglycosides: Chemical Synthesis and Bioactivity
Synthesized polyacetylene alcohols using Cadiot-Chodkiewicz coupling and FBW
•
(Fritsch-Buttenberg-Wiechell) Rearrangement.
Optimized glycosylation using various glycosylation methods to synthesize
•
polyacetylene glycosides and thioglycosides.
Carried bioactivity tests of polyacetylene glycosides and thioglycosides, including anti-
•
bacterial and anti-cancer activity. (SAR study)
Department of Chemistry, Beijing Normal University, China 09/2001-06/2004
Total Synthesis of Gingerols and their Analogues
Designed and Optimized Mukaiyama Aldol reaction and applied it to the total
•
synthesis of Gingerols and their analogues.
Education
Master of Science in Organic Chemistry, University of Alberta, Edmonton, Canada, 2009
Supervisors: Professor Todd L. Lowary and Professor Rik R. Tykwinski
Master of Science in Organic Chemistry, Beijing Normal University, Beijing, China, 2004
Supervisor: Professor He Li
Bachelor of Science in Chemistry, Beijing Normal University, Beijing, China, 2001
Posters
Synthesis of Polyacetylene Glycosides and Thioglycosides
Y. Pan, T. L. Lowary, R. R. Tykwinski, Canadian Chemistry Conference and Exhibition,
Edmonton, Alberta, May 2008.
Synthesis of Polyacetylene Glycosides and Thioglycosides
Y. Pan, T. L. Lowary, R. R. Tykwinski, National Carbohydrate Symposium, Lake Louse,
Alberta, May 2007.
Publications
1. Pan, Yanqing; Lowary, Todd L.; Tykwinski, Rik R. Naturally occurring and synthetic
polyyne glycosides, Canadian Journal of Chemistry, 2009, 87, 1565-1582.
2. Y. Pan, W. Li, H. Li. Synthesis of Analogues of Gingerol by using Bismuth Chloride,
Journal of Beijing Normal University (Natural Science) 2004, 40, 92-96.
2
Resume Yanqing Pan
3. Y. Pan, W. Li, H. Li. Synthesis of Analogues of Gingerol by using Bismuth Chloride,
Journal of Beijing Normal University (Natural Science) 2002, 38, 230-233.
3