Assistant University

Difei Jiang

***** ********* ** *** *****, CA ****9

716-***-**** ********@*******.***

EDUCATION

University at Buffalo, the State University of New York

M.S. in Medicinal Chemistry, Department of Chemistry, September 2013

Thesis: Application of Click Chemistry towards the Synthesis of Bifunctional Stapled Peptides. Advisor: Professor Qing Lin

Sichuan University, Chengdu, China

B.S. in Medicinal Chemistry West China School of Pharmacy, July 2011

RESEARCH EXPERIENCE

Medicinal Chemistry Research Assistant, University at Buffalo, May 2012- September 2013

Medicinal and Organic Chemistry Experience

Synthesized Peptides and amino acid derivatives to be used to develop potential peptide anti-cancer drug candidates

Synthesized small molecules for use in three projects focused on novel anti-cancer drug candidates

Instrumentation and Analytical Chemistry Experience

Purified compounds with Gilson Brand HPLC systems and maintained the instrument

Developed methods on Gilson Brand HPLC systems (preparative& analytical)

Characterized peptides and proteins with LCQ type LC/ESI-MS instrumentation and maintained the instrument

Developed different methods for peptide synthesis using Protein International Peptide synthesizer equipment

Maintained and fixed Protein International Peptide synthesizer equipment

Characterized compounds using Varian NMR instruments, IR and UV

Utilized pH meter, centrifuge and analytical balance to prepare for experiments

Biochemical and Cellular Characterizations Experience

Cultured K562, HL-60, and U937 Cell lines for biological assays

Performed cell viability assays and enzyme activity assays to evaluate the biological activities of the compounds

RELATED EXPERIENCE

Organic Chemistry Teaching Assistant, University at Buffalo, August 2012- May 2013

Reviewed homework and problem sets, supervised and instructed 15-25 students during experiments

SKILLS

Medicinal and organic chemistry

Organic synthesis and purification Solid phase peptide synthesis chromatography

Analytical chemistry

HPLC LC-MS NMR IR UV/VIS Centrifuge pH meter Analytical balance

Biochemistry

Mammalian cell culture Cell viability assay Enzyme activity assay

Language

Fluent in Chinese

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