Curriculum Vitae
Personal Information
Name: Zhang, Qiuye (Frank), MD, PhD Candidate
Address: **** ********** ****, *******, ** 38016
E-mail: *******@*****.***
Tel (H): 901-***-****
Cell phone: 901-***-****
Status: permanent resident (Green Card holder)
Education
08/2007 – Present Univ. of Tennessee Health Science Center, Memphis, TN
Dissertation: Development of New Vaccine Formulations with
Adjustable Delayed Immune Response
Expect PhD in Pharmaceutics in December 2013
08/2003 -- 01/2004 Graduate student Major: Developmental Biology
Institute of Zoology
Chinese Academy of Sciences, Beijing, China
09/1992 -- 07/1999 Doctor of Medicine
Harbin Medical University, Harbin, China
Career History
04/2005 -- 08/2007 Senior Research Assistant
Department of Clinical Pharmacy
Univ. of Tennessee Health Science Center, Memphis, TN
03/2004 -- 04/2005 Research Assistant
Department of Physiology & Biophysics
Univ. of Tennessee Health Science Center, Memphis, TN
07/2002 -- 08/2003 Attending Physician and Assistant Professor
Department of Obstetrics & Gynecology
Reproduction & Genetics Center
The Second Hospital of Harbin Medical University, Harbin, China
07/1999 -- 07/2002 Resident & Instructor
Department of Obstetrics & Gynecology
Reproduction and Genetics Center
The Second Hospital of Harbin Medical University, Harbin, China
Major Areas of Interest & Expertise
Vaccine formulation and vaccine delivery systems (In Situ Implant and Microparticle
with lyophilized antigen)
Sustained release biodegradable injectable formulations (In Situ Implant)
Immediate release and sustained release solid dosage forms (tablet, capsule)
Professional Skills
1. More than five years’ experience in development of vaccine formulation and
vaccine delivery system. (My PhD project)
2. From 2009 to 2013, worked as an instructor teaching granulation and tablet
compress in the highly popular “Hands-on Course in Tablet Technology” hosted
by the University of Tennessee. As the only hands-on course in tablet technology
in the United States, it has trained more than 2,000 professionals in
pharmaceutical industry and regulatory agencies from 13 countries since 1998.
3. Certificates from University of Tennessee: “Hands-On Course in Aseptic
Processing” and “Hands-on Course in Tablet Technology”
4. Preformulation studies, granulation for solid dosage forms (high shear
granulation, extrusion-spheronization, hot-melt granulation, fluid bed granulation
and roller compaction), tableting, coating (pan coating and fluid bed coating),
spray dry, dissolution and disintegration tests, development of analytical methods,
such as HPLC and NIR.
5. Techniques for bacterial culture and cell culture of primary human & mammalian
cells and cell lines.
6. Molecular biology techniques
Enzyme-linked immunosorbent assays (ELISA).
Extraction of DNA, RNA from bacteria and mammalian cells
Gel electrophoresis (agarose, polyacrylamide, SDS-PAGE)
Real-time PCR
Transfection of DNA into mammalian cells
7. Protein analysis assay such as Western blot, Immunoprecipitation, pull down
assay
8. Morphological techniques such as immunofluorescent and immunohistochemistry
staining, light microscopy, fluorescent microscopy and confocal microscopy
9. Software usage such as Microsoft word, Microsoft Excel, Microsoft Powerpoint,
statistical analysis software (SAS)
Publications:
1. Mishra J, Zhang Q, Rosson JL, Moran J, Dopp JM, Neudeck BL(2008)
Lipopolysaccharide increases cell surface P-glycoprotein that exhibits diminished
activity in intestinal epithelial cells. Drug Metab Dispos. 36(10):2145-2149
2. Neudeck BL, Zhang Q, and Mishra J (2007) P-glycoprotein Influences β-catenin
Cellular Localization and Nuclear Translocation. Pharmaceutical Sciences
World Congress 2007, Amsterdam, Netherland.
3. Rosson J, Mishra J, Zhang Q, and Neudeck BL (2006) Intracellular bacteria
activate intestinal P-glycoprotein. American College of Clinical Pharmacy 2006
Annul Meeting, St. Lious, USA.
4. Mishra J, Neudeck BL, and Zhang Q (2006) Activation of the Pattern
Recognition Receptor Toll-like Receptor-4 Leads to Increased Membrane
Targeted P-glycoprotein with Diminished Activity. 2006 AAPS Annual Meeting
and Exposition, San Antonio, USA.
5. Chen Y, Zhang Q, Zhang Y (2002) Gene Expression and regulation of Blastocyst
Formation. Developmental & Reproductive Biology, 11(1): 75-81.
6. Chen Y, Zhang Q, Zhang Y (2001) Molecular Biology Techniques Applied to
Preimplantation Genetics Diagnosis. Chinese Medical Journal, 116(6): 49-54.
7. Zhang Q, Wang A (1996) Protection Effects of KAL to Lipid Being Peroxidated
in Myocardial and Brain Mitochondria. J. of Harbin Medical University, 6: 32-
35.
8. Zhang Q (1996) MCP-1. Cytokines Ed 1. Chap. 32.
9. Zhang Q (1996) The Reform of Medical Education to the 21st Century. The
Collection of First Medical Student Conference between Taiwan and
Mainland 1-4.