College University

Mariluz Henshaw, M.D., Ph.D

**** *. ********* **., **** Lake City, UT 84106

Phone: 801-***-**** Email: *******.*******@*****.***

HEALTH CARE PROFESSIONAL RESEARCH SPECIALIST

Charismatic and diligent medical professional with specialization in human genetics and regenerative medicine.

Ability to optimize experimental approaches while paying keen attention to scientific integrity. Client-focused leader

who is able to organize and deliver projects on time and within budget. Scientific accomplishments include the

successful manufacturing of human mesenchymal stem cells (hMSCs) grown in pooled human platelet lysate to treat

patients at high-risk for developing acute kidney failure after undergoing on-pump cardiac surgery.

AREAS OF STRENGTH

Clinical-Grade Cell Mfg. Regenerative Medicine Stem Cell Research

Assay Development Hematology Biotechnology

Strategic Funding FDA Submissions Teaching/Education

PROFESSIONAL EXPERIENCE

2012 - April 2014 Research Scientist

University of Utah Cell Therapy & Regenerative Medicine Facility

2007 - 2012 Stem Cell Specialist

University of Utah Cell Therapy & Regenerative Medicine Facility

2004 - 2007 Research Associate

University of Utah Division of Hematology, School of Medicine

1996 - 2003 Associate Professor

College of Medicine, University of Philippines

1987 - 1996 Assistant Professor

College of Medicine, University of Philippines

EDUCATION & TRAINING

1994 - 2000 Ph.D. in Human Genetics

University of Utah Salt Lake City, UT

Dissertation: “Isolation & Characterization of Early B Lymphoid Progenitor Cell Populations”

1990 – 1991 Research Fellowship in Immunology

Kobe University School of Medicine Kobe, Japan

1986 – 1987 Internship in Internal Medicine

Philippine General Hospital Manila, Philippines

1982 – 1986 M.D.

College of Medicine, University of the Philippines Manila, Philippines

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1978 – 1982 Bachelor of Science, Biology (magna cum laude)

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College of Arts and Sciences, University of the Philippines Quezon City, Philippines

HONORS & SCHOLARSHIPS

1994 - 1999 Fulbright Scholarship

1990 - 1991 Japan Ministry of Education & Culture (Monbusho) Scholarship

1982 - 1986 Eusebio Garcia – Class 1936 Foundation Scholarship (Medical Degree)

1978 - 1982 Philippine National Science & Development Board (Undergrad)

PUBLICATIONS

Mojica-Henshaw MP, Jacobson P, Morris J, Pierce J, Kelley LL, Boyer M, Reems JA. Serum-converted platelet lysate

can substitute for fetal bovine serum (FBS) in human mesenchymal stem cell cultures. Cytotherapy, 2013; 15:1458-1468.

Mojica-Henshaw MP, Fischer SE, Zhao Y, Kelley LL, Boyer M. Comparative Analysis of Ex Vivo Expanded Human

CD34+ Hematopoietic Stem Cells on NANEX™ Nanofiber Plates. ISSCR 2013.

Mojica-Henshaw MP, Morris J, Gulati P, Pierce J, Kelley LL, Boyer M. Development of a closed filtration system for

batch processing of pooled platelet lysate. ISCT 2012.

Morris J, Johnston C, Bullough J, Mojica-Henshaw MP, Pierce J, Wagner S, Kelley LL. The effect of freezing

temperature on growth factor levels and particulate contamination during platelet lysate production. ISCT 2011.

Morgan J, Bullough J, Hammond L, Martinez H, Mojica-Henshaw MP, Hogan M, Dunn P, Kelley L. Advanced

technology for storage and transport of purified DNA from umbilical cord blood prior to use in human leukocyte

antigen typing and whole genome microarray analysis. Biopreservation and Biobanking. 2010; 8(3): 134-8.

Bullough J, Tahan V, Morris J, Mojica-Henshaw MP, Jacobson P and Kelley L. Establishing a cord blood sample

repository for a personalized medicine initiative. ISCT 2010.

Johnston C, Morris, J, Mojica-Henshaw MP and Kelley L. Development of a xeno-free microcarrier-based human

mesenchymal stem cell expansion system. ISCT 2010.

Agarwal N, Kutlar F, Mojica-Henshaw MP, Ou CN, Gaikwad A, Reading NS, Bailey L, Kutlar A, Prchal JT. Missense

mutation of the last nucleotide of exon 1 (G->C) of beta globin gene not only leads to undetectable mutant peptide and

transcript but also interferes with the expression of wild allele. Haematologica. 2007; 92(12):1715-6.

Agarwal N, Mojica-Henshaw MP, Simmons ED, Hussey D, Ou CN, Prchal JT. Familial polycythemia caused

by a novel mutation in the beta globin gene: essential role of P50 in evaluation of familial polycythemia.

Int J Med Sci. 2007; 4(4):232-6.

Percy MJ, Sanchez M, Swierczek S, McMullin MF, Mojica-Henshaw MP, Muckenthaler MU, Prchal JT, Hentze MW.

Is Congenital Secondary Erythrocytosis/ Polycythemia Caused by Activating Mutations within the HIF-2{alpha}

iron-responsive element? Blood 2007; 110(7):2776-2777.

Mojica-Henshaw MP and Prchal JT. Uniparental Disomy in Polycythemia Vera and Other Malignancies. The

Hematologist 2007; 4(1):7.

Mojica-Henshaw MP, Laverdiere C, Prchal JF, Prchal JT. Recurrent De Novo Mutations of EPOR Gene in Primary

Congenital Polycythemia. Blood 2006; 108: 1297.

Agarwal N, Mojica-Henshaw MP, Kutlar F, Gaikwad A, Ou CN, Kutlar A, Prchal JT. Novel Mechanism of ß0

Thalassemia: Missense Mutation of the Last Nucleotide of ß Globin Exon 1 (G->C) Leads to Undetectable

Transcript and Mutant Peptide. Blood 2006; 108: 1598.

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(PUBLICATIONS CON’T)

Mojica-Henshaw MP, Huang X, Spangrude GJ. Derivation of lymphoid lineage Cells from human embryonic stem

cells. Blood 2005; 106: 3619.

Mojica-Henshaw MP, Pierce LJ, Phillips JD, Planelles V, Spangrude GJ. Clonal marking of mouse hematopoietic stem

and lymphoid progenitor cells. Blood 2005; 106: 5544.

Mojica-Henshaw MP, Francisco AD, de Guzman F, Tigno XT. Possible immunomodulatory actions of Carica papaya

seed extract. Clin Hemorheol Microcirc 2003; 29: 219-29.

Slayton WB, Mojica MP, Pierce LJ, Spangrude GJ. Observations of residual differentiation potential during lineage co

mmitment. Ann N Y Acad Sci. 2001; 938: 157-65; discussion 165-6.

Mojica MP, Perry SS, Searles AE, Elenitoba-Johnson KS, Pierce LJ, Wiesmann A, Slayton WB, Spangrude GJ. Phenotyp

ic distinction and functional characterization of pro-B cells in adult mouse bone marrow. J Immunol. 2001; 166(5): 3042

-51.

Searles AE, Pohlmann SJ, Pierce LJ, Perry SS, Slayton WB, Mojica MP, Spangrude GJ. Rapid B lymphoid-restricted

engraftment mediated by a primitive bone marrow subpopulation. J Immunol. 2000; 165(1): 67-74.

Wiesmann A, Phillips RL, Mojica MP, Pierce LJ, Searles AE, Spangrude GJ, Lemischka I. Expression of CD27 on muri

ne hematopoietic stem and progenitor cells. Immunity 2000; 12(2): 193-9.

Mojica MP, Perry S, Searles AE, Pierce LJ, Elenitoba-Johnson K, Spangrude GJ. Isolation of committed B lymphoid pro

genitor cells prior to B220 expression from adult mouse bone marrow. Blood 1999; 94(10): 682a.

Ivanova N, Phillips RL, Mojica MP, Spangrude GJ, Lemischka I. Identification of common gene expression profiles in

murine fetal liver and adult bone marrow stem cells. Blood 1999; 94(10): 254a.

Wiesmann A, Phillips RL, Mojica MP, Pierce LJ, Searles AE, Spangrude GJ, Lemischka I. CD27 expression on mouse h

ematopoietic stem cell and progenitor cells: functional analysis of subpopulations. Blood 1999; 94(10): 681a.

Mojica MP, Perry S, Pohlmann S, Searles AE, Elenitoba-Johnson K, Spangrude GJ. Isolation of bipotent lymphoid-mye

loid progenitor cells from normal mouse bone marrow. Blood 1998; 92(10): 23a.

Phillips RL, Mojica MP, Spangrude GJ, Lemischka I. Interrogating large sequence databases for novel genes expressed

in different compartments of the hematopoietic hierarchy. Blood 1998; 92(10):572a.

Fujita K, Miki N, Mojica MP, Takao S, Phuchareon J, Nishikawa S, Sudo T, Tokuhisa T. B cell development is perturbe

d in bone marrow from c-fos/v-jun doubly transgenic mice. Int Immunol. 1993; 5(2): 227-30.

COURSES TAUGHT

“Special Topics in Biotechnology & Stem Cell Biology”- Biotechnology Program, Utah Valley University, Winter 2010.

“Stem Cells and Cell-based Therapies”- Advanced Hematology Class, University of Utah, Fall 2008-2011.

“Stem Cells and Regenerative Medicine”- Biotechnology Program, Utah Valley University, Winter 2008.

Human Biochemistry – College of Medicine, University of the Philippines, 1987-1994, 2000-2003.

“Introduction to Patient Care” – College of Medicine, University of the Philippines, 1988-1990, 1992-1994

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Pedagogy – College of Medicine, University of the Philippines, 1993-1994, 2000-2003.

(COURSES TAUGHT CON’T)

Research Methods – College of Medicine, University of the Philippines, 1993-1994, 2000-2003.

Biochemistry – College of Medicine, University of the Philippines, 1991-1994, 2000-2003.

Human Molecular Genetics – College of Medicine, University of the Philippines, 2000-2003.

Special Topics Course – College of Medicine, University of the Philippines, 2000-2003.

BOOKS / MONOGRAPHS

Mojica-Henshaw MP. Cloning and Stem Cell Research In: Monograph on the Human Genome. 2004 Manila: National

Academy of Science and Technology.

Mojica MP, Bugna S. Contemporary Issues in STD-HIV/AIDS Research and Prevention: Focus on the Philippine Expe

rience. 2002 Manila: Ford Foundation.

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