Assistant Manager
Resume:
Elyse Ellsworth
Downingtown, PA 19335
*********@*****.***
WORK EXPERIENCE
• Thomas Jefferson University, Philadelphia, PA
August 2010-present
Research Technician/Lab Manager
o Ex vivo and in vivo pre-clinical testing of three anti-cancer drugs: performed
immunohistochemistry including antibody optimization and TUNEL experiments on prostate
organ cultures and xenograft tumors of human prostate cancer cells, refining and improving the
original protocols; analyzing the results to quantify the data; and photographing the stained
slides
o Developed a method to quantify lung metastasis in in vivo prostate cancer
experiments and conducted out analysis to determine the role of Stat5 proteins in prostate cancer
metastasis
o Histology experience: embedding, sectioning, and H&E staining of hundreds
of tissue samples including tumor, skin, liver, lung, kidney, breast, and brain; experience in
manual and automated staining procedures
o Breast cancer tumor line development: characterization of four tumor lines,
with a focus on micrometastasis rates; analysis of micrometastasis by visual examination of lung
and liver of the mouse host, and via rtPCR/electrophoresis
o Supervisor and thesis committee member of a Masters student completing a
clerkship: instructed and guided student in performing immunohistochemistry research projects
that formed the basis of the student’s thesis
o Developed protocols for submission to IACUC for in vitro experiments in
mouse models
o Daily maintenance of lab, including ordering, maintaining financial records,
lab meeting coordination, ensuring compliance with safety regulations, and maintenance of
supplies and equipment
o Proficient in Microsoft programs: Word, Excel, Access; Proficient in Adobe
programs: Photoshop, Acrobat Professional, Illustrator; experience using Filemaker
• Medical Genetics Colony, University of Pennsylvania, Philadelphia, PA
September 2009-
Veterinary Student Assistant January 2010
o Supported research in gene therapy by performing physical exams of and administering
treatments and vaccinations to dozens of cats in the Medical Genetics cat colony twice a day
weekly
o Treatments given included administering medications, palpation, administering subcutaneous
fluids, and tube feeding
• The Pennsylvania State University, University Park, PA September 2007-
Undergraduate Research Assistant April 2009
o Developed a research project entitled The Role of GDF-15 in Erythroid Short-Term
Radioprotection to determine the role of the gene GDF-15 in stress erythropoesis and in
relation to the BMP4 and Hedgehog genes, on which my honors thesis was based
o Performed gel electrophoresis, PCR, flow cytometry, and bone marrow transplant in carrying
out research on a mouse model
• Hickory Veterinary Hospital, Plymouth Meeting, PA
Veterinary Technician/Assistant- Summer Employee May 2007- August 2008
o Assisted veterinarians in a 15-doctor practice with such tasks as obtaining
patient history, restraining animals, drawing blood, dispensing medications, and taking
radiographs
o Called owners to answer questions and explain bloodwork results, and wrote
follow-up letters to referring veterinarians
o Cared for hospitalized patients by providing food/water, cleaning cages,
administering medications, obtaining vital signs, and running bloodwork
EDUCATION
Lehigh University; Bethlehem, PA Expected completion: May 2015
Master of Science in Molecular Biology
The Pennsylvania State University; University Park, PA May 2009
The Schreyer Honors College
Bachelor of Science in Animal Bioscience with a Spanish minor
Honors in Animal Bioscience, G.P.A.: 3.46/4.00
University of Pennsylvania; Philadelphia, PA
School of Veterinary Medicine
PUBLICATIONS
Haddad BR, Gu L, Mirtti T, Dagvadorj A, Vogiatzi P, Hoang DT, Bajaj R, Leiby B, Ellsworth E,
Blackmon S, Ruiz C, Curtis M, Fortina P, Ertel A, Liu C, Rui H, Visakorpi T, Bubendorf L,
Lallas CD, Trabulsi EJ, McCue P, Gomella L, Nevalainen MT. STAT5A/B Gene Locus
Undergoes Amplification During Human Prostate Cancer Progression. American Journal of
Pathology, 182:2264-2275, 2013.
Gu L, Liao Z, Hoang DT, Dagvadorj A, Gupta S, Blackmon S, Ellsworth E, Talati P, Leiby B, Zinda M,
Lallas CD, Trabulsi EJ, McCue P, Gomella L, Huszar D, Nevalainen MT. Pharmacologic
Inhibition of Jak2-Stat5 Signaling by Jak2 inhibitor AZD1480 Potently Suppresses Growth of
Both Primary and Castrate-Resistant Prostate Cancer. Clinical Cancer Research, 19:5658-5674,
2013.
LEADERSHIP AND SERVICE
• Shelter Medicine Club Officer, The University of Pennsylvania September 2009- January 2010
o Foster Care Co-Coordinator: provide support to students fostering kittens through Philadelphia
Animal Welfare Society (PAWS), ensuring that students have preventative medications as well
as transporting kittens to and from students’ homes to be sterilized, enabling PAWS to care for
a greater number of cats
o Volunteer for PAWS by sedating and castrating cats, and preparing cats for spays as well as
vaccinating and microchipping cats
o Assisted in organizing and carrying out fundraisers, which raising several hundred dollars for
the club
• Orientation Mentor, The Pennsylvania State University June- September 2006
o Provided support to incoming students in the Schreyer Honors College by
sharing my experience and advice as they prepared for college
o Lead students in various activities to help familiarize them with the college
and to introduce them to their fellow students
HONORS/AWARDS
• Schreyer Honors College 2005-2009
• College of Agricultural Sciences Scholarships 2005-2009
• Academic Excellence Scholarship 2005-2009
• Dean’s List Fall 2005, Fall 2006,
Spring 2008, Spring 2009
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