Management Software

Micah K. Taylor

**** ******** ******, **********, ** 45223

(H): 513-***-**** & (C): 707-***-****

Email: acbajk@r.postjobfree.com

OBJECTIVE: Scientist with 10+ years experience seeking opportunity

supporting the pharmaceutical, biotechnology, or manufacturing

industry.

EDUCATION: Truman State University, Kirksville, MO

BS Biology, BS Chemistry May 2000

Undergraduate RA & TA from 1997-1999; Research focus on

characterization, functionalization and assay of colloidal Au

EXPERIENCE:

02/13-Present Sperry & Rice Manufacturing Co. LLC - Quality

Manager/Chemist

Oversees implementation of and alignment to organization's ISO

9001-2008 Quality Management System (QMS); Oversees and gives

direction on organization's Corrective Action/Preventive Action

(CAPA) process which requires data driven root cause analyses

(RCAs), collaboration with production and management staff to

implement Plan-Do-Check-Act (PDCA) cycle, customer/client

advocacy, and setting compliance policies and guidelines; Also

responsible for promoting an environment of continuous

improvement around key performance indicators and supporting a

lean manufacturing model by developing effective resource

utilization strategies; PPAP drafting with first piece approval

and capability assessments; Expected to also leverage chemistry

background in optimizing and troubleshooting rubber parts

compounds and formulations; Project Management w/Training and

Responsibility Delegation; Asset Calibration/Management; Data

and Records Management; High Level Liason; Routine use of 8Ds,

FMEAs, Control Plans, SPC, GRR and MSAs.

04/12-08/12 Kelly Svcs, Cincinnati, OH - QC Chemist

cGMP analysis and documentation of finished products and stability

samples in FDA regulated environment; Familiarity and compliance

with 21 CFR 210, 211 and relevant pharmacopeia (USP); Use of

eDOCs to retrieve SOPs and Test Methods; Use of Waters HPLCs,

Detectors, and Empower software to perform a variety of assays

(isocratic, gradient, RP, and NP), including content uniformity

(CU), related substances, and product validation; Familiarity

with system suitability requirements, composites analysis, and

bracketing standards; Use of cGMP volumetric lab techniques and

reagent expiration; Use of differential pulse polarography (DPP)

to perform finished product CU; Use of FTIR to perform finished

product and product closures ID; Use of caliper measurements to

ID product closures; Performed friability protocol for finished

products; Complied with cGMP protocols for handling of USP and

other standards.

10/06-12/11 Codexis Inc., Redwood City, CA

Research Associate I (Analytical Biochemistry)

Job Duties: Assisted with transforming process chemistry

criteria into robust, relevant multi-tiered medium throughput

assay protocols; Acquired and maintained familiarity with lab

automation; Carried out and consistently validated and adjusted

developed assay protocols in multidisciplinary team environment;

Assisted with population analysis and data handling in LIMS;

Participated in lab organization, housekeeping, safety and

maintenance activities; Generated technical updates and monthly

reports where appropriate. Employed critical thinking and

attention to detail; Multi-tasked and produced quality results

under tight timelines; Excellent data handling and meticulous

documentation skills; Persistent and creative; Excellent

communication skills; Good planning, time management and

organizational skills; Employed a working understanding of

Molecular Biology

Projects: Assisted in the development of a KRED mediated

biocatalytic route to the Duloxetine (Cymbalta) API for the

generics market; Assisted in the development of a novel panel of

Ene Reductases that showcased a broad array of enzymes with

varying degrees of enantiomeric purity, substrate specificity

and specific activity to be used by pharma innovators to

evaluate "hits" for novel biocatalytic routes for molecules or

APIs of interest; Assisted within a matrix-based Bioindustrials

project on the development of a thermostable low cell load

ethanolagen that could utilize hexose and pentose sugars from

non-food source biomass at relatively high rates and within the

presence of known inhibitory compounds for the eventual

production of a sustainable, cost effective biotethanol product;

Ethanolagen-Strain Characterization; Ethanolagen-XRDK Pathway

Evolution; Ethanolagen-XI Pathway Evolution; Detergent Alcohols;

Systems Approach Using DoE-driven HTP Assays; Designed

Experiment for FX/Tecan (DEFT) Macro; Designed & Collaborated to

Implement Freezer Archival & Retrieval Tracking System

4/06-10/06 Kelly Svcs/Affymetrix Inc., South San Francisco (SSF), CA

Research Assistant II (SNP Discovery Svcs/Genotyping)

500K services team member at SSF producing precise, reliable and

robust genotyping data for various customers. Participation in

all steps of the assay from setting up PCR or enzymatic

reactions in large scale to the hybridization, washing and

scanning of hundreds of arrays per day.

5/05-4/06 On Assignment/Parallele Bioscience, SSF, CA

Research Associate I (Molecular Biology/Assay Dev)

Worked with a team of scientists and research assistants in

developing and optimizing a high throughput DNA variation

detection technology, Variation Scanning by Mismatch Repair

Detection (VS by MRD). Tasks included performing research

activities to improve the assay by optimizing many steps

relating to DNA manipulations and bacterial transformation.

Manipulations of E.coli bacteria: growth media preparation,

competent cell preparation, and transformation; Molecular

biology: Plasmid purification, restriction digestion, PCR

optimization, gel electrophoresis

4/02-11/04 Nanoplex Technologies Inc., Menlo Park, CA

Asst. Scientist I & II (Engineering, Software Dev., Assay Dev)

Reliable manufacture (electroplating) of Nanobarcodes particles

to be used in a variety of contexts including R&D, evaluation,

collaborative and service. Used both optical and electronic

microscopies to QC and characterize the particles. The optical

microscope was a Zeiss Axiovert S-100 adapted for HTS and the

electronic microscope was a Hitachi S-800 SEM with DIC.

Responsible for written quarterly reports to grant provider

(NIST) and a minimum of one monthly technical update in

Powerpoint. Developed multiplexed bioassays on Nanobarcodes

particles using four techniques: hybridization, ligation,

proximity and molecular beacon. Augmented assay development

with software development of SNP database in Access and a

variety of macros and Excel tools for relevant Nanobarcodes

particles statistics.

SKILLS: LABORATORY

Agilent HPLC/GC, Agilent 2100 Bioanalyzer, Waters HPLC, VA

Computrace Metrohm Electrochemical Analyzer (DPP), FTIR, Caliper

Measurements, Shake Flask Preparation, volumetric titration,

OD600, total protein analysis, Biomek FX/NX (Biomek Software),

solutions prep, organic separations, glycerol stocks, UV-vis,

Pico-Green Quantitation, agarose gel imaging, manual and

automated electroplating, inverted optical microscope, SEM, Urea-

PAGE, PCR, plasmid/vector isolation, DNA gel extraction, Qiagen

plasmid purification, fluorimeter, genomic and immunologic

assays, DoE, systems engineering & development, quantitative rt-

PCR, haemocytometer counting, RCA, microarray assays, competent

cell preparation, directed evolution, screen libraries of GMO

mutants, ISO 9000, Cofactor Spec Assay, Tecan

SOFTWARE

Microsoft Office Excel, Word, PowerPoint, Project, Visio,

Access, Empower, Chemstation, Biomek Software, Gemini,

MetaMorph, ImageQuant, Igor, LIMS (Harvester), E-Chip & Design

Expert (DoE Software Packages), VBA, Protein Sequence-Activity

Relationships (ProSAR), Designed Experiments for FX or Tecan

(D.E.F.T), SciFinder

PUBLICATIONS:

Multiplexed SNP genotyping using nanobarcode particle

technology.

Michael Y. Sha, Ian D. Walton, Scott M. Norton, Micah Taylor,

Mark Yamanaka, Michael J. Natan, Chongjun Xu, Snezana Drmanac,

Steve Huang, Adam Borcherding, Radoje Drmanac and

Sharron G. Penn

Anal Bioanal Chem. 2006 Feb;384(3):658-66. Epub 2006 Jan 19.

Microfabricated Templates for the Electrodeposition of Metallic

Barcodes for Use in Multiplexed Bioassays

True, R.J.; Taylor, M.K.; Chakarova, G.S.; Walton, I.D.;

Engineering in Medicine and Biology Society, 2004. EMBC 2004.

Conference Proceedings. 26th Annual International Conference of

the

Volume 1, 1-5 Sept. 2004 Page(s):2619 - 2622 Vol.4

REFERENCES: Available upon request

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