Quality Control Manufacturing

Raul Jackson

*** ****** **.

East Boston, MA ****8

*******@*****.***

Dear Hiring Manager:

I am a skilled research/manufacturing Scientist with a B.S. in Chemical Engineering from Drexel University. I have several years of

hands on experience in radiopharmaceutical development along with GMP manufacturing and quality control. I am seeking to align

myself with an institution that is poised for growth and success. Your job opportunity presents the sort of career challenge I am

seeking. Ingenuity and versatility are key qualities that I possess and combined with my experience and academic background makes

me a valuable asset.

I am currently employed as a PET Manufacturing Chemist at Massachusetts General Hospital where, in addition to gaining experience

in 11C and 13N radiochemistry, I served as lead scientist and key contributor for the 18F FPEB and 18F T807 PET tracer synthesis

development and validation projects respectively.

As a Radiopharmaceutical Development Scientist at Avid Radiopharmaceuticals I gained hands-on experience in 18F and 125I

radiochemistry and synthesis processes and working conjunction with the Senior Radiochemist on process development and

optimization projects. I also worked in a GMP manufacturing environment producing and dispensing clinical trial

radiopharmaceuticals for shipment. In February 2011 I obtained my RSO certification from Dade Moeller Radiation Safety Academy

and served as the Assistant RSO to the facility. As assistant RSO I authored, revised, and updated radiation safety SOPs, provided

radiation safety training for applicable new-hires, managed employee dosimetry records, and conducted program audit for 2010. My

RSO duties also included performing routine thyroid bioassays and radioactive waste management.

Through my internships with DuPont Environmental Treatment (DET) Waste Acceptance Laboratory, I gained laboratory experience

in wet chemistry, gas chromatography, and mass spectroscopy. My academic training allowed me to apply my analytical, problem

solving, and computer skills to develop an on-line predictive computer model that enabled a more effective real-time control of

hazardous air pollutants (HAPs) discharged into DET treatment facilities. The model also allowed DET to proactively market HAPs

business to new customers.

During my undergraduate and graduate research projects, I gained experience in protein immobilization techniques, biosensing

technology, and technical writing. These experiences also allowed me to participate in research conferences where I presented my

research.

My above experiences helped me develop strong abilities to work accurately with minimal supervision and under pressure in a fast-

paced environment. I consider myself a driven and energetic team player, capable of functioning as a contributing member as well as

a leader. I am very enthusiastic about bringing my energy and my eagerness to work and learn and would greatly appreciate an

opportunity to further discuss my qualifications. I have attached my resume for your review; should you require any additional

information, please do not hesitate to contact me at *******@*****.*** or at 718-***-****. Thank you for your time and

consideration. I look forward to hearing from you in the near future.

Regards,

Raul Jackson

Enclosures: Resume

Raul N. Jackson

309 Sumner St.

East Boston, MA 02128

(718) – 781 – 2032

*******@*****.***

Education:

September 1998 - Drexel University, Philadelphia, PA

June 2003 Bachelor of Science in Chemical Engineering

Graduated: 06/2003

Work Experience:

March 2012 – Massachusetts General Hospital

Present Division of Nuclear Medicine and Molecular Imaging

Department of Radiology

Boston, MA

PET Radiopharmaceutical Manufacturing Chemist

Provide reliable synthesis, quality control, and release of 11C PIB, 11C Altropane, 11C

Raclopride, 18F FDG, 18FES, 18F FPEB, and 18F T807 radiopharmaceuticals for hospital

studies.

Provide reliable quality control, and release of 13N N2 (in saline) radiopharmaceutical for hospital

studies.

Perform aseptic filling and compounding operations in a GMP clean room environment.

Served as lead scientist for 18F FPEB synthesis development project on the FXF-N

radiosynthesizer.

Work in conjunction with senior radiochemist and nuclear pharmacists on process development

and optimization projects (i.e. process design, reaction conditions, HPLC purification, and

formulation development).

Perform 18F and 11C radiosyntheses of experimental compounds using the FXF-N, FXC, and

FASTlab radiosynthesizers for preclinical evaluation.

Perform maintenance and calibration of manufacturing and quality control equipment.

Assist with maintenance and environmental monitoring of GMP clean room and production

facility.

Administer aseptic operator qualification.

Manage environmental monitoring and aseptic operation records.

Author, revise, and update manufacturing and quality control SOPs.

Provide manufacturing and quality control training for team new-hires.

February 2008 – Avid Radiopharmaceuticals

February 2012 (a wholly-owned subsidiary of Eli Lilly & Company)

Philadelphia, PA

Radiopharmaceutical Development Scientist

Worked in conjunction with senior radiochemists on process development and optimization

projects (i.e. process design, reaction conditions, HPLC purification, formulation development).

Performed 18F radiosyntheses of experimental compounds using automated the FXF-N, MX,

FDG-Plus, and Neptis radiosynthesizers for preclinical evaluation.

Performed routine manual 125I radioiodinations of experimental compounds for pre clinical

evaluation.

Performed reliable synthesis of Florbetapir 18F (Amyvid) and 18F-AV-133 radiopharmaceuticals

for clinical trial studies.

Performed in aseptic filling and compounding operations operation in a GMP clean room

environment.

Assisted with maintenance and environmental monitoring of GMP clean room and manufacturing

facility.

Assisted with maintenance and calibration of manufacturing and radiation safety equipment.

Served as Assistant RSO to the site.

Managed Radiation Safety Program.

Authored, revised, and updated manufacturing and radiation safety SOPs.

Administered manufacturing training to team new-hires.

Administered radiation safety training to applicable employees.

Managed laboratory and manufacturing inventory control.

June 2007 – Fuji Film Imaging Colorants, Inc.

September 2007 QC Laboratory, New Castle, DE

QC Technician

Performed physical property analyses on ink and dye samples.

Updated sample results and instrument calibration data in LIMS.

September 2002 – DuPont Environmental Treatment (DET) –

February 2003 Waste Acceptance Laboratory, Deepwater, NJ

(Part-Time) DET Co-op

Performed GC/MS analyses on incoming waste stream samples for hazardous air pollutants

(HAPs)

Monitored wastewater treatment plant emissions of HAPs via computer model

Updated and validated laboratory methods for analyzing wastewater

September 2001 – DuPont Environmental Treatment (DET) –

March 2002 Waste Acceptance Laboratory, Deepwater, NJ

DET Co-op

Designed and managed pilot plant experiments for caustic refinery waste oxidation

Improved HAPs sampling program for contract waste streams

Monitored wastewater treatment plant emissions of HAPs via computer model

Developed database for tracking laboratory overtime distribution

Reduced laboratory overtime costs by 22%

September 2000 – DuPont Environmental Treatment (DET) –

March 2001 Waste Acceptance Laboratory, Deepwater, NJ

DET Co-op

Designed HAPs emissions tracker for wastewater treatment plant

Developed and implemented new HAPs sampling program

Performed GC/MS analyses on incoming waste stream samples for HAPs

Monitored wastewater treatment plant emissions of HAPs via computer model

Improved HAPs management

August 1999 – DuPont Performance Chemicals (PC), Deepwater NJ

March 2000 PC Co-op

Designed and implemented electronic performance support system (EPSS)

Developed project plan for storage tank decontamination

Publications:

S. H. Liang, D. L. Yokell, R. N. Jackson, P. A. Rice, R. Callahan, K. A. Johnson, D. Alagille, G.

Tamagnan, T. Lee Collier and N. Vasdev, Microfluidic continuous-flow radiosynthesis of [18F]FPEB

suitable for human PET imaging Med. Chem. Commun., 2014, 5, 432

Shoup, T. M., Yokell, D. L., Rice, P. A., Jackson, R. N., Livni, E., Johnson, K. A., Brady, T. J. and Vasdev,

N. (2013), A concise radiosynthesis of the tau radiopharmaceutical, [18F]T807. J Label Compd Radiopharm,

56: 736–740. doi: 10.1002/jlcr.3098

Research Experience:

March 2005 – Detection of pathogens using magnetoelastic resonance (MeR) sensors

December 2006 Model Pathogens: E. coli O157:H7 and Bacillus anthracis

Worked in conjunction with senior engineer on bioterrorism project at Drexel University

Designed and fabricated MeR sensors

Characterized and immobilized recognition molecules (antibodies) on the sensor

Designed and executed detection experiments

Software &

Laboratory Hardware

Experience:

Microsoft Office Applications: Excel, Word, PowerPoint

Laboratory Hardware: FDG-Plus, Neptis, and TRACERlab MX, FXC, and FX F-N Radiosynthesizers,

Agilent Technologies 1200 Series LC system, Waters e2695 LC system, Bioscan AR-2000 radio-TLC

Imaging Scanner, Perkin Elmer 1480 Automatic Gamma Counter

Certifications: 2011 Radiation Safety Officer with DOT Certification – Dade Moeller Radiation Safety Academy,

Gaithersburg, MD

2011 DOT, NRC & IATA Requirements for Shipping Radioactive Material – Dade Moeller Radiation

Safety Academy, Gaithersburg, MD

Honors:

2006 2nd Place - 9th Annual Alliance for Minority Participation (AMP) Research Symposium and Mentoring

Conference

2003 National Science Foundation Bridge to the Doctorate Fellowship Recipient

2003 Philadelphia AMP Excellence Award Recipient

2003 1st Place - 7th Annual AMP Research Symposium and Mentoring Conference

2002 DuPont Chemical Solutions Enterprise (DCSE) Technology Excellence Award Recipient

2002 DuPont Six Sigma Appreciation Award Recipient

2002 DuPont Engineering Excellence Award Finalist

2002 DET Achievement Award Recipient

2001 DET “Kudos” Award Recipient

Activities:

Alpha Phi Alpha Fraternity Inc.

Gamma Theta Lambda Chapter, Wilmington, DE

University of Delaware Step Team Coordinator, 2004 – 2008

Contact this candidate