Manager Experience
Resume:
Julia Schauer
Coatesville, Pennsylvania
19320
Insightful, results-driven pharmaceutical / biotech laboratory professional with proven
success directing and conducting a broad range of protein purification and
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characterization techniques is seeking a challenging position in research and/or
product development.
Qualifications
Excel at managing complex projects, understanding advanced scientific concepts and
conducting sound experiments to synthesize new information. Effective manager of
time and resources. Sixteen years of extensive laboratory experience in monoclonal
antibody modification, purification and characterization, protein and peptide chemistry,
molecular biology and biochemical techniques, cell culture, in-vitro and in-vivo study
design and analysis, organic synthetic chemistry, analytical chemistry, radiochemistry,
plasmid DNA complex formation, assay development, formulations, and laboratory
safety in a cGMP environment. My experience also includes laboratory- based data
generation and interpretation, coordination of in-house and outside collaborations,
technical group presentations, patent support, written reports, and publication of
manuscripts in several professional journals.
“Julia has demonstrated herself to be an excellent communicator and to have the
ability to effectively supervise situations and personnel in a matrix structure. We need
more employees like this.”
Dr. Richard Carrano, Vice President, Technology Devmt. and Regulatory Affairs
1994 Performance Review Excerpt, Apollon, Inc.
Work Experience
Self Employed Artist
8/2008 - present
Educator: Chemistry and Physics
8/2002 - 8/2008 Downingtown Area School District, Downingtown, PA
Senior Research Scientist
11/1992 - 8/2000 Wyeth Ayerst Research (formerly Apollon, Inc.), Malvern, PA
Prepared and purified modified proteins, antibodies, and antibody fragments. As the
point person in collaboration with the Molecular Hepatology Dept. of Harvard Medical
School, I prepared conjugated IgG antibodies utilizing my own bifunctional ligands.
The resulting antibody conjugates were complexed with DNA and tested for receptor
targeted cellular uptake in-vitro.
Promoted to lead the DNA-based vaccine delivery program. Invented and
developed novel strategies to transfect cells with plasmid DNA. Collaborated with
medical, scientific and legal professionals, including M.D.'s, Ph.D.'s and patent
attorneys. Identified goals and priorities in support of deadline-driven objectives.
Directed junior staff, executed and documented research experiments, and reported
results in technical group presentations and in published peer-reviewed manuscripts.
Conducted cell culture experiments utilizing sterile technique to screen product
candidates for efficacy in-vitro. Independently optimized the assay and identified the
lead compound.
Conducted the total synthesis of a variety of molecules including carbohydrates,
steroids, peptides, polyamines, chelating agents, modified proteins, and receptor
targeted DNA transfection agents.
Prepared and utilized radioactive probes for elucidating DNA complexation
mechanisms.
Conducted stability studies and physico-chemical characterization of DNA
complexes including dynamic light scattering, zeta potential determination, and sizing
by flow cytometry.
Senior Research Associate
6/1987 - 11/1992 Centocor, Inc., Malvern, PA
Developed and optimized purification and characterization methods for radio-labeled
monoclonal antibodies and antibody fragments, and also for complex organic
compounds. Conducted biochemical analyses (SDS-PAGE, Size Exclusion HPLC,
and IEF) of monoclonal antibodies. Conducted biochemical analyses (ELISA,
Western blots, RIA) of both human patient (blood serum) and laboratory samples to
evaluate efficacy of various monoclonal antibody based drug products. Prepared and
tested radioactive imaging agents as new diagnostic products for cancer and heart
disease. Supervised scale up preparation of a new product for use in several human
clinical trials.
Junior Research Chemist
7/1984 - 8/1986 Johnson Matthey, Inc., West Chester, PA
Synthesized organic molecules to attach platinum to monoclonal antibodies as new
chemotherapeutic drugs.
Education
8/2000 - 5/2002 West Chester University/ M. Ed. Chemistry, West Chester, PA
Master's Degree
Cumulative GPA: 3.9 / 4.0
1/1981 - 5/1984 West Chester University/ B.S. Chemistry, West Chester, PA
Bachelor's Degree
Cumulative GPA: 3.8 / 4.0, Summa cum Laude Honors graduate.
Skills
Cell and molecular biology techniques and assay development, HPLC, FTIR, UV-Vis,
SDS-Page electrophoresis, particle size analysis, gel filtration, radio-immuno and
ELISA assay development, elemental analysis, mass spectrometry, gas
chromatography, atomic absorption, NMR, sterile technique, formulations, protein
purification, thin layer chromatography, GLP and GMP, laboratory safety, MS Office
(Word, Excel, PowerPoint, etc.), excellent verbal and written communication skills.
Additional Information
Six years of additional experience as a professional science educator have advanced
my interpersonal, time management and presentation skills. I work well with individuals
of diverse backgrounds, and maintain a professional demeanor in stressful situations.
References available upon request
Contact this candidate