Medical Device Engineering

Pranjali Tambe

**** ***** ***** **** *** **** San diego, CA 92122

Email: ********.*******@*****.***, **************@*****.**.** Phone no: 817-***-****

Objective:

Looking for an opportunity to work with an organization where I can apply my knowledge and experience to

enable personal and professional growth.

Education:

• Master of Science, Bioengineering August 2013

The University Of Texas at Arlington (GPA: 3.4/4.0)

• Bachelor of Engineering, Biomedical Engineering

Gujarat University, India (GPA: 3.5/4.0) June 2011

Work Experience:

Graduate Research Assistant Dec 2011-August 2013

Nanomedicine and Drug delivery lab, University of Texas at Arlington

• Developed and optimized nano/microparticles and hydrogels formulations for cancer and wound healing

• Designed and undertook various cell based studies and assays as well as bacterial studies for drug delivery

and tissue engineering applications maintaining safe and aseptic conditions

• Managed and organized lab supplies while maintaining lab inventory using PROCARD. Ability to follow

safety procedures and work according to the guidelines

• Assisted in grading reports, evaluating graduate students, writing grants and making protocols for the lab.

Duties also included taking guest lectures and mentoring students

• Worked as a team member for several projects simultaneously maintaining a lab notebook, led the team for

certain projects and ability to work in highly competitive environment while managing time and resources

Intern, Apollo International Hospitals Jan 2011- Feb 2011

• Hands on experience with basic rules and mechanisms on medical equipment maintenance, along with active

learning about its diverse electrical components

• Assisted internal team on conducting routine equipment supervisions for safety and efficacy as per standard

protocols

• Developed effective interpersonal and communication skills by acting as a liaison between medical staff and

engineering team members

Summary of skills:

• Nano-micro particles synthesis: Expertise in synthesizing and characterizing polymeric and metallic nano-

micro particles by various techniques

• Polymer synthesis: Hands on experience in synthesis of elastomeric polymers and various hydrogels,

scaffolds and their characterization

• Cell and Bacterial culture: Proficient in culturing and maintaining mammalian and cancer cell lines.

Bacterial culture techniques include making agar plates, broth and various other studies. Media and buffer

preparation

• Biochemical and cell based assays: BCA protein, ELISA, Pico-green DNA, MTS, Iron assay, LIVE/DEAD

staining, Immunostaining and Imaging, Fluorescence cell imaging, Trypan blue, Pharmacokinetic and

viability studies, Plasmid Isolation, RNA Isolation

• Instruments and Characterization techniques: SEM, TEM, FTIR, DLS, pipetting, Spectrophotometer (UV-

Vis) (Tecan), Cytoviva optical microscope, Confocal microscopy, Flexcell, Ultracentrifuge, Sonicator, Gel

electrophoresis, Zeta potential analyzer (Zeta-Pal)

• Software: Microsoft office suite, Endnote, Design of experiments, ImageJ, Photoshop, Statistical analysis

(SAS, Statview), MATLAB, Labview, AVR studio, Filterpro

Projects:

Nanocomposite hydrogel system for melanoma skin cancer treatment and subsequent wound healing

• Synthesized and optimized a novel injectable system for wound healing and skin cancer treatment

• Characterized pH-sensitive nanoparticles for sustained release of two cancer drugs

• Conducted various studies including drug release, degradation and various in-vitro studies

• Conjugated peptides to the hydrogel for anti-bacterial properties

To investigate HASMC (Human aortic smooth muscle cell) responses towards stretch stimuli and various

factors (Funded by American Heart Association)

• Investigated the effects of biomechanical factors like stretch on HASMC responses like their alignment and

proliferation for diseases like atherosclerosis, diabetes and obesity

• Biochemical factors were also examined like growth factors, low density lipoprotein and glucose

• This project was undertaken by a novel system known as Microwell Array stretch system (MASS)

To synthesize, characterize and compare BPLP-MNP's and BPLP-Gd nanoparticles and their applications

• Successfully characterized nanoparticles and compared them for their fluorescence for in-vivo imaging, drug

release profile, degradation and application for prostate cancer by conducting in-vitro studies on PC3 cell line

Designing an Electro-oculogram controlled mouse

• Designed an electro-oculogram biopotential amplifier that captures physiological signals from the eye

movements and controls the cursor movements accordingly

Publication:

• Menon JU, Jadeja P, Tambe P, Vu K, Yuan B, Nguyen KT. Nanomaterials for Photo-Based Diagnostic and

Therapeutic Applications. Theranostics 3 (3), 152-166.

• Tambe P, Jadeja P, Kadapure T, Hao X, Nguyen KT. To investigate HASMC (Human aortic smooth muscle

cell) responses towards stretch stimuli and various factors (Funded by American Heart Association) (In

process)

Paper and Poster presentations:

• Pranjali Tambe, Jyothi Menon, Jian Yang, Kytai Nguyen. Nanocomposite hydrogel system for skin cancer

treatment and subsequent wound healing. (Poster presentation- First Annual Texas Medical Device

Symposium, Conference Center, UTD 2012)

• Pranjali Tambe, Jyothi Menon, Jian Yang, Kytai Nguyen. Nanocomposite hydrogel system for skin cancer

treatment and subsequent wound healing. (Poster presentation- 2013 UTD Metroplex Day)

• Pranjali Tambe, Jyothi Menon, Jian Yang, Kytai Nguyen. Nanocomposite hydrogel system for skin cancer

treatment and subsequent wound healing. (Poster presentation- ACES 2013 UTA)

Related coursework:

• Drug Delivery and Nanomedicine/Tissue Engineering

• Neural Engineering

• Biostatistics

• Bioinstrumentation

• Biomaterials/Polymers

• Human Anatomy and Physiology

References:

Available upon request

Contact this candidate