Assistant Maintenance

Cristina Ricardo Carter

** ****** ******, ********* *****, NY 10567

M: 914-***-**** . Email: ********.*******.******@*****.***

LinkedIn: http://www.linkedin.com/in/cristinaricardocarter

Summary of Qualifications

. Analytical thinking skills with proficiency developing and designing

experiments

for in vivo and in vitro model systems

. Challenge-oriented with ability to take ideas from conception to

completion

. Comfortable working efficiently both independently and as part of a

project team

. Ability to manage multiple tasks/projects successfully and master new

techniques

. Extensive experience in publication writing and delivering professional

presentations

Research and Professional Experience

Regeneron Pharmaceuticals, Tarrytown, NY

Research Associate III/IV, Infectious Diseases: 2008-2014

. Investigated fungus, virus, parasite and host-derived proteins as

potential targets for bio-therapeutics

. Developed, optimized and implemented in vitro assays and in vivo

infection models for target validation and candidate antibody screening

. Responsible for routine lab management, maintenance, and adherence to BSL

2+ safety standards

. Facilitated infectious disease immunizations and downstream screening and

selection with the goal of advancing promising bio-therapeutics through the

company's pipeline and into the clinical setting

. Established functional SOPs and protocols to guide day-to-day operation

of the lab and vivarium

. Collected, analyzed and presented experimental results

. Trained, advised and mentored a temporary, contract employee in in vivo

and in vitro methodologies spanning several ongoing targets: 2013

. Mentored summer college internship students: Summer 2011, 2013, and 2014

Jacob, Medinger, and Finnegan, LLP, New York, NY

Science Information Specialist: April - November 2008

. Identified, reviewed and abstracted medical and scientific literature

relevant to the firm's product liability litigation focusing primarily on

cardiovascular disease, tumor immunology, and mechanisms of addiction

. Conducted research via literature search engines (Pubmed, LexisNexis,

etc.) for legal team on biomedical matters

. Maintained and updated firm's literature database

University of Notre Dame, Notre Dame, IN

Research Assistant, 2002 - 2007

. Elucidated the role of macrophage receptor CR3 in in vivo murine

parasitic leishmaniasis

. Investigated kinase signaling pathways and transcription factors

modulated by infection

. Examined cytokine production at transcriptional and post-translational

levels in in vitro macrophage culture and mammalian tissues

. Instructed undergraduate Microbiology and General Biology Laboratory

Optigenix, Inc., Newark, DE

Laboratory Research Assistant: 2000 - 2001

. Responsible for general lab maintenance, media preparation, and bacterial

culture

. Supported scientific staff with literature-based research

Specific SkillS

. Microscopy and Imaging: standard light microscopy; Immunofluorescence and

confocal microscopy; Molecular Devices ImageXpress platform

. Cell Culture: mammalian cell, bacteria, parasite and yeast culture; virus

isolation, quantification, and propagation; isolation/differentiation of

primary cells; maintenance of extensive cell culture lines; cellular assay

development; tissue harvesting and processing

. Molecular Biology: nucleic acid isolation, PCR, RT-PCR, Taqman,

mammalian cell transfection, amaxa Nucleofector system, bacterial

transformation, luciferase assay

. Protein Analytics: SDS-PAGE, Western Blotting, ELISA, LuminexTM

. Immunological Techniques: FACS analysis, basic histology and

immunohistochemistry

. Animal model: extensive work with murine models and in vivo infection;

proficiency in animal care, handling and manipulation including

subcutaneous, intraperitoneal, intranasal, intradermal and intravenous

injections in an AAALAC-accredited facility

. Computer skills/Software: Mac OS and Windows Platforms, MS Office,

GraphPad Prism, FlowJo

Education

M.S. University of Notre Dame, Notre Dame, IN 2008

Biological Sciences: Immunology of Infectious Disease

Thesis: The Role of Complement Receptor 3 in Immune Bias and

Macrophage Cell Signaling Modulation in Experimental Cutaneous

Leishmaniasis

B.S. University of Delaware, Newark, DE 2001

Biochemistry

Publications

Ricardo-Carter, C., M. Favila, R.E. Polando, K. Bogard Horner, D. Condon,

W. Ballhorn, J.P. Whitcomb, M. Yadav, R.L. Geister, J. Schorey, M.A

McDowell. 2013. Leishmania major infection inhibits IL-12 in macrophages by

signaling through CR3 (CD11b/CD18) and downregulation of ETS-mediated

transcription. Parasite Immunol. 35(12): 409-20.

**NOTE: This publication was the recipient of the 2014 Woods Hole

Immunoparasitology Prize

Polando, R., U.G Dixit, C.R. Carter, B. Jones, J.P. Whitcomb, W. Ballhorn,

M. Harintho, C. Jerde, M.E. Wilson, M.A. McDowell. 2013. The Roles of

Complement Receptor 3 and Fc Receptors during Leishmania Phagosome

Maturation. J Leukoc Biol. 93(6): 921-32.

Carter, C.R., J.P. Whitcomb, J.A. Campbell, R.M. Mukbel, M.A. McDowell.

2009.

Complement receptor 3 deficiency influences lesion progression during

Leishmania major infection in Balb/c mice. Infect Immun. 77(12): 5668-75.

Akilov, O.E., M.J. Donovan, T. Stepinac, C.R. Carter, J.P. Whitcomb, T.

Hasan,

M.A. McDowell. 2007. T helper type 1 cytokines and keratinocyte growth

factor

play a critical role in pseudoepitheliomatous hyperplasia initiation during

cutaneous leishmaniasis. Arch Dermatol Res. 299(7): 315-25.

Akilov, O.E., R.E. Kasuboski, C.R. Carter, M.A. McDowell. 2007. The role

of

mannose receptor during experimental leishmaniasis. J Leukoc Biol. 81(5):

1188-96.

SELECTED SCIENTIFIC CONFERENCES

. Annual Midwestern Conference of Parasitologists (AMCOP), 2002. Millikin

University, Decatur, IL.

Poster: The Role of Complement Receptor 3 in Murine Cutaneous Leishmaniasis

. Woods Hole Immunoparasitology Conference (WHIP), 2003-2004. Woods Hole,

MA.

The Role of Pattern Recognition Receptors in the Establishment and

Progression of Leishmania major Infection

. Autumn Immunology Conference (AIC), November 2003-2006. Chicago, IL.

CR3-Deficient Mice Demonstrate Increased Resistance to Leishmania major

. Chicago Area Mycology and Parasitology Meeting (CAMP), 2005-2006.

Northwestern Univeristy, Chicago, IL.

Poster: CR3-Deficiency Correlates with Heightened Resistance to Cutaneous

Leishmaniasis.

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