Engineering Research

KATHRYN DORST

*** ****** **. ****: 631-***-****

Raritan NJ 08869 E-mail: *******.*****@**********.***

EDUCATION

**** **.*. (December), Materials Science and Engineering, Stony Brook University

2012 M.S., Materials Science and Engineering, Stony Brook University, Cum Laude (GPA: 3.58)

2008 B.S., Chemistry, Dowling College, Summa Cum Laude (GPA: 3.98), with departmental honors

METHODS

Mammalian cell culture (MC3T3-E1 osteoblasts - various subclones, ROS cells), Extracellular Matrix (ECM) environment and

proteins, cell-material interactions, gel electrophoresis (agarose, SDS-PAGE, gel zymography), Western blotting, RT-PCR, ELISA,

antibody staining, histological staining, protein adsorption isotherms, protein stamping, data analysis including: time-resolved cell

motion, statistics, clean room techniques, thin-film preparation, micropattern fabrication, silicon wafer cleaning (piranha),

photolithography, wettability studies, laboratory management, interdepartmental collaboration, research mentoring

EQUIPMENT

Fluorescent and phase contrast microscopy, confocal microscopy, SEM/EDAX, Instron, Image J software, Electron-Beam

Lithography, L-Edit CAD software, Origin software, profilometry, ellipsometry, IGOR software, AFM, FTIR (U2B at NSLS), UV-

Vis, synchrotron X-ray diffraction (SAXS and WAXS; X6B at NSLS), synchrotron XANES (X3B at NSLS), Deep Reactive Ion

Etching, Electron beam deposition, GC-MS, HPLC, UV-Vis

PEER-REVIEWED PUBLICATIONS

1. K. Dorst, D. Rammelkamp, M. Hadjiargyrou, Y. Meng, The Effect of Exogenous Zinc Concentration on the Responsiveness of

MC3T3-E1 Pre-Osteoblasts to Surface Microtopography: Part II (Differentiation). Materials 2014, 7 (2), 1097-1112. doi:

10.3390/ma7021097

2. K. Dorst, D. Rammelkamp, M. Hadjiargyrou, D. Gersappe, Y. Meng, The Effect of Exogenous Zinc Concentration on the

Responsiveness of MC3T3-E1 Pre-Osteoblasts to Surface Microtopography: Part I (Migration). Materials 2013, 6, 5517-5532.

doi: 10.3390/ma6125517

3. K. Dorst, D. Rammelkamp, Y. Meng, Osteoblast clonality determines bone mineral deposition. (submission ETA March 2014)

4. Ph.D. Thesis: Physical and Chemical Modifications of Surface Properties Lead to Alterations in Osteoblast Behavior . (2013)

5. Master's Thesis: Micropatterned Anisotropic Topography Directs Osteoblast Migration and Differentiation . (2012)

6. N. Pernodet, V. Jurukovski, J. Fields, A. Fields, A. Ramek, T. Mironav, K. Ghosh, T. Bernheim, K. Hall, S. Ge, L. Slutsky, K.

Dorst, M. Simon, M. Rafailovich. Detecting Cancer Cells in Normal Tissue by Scanning Force Modulation Microscopy.

Microscopy and Analysis 2008 22 (2), 5-8.

CONFERENCE PRESENTATIONS

1. K. Dorst, E. Farquhar, M. Chance, Y. Meng. The Role of ECM Proteins in Mediating Osteoblast Motility and Differentiation.

Poster presentation on graduate research at the International Materials Research Congress XXI, Cancun, Mexico (August 2012).

2. K. Dorst, C. Zhang, Y. Meng. Effect of MMP-Mediated Fibronectin Proteolysis on Osteoblast Motility. Talk on graduate

research given at the Materials Research Society Spring 2012 Meeting, San Francisco, CA (April 2012).

3. K. Dorst, X. Zhao, A. Stein, M. Hadjiargyrou, Y. Meng. The Role of Physical Modulation of Substrate Properties on Osteoblast

Differentiation. Poster presentation on graduate research at the Materials Research Society Fall 2011 Meeting, Boston, MA

(December 2011).

4. K. Dorst, J. Horne, Y. Meng. The Effect of Substrate Properties on Osteoblast Shape, Adhesion, and Motility. Poster

presentation on graduate research at the Sigma Xi Northeast Regional 2011 Meeting, Stony Brook, NY (April 2011).

5. K. Dorst, J. Horne, Y. Meng. A Comparative Study of Osteoblasts and Osteosarcoma Cells in Conditioned Media. Poster

presentation of graduate research at the American Society of Cell Biology, 50th Annual Meeting, Philadelphia, PA (December

2010).

6. S. R. Seidel, K. Dorst. Multi-zonal crystalline systems and self-assembly: a summary of results. Poster presentation on

undergraduate research on my behalf at the International Chemical Congress of Pacific Basin Societies Meeting, Waikiki, HI

(December 2010).

7. K. Dorst, Y. Meng. The Role of Chemical and Physical Modulation of Substrate Properties on O steoblast Adhesion, Motility

and Differentiation. Poster presentation of graduate research at the Gordon Research Conference on Biomineralization 2010,

New London, NH (August 2010).

Page 1

Kathryn Dorst *******.*****@**********.***

8. K. Dorst, A. Stein, Y. Meng. "Adhesion, Migration and Differentiation Behavior of Osteoblasts on Various Surface

Topographies." Poster presentation of graduate research at Brookhaven National Lab's Joint National Synchrotron Light Source

(NSLS) and Center for Functional Nanomaterials (CFN) Users' Meeting 2010, Upton, NY (May 2010).

9. S. R. Seidel; K. Dorst, R. Wilkens, A. Barthelmess, Investigations into multi-zonal crystalline systems. Poster presentation of

undergraduate research on my behalf at the 239th ACS National Meeting &Exposition, San Francisco, CA (March 2010).

10. Dorst, K., Meng, Y. Effect of Surface Topography and Chemistry on Osteoblast Biomineralization. Poster presentation of

graduate research at the Materials Research Society Fall 2009 Meeting. Boston, MA (December 2009).

11. S. R. Seidel; K. Dorst, R. Wilkens, Multizonal crystalline systems based on copper, zinc, manganese, and cobalt. Poster

presentation of undergraduate research on my behalf at the 237th ACS National Meeting & Exposition, Salt Lake City, UT

(March 2009).

12. K. Dorst, S. R. Seidel, S. Spector, M. Jurjevic, R. Wilkens. Crystalline “Candy-Canes”: A Foray into Multi-Zone Crystal

Composites. Poster presentation of undergraduate research at the American Chemical Society's Joint 63rd Northwest/21st

Rocky Mountain (NORM/RMRM) Meeting, Park City, UT (June 2008).

13. J. Alicea, A. Cook, K. Dorst, J. Miller, L. Zaikowski, Energetics of charge separation in medium polarity solvents. Poster

presentation of undergraduate research at the American Chemical Society 232nd National Meeting at Division of Physical

Chemistry, San Francisco, CA (September 2006).

HONORS AND AWARDS

Graduate Assistance in Areas of National Need (GAANN) fellowship (2011-2012; renewed 2012-2013)

Sigma Xi Grants in Aid of Research award (March 2011 & October 2009)

Poster award, Brookhaven National Lab’s NSLS and CFN Joint users meeting (May 2010)

Dowling College Honors Program Scholarship (2004-2008)

Dowling College Presidential Academic Honor Full Tuition Scholarship (2004-2008)

PROFESSIONAL ASSOCIATIONS

Sigma Xi, Scientific Research Society (2011-present)

New York Academy of Science (2010-present)

Materials Research Society (2009-present)

American Chemical Society (2006-present)

COURSES TAUGHT

Stony Brook University

Spring 2013: ESM 353/ESM 696: Biomaterials: Manufacture, Properties, and Applications

Summer 2012: Research Methods, Center for Inclusive Education, REU program in Nanotechnology for Health, Energy and

the Environment

Spring 2012: WSE 187: Introduction to Research (Biomaterials), Women In Science and Engineering program

TEACHING ASSISTANT COURSES

Stony Brook University

Spring 2011: ESM 696: Biomaterials

Fall 2010: ESG 217: Engineering Design I

Fall 2009: CME 201: Sustainable Energy

Spring 2009 & 2010: ESM 350: Advanced Engineering Lab

Fall 2008: CME 101: Introduction to Chemical and Molecular Engineering

OTHER WORK EXPERIENCE

Stony Brook University

President of Materials Science Club (2010-2012)

Materials Science & Engineering senator representative to the Graduate Student Organization (2010-2012)

Garcia Center Educational Outreach: Mentored high school students with research projects (2005-2008)

Dowling College

Science Prep Lab Assistant – Maintained GC-MS, HPLC, UV-Vis equipment and assisted with lab sections of classes (2005-

2008)

Page 2

Kathryn Dorst *******.*****@**********.***

Contact this candidate