Scientist
Resume:
LAWRENCE PORCO
P.O. BOX ****
BRONX, N.Y.*****
*******@*****.***
TECHNICAL SKILLS
-Pharmacokinetic studies with rats and mice involving anti-cancer and anti-
obesity compounds
-GC, GC/MS, NMR, UV/VIS, ATOMIC EMISSION, FTIR, IR, XRD, XRF, HPLC, AA
-SDS-PAGE, RIA, EMIT, ELISA, IFP
-Paper, thin-layer, and column chromatography
-in vitro pharmacological techniques and radioisotope incorporation studies
-DNA ligation, transformation, transfection, and restriction techniques;
PCR
-Agarose DNA mini-gel electrophoresis; Phenol/chloroform extraction
-Lowry and Bio-Rad protein determinations
-Titrations and steroid extractions
-Long- and short-term culture of human megakaryocytes and fibroblasts;
Organ culture
-Sterile techniques including sterile preparation of media and buffers
-Familiarity with liquid and agar cultures
-Preparation of antisera
-Immunofluorescent and morphological staining
-Differential, boyant density, and sucrose gradient centrifugation;
Velocity sedimentation
-Transmission electron, light, phase contrast, and ultraviolet microscopy
-Cell differentials and chromosome banding
-Photomicrography and photographic processing and development
-Animal tissue oxidation, surgery, tumor transplantation, hormone pellet
implantation, catheterization
-Harvesting of tumor cell line and injection into animal
-Blood banking: Type/crossmatch; pooled platelets; release of blood
components
-Hematology: CBC; Manual Diffs; PT/PTT; sed rates; Advia 120 analyzer
-Clinical Chemistry: Vitros 250 Chem System; Beckman LX-20; Abbott Axsym,
Adx/Tdx; Olympus 640/680
-Urinalysis: Bayer Atlas & Adventus Cliniteks & Microscopy
-Serology: BioMerieux miniVidas (MMRV-Z); Card tests for Syphilis RPR,
Mono Heterophile Ab., RF
NON-TECHNICAL SKILLS
-Performed quality control during instrumental analyses as required
following GLPs
-Interaction with clinical personnel (reporting test results/interfacing
with drug monitoring programs)
-Accessioning of lab specimens
-Computer experience: Microsoft Access, Excel, Word, Outlook; Lotus Notes
EMPLOYMENT
2/13 - 5/13 Antech Diagnostics Lab, Lake Success, LI, NY
temp. Veterinary Medical Lab Technologist Generalist Floater
Operated Beckman Olympus 640/680 Chemistry analyzers, Advia 120
Hematology analyzer, Bayer Clinitek Atlas & Adventus Urinalysis
analyzers, Siemens Immulite 1000 analyzer, and Trinity Biotech
KC4 Delta Coag unit.
Traveled as a FT vacation/sick relief floater working at the
various company satellite STAT labs analyzing urine, blood,
and serum samples from veterinary clinics and hospitals.
11/03 - 12/12 NYC Transit Rapid Transit Operations
Motorman/Train Operator
Operate subway trains as a Motorman in revenue and non-revenue
service in the IRT.
Took this job due to a 9-month layoff from pharma industry with
no prospects for employment. Would consider another
permanent/contract CRA or lab position again.
LAWRENCE PORCO
P.O. BOX 1019
BRONX, N.Y.10462
*******@*****.***
9/02 - 3/03 Barton & Polansky Associates
Layoff Division of ICON Clinical Research
Clinical Research Associate
Worked on Phase IIIb/Expanded Access anti-HIV study enrolling patient
(5 pts/site;40 sites).
Made monitoring calls in lieu of actual site visits; reviewed
regulatory documents for accuracy; wrote
monitoring call reports, also confirmation and follow-up
letters to the site; on behalf of site requested exemptions
from sponsor for patient enrollment and reported protocol
deviations/violations to sponsor; followed patient SAEs
obtaining discharge summaries, labs.
4/02 - 9/02 Mt. Kisco Medical Group/NYU Health Center
Medical Lab Technologist
temp. Analyzed urine and blood in a 100+ doctors clinic
and student health center performing urine
microscopics, pregnancy tests, and CBCs, Sed Rates, PT/PTTs,
making smears and staining slides, chemistry panels, serology
tests, and vaginal screening panels (GCT).
8/01 - 4/02 Ingenix Pharmaceutical Services Clinical
Research Associate
Worked on Phase III, IV, and Expanded Access anti-HIV
studies.
Coordinated patient enrollment based on
inclusion/exclusion criteria; generated queries to
investigators; interfaced between study sites and
sponsors; issued/reviewed regulatory
documents; proofread protocols, case report forms,
investigator agreements, ICs.
2/01 - 8/01 Purdue Pharma, L.P.
International Reg. Affairs Assistant
temp. Respond to inquiries for information from various company overseas
affiliates to satisfy regulatory requirements. Assist in
other company departments, e.g., Drug Safety, Labelling, and
Biostatistics as required. Brought documentation notebooks into
compliance with company's SOPs.
7/00 - 11/00 Regeneron Pharmaceuticals, Inc.
Research Associate
temp. Performed PK studies with rats and mice (dosing
and canula/tail bleeds) involving anti-cancer
and anti-obesity test compounds. Collected the serum and
analyzed via ELISA. Also worked in the mouse transgenic
group utilizing embryonic stem cells, PCR, and Southern blots
to study knockouts to identify various gene functions.
3/99 - 2/00 Bronx VA Hospital lab
Clinical Lab Technologist
Worked nights and weekends in a Federal Government hospital lab
performing blood, urine, CSF, and other biological fluid
analyses interfacing with the medical staff reporting results
to the floors from the Hematology and Chemistry sections. Also
worked in the Blood Bank type and crossmatching patient samples
for units of blood releasing packed cells, cryoprecipitate,
fresh frozen plasma, and platelets. Worked independently
running all 3 sections at night alone on the shift.
6/98 - 10/98 Lederle Laboratories (Wyeth-Ayerst Research)
Drug Safety & Metabolism Chemist
temp.
Drug Disposition Dept.
Performed pharmacokinetic studies measuring via Packard
automated tissue oxidizer and scintillation
counter novel carbon-14 labelled compounds distributed in
animal tissues. Also extracted cold test compound metabolites
from various animal plasmas preparing them for HPLC and LC/MS
analyses. Kept neat updated study logbooks and interfaced with
other departments concerning studies.
LAWRENCE PORCO
P.O. BOX 1019
BRONX, N.Y.10462
*******@*****.***
9/91 - 4/98 U.S. Customs Service Lab
Regulatory Analytical Chemist
GC/MS, GC, IR, XRayF, XrayD, NMR, UV, AES, AA; Narcotics
Intervention
Analyzed various imported products to determine duty
classification, e.g., Organic substances
(chemical/pharmaceutical intermediates or finished products,
petrochemicals, steel, plastics, polymers, rubber) as well as
inorganic products (colors, pigments, stone tiles, glassware,
china). Helped create narcotic SOPs and routinely performed
inhouse narcotics and precious metals audits/inventory. Worked
on narcotics destruction committees including random drug
analysis and disposal via incineration. Performed wet chemistry
techniques, e.g., quantitating tricalcium phosphate content
for bone china and lead sulfate in leaded glass to determine
lead monoxide content.
1990/99 Massey Analytical Lab
Clinical/Forensic Toxicologist-Supervisor
Pvt. CT. lab. NIDA certified. TLC,
EMIT, GC/MS; Forensic Toxicology
Setup/ran on-site drug screen test lab for local nuclear
power plant.
Also supervised five technicians in the TLC section and
performed in-house urine
drug screen tests using the Monarch system and assisted on
confirmations with H-P GC/MS.
2/89 - 1/95 Long Island Jewish Medical Center
Routine/STAT Clinical Technologist
Dept. of Biochemistry. ADx/TDx, GC, EMIT,
GC/MS; drug/alcohol analysis
Performed emergency blood/urine drug test
analyses for local hospitals.
Assisted in creating laboratory SOPs for Abbott
TDx/ADx.
Ran Toxicology Dept. solo off-shift. Worked several
shifts consecutively when needed.
9/87 - 8/89 Clin-Path/ToxLab
Routine/Emergency Toxicologist
Pvt. L.I. lab. GC/MS, EMIT, RIA, HPLC;
Blood/urine drug/alcohol analysis
Supervised night shift. Performed emergency
toxicology blood/urine drug panels
for local hospitals.
Assisted in routine toxicology urine drug panels using
Cobas Mira.
Interpreted qualitative/quantitative values reporting
results to hospital staff.
3/86 - 9/87 NYS Div. of Substance Abuse Services
Forensic Chemist-Supervisor
TLC, EMIT; Forensic Toxicology - urine drug
analysis of public servants
Working supervisor over ten technicians on the routine
toxicology floor.
Read TLC plates and worked on the Syva Autocarousel.
4/85 - 3/86 Columbia Univ. at Col.-Presb. Hosp.
Research Technician
grant Dept. of Biochem./molec. bio. lab. DNA
hybridization/staining, cell culture
Studied 3T3 fibroblast cell transformation by modified Moloney
MLV with Abelson genome measured by tyrosine kinase
activity.
9/84 - 4/85 Ayerst Laboratory, div. of AHPC.
Medical Research Associate
Pvt. pharmaceutical co. Set-up/monitor off-
site test drug protocols.
Worked in the Bioavailability Phase I group
testing steroid compounds.
Organized Phase I studies for transdermal patch tests and
traveled to various
domestic sites to monitor them.
LAWRENCE PORCO
P.O. BOX 1019
BRONX, N.Y.10462
*******@*****.***
9/81 - 9/82 Sloan-Kettering at Rockefeller Univ.
Research Technician
grant Dept. of Surgery. Breast cancer
research; animal surgery, tissue culture
Performed tumor implantations and transfers in
rats and nude mice models.
Acquired strong experience in Hormonal Biochemistry
working with Dr. Leon Bradlow.
Studied methods for early detection of breast cancer.
LICENSING
N.Y.C. Dept. of Health: Clinical Lab Supervisor-Area 33C
Clinical Lab Technologist-Areas 30, 33, 33A, 33C
Area 30-Therapeutic Substance Monitoring/Quantitative Toxicology
Area 33-Drug Analysis: Qualitative (Routine)
Area 33A-Emergency Toxicology
Area 33C-Forensic Toxicology
EDUCATION
St. John's University M.S in Pharmacology/Toxicology Rho Chi
Honor Society
Fordham University M.S. in Biology (Cytogenetics) Dean's List
Fordham University B.S. in Biology (Pre-Med) Regents
Scholarship
The Bronx H.S. of Science
HONORS AND AWARDS:
. U.S. Customs monetary award for updating narcotics inventory and
assisting the Petroleum Chemist in inspecting private gauging
laboratories.
. Member of Rho Chi Honor Society with 8 straight A's in graduate courses
(St. John's Univ.).
. Made the Dean's List with a GPA 3.5 or higher (Fordham University
graduate program).
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