GOLROKH MALIHI, PharmD, MPH, PhD

Address: *** **** *** **., *******, MO, 63011

Cell phone: 314-***-****

Email: ac7mu5@r.postjobfree.com

Education:

Ph.D. in Pharmacology, School of Pharmacy, Tehran University of Medical Sciences

Dissertation: “Effect of tricyclic and second generation antidepressant drugs on adenosine

receptors and ouabain-induced arrhythmia in guinea-pig atria”

M.S. in Public Health (MPH), Institute of Public Health, Tehran University of Medical Sciences

Thesis: “Effect of Diet and Nutrition on Prevention and management of Cancer”

Doctor of Pharmacy, School of Pharmacy, Tehran University of Medical Sciences

Thesis work: “Serum Concentration of Complement in Different Stages of cancer Chemotherapy in Patients with Leukemia”

Employment history:

Washington University School of Medicine, St Louis, MO 2017- 2018

Department of Psychiatry

Research scientist under the supervision of Dr. Glaser

Washington University School of Medicine, St. Louis, MO 2003-2016

Department of Biochemistry and Molecular Biophysics

Visiting scientist in the laboratory of Dr. Elliot L. Elson

Fargol Research Group, St. Louis, MO 1998-present

Associate director of R&D for household cleaning agents and detergents

Gateway Clinic, 7491 Big Bend BLVD, St. Louis, MO, 63119. 2016-2017

clinical trial and research scientist

Barnes Jewish Hospital, St. Louis, MO 2009-2016

Fulltime employee of the Center for Diversity and Cultural Competence

Shahid Beheshti School of Medicine, Tehran, Iran 1990-2014

Department of Pharmacology

Lecturer and research instructor (teacher) of animal experiments in-vivo and- invitro to the medical and pharmacy students from 1990-2014

Assistant Professor of Pharmacology, 1996-2014

Lecturer Schools of Medicine, Dentistry and Nursing, 1990-1996

Awards and honors

Presentation award, 14th Congress of Pharmacology, April, 1998, Tehran, Iran. Title: “On the mechanism of positive inotropic effect of fluoxetine on the isolated guinea-pig atria.”

Presentation award, 3rd Congress of Clinical Psychiatry and Psychology, December, 1994, Tehran, Iran. Title: “A comparative double blind study on the efficacy and cardiovascular side effects of maprotiline and amitriptyline in major depressed patients.”

Professional affiliations

Member: American Heart Association; Diversity RX, USA; AWIS, USA; Society of Physiology and Pharmacology, Iran; Iranian Medical Association; Iranian Pharmaceutical Association

Additional training:

“Sigma Life Science Gene Silencing and Knockdown Quantitation Technologies Workshop,” Sigma-Aldrich, St. Louis, MO, November, 2007.

“Workshop on Cellular Electrophysiology and Patch Clamp/Current Clamp Techniques,” Shahid Beheshti University of Medical Sciences, Tehran, Iran, January, 2002.

“Workshop on Biostatistics,” Shahid Beheshti University, Tehran, Iran, annually from 1988-2003.

Various workshops on cell culture, behavioral and cardiovascular pharmacology, biostatistics and grant writing, since 1996.

Research skills and experience:

In vivo studies:

Induction of diabetes in rats through administration of Alloxan or Streptozocin.

Acute and chronic drug administration in mice, rats, and guinea pigs.

Induction of IV and general anesthesia in animal models.

Induction of withdrawal syndrome after opioid deprivation and prevention of this phenomenon via methadone.

In vitro studies:

Cell culture techniques

Tissue engineering techniques

Immunostaining and fluorescence microscopy

Isolated atria in vitro techniques.

Preparation and experiments involving animal studies

Clinical studies:

A randomized comparative study to reduce weight in diabetic and overweight patients consuming one third diet plus exercise and meditation. Malihi G, Khan M, Khattak H., Mar. 2018

Malihi, G (PI). “A comparative double-blind study on the efficacy and cardiovascular side effects of maprotiline and amitriptyline in major depressed patients,” Shahid Beheshti University of medical Sciences.1999.

Publications

Book:

1.Malihi, G. “Drug Therapy of Inflammation.” Tehran: Shahid Beheshti University Press, 1988.

Journal and conference papers:

Malihi G, Amanatkar, H, Glaser P. Impact of psychotropic medications on electrical activity of induced pluripotent stem cell-derived cardiomyocytes, presented in a seminar in Washington University, School of Medicine, July, 2018

Malihi G, Elson E L, a review on qualifications and cost-effectiveness of iPSC-derived cardiomyoctes in drug screening tests. International Journal of pharmaceutical research. Inpress.

Malihi G, Elson EL, Nikoui V, Biomechanical/biochemical factors contributing to cardiac fibrosis in the heart and engineered cardiac tissue. Iranian Journal of Pharmaceutical research. (2018), 10 (1), 51-59.

Malihi G, Khan M, Khattak H. A randomized comparative study to reduce weight in diabetic and overweight patients consuming one third diet plus exercise and meditation. In Press.

Alizadeh A M, Khori V, Zahedi M, Jand Y, Yazdi H R, Azadbakht, Malihi G, Shakiba D,

Malihi G, Nikouei V, Bakhtiarian A, Pousti A, Cardiovascular benefits of nigella Sativa extract: its main compound thymoquinone inhibits ouabain-induced arrhythmia in isolated rat atria. International Journal of Pharmacological Research (2017). WWW. IJPRONLINE

Malihi G, Nikouie V, Bakhtiarian A, Pousti A, Elson EL, Thymoquinone inhibits arrhythmia in isolated rat atria. ATVB PVD Scientific sessions, May 5-7, 2016, Nashville, TN.

Malihi G, Effect of thymoquinone on the proliferation and α- smooth muscle production of chick embryo cardiac myofibroblasts. Presented in the 17th Iranian Congress of Physiology and Pharmacology 2009.

Pousti A, Malihi G, Effect of paroxetine on ouabain-induced arrhythmia in isolated guinea-pig atria. Poster presentation in EPHAR, July 28, 2008, Manchester, UK.

Pousti A, Zare Jahromi, A, Malihi G, Ojaghzadeh H, Effect of sodium valproate on ouabain-induced arrhythmia in isolated guinea-pig atria. Iranian Journal of Pharmacology and experimental Therapeutics 6:41-43, 2007.

Malihi G, Bakhtiarian A, Effect of nano-molar concentrations of lysophosphatidic acid on the calcification and proliferation of mouse vascular smooth muscle cells. Conference on Nanotechnology, San Francisco, 2008.

Malihi G, Elliot EL. Effect of adenosine on the proliferation and differentiation of the 3- dimensional reconstituted tissue constructs of chick embryo fibroblasts. Iranian Journal of Pharmacology and Therapeutics, 2006; 5(2), 157.

Pousti A., Deemyad T, Malihi G, Brumand K, Involvement of adenosine in the effect of fluoxetine on isolated guinea-pig atria. Pharmacol. Res. 2006; 53(1), 44-8

Pousti A, Deemyad T, Malihi G. Mechanism of inhibitory effect of citalopramon isolated guinea-pig atria in relation to adenosine receptor. Human Psychopharmacol. 2004; 19(15): 347-50.

Pousti A., Malihi G., Naghibi B., “The effect of citalopram on ouabain induced arrhythmia of isolated atria,” Human Psychopharmacology, 2003; 18:121-124

Pousti A. Malihi G., Abdollahi M., Rahravan E., “Effect of fluoxetine on ouabain induced arrhythmia of isolated guinea pig atria,” Indian Journal of Pharmacology, 2003; 35:55-58.

Ostad S. N., Farhad-Khani M., Minaiee B., Malihi G., Abdollahi, M., “The blood pressure and dermal sensitivity effects of nylon hallow fiber releasing glycerin trinitrate in-vivo,” Daru, Vol 10, No 3, 2002.

Pousti A, Malihi, G, Naghibi B “The effect of citalopram on ouabain–induced arrhythmia of guinea pig isolated atria,” Hum Psychopharmacol. 2003 Mar;18(2):121-4

Pousti A., Malihi G., Bakhtiarian A., “The comparative effects of 4 antihistamine drugs on rat isolated atria,” Iranian Journal of Pharmacology and Therapeutics, 1 (2), Nov. 2002.

Malihi G., “NSAIDs induced gastropathy prevention and Treatment strategies,” Razi Pharmaceutical Journal, 6 (138), 55 – 64, 2001.

Prof. Vahid Khori, Ph.D.

Golestan University of Medical Sciences

Golestan Cardiovascular Research Center

Faculty of Medicine

Gorgan, Iran

Pousti A. Malihi G, Abdollahi M,Toosi ER*, “The effect of fluoxetine on oabain-induced Arrhythmia in isolated guinea-pig atria. Indian Journal of Pharmacology 2003; 35: 55-58

References:

1)Prof. Elliot Elson, Ph.D.

Washington University School of Medicine

Department of Biochemistry and Molecular Biophysics

314-***-****, 314-***-**** (cell)

ac7mu5@r.postjobfree.com

Prof. Mariana Beltcheva, PhD. Director of hCTO, Center for Regenerative Medicine, Washington University in St. Louis, School of Medicine, Email: ac7mu5@r.postjobfree.com.

C/O Dr. Angella Bowman, Campus box 8103, 660 S Euclid Ave, St. Louis, MO, 63110-1093

2)Dr. Hamid Reza Amanatkar MD, Psychiatristspecialty in Child Psychiatry

Washington University Dept. of Psychiatry, Cell Phone: 314-***-****

Email: ac7mu5@r.postjobfree.com

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