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Assistant Manager

Downingtown, PA
April 26, 2014

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Elyse Ellsworth

** ********** *****

Downingtown, PA 19335



• Thomas Jefferson University, Philadelphia, PA

August 2010-present

Research Technician/Lab Manager

o Ex vivo and in vivo pre-clinical testing of three anti-cancer drugs: performed

immunohistochemistry including antibody optimization and TUNEL experiments on prostate

organ cultures and xenograft tumors of human prostate cancer cells, refining and improving the

original protocols; analyzing the results to quantify the data; and photographing the stained


o Developed a method to quantify lung metastasis in in vivo prostate cancer

experiments and conducted out analysis to determine the role of Stat5 proteins in prostate cancer


o Histology experience: embedding, sectioning, and H&E staining of hundreds

of tissue samples including tumor, skin, liver, lung, kidney, breast, and brain; experience in

manual and automated staining procedures

o Breast cancer tumor line development: characterization of four tumor lines,

with a focus on micrometastasis rates; analysis of micrometastasis by visual examination of lung

and liver of the mouse host, and via rtPCR/electrophoresis

o Supervisor and thesis committee member of a Masters student completing a

clerkship: instructed and guided student in performing immunohistochemistry research projects

that formed the basis of the student’s thesis

o Developed protocols for submission to IACUC for in vitro experiments in

mouse models

o Daily maintenance of lab, including ordering, maintaining financial records,

lab meeting coordination, ensuring compliance with safety regulations, and maintenance of

supplies and equipment

o Proficient in Microsoft programs: Word, Excel, Access; Proficient in Adobe

programs: Photoshop, Acrobat Professional, Illustrator; experience using Filemaker

• Medical Genetics Colony, University of Pennsylvania, Philadelphia, PA

September 2009-

Veterinary Student Assistant January 2010

o Supported research in gene therapy by performing physical exams of and administering

treatments and vaccinations to dozens of cats in the Medical Genetics cat colony twice a day


o Treatments given included administering medications, palpation, administering subcutaneous

fluids, and tube feeding

• The Pennsylvania State University, University Park, PA September 2007-

Undergraduate Research Assistant April 2009

o Developed a research project entitled The Role of GDF-15 in Erythroid Short-Term

Radioprotection to determine the role of the gene GDF-15 in stress erythropoesis and in

relation to the BMP4 and Hedgehog genes, on which my honors thesis was based

o Performed gel electrophoresis, PCR, flow cytometry, and bone marrow transplant in carrying

out research on a mouse model

• Hickory Veterinary Hospital, Plymouth Meeting, PA

Veterinary Technician/Assistant- Summer Employee May 2007- August 2008

o Assisted veterinarians in a 15-doctor practice with such tasks as obtaining

patient history, restraining animals, drawing blood, dispensing medications, and taking


o Called owners to answer questions and explain bloodwork results, and wrote

follow-up letters to referring veterinarians

o Cared for hospitalized patients by providing food/water, cleaning cages,

administering medications, obtaining vital signs, and running bloodwork


Lehigh University; Bethlehem, PA Expected completion: May 2015

Master of Science in Molecular Biology

The Pennsylvania State University; University Park, PA May 2009

The Schreyer Honors College

Bachelor of Science in Animal Bioscience with a Spanish minor

Honors in Animal Bioscience, G.P.A.: 3.46/4.00

University of Pennsylvania; Philadelphia, PA

School of Veterinary Medicine


Haddad BR, Gu L, Mirtti T, Dagvadorj A, Vogiatzi P, Hoang DT, Bajaj R, Leiby B, Ellsworth E,

Blackmon S, Ruiz C, Curtis M, Fortina P, Ertel A, Liu C, Rui H, Visakorpi T, Bubendorf L,

Lallas CD, Trabulsi EJ, McCue P, Gomella L, Nevalainen MT. STAT5A/B Gene Locus

Undergoes Amplification During Human Prostate Cancer Progression. American Journal of

Pathology, 182:2264-2275, 2013.

Gu L, Liao Z, Hoang DT, Dagvadorj A, Gupta S, Blackmon S, Ellsworth E, Talati P, Leiby B, Zinda M,

Lallas CD, Trabulsi EJ, McCue P, Gomella L, Huszar D, Nevalainen MT. Pharmacologic

Inhibition of Jak2-Stat5 Signaling by Jak2 inhibitor AZD1480 Potently Suppresses Growth of

Both Primary and Castrate-Resistant Prostate Cancer. Clinical Cancer Research, 19:5658-5674,



• Shelter Medicine Club Officer, The University of Pennsylvania September 2009- January 2010

o Foster Care Co-Coordinator: provide support to students fostering kittens through Philadelphia

Animal Welfare Society (PAWS), ensuring that students have preventative medications as well

as transporting kittens to and from students’ homes to be sterilized, enabling PAWS to care for

a greater number of cats

o Volunteer for PAWS by sedating and castrating cats, and preparing cats for spays as well as

vaccinating and microchipping cats

o Assisted in organizing and carrying out fundraisers, which raising several hundred dollars for

the club

• Orientation Mentor, The Pennsylvania State University June- September 2006

o Provided support to incoming students in the Schreyer Honors College by

sharing my experience and advice as they prepared for college

o Lead students in various activities to help familiarize them with the college

and to introduce them to their fellow students


• Schreyer Honors College 2005-2009

• College of Agricultural Sciences Scholarships 2005-2009

• Academic Excellence Scholarship 2005-2009

• Dean’s List Fall 2005, Fall 2006,

Spring 2008, Spring 2009

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