Training University

HADEER LAZIM

***-*** **** **** **. West, London, ON N6J 1W6

905-***-**** ******.*****@*****.***

SUMMARY OF QUALIFICATIONS

. Research Associate in Biochemistry Biomedical Sciences Department at

McMaster University

. Microbiologist in Laboratoire de Microbiologie, Centre National de

Greffe Moelle osseuse

. Studies in repair of damaged DNA, with excellence in research

methodology and techniques

. Ten years' experience in scientific research in several countries

. A mature, motivated, flexible and adaptable researcher

. Well-organized, and hardworking and able to focus on multiple projects

simultaneously

EMPLOYMENT HISTORY

Post-Doctoral Fellow (Research Associate), McMaster University,

2009-2013

Hamilton, Canada

. Function and Mechanism of DNA Repair Proteins

. Developing biosensor for detection pathogen bacteria

Scientific Researcher, Centre National des Sciences et Technologies

2006-2008

Nucl aires, Tunisia

. Screeing of Antimicrobial and production by soil bacteria

. Restriction/Modification system in clinical bacterial

. Biochemical characterization of bacterial protease enzymes

. Conducted microp, molecular and chemical testing on meat, seafood

. Conducted antibiotic residue on meat, chicken and milk

Scientific Researcher Laboratoire de Microbiologie, Centre National de

Greffe de 2003-2005

Moelle osseuse,Tunisie

. Antibiotic resistance bacteria, biochemical, molecular and genetic

studies

Scientific Researcher Gene Laboratory, Food Microbiology

2003

University of Royal Veterinary and Agricultural (KVL), Copenhagen,

Denmark

. Restriction/modification system on E.coli, Lactococcus lactis

. Bacteriophage in dairy processing

EDUCATION AND PROFESSONAL DEVELOPMENT

> Postdoctoral Study: McMaster University, Hamilton, Canada

Field: DNAzyme Biosensors for Bacteria Detection

> Ph.D in Biology : University of El-manar, Tunisia

New Restriction Endonuclease Type II from Clinical Escherichia

coli, isoschizomer StuI

> Master of Science: Biotechnology and Genetic Engineering, University

of Baghdad,

> Bachelor of Agriculture Engineering: Animal Science University of

Baghdad

Hadeer Lazim ******.*****@*****.***

COURSES, SEMINARS

. Pedagogic formation for university lecturers: University of Baghdad,

Baghdad 1996

. Application of DNA technology in Health and Agriculture, a continuous

1996 education training course,

University of Baghdad, Baghdad

. Recent techniques in biotechnology, continuous education workshop

1997

. Separation of Bio-products: University of Baghdad, Baghdad

1997

. Study of bacterial restriction endonucleases: University of Royal

Veterinary and 2003

Agricultural (KVL), Copenhagen, Denmark

. Participation in 'the 6th Franco-Maghrebi School of Molecular

2004 Biotechnology' in Chott-

Mariem, Sousse, Tunisia

. Radio-Isotop Training: McMaster University, Hamilton, Ontario

2009

. Business Conduct Excellence course, MITACS Skills Training and

2010 Entrepreneurship Program,

Hamilton, Canada

. Foundations of Project Management I course, MITACS Skills Training and

2010 Entrepreneurship Program, Hamilton,

Canada

. Biochemistry and biomedical sciences', Safety and Awareness training,

2011 McMaster University, Hamilton,

Canada

. Published scientific papers are available on my Curriculum Vitae

PUBLICATIONS

1 1-Essouissi I, MALEK N, MEJRI N, GUIZANI S, LAZIM H, SAIDI M. (2014)

SYYNTHESIS AND BIOLOGICAL EVALUATION OF 99MTC-ECF: A NEWETHIONAMIDE

DERIVATIVE FOR TUBERCULOSIS DIAGNOSIS. Journal of Radiioanalytical and

Nuclear Chemistry(10.1007/s10967-014-3059-4)

2-Nedra Slama, Houda Mankai, Ameni Ayed, Karim Mezhoud, Catherine

Rauch, Hadeer Lazim, Insaf Barkallah, Maher Gtari, Ferid Limam.(2014)

Streptomyces tunisiensis sp. nov., a novel Streptomyces species with

antibacterial activity.J. Antonie van Leeuwenhoek. Vol.105 (2), p.377

3- Sghaier H., Bouchami O., Desler C., Lazim H., Saidi M., Rasmussen L.,

Hassen B. (2012). Analysis of the antimicrobial susceptibility

of the ionizing radiation-resistant bacterium

Deinococcus radiodurans: implications for bioremediation of radioactive

waste. Ann Microbiol.

Vol: 62, Issue 2, 493-500

4- Monsur Ali M., Sergio D. Aguirre, Lazim H., and Yingfu Li (2011).

Fluorogenic DNAzyme Probes as Bacterial Indicators. Angew. Chem. Germ.

Ed.,Vol: 123, 3835-3838

5- Monsur Ali M., Sergio D. Aguirre, Lazim H., and Yingfu Li (2011).

Fluorogenic DNAzyme Probes as Bacterial Indicators. Angew. Chem. Int. Ed.

Vol: 50, 3751-3754

6-Lazim H., Slama N., Mankai H., Barkallah I. and Limam F. (2010)

Enhancement of oxytetracycline production after gamma irradiation-induced

mutagenesis of Streptomyces rimosus CN08 strain. World J Microbiol

Biotechnol. 26:1317-1322.

7- Lazim H., Mankai H., Slama N., Barkallah I. and Limam F. (2009).

Production and optimization of thermophilic alkaline protease in solid

state fermentation by Streptomyces sp.CN902. J Ind Microbiol Biotechnol.

Vol 36(4):531-537.

8-Lazim H., Nedra Slama, Abbassi Mohamed Salah, Insaf Barkallah, Assia

Ben Hassen and Ferid Limam (2008). Protoplasting impact on polyketide

activity and characterization of the interspecific fusants from

Streptomyces spp. Afr.J. Biotech. Vol. 7 (17), pp. 3155-3161.

9- Lazim H., Abbassi Mohamed Salah, Nedra Slama, Insaf Barkallah, Assia

Ben Hassen and Ferid Limam (2007). Biochemical detection of a metallo-?-

lactamase in carbapenem resistant strain of Streptomyces sp.CN229 isolated

from soil. Ann.Microb vol. 57, issue (4) 515-519.

10- Lazim H., Josephsen Y., Ben Hassen A., Belhadj O. (2004) Identification

of Escherichia coli plasmid encoded Type II Restriction / Modification

System (accepted in October 13, 2004). Journal of medical safety.

11- Lazim H., Josephsen Y., Ben Hassen A., Belhadj O. and Limam F. (2005).

Eco1524I, a type II restriction endonuclease: Isolation, partial

purification and characterization. Applied Biochemistry and Biotechnology,

Vol 125 (2):189-200.

12-Lazim H. (1999). Optimisation of Streptomyces griseus pronase production

by solid substrate fermentation. Iraqi J. Sci. Vol 40B, No.3. 15-26.

13- Al-Arar I., Ali N. and Lazim H. (1999). Detection of Anti-tumour

agent produced by local isolates of streptomyces. J. biotechnology

research, Vol l. No. 1:54-67.

14-Lazim H. and Ali N. (1998). Production and purification of penicillin

from local isolates of fungi. J. Iraqi Microbiological Society Vol. 10(1)

97-105.

15-Lazim H. and Ali N. (1998). Production and purification of streptomycin

from local isolates of streptomyces . Iraqi J. Science Vol. 40 (1) 422-429.

16- Lazim H., Ali N. and Al-Bakri G. (1997). Streptomycin and carbenicillin

resistance plasmids from local streptomyces strain. Iraqi J. Science Vol 39

(4): 135-140.

17- Lazim H., Ali N. and Al-Bakri G. (1997). Preparation, regeneration and

fusion of protoplast from

local streptomyces isolates. Iraqi J. Science Vol. 39(2): 606-624.

18- Lazim H., Al-Bakri G. and Ali N. (1996) .Rapid method for the isolation

of plasmids DNA from local

streptomyces isolates J. Iraqi Microbiological Society Vol.

8(2):3-9.

PATENTS ADDRESSED TO INNORPI

PATENT No. SN 05127 (2005): Eco1524 I, a new restriction endonuclease Type

II isolated from clinical strain of Escherichia coli1524a, isochizom re

StuI. Patent Application Addressed in accordance with law No.2000-840

Dated 24-8-2000

PATENT No.SN 05128 (2005): Selection of strain of Bacillus

amyloliquefaciencs from soil, hyper productive a restriction

endonuclease Type II named Bam18I: Isolation and biochemical

characterization of the enzyme.Patent Application Addressed in

accordance with law No.2000-840 Dated 24-8-2000.

PATENT No. SN 05136 (2005):Isolation and biochemical characterization of a

plasmid pHLT5 from Escherichia coli1524a which encodes a restriction

and modification of Type II.Patent Application Addressed to INNORPI in

accordance with law No.2000-840 dated 24-8-2000.

References

Professor Murray Junop

1200 Main Street West,

Institute for Infectious Disease Research

HSC 4N20A

McMaster University

Hamilton, Ontario,

Phone: 905-***-**** Ext.22912

Canada

******@********.**

L8N 3Z5

Professor F rid Limam

Laboratoire des substances biologiquement actives, BP-

901, 2050 Hammam-lif,

Centre de Biotechnologie, Technopole Boj-Cedria,

Tunisia

Institut National de Recherche Scientifique et Technique

Phone : +216-**-***-***

***********@*****.**

Professor Ezzedine Aouani

Bezerte,

Department of Biology,

Tunisia

Faculty of Science of Bizerte,

University of 7 November of Carthage

***************@*****.**

Professor Assia Ben Hassen

Rue Djebel Lakhdhar

Chef service de Microbiologie laboratoire,

Bab Saadoun-1006

Centre National de Greffe de Moelle Osseuse (C.N.G.M.O.) Tunis

Phone : +216-**-***-***

Tunisia

****************@*****.***

Professor Jytte Josephsen

Rolighedsvej 30DK-1958

Department of Dairy microbiology and Food Science

Frederiksberg C Building 2-74

The Royal Veterinary and Agriculture University KVL

Room T474

Phone +45 35283232

Copenhagen

Cell : +45 28 75 40 94

Denmark

**@***********.***

DETAILED CURRICULUM VITAE AND AVAILABLE UPON REQUEST

Contact this candidate