Assistant Research
Resume:
February ****
Mary M Brown
*** * ******* *** #**, Chicago IL 60622
*************@*****.***
Education
Bachelor of Science in Molecular and Cellular Biology
University of Illinois at Urbana-Champaign
2008-2012
Experience
Research Scientist, Loyola University Chicago Burn & Shock Trauma Research Institute. Maywood, IL
Conducted research on the pathophysiologic response to burn injuries with a focus on remote organ damage.
* Assessed post burn pulmonary inflammation in the presence and absence of therapeutic intervention by examining cellular changes and functional deficits through histologic analysis and whole body plethysmography.
* Developed intracellular immunofluorescent staining protocols for determination of pulmonary macrophage polarization. Phenotypic changes were then confirmed on an mRNA and protein level through real time polymerase chain reaction and multiplex bead arrays, respectively.
* Responsible for animal experiment design and execution including administration of drugs, animal sacrifice and tissue harvesting and processing.
* Accountable to the Institutional Animal Care and Use Committee for maintaining approval of proposed and ongoing animal experiments through initiating new and updating existing Animal Components of Research of Protocols.
* Conducted data interpretation through statistical analysis and regular presentation of findings in the context of therapeutic efficacy.
2012-present
Research Assistant, National Soybean Research Center. Urbana, IL
Identified genetic differences in soybean plants that provided protection from a disease causing fungus, Phakopsora pachyrhizi.
* Characterized genotypic differences in disease-susceptible and resistant soybean plants by genetic sequencing and analysis.
* Created and implemented a catalogue system for seeds.
* Responsible for maintenance and development of research specimens including field care and greenhouse conditions.
2012
Research Assistant, Institute for Genomic Biology. Urbana, IL
Led novel antibiotic discovery efforts derived from Streptomyces cultures
* Characterized Steptomyces phosphonates and screened protein isolates for antibiotic efficacy.
* Maintained Steptomyces cultures, collected specific phosphonates, and conducted antimicrobial efficicacy testing.
2011- 2012
Laboratory Assistant, Illinois Natural History Survey. Champaign, IL
Discovered a previously unidentified species of stonefly indigenous to Illinois
* Collected specimens and environmental data during extensive trips into the field.
* Used DNA sequencing and molecular techniques to parse out two distinct species of stonefly.
* Learned techniques such as DNA extraction, DNA cleanup, DNA sequencing and polymerase chain reaction, water chemistry collection and using Paup software.
2009-
2010
Team Researcher, International Genetically Engineered Machine Competition. Champaign, IL
Co-led a team of undergraduate researchers in a project entitled “Echiver”, a plasmid designed to store specific information that could be turned on and off under certain environmental conditions.
* Became proficient in cloning techniques and cell culture.
* Wrote and distributed a monthly newsletter.
* Participated in public presentations regarding synthetic biology education.
2011-2012
Personal Development
* Developed educational scientific demonstrations to be shown at nearby elementary schools.
* Participated in professional seminars put on by Loyola’s Burn and Shock Trauma Research Institute and the Alcohol Research Program.
* Volunteered at Community Health Clinic, processing patient samples in the lab.
2011
2012-present
2013-present
Publications and
Peer-Reviewed Abstracts
* Chen MM, Zahs A, Brown MM, Ramirez L, Turner JR, Choudhry MA, and Kovacs EJ. 2014. Restoration of the gut-liver axis attenuates pulmonary inflammation after intoxication and burn injury in mice. Journal of Leukocyte Biology, under review
* Chen MM, Brown MM, Kovacs EJ. The Role of the Liver in the Aberrant Inflammation Seen When Ethanol Exposure Precedes Burn Injury. Annual Research Society on Alcoholism Scientific Meeting (2013), Orlando, FL.
Published in Alcoholism: Clinical and Experimental Research 37:6 (suppl 1)
* Chen MM, Zahs A, Brown MM, Kovacs EJ. Restoration of the gut-liver axis after burn injury in intoxicated mice attenuates pulmonary inflammation. Society for Leukocyte Biology 46th Annual Meeting (2013), Newport, RI
* Chen MM, Zahs A, Brown MM, Kovacs EJ. Alteration in the gut-liver axis mediate pulmonary inflammation after burn injury and is exacerbated by prior intoxication. American College of Physicians Illinois Chapter Scientific Meeting (2013), Rosemont, IL
* Chen MM, Zahs A, Brown MM, Kovacs EJ. Bacterial translocation and hepatic damage drive pulmonary inflammation when intoxication precedes burn injury in mice. St. Albert’s Day Research Forum (2013), Maywood, IL
* Chen MM, Zahs A, Brown MM, Ramirez L, and Kovacs EJ. Prophylactic sterilization of the gut confers hepatic protection after intoxication and burn injury in mice. Annual American Physician Scientist Association Joint Meeting (2014), Chicago, IL
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