Manager Project
Resume:
Constantin Radu
**-** ***** **, ******** Hill, NY 11418 Cell#: 718-***-****
Email: acdzsz@r.postjobfree.com
Profile
Experienced automation project & risk manager with interest in technology management and
organizational continuity, with a reputation for devising and implementing unique strategies to enhance
screening processes and business practices to achieve operational excellence. Ambitious creative problem
solver, recognized for eliminating chaos and reducing costs, driven by challenges and diversity. Excellent
leadership & strong project management skills.
Education
2014 – 2015 Grad Cert. in Risk Management & Continuity, Boston University, Boston, USA
2012 – 2014 M.Sc. in Project Management, Boston University, Boston, USA
2001 – 2002 Cert. in Database Development, Columbia University, New York, USA
1995 – 1999 B.Sc. in Chemistry, Hofstra University, Hempstead, USA
Professional Experiences
2004 – Present Laboratory Manager, Automation Specialist & Compound Manager
HTS Core Facility, Memorial Sloan Kettering Cancer Center, New York, USA
2002 – 2004 Senior Research Technician
Functional Proteomics, Memorial Sloan Kettering Cancer Center, New York, USA
1999 – 2002 Research Technician
Chemistry Core Facility, Memorial Sloan Kettering Cancer Center, New York, USA
Professional Accomplishments
• Analytical problem-solver, able to anticipate issues and create business solutions to assure business
continuity in a high pace environment while working individual scientists to address concerns and
improve efficiency.
• Led matrix teams of different backgrounds to complete projects without delay or incidents.
• Reduced inventory by 50% of all consumables / chemicals maintaining a stringent ordering process.
• Synergistic negotiator of service and consumable contracts.
• Reduced instrumental service coverage, reducing departmental cost from $500K to $250K.
• Developed a marketing plan to increase orders by working closely with bio imaging group to design
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flyers and increase awareness.
• Develop complex screening strategies to automate multiple projects simultaneously, thus saving time
and money for our customers.
• Established mission and business plan for newly created services within the department, providing
information, referrals and customer care to members.
• Involved in new technology evaluation & acquisition
• Managing the compound and RNAi libraries archival & retrieval group. Implemented new
automation & databases to assist compound and siRNA/shRNAs registration, plating & archiving.
• Supported and maintained robotics instruments and interfaces to work with scheduling software.
• Designed specific hardware components for several instruments to improve functionality and reduce
operational cost vs. outside vendor.
• Logistical coordinator for shipment / receiving (instruments / large RNAi libraries) while facilitating
with various departments within MSKCC.
• Facilitate interactive, hands-on training sessions for new hires / interns on instruments, safety and
institutional policies.
• As deputy fire warden with a C14 license, established and enforced chemical and radioactive safety
operations in the laboratory.
Software
• Proficient in MS Office, MS Project. Adobe Suite, Chem-Office, SciFinder
• Familiar with PL/SQL, Visio and Oracle 8i
Professional Activities
1. Reviewer: Journal of Laboratory Automation (2011-)
2. Judge: Student Poster, Society of Laboratory Automation and Screening (Feb 2013), Orlando, USA
3. Chair: Student Poster, Society of Laboratory Automation and Screening (Jan 2014), San Diego, USA
Professional Organizations
1. The Association for Laboratory Automation; Member (2006 - )
2. The Project Management Institute; Member (2012 - )
Invited Talks
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1. Spectroscopic Investigations of Heteroaromatic Chalcones: C. Radu, at "NCUR98 Conference",
April 23, 1998, Salisbury State University, MD, USA and Sponsored by Professor N. Wachter-
Jurcsak.
2. Reactions of 2-Pyridinecarboxaldehyde and 2-Quinolinecarboxaldehyde in Base-catalyzed Aldol
Reactions: C. Radu, at "46th Undergraduate Research Symposium", May 2, 1998, New York
University, NY, USA and Sponsored by Professor N. Wachter-Jurcsak.
3. Photochemical formation of 4’-N,N-Dimethylamino-3-Hydroxyflavone from 4-N,N-
Dimethylamino-2’-Hydroxychalcone: C. Radu, at “47th Undergraduate Research Symposium”, May
1, 1999, College of Mount St. Vincent, Riverdale, NY, USA and Sponsored by Professor T. Brack.
4. Assay Miniaturization into 1536 Well Microtiter Plates: The Memorial Sloan Kettering Cancer
Center Experience: C. Radu at “Lab Automation 2006”, January 24, 2006, Palm Springs, CA, USA
and Sponsored by Apricot Designs
5. The MSKCC Automation Experience: C. Radu, at "1st Annual 2012 Society for Laboratory
Automation & Screening", February 6, 2012, San Diego, CA, USA and Sponsored by Thermo Fisher
Scientific.
6. Design and Concept-Reliance of an Automated Platform: The Good, The Bad & The Ugly! : C.
Radu, at "LRIG MidAtlantic 20th Annual Technology Showcase", May 14, 2014, Somerset, NJ, USA
and Sponsored by LRIG.
Relevant Courses
• Project Management
• Project Risk and Cost Management
• Electronic Commerce, Systems and Web Design
• Accounting and Financial Analysis
• Business Continuity, Security & Risk Management
• International Business, Economics & Cultures
• Doing Business in North America
• The Innovation Process: Developing New Products & Services
• System-Wide Risk Planning, Strategy and Compliance
Publications
1. Wachter-Jurcsak N, Radu C, Redin K. “Addressing the Unusual Reactivity of 2-
Pyridinecarboxaldehyde and 2-Quinolinecarboxaldehyde in Base-catalyzed Aldol Reactions with
Acetophenone”. Tetrahedron Lett 1998(39):3903-3906
2. Brack, T, Radu C, Conti S, Wachter-Jurcsak N. “Photochemical formation of 4'-N,N-dimethylamino-
3-hydroxyflavone in hydrocarbon solutions of 4-N,N-dimethylamino- 2'-hydroxychalcone”.
Tetrahedron Lett. 1999(40):3995-3998
3. Ramajayam R, Giridhar R, Yadav MR, Djaballah H, Shum D, & Radu C “Synthesis and
antiproliferative activity of some diaryldiazepines and diarylpyrimidines” J Enzyme Inhib Med Chem 2007;
22:716-721.
4. Shum D, Radu C, Kim E, Cajuste M, Shao Y, Seshan VE, & Djaballah H “A generic assay utilizing
the Alamar Blue (resazurin) fluorescent dye for the detection of cytotoxic agents in chemical libraries
screened in 1536-well plate” J Enz Inhib Med Chem 2008; 23:931-45.
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5. Ramajayam R, Giridhar R, Yadav MR, Balaraman R, Djaballah H, Shum D, & Radu C “Synthesis,
antileukemic and antiplatelet activities of 2,3-diaryl-6,7-dihydro-5H-1,4-diazepines” Eur J Med Chem 2008;
43:2004-10.
6. Antczak, C, Radu, C, Djaballah, H “A Profiling Platform for the Identification of Selective
Metalloprotease Inhibitors” J Biomol Screen 2008; 13:285-294.
7. Antczak C, Shum D, Radu C, Seshan VE, Djaballah H “Development and Validation of a High-
density Fluorescence Polarization-based Assay for the Trypanosoma RNA Triphosphatase TbCet1” Comb
Chem High Thr Screen 2009; 12:258-68.
8. Antczak C, Kloepping C, Radu C, Genski T, Müller-Kuhrt L, Siems K, de Stanchina E, Abramson
DH, & Djaballah H “Revisiting Old Drugs as Novel Agents for Retinoblastoma: In vitro and In vivo
Antitumor Activity of Cardenolides” Invest Ophthalm Visual Science 2009; 50:3065-3073.
9. Shelton CC, Tian Y, Shum D, Radu C, Djaballah H, Li Y-M “A Miniaturized 1536-well format γ-
Secretase Assay” Assay Drug Dev Technol 2009; 7:461-70.
10. Antczak C, Takagi T, Ramirez CN, Radu C, & Djaballah H “Live Cell Imaging of Caspase
Activation for High Content Screening” J Biomol Screen 2009; 14:956-969.
11. Shum D, Smith JL, Hirsch AJ, Bhinder B, Radu C, Stein DA, Nelson JA, Früh K, & Djaballah H
“High-content assay to identify inhibitors of dengue virus infection” Assay Drug Dev Technol 2010; 8:553-
70.
12. Takagi T, Shum D, Parisi M, Santos RE, Radu C, Calder P, Rizvi Z, Frattini MG, & Djaballah H
“Comparison of Luminescence ADP Production Assay and Radiometric Scintillation Proximity Assay for
Cdc7 Kinase” Comb Chem High Through Screen 2011; 14:669-687.
13. Ibáñez G, Shum D, Blum G, Bhinder B, Radu C, Antczak C, Luo M, & Djaballah H “A High
Throughput Scintillation Proximity Imaging Assay for Protein Methyltransferases” Comb Chem High
Through Screen 2012; 15:359-371.
14. Shum D, Bhinder B, Radu C, Calder P, Ramirez CN, & Djaballah H “An Image-Based Biosensor
Assay Strategy to Screen for Modulators of the microRNA 21 Biogenesis Pathway” Comb Chem High
Through Screen 2012; 15:529-541.
15. Radu C, Adrar HS, Alamir A, Hatherley I, Trinh T, & Djaballah H “Designs and Concept-Reliance of
a Fully Automated High Content Screening Platform” J Lab Autom 2012; 17:359-369 .
16. Lee G, Ramirez CN, Kim H, Zeltner N, Liu B, Radu C, Bhinder B, Kim YJ, Choi IY, Mukherjee-
Clavin B, Djaballah H, Studer L “IKBKAP Expression Rescue in Neural Crest of Familial Dysautonomia-
iPSC Cells by Novel RT-PCR Based High Throughput Screening” Nature Biotech 2012; 30:1244-1248.
17. Shum D, Bhinder B, Ramirez, CN, Radu C, Calder PA, Beauchamp L, Magdaleno S, & Djaballah H
“An arrayed RNAi genome-wide screen identifies candidate genes involved in the miRNA 21 biogenesis
pathway” Assay Drug Dev Technol 2013; 11(3):191-205.
18. Bhinder B, Antczak C, Ramirez CN, Shum D, Radu C, Liu-Sullivan N, Frattini MG, Djaballah H
“An Arrayed Genome Scale Lentiviral Enabled shRNA Screen Identifies Lethal & Rescuer Gene Candidates”
Assay Drug Dev Technol 2013; 11(3):173-190.
19. Chau DM, Shum D, Radu C, Bhinder B, Gin D, Gilchrist ML, Djaballah H, Li YM "A Novel High-
Throughput 1536-well Notch1 γ-Secretase AlphaLISA Assay" Comb Chem High Through Screen 2013;
16:415-424.
20. Bhinder B, Antczak C, Shum D, Radu C, Mahida JP, Liu-Sullivan N, Ibáñez G, Somalinga B, Calder
PA, Djaballah H "Chemical & RNAi screening at MSKCC: a collaborative platform to discover &
repurpose drugs to fight disease" Comb Chem High Through Screen (in press)
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21. Antczak C, Boyoung W, Radu C, Bhinder B, Holland EC, Djaballah H "A High Content Assay
Strategy for the Identification and Profiling of ABCG2 Modulators in Live Cells" Assay Drug Dev
Technol (in press)
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