BioMEMS

KANG KUG LEE

*** ****** ****** **** **. W, B** E-mail:***.*******@*****.***

Cincinnati, Ohio, USA, 45220 Mobile: 513-***-****

EDUCATION

Ph.D. Electrical Engineering Sep. 2006 - Expected Dec. 2013 (Final Defense: Jun. 27, 2013)

Department of Electrical Engineering & Computing Systems, University of Cincinnati

Dissertation: "A Sample-to-Answer Polymer Lab-on-a-Chip with Superhydrophilic Surfaces

using a Spray Layer-by-Layer Nano-Assembly Method"

University Graduate Scholarship (Sep. 2006 - Present)

University Research Council (URC) Summer Fellowship Award (2008)

M.S. Mechanical Engineering Sep. 2003 - Jun. 2005

School of Mechanical & Aerospace Engineering, Ohio State University

Thesis: "Surface Modification of Silicon and PDMS surfaces with Vapor Phase Deposited

Ultrathin Fluoropolymer and Fluorosilane Films for Biomedical

Micro/Nanoelectromechanical System Applications"

Engineering Fellowship (Sep. 2003 - Jun. 2005)

M.S. Materials Engineering Mar. 1998 - Feb. 2000

School of Materials Engineering, Hanyang University (Korea)

Thesis: "Chemical, Optical and Mechanical Characterization of Perfluoropolymer Thin Films as an

Anti-stiction Layer in Micro-Electro-Mechanical Systems (MEMS)"

National Research Laboratory (NRL) Graduate Fellowship Award (Mar. 1998 - Feb. 2000)

B.S. Materials Engineering Mar. 1988 - Feb. 1992

School of Materials Engineering, Hanyang University (Korea)

University Scholarship (Mar. 1989 - Sep. 1991)

WORK EXPERIENCE

Graduate Research Assistant Sep. 2006 - Present

Department of Electrical Engineering & Computing Systems, University of Cincinnati

Research Engineer Jan. 2006 - Jun. 2006

School of Biomedical Engineering, Ohio State University

Graduate Research Assistant Sep. 2003 - Jun. 2005

School of Mechanical & Aerospace Engineering, Ohio State University

Instructor Sep. 2000 - Jun. 2003

Private Academic Institute for high school students (Korea)

Student Internship Mar. 1998 - Feb. 2000

Center for Electronic Materials and Components, Samsung Electronics Co. (Korea)

Graduate Research Assistant Mar. 1998 - Aug. 2000

School of Materials Engineering, Hanyang University (Korea)

PROFESSIONAL ACTIVITIES

Journal Referee

Review journal articles for Lab on a Chip, ACS Applied Materials & Interfaces, RSC Advances,

and RSC Analytical Methods.

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KANG KUG LEE (continued)

RESEARCH EXPERIENCE

Research Assistant Sep. 2006 - Present

Department of Electrical Engineering & Computing Systems, UC

Developed a sample-to-answer microfluidic lab-on-a-chip for point-of-care clinical diagnostics

Developed a new on-chip blood plasma separator using asymmetric capillary force

Developed a microfluidic lab-on-a-chip analytical device using colorimetric assay

Integrated the on-chip blood plasma separator with the microfluidic lab-on-a-chip

analytical device toward a sample-to-answer microfluidic lab-on-a-chip

Developed MEMS-based microfluidic platform for microenvironment control to solve some

fundamental and applied problems in Neurospora Crassa (co-operative research with Dr. Chris I.

Hong in the department of Molecular and Cellular Physiology at UC)

Developed a microfluidic platform using PDMS

Developed a gas perturbation system with the microfluidic platform for employing the

real-time gas perturbations

Developing a spiral structure for the single cell study in Neurospora Crassa

Created a new on-chip blood plasma separator using asymmetric capillary force;

Demonstrated blood plasma separation with human whole blood

Developed a novel spray layer-by-layer nanoassembly method;

Demonstrated surface-modified superhydrophilic microchannels on thermoplastics

Developed on-chip microfluidic ion-selective potentiometric sensing platform for BioMEMS &

environmental applications

Developed on-chip self-assembly nanobead packed membranes for BioMEMS & environmental

applications

Research Engineer Jan. 2006 - Jun. 2006

School of Biomedical Engineering, Ohio State University

Developed a biodegradable Poly(D,L-lactic acid) (PLA) nanoparticle-based imaging agent for

targeting breast cancer markers toward advanced ultrasonic contrast generation

Research Assistant Sep. 2003 - Jun. 2005

School of Mechanical & Aerospace Engineering, Ohio State University

Developed a vapor phase deposition system designed for the uniform, conformal and ultrathin

coatings of fluoropolymer and fluorosilane thin films inside silicon nanochannels and

characterized the surface properties using atomic force microscopy

Student Internship Mar. 1998 - Feb. 2000

Center for Electronic Materials and Components, Samsung Electronics Co. (Korea)

Developed and demonstrated a vapor phase deposition system for the fluorocarbon thin films in

MEMS-based micromirror arrays.

Cleanroom experience & characterization skills; semiconductor processing, especially, surface

modification and characterization in MEMS devices.

Research Assistant Mar. 1998 - Aug. 2000

School of Materials Engineering, Hanyang University (Korea)

Developed the fluorocarbon thin films for preventing the stiction problem brought in the

actuation of micromirror arrays by a vapor phase deposition system; successfully characterized

the films on the surfaces of micromirrors chemically, optically, and mechanically.

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KANG KUG LEE (continued)

INVOLVED

Novel Smart Catheter for Multimodal Monitoring of the Head-Injured Warrior

Department of Defense, Project No. PT090526P4 (W81xwh-10-1-0978), 2010 – 2015;

Department of Electrical Engineering & Computing Systems, UC

Research advisor: Prof. Chong H. Ahn & Dr. Chunyan Li

Development of a Portable Multi-analyte Sensor to Simultaneously Measure Chloride, Sulfate,

Potassium, ORP and pH in RO Membrane Systems

Gwangju Institute of Science and Technology, KOREA, Grant No. 1006054, 2008 – 2009;

Department of Electrical Engineering & Computing Systems, UC

Research advisor: Prof. Chong H. Ahn & Dr. Am Jang

The Imaging Breast Cancer Markers with Nanoparticle Enhanced Ultrasound

Susan G. Komen Breast Cancer Foundation, Tracking ID No. BCTR0503594, 2006; School of

Biomedical Engineering, OSU

Research advisor: Prof. Jun Liu

The Development of Vapor Phase Deposited Fluorosilane Films for Biomedical Nanodevices

National Science Foundation, Contract No. ECS–0301056, 2004 – 2005; School of Mechanical

Engineering, OSU

Research advisor: Prof. Bharat Bhushan & Prof. Derek Hansford

The Prevention of Stiction in Micromirrors & The Development of Reliable FC Organic Films

Samsung Electronics Co., KOREA, 1998 – 2000; School of Materials Engineering, Hanyang

University (Korea)

Research advisor: Prof. Jin-Goo Park

The Development of Inductor Using CMP Processes

Korea Science and Engineering Foundation, KOREA, 1999 – 2000; School of Materials

Engineering, Hanyang University (Korea)

Research advisor: Prof. Jin-Goo Park

The Development of Hot DI Water Generator

Ansan City, KOREA, 1998 – 1999; School of Materials Engineering, Hanyang University

(Korea)

Research advisor: Prof. Jin-Goo Park

TEACHING EXPERIENCE

Jan. 2012 – Present

Research Advisor

Department of Electrical Engineering & Computing Systems, UC

Supervised undergraduate students and graduate students performing surface modification with

spray layer-by-layer nanoassembly method for biomedical applications

Jan. 2008 – Mar. 2008

Graduate Teaching Assistant & Part-time Instructor

Department of Electrical Engineering & Computing Systems, UC

ECE641: Silicon Semiconductor Microfabrication Lab for MEMS

Supervised undergraduate and graduate students performing the semiconductor microfabrication

using cleanroom facilities at UC

Research Advisor Mar. 1999 - Jun. 2000

School of Materials Engineering, Hanyang University (Korea)

Supervised undergraduate students and graduate students performing surface modification of the

fluorocarbon thin films for preventing the stiction problem on the surfaces of micromirrors by a

vapor phase deposition system

Grader Mar. 1999 - Jun. 2000

Semiconductor Processing, Hanyang University (Korea)

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KANG KUG LEE (continued)

PUBLICATIONS

Refereed Journal Articles & Conference Proceedings:

20. Kang Kug Lee (Corresponding author) and Chong H. Ahn, “A Whole Blood Sample-to-Answer

Lab-on-a-Chip with Asymmetric Capillary Force Based Blood Plasma Separator,” The 27th

International Conference on Micro Electro Mechanical Systems (MEMS 2014), January 26 – 30,

2014, San Francisco, USA (submitted).

19. Kang Kug Lee (Corresponding author) and Chong H. Ahn, “A New On-Chip Whole Blood/Plasma

Separator Driven by Asymmetric Capillary Forces,” Lab on a Chip, vol. 13, pp. 3261 – 3267, 2013.

18. Kang Kug Lee (Corresponding author) and Chong H. Ahn, “Superhydrophilic Multilayer Silica

Nanoparticle Networks on a Polymer Microchannel Using a Spray Layer-by-Layer Nanoassembly

Method,” ACS Applied Material & Interfaces, vol. 5(17), pp. 8523 – 8530, 2013.

17. Kang Kug Lee, Chong H. Ahn, Christian I. Hong, “Circadian Rhythms in Neurospora Crassa on

Polydimethylsiloxane Microfluidic Device for Real-time Gas Perturbations,” Biomicrofluidics, vol.

7, pp. 044129–1 – 044129–7, 2013.

16. Kang Kug Lee, Chong H. Ahn, Christian I. Hong, “Circadian Rhythms in Neurospora Crassa on a

Microfluidic Device for Real-time Gas Perturbations,” The 17th International Conference on Solid-

State Sensors, Actuators and Microsystems (Transducers 2013 & Eurosensors XXVII), June 16 –

20, 2013, Barcelona, Spain, pp. 1247–1250.

15. Kang Kug Lee (Corresponding author) and Chong H. Ahn, “A New Asymmetric Capillary Force

Driven Whole Blood/Plasma Separator using Spray Layer-by-Layer Nano-Assembly,” The 16th

International Conference on Miniaturized Systems for Chemistry and Life Sciences ( TAS 2012),

October 28 – November 1, 2012, Okinawa, Japan, pp. 1936 – 1938.

14. Kang Kug Lee (Corresponding author) and Chong H. Ahn, “Nanoporous-based hydrophilic

polymer channel using a spray layer-by-layer electrostatic nano-assembly,” Hilton Head

Workshop 2012: Solid-State Sensors, Actuators, and Microsystems Workshop, June 3 – 7, 2012,

Hilton Head Island, SC, USA, pp. 209 – 212.

13. Am Jang, Kang Kug Lee, Paul L. Bishop, Insu Kim, Chong H. Ahn, “Development of polymer lab-

on-a-chip (LOC) for oxidation-reduction potential (ORP) measurement,” Water Science and

Technology, vol. 63, No. 10, pp. 2309 – 2315, 2011.

12. Am Jang, Zhiwei Zou, Kang Kug Lee, Chong H. Ahn, Paul L. Bishop, “State-of-the-art lab chip

sensors for environmental water monitoring,” Measurement Science and Technology, vol. 22, No.

032001, pp. 1 – 18, 2011.

11. Am Jang, Zhiwei Zou, Kang Kug Lee, Chong H. Ahn, Paul L. Bishop, “Potentiometric and

voltammetric polymer lab chip sensors for determination of nitrate, pH and Cd(II) in water,”

Talanta, vol. 83(1), pp. 1 – 8, November, 2010.

10. Kang Kug Lee, Am Jang, Michael J. Rust, Paul L. Bishop, Chong H. Ahn, “Self-Assembly

Nanobead-Packed Hetero Columns for pH and Nitrate Ion-Selective Sensors,” The 13th

International Conference on Miniaturized Systems for Chemistry and Life Sciences ( TAS 2009),

November 1 – 5, 2009, Jeju Island, Korea, pp. 1632 – 1634.

9. Andrew W. Browne, WooSeok Jung, Kang Kug Lee, SeHwan Lee, Jaephil Do, Chong H. Ahn,

“Rapid Point of Care (POC) Blood Analysis using Integrated Dynamic Blood Separation and

Sandwich Immunoassay on a Polymer Lab Chip,” The 12th International Conference on

Miniaturized Systems for Chemistry and Life Sciences ( TAS 2008), October 12 – 16, 2008, San

Diego, CA, USA, pp. 417 – 419.

8. Bharat Bhushan, Derek Hansford, Kang Kug Lee, “Surface modification of silicon and

polydimethylsiloxane surfaces with vapor-phase-deposited ultrathin fluorosilane films for biomedical

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KANG KUG LEE (continued)

nanodevices,” Journal of Vacuum Science and Technology A, vol.24(4), Jul/Aug, pp.1197 – 1202,

2006.

7. Kang Kug Lee, Bharat Bhushan, Derek Hansford, “Nanotribological characterization of

fluoropolymer thin films for biomedical micro/nanoelectromechanical system applications,” Journal

of Vacuum Science and Technology A, vol. 23(4) Jul/Aug, pp. 804 – 810, 2005.

6. Kang Kug Lee, Nam-Goo Cha, Joon-Sung Kim, Jin-Goo Park, Hyung-Jae Shin, “Chemical, Optical

and Tribological Characterization of Perfluoropolymer Films as an Anti-stiction Layer in Micro-

mirror Arrays,” Thin Solid Films, vol. 377-378, pp. 727 – 732, 2000.

5. Jun-Sung Kim, Nam-Goo Cha, Kang Kug Lee, Jin-Goo Park, Hyung-Jae Shin, “Characterization of

Fluorocarbon Thin Films by AFM/LFM and Contact Angle Measurements,” Journal of the

Microelectronics and Packaging Society, vol. 7, No. 1, pp. 35 – 40, 2000.

4. Nam-Goo Cha, Joon-Sung Kim, Kang Kug Lee, Jin-Goo Park, Hyung-Jae Shin, “Atomic/Lateral

Force Microscopy Measurements of Anti-sticking Layer in Micro-Electro-Mechanical Systems

(MEMS),” The 2nd Korean MEMS Conference, April 14 – 15, 2000, KAIST, Korea.

3. Kang Kug Lee, Jin-Goo Park, Hyung-Jae Shin, “The Characterization of Optical Properties of

Fluorocarbon Polymer Thin Films on Silicon Substrate by a Variable Angle Spectroscopic

Ellipsometry,” Materials Research Society Symposium, Fall Meeting, November 29 – December 3,

1999, Boston, MA, USA, vol. 588, pp. 297 – 302.

2. Dae-Hong Eum, Sang-Yong Kim, Kang Kug Lee, Ki-Sub Kim, Hyung-Soo Song, Jin-Goo Park, “

The Reaction of H2O2 and Ozone in Ammonium Hydroxide (NH4OH) solutions with Silicon Wafers,”

The 1999 Joint International Meeting of the Electrochemical Society, October 17–22, 1999,

Honolulu, Hawaii, USA, vol. 99 – 36, pp. 288 – 295.

1. Jin-Goo Park, Myong-Jong Kwon, Kang Kug Lee, Yong-Kweon Kim, Hyung-Jae Shin, “ The Vapor

Phase Deposition of Fluorocarbon Films for the Prevention of In-use Stiction in Micromirror”,

Japanese Journal of Applied Physics, vol. 37, No. 12B, pp. 7058 – 7063, 1998.

Conference presentations:

11. Am Jang, Kang Kug Lee, Se Hwan Lee, Chong H. Ahn, and Paul L. Bishop, “Development of

Disposable Microfabricated Chip Sensor Using Nano Bead Packing Method to Measure ORP,”

International Environmental Nanotechnology Conference: Applications and Implications, October

7 – 9, 2008, Chicago, IL, USA.

10. Kang Kug Lee, Bharat Bhushan, Derek Hansford, “Nanotribological characterization of

perfluoropolymer thin films for BioMEMS applications,” NLIM Annual Review, The Ohio State

University, September 20 – 21, 2004, Columbus, OH, USA.

9. Joon-Sung Kim, Nam-Goo Cha, Kang Kug Lee, Jin-Goo Park, “Characterization of

Perfluoropolymer Thin Films grown by Pulsed PECVD,” Material Research Society of Korea,

Spring Meeting, May 19 – 20, 2000, Jeonnam University, Korea.

8. Kang Kug Lee, Nam-Goo Cha, Joon-Sung Kim, Jin-Goo Park, Hyung-Jae Shin, “Chemical, Optical

and Tribological Characterization of Perfluoropolymer Films as an Anti-sticking Layer in Micro-

mirror Arrays,” International Conference on Metallurgical Coatings and Thin Films, April 10 –

14, 2000, San Diego, CA, USA.

7. Kang Kug Lee, Jin-Goo Park, Yong-Kweon Kim, Hyung-Jae Shin, “Optical Properties of

Fluorocarbon Thin Films on Aluminum Top Layers in Micro-mirror Arrays,” The 1st Korean MEMS

Conference, April 17, 1999, KAIST, Korea.

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KANG KUG LEE (continued)

6. Myong-Jong Kwon, Kang Kug Lee, Jin-Goo Park, “The Vapor Phase Deposition of Fluorocarbon

Organic Thin Films and its Characterization,” The International Microelectronics and Packaging

Society of Korea, Fall Meeting, November 14, 1998, Hanyang University, Korea.

5. Kang Kug Lee, Myoung-Jong Kwon, Jin-Goo Park, “Determination of Thickness and Optical

Properties of FC Thin Film on Al by a Variable Angle Spectroscopic Ellipsometry,” Material

Research Society of Korea, Fall Meeting, November 6, 1998, Kuk-Min University, Korea.

4. Nam-Goo Cha, Kang Kug Lee, Jin-Goo Park, Hyung-Jae Shin, “Characterization of

Perfluoropolymer Thin Films on TEOS Deposited by Thermal Evaporation,” The International

Microelectronics And Packaging Society of Korea, Fall Meeting, November 12, 1999, Hanyang

University, Korea.

3. Nam-Goo Cha, Kang Kug Lee, Jin-Goo Park, Hyung-Jae Shin, “The Deposition of Fluorinated Thin

Films by Thermal Evaporation and PECVD,” Material Research Society of Korea, Fall Meeting,

November 5, 1999, Inha University, Korea.

2. Kang Kug Lee and Jin-Goo Park, “Optical Modeling of Fluorocarbon Polymer Thin Films on Silicon

Substrate,” Material Research Society of Korea, Spring Meeting, May 14 – 15, 1999, KumHo

University, Korea.

1. Nam-Goo Cha, Kang Kug Lee, Jin-Goo Park, “Characterization of Fluorocarbon Thin Films by

Contact Angle Measurements,” Material Research Society of Korea, Spring Meeting, May 14 – 15,

1999, KumHo University, Korea.

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