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Research Assitant - Small molecule synthesis/ Enzyme assays

Location:
Richmond, VA
Posted:
January 06, 2014

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Resume:

Malaika Dilip Argade

***, * . ******** **., *** *03, Richmond, VA 23220

Phone: 804-***-****

Email: acb0bm@r.postjobfree.com

Work authorization status: OPT STEM F-1 visa (Do not require sponsorship till Jan. 2015)

Education

Aug 2010 – Aug 2012

Master of Medicinal Chemistry

Virginia Commonwealth University (VCU), Richmond, VA

Aug 2006 – May 2010

Bachelor of Pharmaceutical Sciences

University of Mumbai, India

Research Experience and Seminars

Research Assistant – VCU, Department of Medicinal Chemistry Aug 2012 - present

Synthesis of small molecule potential Anti-depressant

drugs

Masters’ Project – VCU, Department of Medicinal Chemistry Nov 2010 – Aug 2012

Discovery and biophysical characterization of allosteric

inhibitors of enzyme factor XIa (FXIa)

Masters’ seminar – Applications of Liquid chromatography

Mass Spectrometry in chemical and biological Mar 2011

sciences

Bachelor’s Seminar – Resolution of chiral compounds Mar 2009

Work Experience

Aug 2012 – present

Laboratory Technician, Department of Biology, VCU

Responsibilities entail organizing and maintaining a chemical/reagent inventory, preparation

of media, culturing bacteria, preparing aliquots of enzymes and reagents and setting up and

calibrating analytical instruments such as spectrometers and weighing balances .

Teaching Experience

Jan 2013 – May 2013

Adjunct Faculty, Department of Biology, VCU

BIOZ 151 Introductory Biological Sciences Laboratory

Involves organizing and teaching laboratory courses for an average class strength of 25

students. Assistance in developing course materials, examinations and grading assignments,

homework and solutions.

Academic Tutor for pre-medical CERT students and Nurse Anesthetists (VCU)

BIOC/MICR 503 – Biochemistry, Cell and Molecular Biology Aug 2012 – May 2013

MEDC 532 – Medicinal Chemistry for Nurse Anesthesia Jan 2013 – May 2013

Technical Skills

Drug Discovery/Enzyme Kinetics Enzyme kinetics assays and binding studies, High-

Throughput Screening.

Spectroscopy Absorption, Fluorescence, UPLC-MS, IR, Polarimetry,

NMR.

Molecular Biology DNA Isolation, Plasmid miniprep, Bacterial and Yeast

transformation, Agarose Gel Electrophoresis, PCR.

Software Tools SoftMax Pro, sedfit, BioChemDraw, SigmaPlot 11, Reaxys,

MassLynx, SnapGene Viewer, Microsoft Office.

Small Molecule Synthesis Setting up organic chemistry reactions independently and

subsequent work-up. Familiar with extraction and

recrystallization techniques, m.p. determination, pH meter,

Kugelrohr distillation, column chromatography, lyophilizer,

Microwave and sonication based synthesis.

Pharmaceutical Sciences Practical laboratory training and course work in

pharmaceutics, pharmaceutical analysis, organic and

medicinal chemistry, pharmacognosy, biotechnology,

anatomy and physiology and cosmetology.

Poster Presentation and Publication

Argade, M. D.; Mehta, A. Y.; Sidhu, P. S.; Desai, U. R. Inhibition of coagulation cascade enzyme

FXIa by small sulfated molecules”, April 2012. Department of Medicinal Chemistry. Annual

Graduate Student Association Symposium, VCU

Argade, M. D.; Mehta, A. Y.; Desai, U. R. Discovery of small molecule allosteric inhibitors of

coagulation factor XIa. (Publication in preparation)

Extracurricular Activities

Volunteer (Youth Ambassador), Hands on Greater Richmond, Richmond, VA.

Volunteer, Tiranga - Indian Students Association, VCU.

Cultural Secretary, Oriental College of Pharmacy, University of Mumbai, India

Interests include photography, adventure sports and origami

Recommenders:

1. Dr. Malgorzata Dukat, Associate Professor, Department of Medicinal Chemistry, Virginia

Commonwealth University, Richmond VA.

Ph. no. 804-***-****

Email: acb0bm@r.postjobfree.com

2. Dr. Richard A. Glennon, Professor and Chairman of Department of Medicinal Chemistry,

Virginia Commonwealth University, Richmond VA.

Ph. no. 804-***-****

Email: acb0bm@r.postjobfree.com

3. Emily Watkinson, Laboratory Supervisor, Department of Biology, Virginia Commonwealth

University, Richmond, VA.

Ph. no. 804-***-****

Email: acb0bm@r.postjobfree.com

4. Dr. Renata Kolanos, Laboratory Director, Department of Medicinal Chemistry, Virginia

Commonwealth University, Richmond, VA.

Ph. no. 804-***-****

Email: acb0bm@r.postjobfree.com



Contact this candidate