Attending staff(IONM)
Resume:
Yuangen Chen
ACADEMIC APPOINTMENTS
Assistant Professor Department of Neurosurgery, the Mount
Sinai School of Medicine
New York, NY 10029
(September, 2007- Present)
Research Associate Department of Microbiology and Immunology,
New York Medical
College New York, NY 10595
(2001-2005)
Associate Professor Division of Gastroenterology, Huashan
hospital, Shanghai, China
(1996-1998)
Assistant Professor Division of Gastroenterology, Huashan
hospital, Shanghai, China
(1994-1996)
HOSPITAL APPOINTMENTS
Attending staff (IOM) Department of Neurosurgery, the Mount Sinai
Hospital
New York, NY 10029 (December,
2007- Present)
Assistant Attending Department of Neurosurgery, the Mount
Sinai Hospital
New York, NY 10029
(September, 2005- Dec. 2007)
Research Coordinator Department of Neurosurgery, Mount Sinai
School of Medicine
New York, NY 10029 (January,
2005-Sept.2005)
Associate Professor Division of Gastroenterology, Huashan
hospital, Shanghai, China
(1996-1998)
Assistant Professor Division of Gastroenterology, Huashan
hospital, Shanghai, China
(1994-1996)
EDUCATION
Ph.D. Division of Gastroenterology, Huashan hospital, Shanghai, China
(1994)
M.D. Jiangxi Medical College, Jiangxi, China (1986)
POSTDOCTORAL TRAINING
Postdoctoral fellow Department of Microbiology and Immunology,
New York Medical
College, New York (1998-
2001)
Residency Department of Medicine, Dongxiang Hospital, Jiangxi,
China (1986-1989)
HONORS/AWARDS
ABNM Member eligible (written part exam passed)
ASNM Member American Society of Neurophysiological Monitoring
(2005-Present)
CNIM Certificate (#1132) (2006-2016)
95-96's Excellent Physician Hushan Hospital, Shanghai, China
(1996)
Top Prize the third national award of Omeprazole research,
Chinese Digestive Association,
Wuhan, China (1995)
EXPERIENCES (2005, Jan.-Present)
Supervising intraoperative monitoring of brain, spinal cord, and peripheral
nervous system during neurosurgical procedures using somatosensory evoked
potentials (SSEPs), brainstem auditory evoked potentials (BAEPs), motor
evoked potentials (MEPs), electroencephalogram (EEG), as well as free-run
and electrically-triggered electromyography (EMG) for monitoring segmental
motor nerve root function
PUBLICATIONS
Peer Reviewed Original Contributions
1. Kumar A, Chen Y, Lin HM, Deiner S. Elevated preoperative blood
pressure predicts the intraoperative loss of SSEP neuromonitoring
signal during spinal surgery. J Clin Monit Comput. 28:187-192(2013)
2. Tadi K, Ashok BT, Chen Y, Banerjee D, Wysocka-Skrzela B, Konopa J,
Darzynkiewicz Z, Tiwari RK. Pre-clinical evaluation of 1-
nitroacridine derived chemotherapeutic agent that has preferential
cytotoxic activity towards prostate cancer. Cancer biology & therapy.
Oct.6(10):1632-1637(2007)
3. Ashok B.T., Tadi K, Garikapaty, V.P.S., Chen Y., Huang Q., Banerjee
D., Konopa J., Tiwari R.K. Preclinical toxicological examination of a
putative prostate cancer-specific 4-methyl-1-nitroacridine derivative
in rodents. Anticancer Jan;18(1):87-94(2007)
4. Tadi K, Chang Y, Ashok B.T., Chen Y, Moscatello A, Schaefer S.D.,
Schantz S.P., Policastro A.J., Geliebter J, Tiwari R.K. 3,3'-
Diindolylmethane, a cruciferous vegetable derived synthetic anti-
proferative compound in thyroid disease. Biochem Biophys Res Commun.
Nov 25;337(3):1019-25 (2005)
5. Suriano R, Ghosh S.K., Ashok B.T., Mittelman A, Chen Y.G., Banerjee
A, Tiwari R.K. Differences in Glycosylation Patterns of Heat Shock
Protein, gp96: Implications for Prostate Cancer Prevention. Cancer
Res. Jul 15; 65(14): 6466-75 (2005)
6. Garikapaty, V.P.S., Ashok, B.T., Chen, Y.G., Mittelman, A.,
Iatropoulos, M., and Tiwari R.K. Anti-carcinogenic and anti-
metastatic properties of indole-3-carbinol in prostate cancer. Oncol
Rep. Jan; 13(1):89-93 (2005)
7. Chen, Y.G., Ashok, B.T., Liu, X., Garikapaty, V.P.S., Mittelman, A.
and Tiwari, R.K. Induction of heat shock protein, gp96, by immune
cytokines. Cell Stress & Chaperones 8(3), 242-248 (2003)
8. Ashok, B.T., David, L., Chen, Y.G., Garikapaty, V.P.S., Chander, B.,
Kanduc, D., Mittelman, A. and Tiwari, R.K. Peptide mimotopes of
oncoproteins as therapeutic agents in breast cancer. Int. J. Mol.
Med. 11: 465-471 (2003)
9. Ashok, B.T., Chen, Y.G., Liu, X., Garikapaty, V.P.S., Seplowitz, R.,
Tschorn, J., Roy, K., Mittelman, A. and Tiwari, R.K. Multiple
molecular targets of indole-3-carbinal, a chemopreventive
antiestrogen in breast cancer. Eur. J. Cancer Prev. 11: S86-S93
(2002)
10. Ashok, B.T., Chen, Y.G., Liu, X., Bradlow, H.L., Mittelman, A. and
Tiwari, R.K. Abrogation of estrogen mediated cellular and
biochemical effects by indole-3-carbinol.
Nutrition and Cancer. 41: 180-187 (2002)
11. Wang, L., Lu, W., Chen, Y.G., Zhou, X.M. and Gu, J.R. Comparision of
gene expression between normal colon mucous and colon
carcinoma by means of messenger
RNA differential display. World Journal of Gastroenterology.
15(4): 26-27 (1999)
12. Wang, L., Lu, W., Chen, Y.G., et al, Establishment of the technique
of mRNAs differential display for human normal colon
mucous and colon cancer. Chinese Journal
of Experimental Surgery. 15(4): 306-307 (1998)
13. Wang, L., Lu, W., Chen, Y.G., Identification of differences between
normal and carcinomatous colorectal mucosa by mRNA differential
display. Acta Academiae Medicinae Shanghai. 25(6): 49 (1998)
14. Chen, Y.G., Lu, W., Lin, S.Y., The effect of endothelin on acute
gastric mucosa damage. Shanghai Medicine. 21(5): 261-263
(1997)
15. Chen, Y.G., Lu, W., Lin, S.Y., The effect of endothelin on gastric
mucosa Na/K ATPase
activity. Journal of Shanghai Medical University. 16:189-191
(1997)
16. Chen, Y.G., Lu, W., Lin, S.Y., The effect of Sodium nitroprusside on
endothelin-induced
gastric mucosa injury. Acta Academic Medicine Shanghai.19 (5):
266-268 (1996)
17. Wang, L., Chen, Y.G., Lu W., Preventive effect of CBS against acute
gastric mucosa injury in rats. Chinese J Gastroenterol.
1(2): 98-102 (1996)
18. Chen, Y.G., Lu, W., The effect of colloidal bismuth subcitrate on
ethanol induced gastric mucosa damage. Acta Academic
Medicine Shanghai. 22(supplement):125- 127 (1995)
Books
Lu, W., Chen, Y.G., Hematemesis and Hematochezia. Shanghai
Scientific and
Technological Publishing House. ISBN 7-5323-5179/R.1306 (Book
1999 in Chinese)
ABSTRACTS AND MEETING PRESENTATIONS
The 5th International Symposium on Intraoperative Neurophysiological
Monitoring (IONM)
(November 6-18, 2006, New York)
18th Annual Meeting (ASNM) (May 3-6, 2007, Chicago)
19th Annual Meeting (ASNM) (May 2-4, 2008, Chicago)
21th Annual Meeting (ASNM) (May 4-6, 2010, Vancouver)
23th Annual Meeting (ASNM) (May 5-7, 2012, Salt Lake City)
1. Chen, Y.G., Suriano, R., Liu, X.Y., Tadi, K., Ashok, B.T., Garikapaty,
V.P.S., Narayanan, R., and Tiwari, R.K. Genomic and proteomic
profiling of the molecular targets of a novel anti-prostate cancer
drug 1-nitroacridine. Proceedings of the American Association for
Cancer Research 45:264 (2004)
2. Tadi, K., Chen, Y.G., Ashok, B.T., Garikapaty, V.P.S., Banerjee, D.,
Wysocka-Skzrela, B., Konopa, J., and Tiwari, R.K. Capridine (C-1748):
A novel 1-nitroacridine derivative targets the cyclin dependent
kinase, cdk4, and the tumor suppressor gene, p16 in prostate cncer.
Proceedings of the American Association for Cancer Research 45:223
(2004)
3. Garikapaty, V.P.S., Ashok, B.T., Chen, Y.G., Mittelman, A., and
Tiwari, R.K. Anti-prostate cancer activity of Indole-3-carbinol (I3C)
and Diindolylmethane (DIM) is by inhibition of the Akt signal.
Proceedings of the American Association for Cancer Research 45:178
(2004)
4. Suriano, R., Ghosh, S.K., Chen, Y.G., Ashok, B.T., Banerjee, A., and
Tiwari, R.K. Glycosylation patterns associated with heat shock
protein, Gp96, contributes to its tissue specificity. Proceedings of
the American Association for Cancer Research 45:372 (2004)
5. Chen, Y.G., Ashok, B.T., Garikapaty, V.P.S., Banerjee, D., Konopa, J.,
Miller, D.G., Iotropoulos, M and Tiwari, R.K. Pre-clinical toxicology
and pathology of capridine, a novel anticancer agent in dogs.
Proceedings of the American Association for Cancer Research 44:372
(2003)
6. Narayanan, R., Tiwari, P., Wysocka-Skzrela, B., Konopa, J., Chen,
Y.G., Ashok, B.T. Mutagenicity of 1-nitro-9 hydroxyalkylamino acridine
derivatives using Ames test. Proceedings of the American Association
for Cancer Research 44:372 (2003)
7. Chen, Y.G., Ashok, B.T., Garikapaty, V.P.S., Liu, X.Y., Szostek, A.,
Wysocka-Skrzela,B., and Tiwari R.K. Pre-clinical studies of 1-
nitroacridine derivatives: Effective anti-tumor agents for prostate
cancer. Proceedings of the American Association for Cancer Research
43:77 (2002)
8. Chen, Y.G., Ashok, B.T., Garikapaty, V.P.S., Mittelman, A., and Tiwari
R.K. Cytokines mediated regulation of heat shock protein gp96.
Proceedings of the 17th Annual Scientific Meeting of the Society for
Biological Therapy, San Diego, CA, November 7-10. J. Immunother. 25
(6): S29 (2002)
9. Garikapaty, V.P.S., Ashok, B.T., Chen, Y.G., Lai, J., Mittelman, A.,
and Tiwari R.K. Anti-tumor activity of indole-3-carbinol in prostate
cancer. Proceedings of the American Association for Cancer Research
43:641 (2002)
10. Ashok, B.T., Chen, Y.G., Garikapaty, V.P.S., Mittelman, A., and Tiwari
R.K. Single chain antibodies (scFv) isolated from a phage display
library as a tool to identify unique gp96 associated peptide antigens.
Proceedings of the American Association for Cancer Research 43:969
(2002)
11. Ashok, B.T., Chen, Y.G., Mittelman, A. and Tiwari, R.K. synthetic
peptide mimotopes reacting to single chain antibodies (scFv) directed
against tumor rejection antigen gp96 as novel immunogens. Proceedings
of the American Association for Cancer Research 42:680-681 (2001)
12. Liu, X., Chen, Y.G., Ashok, B.T., Tschorn, J.,Roy, K.,Mittelman,A and
Tiwari R.K.
Modulation of gene expression by dietary factors in human breast
cancer. Proceedings of
the American Association for Cancer Research 42:655 (2001)
13. Chen, Y.G., Xinyan Liu, Abraham Mittelman, and Tiwari, R.K. Cytokine
mediated
regulation of the heat shock protein gp96. Proceedings of the
American Association for
Cancer Research 41:191 (2000)
14. Ashok, B.T., Chen, Y.G., Liu, X., Mittelman, A. and Tiwari, R.K.
Phyotantiestrogen: Cellular and molecular effects in breast cancer.
Proceedings of the American Association for Cancer Research 41:660
(2000)
15. Ashok, B.T., Chen, Y.G., Liu, X., Mittelman, A. and Tiwari, R.K.
Identification of prostate cancer associated immunogens using
synthetic combinatorial single chain (scFv) phage display antibody
library. Proceedings of the American Association for Cancer Research
41:698-699 (2000)
16. Chen, Y.G., Noronha, J., Yedavelli, S.P.K., Mittelman, A. and Tiwari,
R.K. The peptide chaperone gp96 is associated with HLA class I.
Proceedings of the American Association for Cancer Research 40:566.
(1999)
17. Ashok, B.T., Yedaveli, S.P.K., Chen, Y.G., Mittelman, A. and Tiwari,
R.K. Identification of novel tumor rejection antigenic epitopes using
synthetic single chain (scFv) combinatorial phage display antibody
library. Proceedings of the 4th World Congress on Advances in Oncology
and 2nd International Symposium on Molecular Medicine organized by the
International Journal of Oncology, Oncology Reports and International.
Journal of Molecular Medicine, Athens, Greece, October 7-9R (1999)
18. Chen, Y.G., Lu, W., Lin, S.Y., The effect of Omeprazole on endothelin-
induced gastric mucosa injury. Journal of Gastroenterology and
Hepatology. 10(supplement4): A168 (1995)
Reference: on demand
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