Babak Behnam, PhD

http://orcid.org/****-****-**66-1602, https://www.linkedin.com/in/babakbehnam

ac9dox@r.postjobfree.com ac9dox@r.postjobfree.com Cell: 407-***-****

Citizenship: USA

EDUCATION and ACADEMIC ACTIVITIES/POSITIONS:

July 2018- Research Volunteer Fellow, ABMGG board review, finalizing the results of

Present translational research, Undiagnosed Diseases Program (UDP) Translational Laboratory / manuscript preparations, NHGRI, NIH, Bethesda, Maryland, USA

Jan. 2016- Biologist/Research Scientist, UDP Translational Laboratory- recruiting molecular

July 2018 biology techniques (DNA/RNA purification, PCR, RFLP, making constructs and mutagenesis, bacterial transformation/culture, cell lines transfections, proteomics techniques/WB, …) to assay and manipulate human fibroblasts and mice cell lines

Clinical Biochemical Genetics Fellow (ABMGG-accredited), NHGRI, NIH, Bethesda, Maryland, USA

July 2009 - Assistant/Associate Professor of Human Genetics, Department of Medical

Dec. 2015 Genetics and Molecular Biology, Faculty of Medicine;

Director, Medical Genetics Laboratory, OB/G and Children University Hospital

Iran University of Medical Sciences (IUMS), Tehran, Iran

Oct. 2006 - Postdoctoral Research Associate, Burnett School of Biomedical Sciences, College

June. 2009 of Medicine, University of Central Florida, Orlando, FL, USA

Aug 2005 - NIH-based NRSA (National Research Service Award) Post-doctoral

Sep 2006 Research Fellowship, Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA

Jan-July Post-doc fellowship, Department of Cell and Developmental Biology,

2005 University of Michigan Medical School, Ann Arbor, MI, USA

2001-2005 PhD in Human Genetics, University College London (UCL), London, UK

2000-2001 MSc in Molecular Medicine, Department of Molecular Medicine, University of Sheffield, Sheffield, UK

1997-2000 General Physician & Research Coordinator, Department of Research Affairs, Tehran University of Medical Sciences (TUMS), Tehran, Iran

1989-1997 Medical Studentship (leading to MD), Iran University of Medical Sciences, School of Medicine, Tehran, Iran (GPA: 3.4, National License # 63124)

Professional Experiences & Skills

-Translational and Clinical Research, Medical Scientist; Projects Leader

-Experience working with relevant genomic databases and browsers and their annotations (NCBI, Refseq, Ensembl, ClinVar, HGMD, gnomAD, CADD, IGV, UCSC Genome Browser)

-Research Strategy Determination; Clinical Studies Management; Scientific Claim validation

-Publications & Authorship in > 50 peer-reviewed articles in highly cited scientific journals (in 13 years)

Molecular Cell biology techniques- DNA & RNA extraction form animal tissue and cells, PCR, RT-PCR, Q-

PCR, Mutagenesis. Confocal microscopy, construct formation and sub-cloning

Internal regulatory requirement in Clinical Trials and drug candidate production/manufacture- Participated in several GMP Trainings for various clinical phases

Biochemical Genetics Tests: - Acylcarnitine/Acylglycine profiles Assays - Organic Acid Analysis

- Carrier testing - Newborn screening - Quantitative Amino Acid Analysis

- Management & Care - Prenatal Diagnosis - Enzyme assay - GMAT & Other tests

Molecular genetics analyses of about 75 most common diseases among the population; reported ~ 800

molecular genetics tests (cases) and ~ 85 PNDs

Cytogenetic and Karyotype analyses

Genomics and proteomics Variants classification and analyses via different in silico tools and soft-wares

Proteomics techniques- MALDI-TOF, LC-MS-MS, GC-MS, Plasma/Urine extraction for different protocols of

Organic acid/Amino acid analysis via MS Chromatography, 1D & 2D-PAGE, whole gel electro-elution, multi-elution, Western blotting, affinity chromatography

Tissue culture techniques

Immunological techniques- flow cytometry, ELISPOT, cytotoxic T cell assay, ELISA, WB, dot blot, raising

antibodies, purification of antibodies, immuno-histo/cyto-chemistry, and immunofluorescence

Microbiology techniques – Bacterial and Yeast cultures, colony forming units (CFU) enumeration etc.

Handling of experimental animals like-Mice and Guinea pigs.

PROFESSIONAL ORGANIZATIONS:

Member, Metabolomics Association of North America (MANA) (2018-2019)

Member, American Society of Human Genetics (2016-2018)

Member, Metabolomics Association of North America (2018)

Member, American College of Medical Genetics (ACMG) (2011-2014)

Member, Society for Neuroscience (2007-2008)

Member, Society of Cell and Developmental Biology (2006)

Member, European Society of Human Genetics (2003-2004)

Member, American Society of Human Genetics (2004)

Member, Biochemical Society (2003-2004)

TEACHING EXPERIENCES:

- Human Genetics & Cancer Genetics; for MSc and PhD students in Human Genetics

- Medical Genetics; for medical students and MSc students of Midwifery and Speech Therapy

- Advanced Molecular and cellular sciences; for MSc students in Biochemistry and Biophysics

- Molecular Mechanisms of Diseases; for PhD students in Molecular Medicine

- Molecular Genetics; for PhD students in Anatomy and Immunology

- Genetics Engineering; for MSc students in Biotechnology

REVIEW AND ADVISORY PANELS:

Peer Review for many scientific journals in Biology, Life Sciences, and Medical Genetics including:

Tumor Biology, Genomics, International Journal of Surgery Case Reports (IJSCR), SCIMETR, European Journal of Inflammation, Medical Journal of the IR Iran (MJIRI), Iranian Journal of Neuroscience, Iranian Journal of Ophthalmology, World Journal of Pediatrics, Journal of Current Ophthalmology

HONORS and AWARDS

2008 CNS Tumor Section, Brain Lab Community Neurosurgery Award Congress of

Neurological Surgeons; Annual meeting 2008, Florida, USA

2008 Included in Who's Who in America, 2008 Edition.

2005 NIH-based Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Research Fellowship; U Michigan, MI, USA

2000 Japanese Young Scientist Award, University of Nagoya Medical Center, Japan, XXIII

International Congress of the International Academy of Pathology

2000 Full Scholarship by (MHME) to pursue a PhD degree in Genetics, [2001-2005]

PRESENTATION & MEETINGS

2017 The American Society of Human Genetics (ASHG), 67th Annual meeting, Orlando, Florida

2016 The American Society of Human Genetics (ASHG), 66th Annual meeting, Vancouver, Canada

2016 Rare Disease Day at NIH, National Institute of Health, Feb. 29, 2016, Bethesda, MD

2015 1st International Conference on Transcriptomics, July 27-29, 2015 Orlando, FL, USA

2014 American College of Medical Genetics, 23rd Annual meeting 2014, Nashville, TN, USA

2013 American College of Medical Genetics, 22nd Annual meeting 2013, Phoenix, AZ, USA

2012 American College of Medical Genetics, 21st Annual meeting 2012, Charlotte, NC, USA

2011 Inetrnational Society of Ocular Oncology (ISOO), Biannual meeting 2011, Buenos Aires, Argentina

2011 American College of Medical Genetics, 20th Annual meeting 2011, Vancouver, Canada

2008 Congress of Neurological Surgeons. Annual meeting 2008, Orlando, Florida, USA

2007 AANS - CNS Annual meeting, Miami, Florida, USA.

2007 1st International Brain Conference, Orlando, Florida, USA

2006 Annual meeting Society of Cell and Developmental Biology, Ann Arbor, MI

2004 The American Society of Human Genetics (ASHG), 54th Annual meeting, Toronto, Canada

2004 The European Society of Human Genetics (ESHG), Annual meeting, Munich, Germany

2003 The European Society of Human Genetics (ESHG), Annual meeting, Birmingham, UK

2002 Germ Cell meeting, Cold Spring Harbor Laboratory, New York, USA

2000 World Conference on Clinical Pharmacology and Therapeutics IUPHAR. European Association for

clinical Pharmacology and Therapeutics (EACPT), Florence, Italy, CPT

1998 International Academy of Pathology, Nice, France

BOOK

1. M. Araghi-Niknam, B. Behnam, S. Hosseini, R.R. Watson, Dehydroepiandrosterone (DHEA) and AIDS (chapter 13 of the ‘Health Promotions and Aging: The Role of Dehydroepiandrosterone (DHEA)). 1st ed., Harwood Academic Publishers, Amsteldijk, 1999.

2. B. Behnam, H. Fazilaty, A. Roghanian, The Importance of Circulating Tumor Cells and Tumor Models in Future of Cancer Therapy (DOI: 10.1007/978-3-319-45397-2_7 In book: Ex Vivo Engineering of the Tumor Microenvironment, pp.121-135). 1st ed., Springer International Publishing, Puducherry, 2017.

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