Longxi (Jesse) Xiao, PhD
**** ********* **** **, ******, DE 19711
Cell: 302-***-****, Email: *****@****.***
EDUCATION
Ph.D. Materials Science and Engineering GPA: 3.7/4.0 2007~Aug 2013
University of Delaware, Newark, DE
Dissertation Title: Mechano-Responsive Hydrogels Crosslinked by Self-Assembled Block
Copolymer Micelles
Advisor: Prof. Xinqiao Jia
B.S. Polymer Science and Engineering GPA:3.4/4.0 2004~2007
Fudan University, Shanghai, P. R. China
RESEARCH EXPERIENCE
• Created nanoparticle reinforced thermoplastic polymers for drug delivery application.
• Experienced in the synthesis of polymers using anionic polymerization, emulsion
polyermzation, ATRP, RAFT, ring opening polymerization techniques.
• Expertise in the characterization and analysis of polymers using DSC, TGA, DMA, FT-
IR, NMR, GPC, and et al.
• Rheological studies on polymer fluids, hyaluronic acid hydrogel formation equipped with
UV curing, viscosity measurement on different fluids and model fit.
• Formulated functionalized block copolymer nanoparticle/micelles. Studied self-assembly
and dissociation under external force using TEM, FCS, DLS, Fluorometer, SAXS, and
rheo-SANS.
• Developed drug encapsulation and release vehicles using mechano-responsive hydrogel.
• Synthesized and characterized hydrogels using AFM, SEM, DMA and Confocal
microscopy.
• Cell culture and ELISA study on the cell proliferation and growth factor release.
SKILLS
Synthesis Techniques:
Anionic Polymerization, Emulsion polymerization, Suspension polymerization, Atom Transfer
Radical Polymerization (ATRP), Reversible Addition Fragmentation chain Transfer (RAFT)
polymerization, Ring opening Polymerization, Nanoparticle formulation, Small molecule
synthesis and purification.
Software:
MATLAB, AutoCAD, Autodesk, Chemdraw, Microsoft office, and Materials Studio.
Materials Characterization:
Rheometer, SANS, XPS, SAXS, NMR, GPC, GC, HPLC, MS, DMA, FT-IR, UV-Vis,
Fluorometer, DSC, TGA, DLS, TEM and FCS.
COMMUNICATION SKILLS
• Taught graduate level courses in the department of Materials Science and Engineering
from 2009 to 2012, MSEG630/CHEG600 “Introduction to the science and engineering of
polymer systems” and MSEG833 “Polymer Synthesis and Characterization Laboratory”
• Coauthor on more than 13 publications and speak at national ACS conference annually.
LEADERSHIP & MANAGEMENT SKILLS
• Managed departmental shared facilities (GPC, NMR, FT-IR, DSC, Freeze dryer,
Fluorometer, DMA, Rheometer and UV-Vis Spectrometer);
• Trained junior graduate students on polymer synthesis and characterization;
• Supervised and mentored several undergraduate students on their senior thesis;
• Served as the Chemical Safety Officer in the Department of Materials Science and
Engineering.
ACADEMIC HONORS AND AWARDS
2004 2006
First Class Scholarship, Fudan University
2005 2006
Wangdao Scholar Award, Fudan University
2006 2007
Zhong Hai You Scholarship, Soong Ching Ling Foundation
2009 2010
College of Engineering Excellence in Teaching Award, Univ. of Delaware
Materials Sci & Eng Chairperson’s Outstanding Student Award, Univ. of Delaware 2011 2012
PROFESSIONAL AFFILIATION
2008 present American Chemical Society (ACS), Materials Research Society (MRS)
SELECTED PUBLICATIONS
Peer-Reviewed Journal Publications and Preprints
1 Xiao, L.; Tong, Z.; Chen, Y.; Sabanayagam, C.; Pochan, D.; Jia, X. “Hyaluronic acid
hydrogels crosslinked by reactive block copolymer micelles for anti-inflammatory
application”, Biomacromolecules, 2013, Accepted.
2 Yang, X.; Xiao, L.; Jia, X. "Designing Mechano–Responsive Materials with Elastomeric
Properties for Biomedical Applications" SurFACTS in Biomaterials, 2013, 18, 7-8
3 Gurski, L.A.; Xu, X.; Labrada, L.N.; Nguyen, N.T.; Xiao, L.; van Golen, K.L.; Jia, X.;
Farach-Carson, M.C. “Hyaluronan (HA) interacting proteins RHAMM and hyaluronidase
impact prostate cancer cell behavior and invadopodia formation in 3D HA-based hydrogels”,
PLoS One, 2012, 7(11), e50075.
4 Xiao, L.; Zhu, J.; Pochan, D. J.; Londono, J. D.; Jia, X. “Mechano-Responsive Hydrogels
Synthesized by Block Copolymer Micelles”, Soft Matter, 2012, 8, 102**-*****.
5 Teller, S.; Farran, A.; Xiao, L.; Jiao, T.; Duncan, R.; Clifton, R.; Jia, X. “High Frequency
Viscoelastic Shear Properties of Vocal Fold Tissues: Implications for Vocal Fold Tissue
Engineering”, Tissue Eng. A, 2012, 18, 2008-2019.
6 Xiao, L.; Jia, X. “Novel hydrogels of block copolymer micelles: synthesis, characterization
and application”, Polym. Prepr.2012, 53, 152.
7 Xiao, L.; Jia, X. “Self-assembled nanoparticles derived from diblock and multiblock
copolymers as modular drug delivery vehicles”, Polym. Prepr.2011, 52, 107.
8 Xiao, L.; Liu, C.; Zhu, J.; Pochan, D. J.; Jia, X. “Hybrid, Elastomeric Hydrogels Crosslinked
by Multifunctional Block Copolymer Micelles”, Soft Matter, 2010, 6, 5293-5297.
9 Xiao, L.; Liu, C.; Jia, X. “Mechano-Responsive Hydrogels with Sacrificial Bonds and
Hidden Length”, Polym. Prepr.2010, 51, 244.
10 Grieshaber, S. E.; Xiao, L.; Liu, C.; Jia, X. “Mechano-Responsive Hydrogels via Biomimetic
Approaches”, Polym. Mat. Sci. Eng. Prepr.2010, 102, 318.
11 Xiao, L.; Liu, C.; Jia, X. “Synthesis and Characterization of Mechano-Responsive
Hydrogels”, Polym. Prepr.2009, 50, 652.
12 Wang, X.; Xiao, L.; Jia, X. “Core-Stablized Block Copolymer Micelles for Controlled
Release of Cancer Therapeutics”, Polym. Mat. Sci. Eng. Prepr.2009, 101, 1339
13 Wang, X.; Xiao, L.; Liu, C.; Jia, X. “Block Copolyester Micelles as Nanocarriers for
Sustained Release of Camptothecin”, Polym. Prepr.2009, 50, 349.
PRESENTATIONS AND POSTERS
1. Xiao, L.; Jia, X. “Novel hydrogels of block copolymer micelles: synthesis, characterization
and application”, Oral Presentation, 244th American Chemical Society (ACS) National
Meeting, Philadelphia, PA, August, 2012.
2. Xiao, L.; Liu, C.; Jia, X. “Hybrid, elastomeric hydrogels crosslinked by multifunctional
block copolymer micelles”, Oral Presentation, 242th American Chemical Society (ACS)
Annual Meeting, Boston, MA, August 22-26, 2010.
3. Xiao, L.; Liu, C.; Jia, X. “Synthesis and characterization of Mechano-responsive hydrogels”
Poster Presentation, 241th American Chemical Society (ACS) Annual Meeting, Washington,
DC, August, 2009.
REFERENCES
Xinqiao Jia
PhD, Associate Professor
Department of Materials Science and Engineering, Biomedical Engineering Program
206 DuPont Hall, University of Delaware, Newark, DE 19716
Phone: 302-***-****, Email: ****@****.***
Darrin J. Pochan
PhD, Professor
Department of Materials Science and Engineering, Delaware Biotechnology Institute
207 DuPont Hall, University of Delaware, Newark, DE 19716
Phone: 302-***-****, Email: ******@****.***
Sarah Grieshaber
PhD, Product Technologist
SABIC Innovative Plastics
Evansville, IN, 47711, USA
Phone: 973-***-****, Email: ***************@*****.***