Matthew Paul May

**** ******* ****** ***, **

Albuquerque, NM 87114

505-***-**** Mobile

ac88uy@r.postjobfree.com (preferred)

BACKGROUND SUMMARY

Scientist and manager with over 25 years of experience applying Analytical Chemistry in commercial and research organizations. Broad science knowledge in pharmacology, chemistry, & instrumentation. Practical expertise in laboratory research, data collection and analysis, project management and safety compliance in a variety of settings. Strong teaching background, conference presentations, professional publications and grant proposals. An accomplished bench scientist and lab manager, able to collaboratively work and communicate with others to produce successful results and meet tight deadlines within budget.

LABORATORY SKILLS

LC-MS: Thermo Quantum and AB Sciex 5500/5000, 3000, 4000 triple quadrupole, Agilent 1100 single-quad, and Thermo Advantage ion trap instruments.

UPLC/HPLC: Agilent, Waters, Hitachi, Shimadzu, Thermo.

GC: Agilent 6890 w/FID.

ICP-MS: Thermo X Series II ICPMS with laser ablation.

ICP-OES: Perkin-Elmer Plasma 40.

Atomic Absorption: Perkin-Elmer, Instrumentation Labs, and Varian flame and graphite furnace systems.

NMR: Varian 300MHz system.

Strong Command of FDA and EMA Bioanalytical Guidance. Also skilled in cell culture and bioassay techniques, UV/Vis and IR Spectroscopy, solid Phase Extraction techniques and experienced in cGMP/cGLP regulations.

EDUCATION SUMMARY

Master of Science Degree in Analytical Chemistry, University of California, Davis, 23 March 2000. 3.84 GPA. Thesis: “Optical and Triplet-State Magnetic Resonance Studies of the Fullerene C60 and its Oxides C60O, C60O2, and C120O in Methylcyclohexane and Toluene.”

Bachelor of Science Degree in Chemistry, University of California, Davis, 20 June 1987. 2.90 GPA

Tomtec “TOMTEC Quadra4 User’s Training Course”, March 2015

AB Sciex “5500 User’s Training Course”, March 20-22, 2012.

ThermoFisher “X Series ICP-MS Training Course”, December 1-4, 2008.

Thermo-Finnigan “Mass Spectrometry for Drug Metabolism Training Course”, October 2003

Agilent “1100 LC/MS User’s Training Course”, November 2000.

EMPLOYMENT HISTORY

Research Associate, Lovelace Respiratory Research Institute, Albuquerque, NM. Developed, validated, and applied complex bioanalytical GLP methods for sample analyses supporting GLP and GMP pharmaceutical studies using HPLC and LCMS-MS for numerous small-molecule analytes. Authored Bioanalytical reports and SOP’s for associated validations and sample studies which I worked on. (10NOV14 – 01AUG18)

Scientist V, ALS Environmental, Kelso, WA. Developed, installed, validated and applied sample analysis LC-MS methods for various small-molecule analytes including EPA 1694, 539, 8321 and non-EPA methods for acrylamide, phthalates, PFC’s, and other analytes of environmental concern. Improved EPA 1694 method by adding new isotopes and optimizing signal processing by the MS. Developed several proprietary methods for LC-MS and was the “go-to” persons for LC method development. (27OCT10 – 21JUL14)

Research Chemist, Idaho State University, Pocatello, ID. Managed two campus research facilities: Bioanalysis Research Facility and later the Center for Archeology, Materials, and Applied Spectroscopy. Maintained laboratory supplies, and instruments, designed and implemented a Chemical Hygiene Plan, collaborated in analyses, grant proposals, and publication preparation. Projects included bioassay-guided fractionation of plant extracts and identification of purified compounds, metabolite, stability, pharmacokinetic, structure determination, and pharmaceutical quantitation studies using LC-MS-MS, HPLC, and other techniques (see publication list). Served as Chemical Safety Officer for the College of Pharmacy for four years, represented the College of Pharmacy on the University Safety Committee for three years. Served on the Provost's Select Safety Steering Committee to develop recommendations for an integrated safety policy. (25MAR02-21MAY10)

Chemist, Sunsweet Growers, Inc., Yuba City, CA (Contract Position). Collected and tested water samples from fruit wash bins for pH, conductivity, temperature, and brix using portable instruments. Correlated results with data from GC and HPLC analysis to show association of water quality as a function of fruit loading. JUL01-SEP01)

Senior Associate Chemist, Dade Behring Microscan, West Sacramento, CA. Developed new Microbiologic Identification and Antibiotic Susceptibility Testing kits. The work involved QC method development for the ID and AST subassemblies using HPLC and LC-MS. Prepared and presented results and periodic progress reports at team and company meetings. Created parameters for drying and storage of ID consumables, identified a dye to improve the ID reader function. (27MAR00 to 08JUN01)

Analytical Methods Development Chemist, Aerojet Fine Chemicals, Rancho Cordova, CA (contract). Developed analytical methods and supported research with minimal supervision for pharmaceutical syntheses in a cGMP environment using GC, HPLC, NMR. Prepared and presented research reports. Developed and validated of a method for detection by GC/FID of ethylene glycol in a pharmaceutical. Developed and applied an HPLC-UV method for cysteine which was used to show a supplier was selling low quality material to Aerojet. Demonstrated that a supplier tried to deceive Aerojet with poor quality material that company had intended to sell to Aerojet by developing an HPLC/UV method comparing cysteine samples from different sources. (03MAY99 to 29OCT99)

Teaching/Research Assistant, University of California, Davis. Directed undergraduate student laboratories, lead discussion groups, and graded student work. Investigated excited state spectroscopy of fullerenes. Maintained instrumentation, reported progress to my research advisor, and presented results at professional conferences. (SEP92 to DEC99)

Metals Group Leader, Coast to Coast Analytical Services, Benicia, CA. Analysis of solid and aqueous samples for heavy metals by graphite furnace AA, flame and hot & cold vapor AA using EPA, 17th ed. Standard Methods, and SW-846 methods. Developed methods and compiled data for DHS certification. Audited data, trained and supervised staff. Established a metals department. Trained one person to replace me when I resigned to attend graduate school. (AUG91 to SEP92)

Metals Coordinator, Caltest Analytical Laboratory, Napa, CA. Analyzed drinking/wastewater, soil, and sludge samples for inorganics with graphite furnace AA, ICP, FIAS, flame and hot & cold vapor AA by EPA and SW-846 methods. Developed methods, audited and approved data monitored and evaluated personnel and production. Supervised up to 5 people.

(APR89 to AUG91)

PUBLICATIONS

Li, A., May, M.P., Bigelow, J.C., “An LC/MS method for the quantitative determination of 7alpha-OH DHEA and 7beta-OH DHEA: an application for the study of the metabolism of DHEA in rat brain”, Biomedical Chromatography, 2010, 24(8), 833-837.

Li, A., May, M.P., Bigelow, J.C., “Identification of a Metabolite of Atrazine, N-ethyl-6-methoxy-N'- (1-methylethyl)-1,3,5-triazine-2, 4-diamine, Upon Incubation with Rat Liver Microsomes”, Journal of Chromatography B, 2006, 836 (2), 129-132.

Rhodes, R. S., Kuykendall, J. R., Heyneman, C. A., May, M. P., Bhushan, A., “Stability of Phenytoin Sodium Suspensions for the Treatment of Open Wounds”, International Journal of Pharmaceutical Compounding, 2006, 10 (1), 74-77.

Madaras-Kelly, K.; Michas, P., George, M.; May, M. P.; Adejare, A. “A Randomized Crossover Study Investigating the Influence of Ranitidine or Omeprazole on the Pharmacokinetics of Cephalexin Monohydrate”, Journal of Clinical Pharmacology, 2004, 44, 1391-1397.

May, M. P.; Costa, D. A.; Balch, A. L; Tinti, D. S. “Emission and Triplet-State ODMR Spectra of the Fullerene Oxides C60O, C60O2, and C120O in Glassy Solvents at Low Temperatures.” Book of Abstracts, 213th ACS National Meeting, San Francisco, April 13-17 (1997).

SEMINARS PRESENTED

"The Future of Plant-Derived Natural Products in Drug Discovery", Idaho State University Department of Biomedical and Pharmaceutical Sciences Graduate Seminar, 8 January 2010.

"Infrared Multiphoton Dissociation of Duplex DNA/Drug Complexes in a Quadrupole Ion Trap", Idaho State University Department of Pharmaceutical Sciences Graduate Seminar, 9 March 2007.

"Trace Analysis of Neurosteroids by LC-MS", Idaho State University Department of Pharmaceutical Sciences Graduate Seminar, 21 April 2006.

"High Throughput Screening in New Drug Discovery", Idaho State University Department of Pharmaceutical Sciences Graduate Seminar, 6 May 2005.

“Emission and Triplet-State ODMR Spectra of the Fullerene Oxides C60O, C60O2, and C120O in Glassy Solvents at Low Temperatures”, 213th ACS National Meeting, San Francisco, 16 April 1997.

"Fluorescence and Phosphorescence Studies of the Fullerenes C60, C60O, C60O2, and C120O at Low Temperatures", UC Davis Chemistry Department Graduate Seminar, 31 January 1997.

POSTERS PRESENTED

Ujwal S. Patil, Matthew P. May, and James C. Bigelow; “In vitro Screening for Anticancer Activity of an Ethnomedicinal Plant Obtained from Guatemala”, Intermountain Graduate Research Symposium, Utah State University, Logan, UT, 31 March 2010

Matthew P. May, Ujwal S. Patil, James C. Bigelow; “Cytotoxic Activity of Ethanolic Extracts of Several Ethnomedicinal Plants from the Rainforests of Peru.” 2010 Idaho Academy of Sciences Symposium, Twin Falls Idaho, 11-13 March 2010.

Ujwal S. Patil, Matthew P. May, James C. Bigelow; “Cytotoxic Activity of Blood Vine; An Ethnomedicinal Plant From The Rainforest of Guatemala.” 2010 Idaho Academy of Sciences Symposium, Twin Falls Idaho, 11-13 March 2010.

PUBLICATIONS

Bigelow, J. C.; Deaton, B.; Heiner, S.; Eley, J.; May, M.P.; “Natural Products Research in Two Ecosystems: Caves and Peruvian Rainforests.” 7th Annual INBRE Research Conference, Moscow, ID., 28-30 July 2008.

Li, A., May, M.P., Bigelow, J.C.; “Identification of a Metabolite of Atrazine, N-ethyl-6-methoxy-N'- (1-methylethyl)-1,3,5-triazine-2, 4-diamine, Upon Incubation with Rat Liver Microsomes”, American Society for Mass Spectrometry Annual Meeting, Seattle, 29 May - 2 June 2006.

May, M. P.; Costa, D. A.; Balch, A. L; Tinti, D. S.; “Emission and Triplet-State ODMR Spectra of the Fullerene Oxides C60O, C60O2, and C120O in Glassy Solvents at Low Temperatures.” 213th ACS National Meeting, San Francisco, 13-17 April 1997.

REFERENCES

Edward O'Connor, Senior Consultant, AegisBioConsult, LLC, 860-***-****, ac88uy@r.postjobfree.com

Ryan Sheeler, former Supervisor Small Molecule Bioanalysis Group at Lovelace Respiratory Research Institute, 203-***-****, ac88uy@r.postjobfree.com

Dr. Ewan Sinclair, Senior Research Associate, Turo University, Vallejo, CA. 707-***-****, ac88uy@r.postjobfree.com

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