Pharmacy, Academics, Scientist, Research and Development

RESUME

NAME: S.H.SEYED MOHAMED BUHARY

ADDRESS:

*******@*****.*** ********@**********.***

Whatsapp :+917*********

Sono Vision, 324-A, Courtallam Road, Opp. Thaibala Theatre, Tenkasi, Tirunelveli Dist,

Tamil Nadu - 627759, India

Mobile: 009***********

OBJECTIVE

" A clear focus to achieve excellence in the line of work where I can put my scientific and human skills into action to achieve the organizational and personal goals"

PROFESSIONAL EXPERIENCE

Alfarraj Polyclinic, Alfarraj Pharmacy, Makkah, Saudi Arabia.

Pharmacist from Feb 2013 – Feb 2019, Finished Contract)

(Saudi Prometric Exam Cleared and got license)

Reviews and interprets physician’s drug orders for clarity, rationality, dosage form etc., Answers physician inquiries regarding drugs.

Maintains control and security of all drugs including dispensing, record keeping and secured storage of medications.

Dispenses outpatient’s prescriptions.

Provides drug information to medical staff.

Verifying instructions from physicians on the proper amounts of medication to be given to patients.

Instruct patients on how and when to take a prescribed medicine

Advice patients about general health topics

Oversee the work of pharmacy technicians and pharmacists in training.

ACADEMIC EXPERIENCE

SB College of Pharmacy, Sivakasi, Tamilnadu, India

Associate Professor in Pharmaceutics since Dec 2009 – May 2012

Teaching Industrial Pharmacy for post graduates & guiding for project work.

Guided 9 post graduates (M.Pharm) with Industrial Project.

Participated in UGC Networking Training Programme - UIPS, Panjab University, Chandigarh (29 March – 3 April 2010)

INDUSTRIAL EXPERIENCE

Dr. Reddy’s Laboratories, Hyderabad, India

Assistant Manager in Formulation Research & Development from Sep 2007 – Oct 2009

Handling team in Generics (Solid orals) US Market, Complex solid oral dosage forms.

Development of difficult generic dosage forms for regulated markets.

Strategy for overcoming blocking patents for generic programs.

Strides Technology and Research (STAR), Strides Arcolab limited, Bangalore, India

Sr. Executive in Formulation Research & Development from Dec 2004 – Sep 2007

Handled projects (Solid orals) for KV Pharmaceuticals, US.

Launch of commercial projects through cross functional team comprising of Supply chain, Regulatory, Analytical development, Bioequivalence establishment, Technology transfer and Packaging development

Sun Pharma Advanced Research Centre (SPARC), Sun Pharmaceutical Industries Ltd., Baroda, Gujarat, India (May 2001– Dec 2004)

Research Officer in Formulation Research & Development from May2003 – Dec 2004

Research Assistant in Formulation Research & Development from May2001 – May 2003

Formulation Development of ANDA – US Market (Solid orals) -Generic Product drug development from Preformulation, Strategy making, Prototype development, Scaling up, Submission batches, Product filing, and supporting for commercial product launch.

Development of generic solid oral products from development to bioequivalence establishment and technology transfer for US/EU regulatory filings.

Product launch for Indian Market

Development challenges like matrix extended release product against RLD utilizing deliquescent nature of high dose API to develop extended release drug product on matrix extended release apart from general molecules and drug products.

Process technologies – Fluid bed processing, Bioavailability enhancement techniques, discriminatory dissolution.

Madras Analytical Research and Laboratories (MARAL), Chennai, India

Trainee- Production Chemist in Pharmaceutical Production from July 98 – July 99

PATENTS (US)

Pharmaceutical compositions comprising conjugated estrogens.

Pub. No.: US2009/0232897A1, Pub. Date: Sep. 17, 2009, Filed- March 13, 2009

Fenofibrate Formulations - Pub. No.: US2009/0202649 A1, Pub. Date: Aug. 13, 2009

RESEARCH EXPERIENCE

Tabletting Technology including Delayed Release and Extended Release Tablets (Matrix, Coating, etc.)

Tablet Coating Technology

Scale up of Delayed Release and Extended Release Tablets

Capsule Dosage Formulation

ANDA Projects

Patent Survey

Patent Non Infringing Formulation in Generic Drugs

Tablet and Capsule Dosage Formulations

Dossier Preparation

PUBLICATIONS

S.Jeganath, S. Palanichamy, S.H.Seyed Mohamed Buhary, P.Solairaj, C. Prabhu, A.ThangaThirupathi, Formulation and Evaluation of Silymarin Controlled Release Tablets. Research Journal of Pharmacy and Technology. 3 (3): 927 – 930 (2010).

C. Prabhu, S. Palanichamy, M.Rajesh, P.Solairaj, SHSM Buhary, S.Jeganath and A.T. Thirupathi, Formulation and Evaluation of Theophylline Fast Dissolving Tablets. The Indian Pharmacist. 8 (11): 75 -79 (2010).

S.Jeganath, S. Palanichamy, S.H.Seyed Mohamed Buhary, M. Rajesh, C. Prabhu, A.ThangaThirupathi, Preparation of Silymarin Controlled Release Tablets using Natural Gums and their Evaluation Studies. International Journal of Pharmaceutical Science and Nanotechnology.4 (1): 1368 - 1372 (2011).

M.Rajesh, KamarapuNagaraju, S.H.Seyed Mohamed Buhary“Formulation and Evaluation of Clarithromycin Immediate Release Film Coated Tablets’’, International Journal Of Pharmacy and Pharmaceutical Sciences, 4 (5) : 352 - 357 (2012).

PROJECT UNDERTAKEN

COMPUTER AIDED DESIGN & OPTIMIZATION OF HYDROPHILIC MATRIX TABLETS OF VERAPAMIL HYDROCHLORIDE.

as a dissertation work of M.Pharm. III Sem. Project.

SUPERVISED BY : Dr. S.C.Chaturvedi, Prof & Head,

Dept of Pharmacy, S.G.S.I.T.S.,

Indore., India

CO-SUPERVISED BY : Dr. Bhupinder Singh Bhoop,

Professor in Pharmaceutics,

PanjabUniversity, Chandigarh, India

EDUCATION

S.No.

DEGREE

UNIVERSITY/

BOARD

YEAR

PERCENTAGE

1.

M.Pharm

Industrial Pharmacy (equ. to Pharmaceutics)

S.G.S.I.T.S., Indore Rajiv Gandhi Proudyogiki Vishwavidyalaya.

Bhopal, India

APR 2001

73.90 (First class)

2.

B.Pharm

The Tamilnadu Dr.M.G.R. Medical University. Chennai

Tamil Nadu, India

Mar 1998

69.81 (First class)

3.

12th

SBSE, Tamil Nadu

Mar 1994

83.08 (First class)

4.

10th

CBSE, Tamil Nadu

Mar 1992

75.2 (Distinction with first class)

ACADEMIC ACHIEVEMENTS

Qualified in GRADUATE APTITUDE TEST IN ENGINEERING (GATE)-1999 with a percentile score of 91.75 (All India Rank 203)

Got distinction in first year of B.Pharmacy

Oral Presentation

An Oral Presentation on “Controlled Release of Verapamil Hydrochloride and Optimization through Central Composite Design” was given on the 54th Indian Pharmaceutical Congress 2002, held at Pune.

OTHERS

Participated in Antibiotic Awareness Day held on Nov 2018 at Security forces Hospital, Holy Makkah.

Certificate of Attendance on Basic Sterile Product Preparation held on OCT 2018

at King Abdullah Medical city, Holy Makkah

Certificate of Attendance on Emergency Medicine Tidbits, Toxicology held on OCT 2018

at King Abdullah Medical city, Holy Makkah

Certificate of Attendance on 1st MAKKAH GLAUCOMA SYMPOSIUM held on SEP 2018

at King Abdullah Medical city, Holy Makkah

Attended the 6th Annual Symposium on Recent Developments in Transfusion Medicine on FEB 2015, Makkah accredited by Saudi Commission for Health Specialties

Attended the Symposium of Common Diseases in Hajj on SEP 2015, Makkah, Saudi Arabia.

Participated in the Quality Circle program at STAR.

One of the members in the editorial section of the in-house magazine “Excelling Together” at STAR.

SEMINAR ATTENDED

Participated as an active volunteer in the International Symposium of Molecular Medicine organized jointly by The Buffalo State University, New York, Sun Pharma Advanced Research Centre and M.S. University of Baroda.

Participated in the Workshop INDUSTRY – ACADEMIA INTERACTION at the

51st Indian Pharmaceutical Congress, Indore.

Participated in the 51st Indian Pharmaceutical Congress (IPC), Indore 1999 as an active volunteer.

PERSONAL DETAILS

NAME : S.H.SEYED MOHAMED BUHARY

DATE OF BIRTH : 1st SEP. 1976.

FATHER’S NAME : Mr. M.Sheik Hydroose B.E.

LANGUAGES KNOWN : English, Tamil, Hindi and Arabic

MARITAL STATUS : Married

NATIONALITY : Indian

SEX : Male

QUALIFICATION : M.Pharm

AREA OF SPECIALIZATION : Industrial Pharmacy (equivalent to Pharmaceutics)

REFERENCES

1.Dr. N. Venkateshan M.Pharm., Ph.D

Principal

Arulmigu Kalasalingam College of Pharmacy

Krishnankoil – 626126

Srivilliputhur (Via), Tamilnadu

Phone no.-:045**-******(O), +919********* (Mobile)

*******@*****.***, ******@*****.***

2. Dr.Bhupinder Singh Bhoop,

Professor in Pharmaceutics and Biopharmaceutics,

Dean, Faculty of Pharmaceutical Sciences

University Institute of Pharmaceutical Sciences.

Panjab University, Chandigarh. India

Phone no 91-172-******* (O), +919********* (Mobile)

*******@**.**.**, *******@*****.***, *******@*****.***

3. Dr. T.R. Saini

Professor in Pharmaceutics,

Department of Pharmacy,

S.G.S.I.T.S. Indore – 452003, India

+919*********(Mobile), ******@******.**.**

4. Dr. R.S. Gaud

(Previously HOD – Dept. of Pharmaceutics, SGSITS, Indore)

Dean, Pharmaceutical Sciences,

Shobhaben Pratapbhai Patel School of Pharmacy & Technology,

Narsee Monjee Institute of Management Studies,

V. L. Mehta Road,Vile Parle (W), Mumbai – 400 056. India

Phone no. +91 – 22 – 42332000. ******@*****.***

Summary of my dissertation work of M.Pharm. III Sem. Project

Formulation of Extended Release Tablet Dosage forms of Verapamil Hydrochloride: Drug Release Optimization using Central Composite Design (CCD).

Compressed hydrophilic matrices constitute one of the most popular approaches for designing oral sustained release dosage forms. These possess distinct advantages of reproducibility in release profile, avoidance of dose dumping and straight forward manufacturing process. Release characteristics of compressed matrices have frequently been optimized using CCD to embark upon the preeminent formulation, thus saving a great deal of time, money and professional expertise.

A CCD for 2 factors, taking HPMC K4M and Sodium CMC (low viscosity), was adopted for optimization with factor levels suitably coded. Preliminary studies were conducted to investigate 3 levels of release retarding polymers. Nine randomized tablet batches for each combination were prepared by dry granulation. Amounts of microcrystalline cellulose and lubricants were kept constant, while diluents was used in quantity sufficient to maintain constant tablet weight. Tablets from each batch were monitored for the physical performance, drug content and dissolution, and data processed using ZOREL software. Diffusional release exponent (n) and MDT were determined, the type of release predicted and the values of t50%, t60%, t70% and t80% computed by Steinman interpolation. Response variables were n, t60%, MDT and the amount released in 12h (rel12h). Polynomial equations were obtained by Davies method using FACTOP software and 3D and contour response surfaces were drawn. Finally, optimum formulations were chosen as checkpoints by feasibility and grid searches, tablets formulated accordingly, evaluated for release performance and compared with predicted responses.

The HPMC-CMC combination was found to be useful in drug release regulation till 12h. Values of MDT and t60% augment, while rel12h values decrease with increasing concentrations of HPMC in almost linear fashion. However, “n” values diminished in a nonlinear manner with HPMC.

For CMC fraction, a milder linear trend with plateau results, suggesting negligible influence of low viscosity polymer at higher concentration. High degree of prognosis was discerned indicating successful use of CCD in formulating optimized matrices

PRESENTATION

54th Indian Pharmaceutical Congress (IPC), Pune, India, “Controlled Release of Verapamil Hydrochloride and Optimization through Central Composite Design”

talk.

DECLARATION

I hereby declare that the information’s furnished above are true to the best of my knowledge.

S.H. Seyed Mohamed Buhary

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