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Molecular Assay Development

Location:
Oakland, California, United States
Salary:
80000
Posted:
August 27, 2018

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Resume:

TYLER WILLIAMS GOLDMAN

*** ********* **** #*** 510-***-****

Oakland CA, 94618 ac6t09@r.postjobfree.com

SKILLS

Execution of Laboratory Techniques (DNA extraction, RNA extraction and quantification, PCR, NGS, etc.)

Experience with design control.

Understanding of Statistical Models used in large scale genotyping and molecular studies.

Experience with Programs such as Excel, Microsoft Access, proficient in JMP statistical modeling.

Training lab personnel in protocols and procedures.

Experience with working in cross-functional teams.

Knowledge of California regulatory and CFR policies for laboratory settings, hazardous waste creation.

Experience in experimental design and execution.

Effective communication abilities.

Excellent written and verbal skills.

PROFESSIONAL EXPERIENCE

DxTerity Diagnostics, LOS ANGELES CA July 2014 – Present

Scientist August 2017 – Present

Promoted to scientist role due to reliable design of characterization studies, validation studies, assay expertise, and clear and well-written reports.

Plan, conduct and manage experimental designs for early development characterization studies of DxTerity assays, specifically RNA expression profile assays for radiation exposure and auto immune disease states such as lupus and multiple sclerosis.

Responsible for higher level FMEA and validation study planning, execution, and record writing in preparation for FDA submission.

Responsible for root cause investigation, assay technical support, and troubleshooting of both new and defined failure modes of assays.

Lead daily meetings with staff to discuss project schedule and budget.

Prepare presentations and reports to relay the status and findings of ongoing experiments to the product development group in weekly meetings.

Responsible for on-boarding new employees in lab techniques.

Act as team lead for off-site training to personnel of other labs participating in DxTerity studies.

Senior Research Associate July 2016 – August 2017

Conducted research and prepared technical analyses on projects involving DxTerity assay technology.

Responsible for writing work instructions and SOPs for DxTerity’s on-site procedures and protocols.

Helped design the quality control testing system for DxTerity reagents.

Designed and executed characterization and validation studies of DxTerity technology.

Assisted in early design, manufacturing, and functional characterization efforts of DxTerity’s MicroCollection Device.

Oversaw day to day use of lab space and lab equipment by the product development team.

Worked in small collaborative team settings to achieve desired results, actively re-prioritizing goals based on data from the previous day’s work.

Designed and delivered off-site training in DxTerity’s REDI-Dx assay to personnel at collaborating labs.

Responsible for new employee onboarding and training.

Chemical Hygiene Officer October 2014 – Present

Lead lab clean up and re-organization, disposing of large amounts of hazardous chemicals stored on site that were no longer necessary for daily tasks.

Responsible for updating chemical inventory with newly received chemicals and the accompanying SDS documentation.

Responsible for responding appropriately in the case of an on-site chemical spill.

Approve orders of hazardous chemicals and advise on proper use and precautions when handling them on-site.

Member of the safety committee, who meets quarterly to discuss potential safety issues and propose improvements to DxTerity’s systems.

Research Associate July 2014 – June 2016

Executed planned studies in the laboratory.

Responsible for processing sample data, and presenting project updates at weekly product development meetings.

Team Leader, University of California, Los Angeles April 2012 - December 2012

Team leader for 6-month research project focused on increasing the knowledge of the scientific field regarding Mycobacteriophage. The lab is centered on the isolation of a single bacteriophage specific for Mycobacteria Smegmatis from a local soil sample. The lab used M. Smeg as the host bacteria due to its ease of growth in the lab and its close relationship to the pathogen Mycobacterium Tuberculosis. After enrichment and isolation via a series of serial dilution plates, a high titer lysate was created and used for both electron microscopy (for further phenotypic analysis) as well as viral DNA extraction. After receiving the full genome of our phage, we assembled a full contig and linearized the phage genome to the standard assembly of Mycobacteriophage genomes on phagesDB. Manually annotated all genes present to add to the overall evolutionary database of bacteriophage, as well as to look for functional genes that could lead to wet lab experiments looking at the efficacy of bacteriophage therapy. http://www.hhmi.org/grants/professors/hatfull.html

Volunteer Lab Assistant, Laboratory of Dr. Robert Schiestl, UCLA 2014 – June 2014

Helped oversee and run project protocols written by PI

Responsible for cell culturing, DNA extraction, Gel Electrophoresis, PCR DNA amplification, and other benchwork

Scientific Advisor and Consultant, Carolyn Katzin MS, CNS, UCLA November 2013 - June 2014

Provide insight and consultation related to field of study (Immunology and Molecular Genetics) for scientific presentations

Review for content and revise slides for scientific presentations regarding the Human Gut Microbiome and Nutritional Immunology

UCLA Catering October 2011 -June 2014

Promoted to a training and supervisory role for new student employees

Ensure events are properly assembled

Lead catering teams

Set up, serve, and break down large events

Food Service, Ackerman Plaza, UCLA September 2009 - November 2010

Various customer service and logistics positions with campus food service providers including Wetzel’s Pretzels, Relaxation, Greenhouse and RX

Boys and Girls Club of America, Oakland, California April 2008 - August 2008

Volunteer. Assisted neighborhood inner-city children aged 8-15 with homework and other school activities. Responsible for ensuring safe and engaging play among the children while at the facility.

EDUCATION

University of California, Los Angeles December 2012

B.S.Microbiology, Immunology, and Molecular Genetics



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