Research Associate/ Quality Control

*** ********** ***. ***#*, Albany, NY – ***** ******.***@*****.*** 518-***-****

DRUSHA PUROHIT

Intellectually curious and driven by strong morals, I am passionate about my work. I am seeking a

OBJECTIVE

position in drug development and assessment in pharma/biotech organization of repute wherein I can

get an opportunity to utilize my scientific knowledge and technical skills in a group or individually,

while being able to grow professionally.

ALBANY COLLEGE OF PHARMACY AND HEALTH SCIENCES – ALBANY, NY

EDUCATION

Master of Sciences in Pharmaceutical Sciences (Candidate)

Graduation: August 16, 2014 OPT start date- August 18, 2014

Thesis Title: “Determination of Synergistic Antioxidant Activity of α- and δ Tocopherylcarbamate

Co-Drugs on UV-induced Lipid in Skin”

cGPA: 3.7/4.0

DR. BHANUBEN NANAVATI COLLEGE OF PHAMACY, UNIV. OF MUMBAI, MUMBAI,

INDIA

Bachelor of Pharmacy

Graduation: May 2012

GRADUATE RESEARCH ASSISTANTSHIP JAN 2014

EXPERIENCE

– MAY 2014

• Evaluated antioxidant activity of the co-drugs to inhibit lipid peroxidation induced using

solar simulator

• Performed protein normalization using BCA protein assay

• Developed method for inducing protein oxidation in skin using UVR, and confirmed using

gel electrophoresis followed by Western Blots.

GRADUATE RESEARCH ASSISTANTSHIP OCT 2013

– DEC 2013

• Determined the dose of UVR required to induce lipid peroxidation in porcine skin using

solar simulator

• Performed co-drug penetration studies (in vitro studies) using Franz Diffusion Cell

GRADUATE RESEARCH ASSISTANTSHIP FEB 2013

– MAY 2013

• Synthesized one of the parent compounds using wet chemistry method and analyzed it

using Thin Layer Chromatography (TLC), Fourier Transform Infrared (FTIR) Spectroscopy

and Nuclear Magnetic Resonance (H-NMR/C-NMR)

• Purified the parent compound using Flash Column Chromatography

• Developed method for thiobarbituric acid reactive substances (TBARS) assay to evaluate

the antioxidant activity of co-drugs as well as the parent compounds to inhibit lipid

peroxidation in porcine skin.

• Prepared samples and measured the antioxidant activity of co-drugs and parent compounds

using UV-Vis Spectrophotometer and its extent of hydrolysis using High Performance

Liquid Chromatography (HPLC).

• Developed method to determine appropriate solvent system for detection of compounds in

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HPLC.

• Plotted the standard curves for the co-drugs and its parent compounds using Origin Pro 8

and Microsoft Office

• Demonstrated the synergism between the parent compounds and determined its

experimental significance using t-test and ANOVA.

LABORATORY ROTATION AUG 2012

- DEC 2012

• Learnt aseptic techniques, mammalian cell culture, cell counting and cell treatment

techniques.

• Induced oxidation in cells and performed Thiobarbituric acid reactive substances (TBARS)

assay on them to verify induction of oxidation

RESEARCH TRAINEE MAR 2012

– MAY 2012

• Maintenance of diabetes induced rats

• Animal handling and oral dosing of rats

INTERN, SHREECHEM PHARMACEUTICAL PVT. LTD. MAY 2011 –

JUNE 2011

• Studied industrial manufacturing processes (Raw material handling, record keeping,

formulation, packaging, quality control and quality assurance) of tablets, capsules, sterile

products, and ophthalmic

• Submitted a detailed report of the experience of the working of industrial processes

TRAINEE & OBSERVER, SUVIDHA HOSPITAL

DEC 2010

• Learned about dispensing of drugs.

OTHER LAB MRNA ISOLATION, PROTEIN ASSAY ON MAMMALIAN CELLS, DISSOLUTION

TESTING, PARTICLE SIZE TESTING

TECHNIQU

ES

SOFTWARES SYBYL (Intermediate Level), ChemDraw, OriginPro 8, Microsoft Office.

Graduate Research Supplies Award – June 2013 to April 2014

AWARDS

Best Group Project - “Higher Studies Abroad”, March 2011

“Inhibition of UVR-induced Lipid Peroxidation in Skin by Novel Co-drugs”

PEER

REVIEWED

17th American Association of Pharmaceutical Scientists – Northeast Regional Discussion Group

PRESENTAT

Research Project Poster – Regional Meeting May

ION

2014

“Inhibition of Lipid Peroxidation with Carbamate Co-drugs”

th

247 American Chemical Society – National Meeting and Exposition

Research Project Poster – National Meeting March 2014

“Plastic antibodies saves mice, are humans next?”

Indian Pharmaceutical Association – Maharashtra State Branch – Student’s Forum Technical Festival

Review Poster Presentation - Regional Conference January

2011

“Immune Cells trained to kill Cancer Cells”

Manshodhan 2011

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Review Paper Presentation – Intercollegiate Research Fair (1st Runner up) December 2011

• Dr. Martha A Hass – Associate Professor in Chemistry Dean, School of Graduate Studies

REFERENCES

Albany College of Pharmacy and Health Sciences, Albany, NY.

******.****@*****.*** 518-***-****

• Dr. Siji Thomas – Postdoctoral Fellow Hass Laboratory

Albany College of Pharmacy and Health Sciences, Albany, NY.

****.******@*****.*** 518-***-****

• Dr. Lokeshkumar Bhatt – Assistant Professor, Department. of Pharmacology

Dr. Bhanuben Nanavati College of Pharmacy, University of Mumbai, Mumbai, India.

******.*****@****.**.**

P.S. Open to relocation without assistance.

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