Manager Quality Control
Resume:
Ricardo Salomon Moraes
Status: U.S. Citizen
*********@*****.***
HU UH
PROFESSIONAL SKILLS
0B
Medical Technologist (MT)/Medical Laboratory (MLS)/Molecular Biology (MB)
Scientist by the American Society of Clinical Pathologist (ASCP) eligible
Laboratory Supervision and Management including lab compliance with
Environmental Health and Safety, Radiation Safety, and HIPPA
Organized and goal-oriented with more than 12 years’ experience in laboratory
management
Skilled in building excellent rapport with laboratory members, core facilities,
departments, and potential clients for our services
Very experienced in animal surgery, implanting and transplant mouse tissue and
primary human tumors in immune-deficient mice
Over 20 years’ experience in histology, pathology, and immunohistochemistry
techniques
Broad knowledge of cell culture techniques, cell-based assays, fluorescence
microscopy, image analysis, and flow cytometry
Experience with in cells transfection, electroporation or viral infection (lentiviruses,
retroviruses, adenoviruses and baculoviruses), including experiments with human -
derived cells and tissues
Molecular Biology techniques, such as DNA & RNA preparation, PCR, DNA
cloning, protein synthesis, electrophoresis, cloning, Southern, Northern and
Western blotting and analysis
Writing, editing and publishing papers and grant applications (please see awards,
grants and publications)
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PROFESSIONAL EXPERIENCE
Quality Control Supervisor – Cell Therapy Lab Cord Blood Bank
Present
Department Stem Cell Therapy
MD Anderson Cancer Center, Houston, Texas
Responsible and accountable for day to day technical, operational, and personal
management of the Cord Blood Bank Quality Assurance/Quality Control Laboratory.
Manage the Cord Blood Bank Quality Assurance/Quality Control Laboratory, including quality contr ol
testing, flow cytometry, tissue culture, environmental monitoring, equipment, product discard and
validation.
Manage quality control staff performance, ensuring all approved policies and procedures are implemented
and adhered to by the staff.
Ensured proper documentation and/or deviations.
Implement and maintain current knowledge of technical procedures, policies, regulations, and standards
such as FDA’s GLP, GMP, GTP
Review records and approve data
Responsible for writing and review technical standard o perational procedures and policies. Review SOPs
written by other staff.
Commonly used techniques: Flow cytometry, cell culture, colony formation assay.
2011-2013 Research Investigator
Department of Experimental Therapeutics
MD Anderson Cancer Center, Houston, Texas
Project: Establish and Profiling New Models of Inflammatory Breast Cancer and Cancer
Stem Cells
Team leader to conduct laboratory research to establish new models of Inflammatory Breast Cancer (IBC)
Oversee, organize, and schedule animal surgery, transplantation, collection and analyses of tumor samples
Successful in establishing four new IBC lines
Conduct and design experiments to help the characterization of new IBC lines using cell culture, molecular
biology (DNA, RNA, and protein), and genomic platforms’
Prepare figures for publication
Present data at national meetings
Commonly used techniques: animal surgery and doses animals (via oral, intravenous, intradermal,
intraperitoneal or subcutaneous routes), animal image (X-ray, luciferase), nucleic acid isolation
(DNA, RNA, Protein) and quantitation, Southern, Northern and Western blotting and analysis,
cloning, transfection, electroporation and viral infection (lentiviruses, retroviruses, adenoviruses
and baculoviruses), cell culture, mammospheres culture, histology, immunohistochemistry,
immunofluorescence, microscopy (Phase contrast, Confocal, Deconvolution, Multiphoton).
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2002-2011 Senior Research Associate
The Breast Cancer Center
Baylor College of Medicine
Project: Hedgehog Network Mutations as Mouse Models for Early and Invasive Breast
Cancer
Lab manager responsible for the day-to-day operations
Oversee implementation and compliance with Environmental Health and Safety, Radiation Safety, and
HIPPA
Maintain and schedule equipment services
Oversee, organize, and schedule animal surgery, transplantation, collection and analyses of tumor sampl es
Supervise and train staff, students, and post-docs on a variety of molecular biology and cell culture
Point person to setup collaboration and scheduling experiments in vivo
Team leader responsible to setup and generate new transgenic mice strains
Supervise animal colony
Design, conduct, and analyze experiments
Review, analyze, and summarize data for presentation in national and international meetings
Prepare, write and submit papers and grants
Commonly used techniques: animal surgery and doses animals (via oral, intravenous, intradermal,
intraperitoneal or subcutaneous routes), animal image (X-ray, luciferase), histology,
immunohistochemistry, immunofluorescence, nucleic acid isolation (DNA, RNA, Protein) and
quantitation, Southern, Northern and Western blotting and analysis cloning, transfection,
electroporation and viral infection (lentiviruses, retroviruses, and adenoviruses), cell culture,
mammospheres culture, microscopy (Phase contrast, Confocal, Deconvolution, Multiphoton) .
2008-2011 Q-PCR Core Manager
The Breast Cancer Center
Baylor College of Medicine, Houston, Texas
Coordinate and manage the core lab, including calculate and prepare the budget
Estimate operational cost for the core
Maintain and schedule equipment services
Design, conduct and analyze experiments
Organize and supervise the use of equipment
Offer training and support for users
Oversee implementation and compliance with Environmental Health and Safety, and HIPPA
Commonly used techniques: nucleic acid isolation and quantitation, cloning, PCR, RT-PCR, Q-PCR
3
2000 - 2002 Postdoctoral Research Associate and Consultant (per equivalence)
U
Department Communication Cellulaire et Différenciation
French Institute for Agronomy Research (INRA)
Project: Regulation of the food intake: search for new leptin target genes.
Team leader responsible to setup and generate new Diet Induced Obesity mice model
Design, conduct, and review experiments
Analyze, and summarize data for presentation in national and international meetings
Point person to setup collaboration and scheduling experiments in vivo
Supervise animal colony
Prepare, write and submit papers
Commonly used techniques: animal surgery and doses animals (via oral, intravenous, intradermal,
intraperitoneal or subcutaneous routes), animal image (X-ray), nucleic acid isolation (DNA, RNA,
Protein) and quantitation, Southern, Northern and Western blotting and analysis cloning,
transfection, electroporation and viral infection (lentiviruses, retroviruses, and adenoviruses), cell
culture, histology, immunohistochemistry, immunofluorescence, microscopy ( Phase contrast,
Confocal).
1996 - 2000 Research Associate
U
Department of Molecular and Cellular Biology
Baylor College of Medicine
Project: Hormone-induced refractoriness to mammary carcinogenesis.
Project: Selenium inhibition of mammary cancer: A mechanism approach.
Project: Biology of the Mouse Mammary Preneoplasia
Project: p19ARF and p27kip1 in Mammary Cell Differentiation and Immortalization.
Lab manager responsible for the day-to-day operations
Oversee implementation and compliance with Environmental Health and Safety, Radiation Safety, and
HIPPA
Maintain and schedule equipment services
Supervise and train students and post-docs on a variety of molecular biology and cell cultu re
Design, conduct, and review experiments
Analyze, and summarize data for presentation in national and international meetings
Oversee, organize, and schedule animal surgery, transplantation, collection and analyses of tumor samples
Point person to setup collaboration and scheduling experiments in vivo
Supervise animal colony
Prepare, write and submit papers
Commonly used techniques: animal surgery and doses animals (via oral, intravenous, intradermal,
intraperitoneal or subcutaneous routes), nucleic acid isolation (DNA, RNA, Protein) and
quantitation, Southern, Northern and Western blotting and analysis, cloning, transfection,
electroporation and viral infection (lentiviruses, retroviruses, and adenoviruses), cell culture, animal
image (X-ray, luciferase), histology, immunohistochemistry, immunofluorescence, microscopy
(Phase contrast, Confocal, Deconvolution).
4
1994 - 1996 Research Assistant
U
Laboratory of Cell Biology and Pathology
Department of Pathology
Thomas Jefferson University, Philadelphia, PA.
Project: Epithelial Growth Factor and immortalization of breast epithelial cells in
transgenic mice
Lab manager responsible for the day-to-day operations
Maintain and schedule equipment services
Supervise and train staff, students, and post-docs on a variety of molecular biology and cell culture
Design, conduct, and review experiments
Oversee, organize, and schedule animal surgery, transplantation, collection and analyses of tumor samples
Point person to setup collaboration and scheduling experiments in viv o
Supervise animal colony
Commonly used techniques: animal surgery and doses animals (via oral, intravenous, intradermal,
intraperitoneal or subcutaneous routes), animal image (X-ray), nucleic acid isolation (DNA, RNA,
Protein) and quantitation, Southern, Northern and Western blotting and analysis cloning,
transfection, electroporation and viral infection (lentiviruses, retroviruses, and adenoviruses), cell
culture, histology, immunohistochemistry, immunofluorescence, microscopy ( Phase contrast,
Confocal).
1992 - 1994 Research Assistant and consultant
Laboratory of Molecular Biology
Department of Pathology
Fox Chase Cancer Center, Philadelphia, PA
Project: Role of pregnancy against mammary carcinogenesis.
Project: Immortalization and transformation of human breast epithelial cell line MCF 10F
treated with chemical carcinogens.
Lab manager responsible for the day-to-day operations
Maintain and schedule equipment services
Supervise and train staff, students, and post-docs in animal surgery
Design, conduct, and review experiments
Oversee, organize, and schedule animal surgery, transplantation, collection and analyses of tumor samples
Point person to setup collaboration and scheduling experiments in vivo
Supervise animal colony
Commonly used techniques: animal surgery and doses animals (via oral, intravenous, intradermal,
intraperitoneal or subcutaneous routes), nucleic acid isolation (DNA, RNA, Protein) and
quantitation, Southern, Northern and Western blotting and analysis, cloning, transfection,
electroporation and viral infection (lentiviruses, retroviruses, and adenoviruses), cell culture,
histology, immunohistochemistry, immunofluorescence, microscopy ( Phase contrast, Confocal)
5
1990 - 1992 Research Assistant
U
Biochemistry Research Laboratory of the Women Hospital of
UNICAMP - Campinas - Brazil.
Commonly used techniques: nucleic acid isolation, mitochondria isolation, biochemical analysis,
cellular and mitochondrial respiration
1987 - 1990 Laboratory Supervisor
U
Laboratory of Cytology and Embryology
Catholic University of Campinas - Brazil.
Lab manager responsible for the day-to-day operations
Maintain and schedule equipment services
Supervise and train staff, and students in animal surgery
1985 - 1987 Research Technician
U
Laboratory of Cytology and Embryology
Catholic University of Campinas - Brazil.
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EDUCATION
2000-2002 Master of Science (DEA): Biochemistry
U
Equivalence – Université Claude Bernard, Lyon, France, September 2000
1985-1988 Bachelor of Science - Biology Sciences
Catholic University of Campinas (PUCCamp) - Brazil.
EDUCATION EXPERIENCE
1990-1992 Assistant Professor of Cytology and Embryology
Catholic University of Campinas – Brazil
1991-1992 Teacher of Biology at Objetivo High School
Campinas, Brazil.
1989-1991 Teacher of Biology at Integral High School
Campinas, Brazil.
1987-1990 Instructor of Cytology
Catholic University of Campinas – Brazil
AWARDS and GRANTS
2000-2002 Diet induced obesity (DIO) and leptin treatment as a model for obesity study.
P.I.: Martine Begeot, Ph.D.
Role: Postdoctoral Research Associate
French Institute for Agronomy Research, Lyon, France
1999-2002 Selenium inhibition of mammary cancer: A mechanism approach.
P.I.: Raghu Sinha, Ph.D.
Role: Research Assistant and Consultant
United States of America - Department of Defense – Mammary Gland Project
1991-1992 National Brazilian Council graduation fellowship.
1989-1992 National Brazilian Council research training fellowship.
PROFESSIONAL MEMBERSHIP
American Association for Cancer Research - #259018
American Association for the Advancement of Science - #05073960
Brazilian Council of Biology – CRB-1 #10331-01
7B
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PUBLICATIONS - BOOK
Julien Tirard, Ricardo Moraes, Danielle Naville, and Martine Begeot. Microarray Analysis of
U
Alterations Induced by Obesity in White Adipose Tissue Gene Expression Profiling. In: U
Genomics in Endocrinology: DNA Microarray Analysis in Endocrine Health and Disease
Series: Contemporary Endocrinology (ed. Handwerger, Stuart; Aronow, Bruce). New Jersey
HU UH
(USA): Humana Press, 2008. ISBN: 978-1-58829-651-1
PUBLICATIONS – JOURNAL ARTICLES
Robertson FM, Chu K, Boley KM, Ye Z, Liu H, Wright MC, Bagsby AL, Moraes R, Zhang X,
Green TL, Barsky SH, Heise C and Cristofanilli M. The Class I HDAC Inhibitor Romidepsin
Targets Inflammatory Breast Cancer Tumor Emboli and Lymphangiogenesis. Mol. Cancer Ther.
in review.
Robertson FM, Liu H, Chu K, Ochoa AE, Moraes R, Zhang X, Boley KB, Ye Z, Wright MC,
Barsky SH, and Cristofanilli M. Anaplastic Lymphoma Kinase Induces Formation of Tumor
Emboli with Encircling Lymphatic Vessels and an Interleukin-17 Driven Pro-Inflammatory
Cytokine Signature. Oncogene. in review.
Robertson FM, Petricoin EF, Chu K, Fernandez SV, Mu Z, Alpaugh RK, Pei J, Circo R,
Wulfkuhle J, Boley KM, Liu H, Ye Z, Wright MC, Zhang X, Moraes R, Jin J, Wu H, Zook M,
Yu M, DeMaria R, Barsky SH and Cristofanilli M. Therapeutic implications of ALK signaling
pathway activation and increased ALK copy number in Inflammatory Breast Cancer. Cancer
Discovery, in review.
John D. Landua, Ricardo C. Moraes, Ellen M. Carpenter, Heidi Weiss, Margaret Neville, and
Michael T. Lewis. Loco-regional Failure of STAT5 Phosphorylation and Impaired Lactation in
Hoxd10 and Hoxd9/Hoxd10 Null Mice. Submitted, 2013.
Chu K, Boley KM, Moraes R, Barsky SH, Robertson FM. The paradox of E-cadherin: role in
response to hypoxia in the tumor microenvironment and regulation of energy metabolism.
Oncotarget. Mar; 4 (3):446-62, 2013
Robertson FM, Chu K, Fernandez S, Mu, Z, Zhang X, Liu H, Boley KM, Alpaugh RK, Ye Z,
Wright MC, Luo A, Moraes R, Wu H, Zook M, Barsky SH and Cristofanilli M. Genomic
profiling of pre-clinical models of inflammatory breast cancer identifies a signature of
mesenchymal-epithelial plasticity and suppression of TGFb signaling. J Clin Exp Pathol 2:119,
2012.
Hong Chang, Qing Li, Ricardo C. Moraes, Michael T. Lewis, and Paul A. Hamel. Activation of
Erk by Sonic Hedgehog Independent of Canonical Hedgehog Signaling. The International
Journal of Biochemistry & Cell Biology, 2010; 42: 1462–1471.
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PUBLICATIONS (cont.)
Ricardo C. Moraes, Hong Chang, Nikesha Harrington, John Landua, Jonathan Prigge, Timothy
Lane, Brandon Wainright, Paul A. Hamel, and Michael T. Lewis. Ptch 1 Is Required Locally for
U
Mammary Gland Morphogenesis and Systemically for Ductal Elongation. Development, 2009,
U
136: 1423-32.
Bingnan Gu, Peng Sun, Yuanyang Yuan, Ricardo C. Moraes, Aihua Li Andy Teng, Anshu
Agrawal, Catherine Rhéaume, Virginia Bilanchone, Jacqueline M. Veltmaat, Ken-Ichi
Takemaru, Sarah Millar, Eva Y-H. P. Lee, Michael T. Lewis, Boan Li, and Xing Dai. Pygo2 U
expands mammary progenitor cells by facilitating histone H3 K4 methylation. Journal of Cell
U
Biology, 2009, 185 (5): 811-826.
Xiaomei Zhang, Nikesha Harrington, Ricardo C. Moraes, Meng-Fen Wu, Susan G. Hilsenbeck,
and Michael T. Lewis. Cyclopamine Inhibition of Human Breast Cancer Cell Growth
U
Independent of Smoothened (Smo). Breast Cancer Research and Treatment, 2009, 115(3): 505-
U
21.
Ricardo C. Moraes, Xiaomei Zhang, Nikesha Harrington, Jennifer Y. Fung, Meng-Fen Wu,
Susan G. Hilsenbeck, D. Craig Allred, and Michael T. Lewis. Hedgehog Signaling is Altered
U
Frequently In Human Breast Cancer and Constitutive Activation of Smoothened (Smo) Leads To
Increased Proliferation and Ductal Dysplasia In Mammary Glands of Transgenic Mice. U
Development, 2007, 134: 1231-1242.
Zhijun Du, Katrina Podsypanina, Shixia Huang, Amanda McGrath, Michael J. Toneff, Ekaterina
Bogoslovskaia, Xiaomei Zhang, Ricardo C. Moraes, Michele Fluck, D. Craig Allred, Michael
T. Lewis, Harold E. Varmus, Yi Li. Introduction of oncogenes into mammary glands in vivo with
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an avian retroviral vector initiates and promotes carcinogenesis in mouse models. PNAS, 2006,
U
103: 173**-*****.
Martin A, de Vittoris R, David V, Moraes R, Begeot M, Lafage-Proust MH, Alexandre C, Vico
L, Thomas T. Leptin modulates both resorption and formation while preventing disuse-induced
U
bone loss in tail-suspended female rats. Endocrinology. 2005 Aug; 146(8):3652-9.
U
Moraes, R. C.; Blondet, A.; Birkenkamp-Demtroder, F.; Orntoft, T. F.; Gertler, A.; Durand, P.;
Naville, D.; Bégeot, M. Study of the alteration of gene expression in adipose tissue of diet-
U
induced obesity (DIO) mice by RT-PCR and microarray analyses. Endocrinology, 2003 Nov;
U
144(11):4773-82.
Kong, G.; Chua, S. S., Yijun, Y.; Kittrell, F.; Moraes, R. C.; Medina, D.; Said, T. K. Functional
U
analysis of cyclin D2 and p27(Kip1) in cyclin D2 transgenic mouse mammary gland during
development. Oncogene. Oct 17; 21(47):7214-25, 2002.
U
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PUBLICATIONS (cont.)
Medina, D.; Peterson, L. E.; Moraes, R.; Gay, J. Short-term exposure to estrogen and
U
progesterone induces partial protection against N-nitroso-N-methylurea-induced mammary
tumorigenesis in Wistar-Furth rats. Cancer Lett, 169 (1): 1-6, 2001.
U
Said, T.; Moraes, R.C.B.; Singh, U.; Kittrell, F. S.; Medina, D. Cyclin-dependent kinase (cdk)
U
inhibitors/cdk4/cdk2 complexes in early stages of mouse mammary preneoplasia. Cell Growth
U
and Differentiation, 12(6): 285-295, 2001.
Said, T.; Moraes, R.C.B.; Sinha, R.; Medina, D. Mechanisms of Suberoylanilide Hydroxamic
U
Acid Inhibition of Mammary Cell Growth. Brest Cancer Res., 3: 122-133, 2001.
U
Sinha, R.; Kiley, S. C.; Lu, J.X.; Moraes, R.C.B.; Thompson, H. J; Jaken, S.; Medina, D. Effects
U
of methylselenocyctein on PKC activity, cdk2 phosphorylation and gadd gene expression in
synchronized mouse mammary epithelial tumor cells. Cancer Letters, 146: 135-145, 1999.
U
Barnabas-Soho, N.; Moraes, R.C.B.; Calaf, G.; Estrada, S. and Russo, J. Role of p53 in MCF-
U
10F cell immortalization and chemically-induced neoplastic transformation. International
U
Journal of Oncology, 7:1289-1296, 1995.
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ABSTRACTS
Ricardo C. Moraes, John Landua, and Michael T. Lewis. Patched-1 is required locally and
systemically for mammary gland morphogenesis and ductal elongation. 2009 AACR Annual
Meeting, Denver, CO. April 18 - 22, 2009.
Xiaomei Zhang, Jian Huang, Qing Lai, Xiaoxian Li, Ricardo C. Moraes, Helen Wong, Lisa
Wiechmann, Rachel Schiff, Massimo Cristofanilli, Savitri Krishnamurthy, James M. Reuben,
Wendy A. Woodward, Jenny C. Chang, Michael T. Lewis. Efficient generation of primary
xenografts using normal and malignant human mammary epithelium in SCID/Beige mice without
humanizing fibroblasts. 2009 AACR Annual Meeting, Denver, CO. April 18 - 22, 2009.
Ricardo C. Moraes, John Landua, and Michael T. Lewis. Unmasking stem/progenitor cell
U
properties using short-term transplantation. Department of Defense (DOD) Breast Cancer
U
Research Program (BCRP) 5th Era of Hope 2008 Meeting. Baltimore, Maryland, on June 25–28,
2008.
Moraes RC, Tierney M, Harrington N, Landua J, Goodell M and Lewis MT
The Mesenchymal Dysplasia Allele of Patched-1 (Pthc1mes) is a Pleitropoic Mutation Affecting
U
Embryonic and Postnatal Mammary Gland Development. 5th Annual Center Symposium, Texas,
U
USA, November 2007.
Moraes RC, Zhang X, Harrington N, Fung JY, Wu M-F, Hilsenbeck SG, Allred C, Lewis MT.
Hedgehog signaling is frequently altered in human breast cancer and constitutive activation of
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smoothened leads to increase in proliferation and ductal hyperplasia in transgenic mice. 29th
U
Annual San Antonio Breast Cancer Symposium, Texas, USA, December 2006.
Moraes RC, Zhang X, Harrington N, Fung JY, Wu M-F, Hilsenbeck SG, Allred C, Lewis MT.
Arrest of the mammary duct growth in mice homozygous for the Ptch1mes mutation. 29th Annual
U U
San Antonio Breast Cancer Symposium, Texas, USA, December 2006.
Adriana P. Visbal, Ricardo Moraes, Michael T. Lewis and Jeffrey M. Rosen. The role ofU
hedgehog signaling in mammary gland development. Baylor College of Medicine Annual
U
Retreat, Lake Conroe, Texas, 2006.
Zhang X, Harrington N, Moraes RC, Lewis MT. Cyclopamine inhibits breast cancer cell growth
U
via hedgehog network-dependent and independent mechanisms unrelated to cholesterol
trafficking. 28th Annual San Antonio Breast Cancer Symposium, Texas, USA, December 2005.
U
Moraes, RC.; Harrington, NN.; Lewis, MT. Disruption of Smoothened (Smo) leads to
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abnormalities during virgin mammary gland development. Gordon Research Conference on
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Mammary Gland Biology, Lucca, Italy, May 2004.
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ABSTRACTS (cont.)
Moraes, R.; Naville, D.; Durand, P.; Birkenkamp-Demtrocker, F.; Orntoft, T. F.; Bégeot, M.
Variation of gene expression induced in DIO (diet-induced obesity mice). 84th Annual Meeting
U U
of the Endocrine Society, San Francisco, June 2002.
Moraes, R. C.; Durand, P.; Naville, D.; Begeot, M. A model of Diet Induced Obesity for the
U
research of target genes in the Hypothalamus-Pituitary-Adrenal axis. French Institute for
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Agronomy Research Annual Meeting, Arcachon, France, 5-6 November, 2001.
Moraes, R. C.; Bagnol, D.; Grino, M.; Bosler, O.; Durand, P.; Naville, D.; Begeot, M.
DIET INDUCED OBESITY (DIO) AND LEPTIN TREATMENT AS A MODEL FOR OBESITY
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STUDY. 5th European Congress of Endocrinology, Turin, Italy, June 2001.
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Moraes, R. C.; Bagnol, D.; Durand, P.; Naville, D.; Begeot, M.
Mise au point d’un modèle d’obésité induite chez l asouris pour la recherché de genes cibles
U
dans l’axe hypothalamo-hypophyso-surrénalien. 12éme Réunion des Groups de Recherche en
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Endocrinologie des Universités de la Région Rhône-Alpes (Franco-suisse), May 4th, 2001.
Said, T.; Moraes, R.C.B.; Sinha, R.; Medina, D. Effect of SAHA on cell growth of two mouse
U
mammary epithelial cell lines that differ in p53 status. ISREC (Institut Suisse de Recherche
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Expérimentale sur le Cancer) Conference – Cancer and The Cell Cycle, Lausanne, Switzerland,
1999.
Sinha, R.; Kiley, S. C.; Lu, J.; Thompson, H. J.; Moraes, R.C.B.; Jaken, S.; Medina, D.
Methylselenicysteine inhibits mouse mammary growth by altering PKC enzyme activity. 1998
Annual Meeting of the American Association for Cancer Research, New Orleans, USA
Barnabas, N.J.; Alvarado, M.E.; Adesina, K.; Moraes, R.C.B; Estrada, S. Calaf, G. and Russo, J.
Role of p53 and mdm2 in the transformation of human breast epithelial cell line MCF 10F
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treated with chemical carcinogens. 1995 Annual Meeting of the American Association for
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Cancer Research, Toronto, Canada.
Barnabas-Sohi, N.; Moraes, R.C.B.; Calaf, G.; Estrada, S.; Alvarado, M.E. and Russo, J.
Overexpression of p53 protein and loss of heterozygosity in chromosome 17p in chemically
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transformed human breast epithelial cells. 1993 Annual Meeting of the American Association
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for Cancer Research, Orlando, Florida, May 19-22, 1993.
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GUEST SPEAKER
Novel Mouse Model: Mammary hyperplasia and accumulation of progenitor cell types in
U U U
transgenic mice expressing constitutively activated smoothened. Baylor College of Medicine,
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The Breast Center Retreat, Lake Conroe, Texas, 2005.
A model of Diet Induced Obesity(DIO) for the research of target genes in the Hypothalamus-
U
Pituitary-Adrenal axis. French Institute for Agronomy Research Annual Meeting, Arcachon,
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France, 5-6 November 2001.
Different models for study of obesity, present approach and perspectives. French Institute for
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Agronomy Research Scientific Commit, Paris, France, 12th October 2001.
Mise au point d’un modèle d’obésité induite chez l asouris pour la recherché de genes cibles
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dans l’axe hypothalamo-hypophyso-surrénalien. 12éme Réunion des Groups de Recherche en
U
Endocrinologie des Universités de la Région Rhône-Alpes (Franco-suisse), May 4th, 2001.
REFERENCES
2B
Available upon request.
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