Sign in

Medical Clinical Research

Scarborough, ON, Canada
October 31, 2018

Contact this candidate


Gencheng Hargen Zhang, MD, Ph.D.

Toronto, Canada +1-647-***-****

Cardiovascular Surgeon and Clinical Researcher

Driven professional with 30 years of international achievement, and specialization in the treatment of cardiovascular disease, respiratory disease, and cardiothoracic disease. More than a decade of experience conducting clinical studies on patients with Hypoplastic left heart syndrome(HLHS) to analytically compare effectiveness Norwood and Hybrid surgical procedures. Successfully developed a method to measure patients’ system vascular resistance, pulmonary circulation resistance, and cardiac index. Skill for compiling data from different sources and performing data analysis using SAS and SPSS statistics software. Experience leading the design and development of research programs and protocols. Authored and published more than 30 papers.


Cardiovascular Disease/Surgery

Clinical Research Studies

Experiment Study.

Knowledge ofGood Manufacturing Practices (cGMP), Food & Drug Administration (FDA) and Health Canada and global regulatory practice.

Clinical Data management Collection/Analysis

Chart Review/summary

Post-Surgery Treatment

Electrical Medical History Record System

Multi-disciplinary team player

Statistical Analysis

Strategic Planning

Knowledge of IATA regulations and laboratory procedures

experience in cellular immunology, stem cell biology, cellular therapies.

Technology: Windows 10, Microsoft Office (Word, Excel, Access, PowerPoint) SAS, SPSS Statistics Software,


Church Wellness Center, Toronto, Canada 2017 – Present


Foster and maintain strong professional relationships with internal and external partners.

Delegate assignments and oversee staff performance to ensure tasks are completed properly.

Facilitate professional development opportunities, through training and staff meetings.

Manage capital budgets, review expenses, and implement functional and strategic plans.

Hospital for Sick Children of Toronto University of Toronto, Canada 2002 – 2017

Clinical Data Manager, Clinical Research Associate, Cardiac Surgery, CCU, Cath Lab

Studied hemodynamics following repair of complex heart disease and cardiopulmonary bypass.

Studied influence of postoperative systemic oxygen transport on neurologic and functional outcomes

in patients undergoing heart surgery, and provided data for guidance of post-surgery treatment.

Studied pathophysiological change of patients who underwent Norwood and Hybrid surgery, comparing

effects on patients with hypoplastic left heart syndrome and single ventricle circulation.

Monitored hemodynamic of patients who underwent radiofrequency ablation and balloon valvotomy.

Studied effects of bi-ventricle pacing on cardiac function and hemodynamics after open-heart surgery.

Studied the effects of NO, sildenafil, flolan on patients who had serious pulmonary hypertension.

Key Results

Conducted a clinical study over 10 years on patients with HLHS, performing data analysis on two

surgical procedures (Norwood and Hybrid), with the conclusion that the Hybrid is the best procedure.

Developed and measured patient’s system vascular resistance, pulmonary circulation resistance, and cardiac index.

Designed and measured patient’s energy expenditure and evaluate the patient's nutrition status.

Fuwai Heart Hospital, Beijing, China 1997 – 2002

Cardiac Surgeon

Hospital performed about 20,000 open-heart surgeries with mortality below 1% and 50,000 PTCA per year.

Evaluated and diagnosed patients, performed successful surgeries, and provided treatment after surgery.

Conducted clinical research and an experimental study to complete thesis for Ph.D. in Cardiovascular Disease.

Primary Operator for the Following Surgeries

Coronary Artery Bypass Graft (CABG), surgical repair of atrial septal defect (ASD), ventricular septal

defect (VSD), and atrioventricular septal defect (AVSD), mitral valvuloplasty and replacement, and

surgical repair of double outlet right ventricle (DORV), Tetralogy of Fallot (TOF), and pulmonary Atresia (PA).

First Assistant for the Following Interventions

Surgical repair of aortic aneurysms, aorta-pulmonary septal defect, aorta incompetence, Ebstein anomaly, transposition of the great arteries (TGA), Marfan’s Syndrome, Anomalous pulmonary venous connection,

Fontan operation, total cavopulmonary anastomosis, Maze operation, Mustard operation, Ross operation.

Clinical Fellow, Cardiovascular Surgery

Hospital of Fourth Military Medical University

Surgical Residency Doctor

North General Hospital in China


Ph.D. of Medicine, Cardiovascular Disease (Surgery)

Chinese Academy of Medical Sciences, Peking Union Medical College

Master of Medicine, Cardiovascular Disease (Surgery)

Fourth Military Medical University, Xi’an, China

Bachelor of Medicine (MD)

Third Military Medical University, Chongqing, China


Organ Procurement Specialist Clinical Training, 2013

Toronto General Hospital, University of Toronto

Intensive Medical Literacy Course, 2010

Toronto General Hospital, University of Toronto

SAS Statistics Course Training, 2005

Hospital for Sick Children of Toronto, University of Toronto

Contact this candidate