Assistant C
Resume:
Juan Carlos Pena-Philippides, B.S., M.S
***** ****** ****, *****, ** 33626
**************@*****.***
Nationality: US
A. A cademics and Honors :
● Master In Water Resources: Hydrology and Water Quality and Public Health, 2017, University of New Mexico, Albuquerque, NM
● Bachelors of Science Graduation: Summa Cum Laude in Biology with a minor in Chemistry, 2003, University of New Mexico, Albuquerque, NM
● University of New Mexico Department of Neurosurgery Staff Awards. Albuquerque, NM December 2014
● Caballero Scout del Peru con palmas de Oro, equivalent to Eagle Scout, 1987 B. T hesis :
● Middle Rio Grande Surface and Well Water Quality and The Health Implications to Humans Health: Giardiasis and Cryptosporidiosis Master Thesis: University of New Mexico, Department of Water Resources, Graduation July 2017.
MS Advisors Dr. Floyd Frost, Dr, Kristine Tollestrup, Dr. Bruce M Thomson, and Dr. Mark Stone.
● The chronic effects of nicotine primarily affect the Th-1 but not the Th-2. Undergraduate Honors Thesis: University of New Mexico, Department of Biology, Graduation 2003.
Bsc. Thesis Advisors: Dr. Larry L. Barton, PhD University of New Mexico and Dr. Mohan Sopori, PhD LRRI.
C. Positions and Employment:
● 2016-2017 Research Scientist, Department of Neurosurgery School of Medicine, University of New Mexico, Albuquerque, NM
● 2012-2016 Research Specialist, Department of Neurosurgery School of Medicine, University of New Mexico, Albuquerque, NM
● 2011-2012 Acting Project Manager, Lovelace Counter Act research Center for Pulmonary Fibrosis, Lovelace Respiratory Research Institute, Albuquerque, NM
● 2006 – 2012 Senior Research Technologist, Respiratory Immunology and Asthma Program, Lovelace Respiratory Research Institute, Albuquerque, NM
● 2009-2009 Clinical Microbiologist, TRICORE Laboratories Albuquerque, NM
● 2003 - 2006 Research Technologist, Respiratory Immunology and Asthma Program, Lovelace Respiratory Research Institute, Albuquerque, NM
● 2000 - 2003 Laboratory Assistant, Respiratory Immunology and Asthma Program, Lovelace Respiratory Research Institute, Albuquerque, NM D. L ABORATORY and Practical Skills
● Environmental Microbiology
● Clinical Microbiology
● Analytical Methods of Water Testing
● Genomics, extraction and purification of DNA & RNA
● Genotyping
● Luminex Assay
● Immunohistochemistry
● Basic Flow Cytometry
● qPCR.
● Reverse Transcriptase PCR.
● Culture of Human, Animal, Bacterial, and Yeast cells.
● Methods for analytical and organic chemistry.
● Transfection.
● Purification of Plasmids (Mini Preps).
● Radio Immuno Proliferation Assay.
● Radio Immuno Assay.
● Electrophoresis: SDS-PAGE y Agarose Gel.
● Protein analysis by Western Blot, ELISA
● Quantification of Protein: Bradford, Micro Bradford and Lowry
● Microscopy: Confocal and Fluorescence
● Handling of Laboratory Animals: Mice and Rats.
● Sterile Techniques to use and handle Cell cultures and Microbiology.
● Surgical Techniques for implantation of mini Osmotic for self-delivering pumps in rats and mice and implantation to brain Cannulas to direct brain delivery in rats.
● Neurosurgery procedures in mice and rats.
● Necropsy: extraction of organs to further isolate primary cell culture DNA, RNA and Proteins.
● Statistical Analysis: Minitab, Excel, Prism, and basic Mat lab
● Software Office.
● Small animal care including: Mice, Rats.
● Medium animal care including: cats, dogs, small farm animals, small non-human primates
● Large animal care including: Gorillas, Chimpanzees, Orangutans, Horses.
● Small and large animal surgery assistant
● Sterilization and castration of small animals
● Anesthesia for small and medium size animals
● Assist Veterinarians to any surgery
● Aseptic techniques for curing surgical wounds
● Aseptic techniques for surgical procedures
● Knowledge on medication and dose calculations.
● Performed physical exam to small and medium sized animals
● Techniques to study Apoptosis.
● Manufacturing kits for Research.
E. PERSONAL and PROFESIONAL APTITUDES:
● Leadership.
● Project Management.
● Initiative.
● Capacity of Organization.
● Excellent aptitude in written and verbal presentations.
● Instinct to recognize opportunities.
● Capacity to work under pressure.
● Excellent interpersonal ability.
● Excellent team work aptitude.
● Knowledge of three languages
● Business Aptitude
● Extensive internationals experience
● Advance computers: MS Office, Fox, Internet, websites, etc.
● Excellent capacity of communication in three languages.
● Self-Lerner
● Experience in Business Administration
● Strategic
● Problem Solving
● Innovator and Communicator
● Oriented to take Action.
F. Selected peer-reviewed publications (in chronological order). 1. Pena-Philippides, J. C.: The chronic effects of nicotine primarily affects the Th-1 but not the Th-2. Honors Thesis University of New Mexico, Department of Biology, Graduation 2003.
2. Kalra, R., S. P. Singh, J. C. Pena-Philippides, R. J. Langley, S. Razani-Boroujerdi and M. L. Sopori: Immunosuppressive and anti-inflammatory effects of nicotine administered by patch in an animal model. Clin. Diagn. Lab. Immunol. 11(3): 563-568, 2004. 3. Langley, R. J., R. Kalra, N. C. Mishra, F. F. Hahn, S. Razani-Boroujerdi, S. P. Singh, J. M. Benson, J. C. Pena-Philippides, E. B. Barr and M. L. Sopori: A biphase response to silica. I. Immunostimulation is restricted to the early stage of silicosis in Lewis rats. Am. J. Respir. Cell Mol. Biol. 30: 823-829, 2004.
4. Razani-Boroujerdi, S. P. Singh, C. Knall, F. F. Hahn, J. C. Pena-Philippides, R. Kalra, R. J. Langley and M. Sopori: Chronic nicotine inhibits inflammation and promotes influenza infection. Cell. Immunol. 230(1): 1-9, 2004.
5. Singh, S. P., S. Razani-Boroujerdi, J. C. Pena-Philippides, R. J. Langley, N. C. Mishra and M. L. Sopori: Early postnatal exposure to cigarette smoke impairs the antigen-specific T-cell responses in the spleen. Toxicol. Lett. 167(3): 231-237, 2006. 6. Pena-Philippides, J. C., S. Razani-Boroujerdi, S. P. Singh, R. J. Langley, N. C. Mishra, R. F. Henderson and M. L. Sopori: Long- and short-term changes in the neuroimmune-endocrine parameters following inhalation exposures of F344 rats to low-dose sarin. Toxicol. Sci. 97(1): 181-188, 2007. 7. Razani-Boroujerdi, S., R. T. Boyd, M. I. Davila-Garcia, J. S. Nandi, N. C. Mishra, S. P. Singh, J. C. Philippides, R. Langley and M. L. Sopori: T cells express 7-nicotinic acetylcholine receptor subunits that require a functional TCR and leukocyte-specific tyrosine kinase for nicotine-induced Ca2+ response. J. Immunol. 179(5): 2889-2898, 2007. 8. Mishra, N. C., J. Rir-Sima-ah, R. J. Langley, S. P. Singh, J. C. Peña-Philippides, T. Koga, S. Razani-Boroujerdi, J. Hutt, M. Campen, K. C. Kim, Y. Tesfaigzi and M. L. Sopori: Nicotine primarily suppresses lung Th2 but not goblet cell and muscle cell responses to allergens. J. Immunol. 180(11): 7655-7663, 2008.
9. Razani-Boroujerdi, S., M. Behl, F. F. Hahn, J. C. Pena-Philippides, J. Hutt and M. L. Sopori: Role of muscarinic receptors in the regulation of immune and inflammatory responses. J. Neuroimmunol. 194(1-2): 83-88, 2008.
10. Zhuang, J., F. Xu, M. J. Campen, C. Zhang, J. C. Pena-Philippides and M. L. Sopori: Inhalation of the nerve gas sarin impairs ventilatory responses to hypercapnia and hypoxia in rats. Toxicol. Appl. Pharmacol. 232(3): 440-447, 2008. 11. Langley RJ, Mishra NC, Pena-Philippides JC, Hutt JA, Sopori ML: Granuloma formation Induced by low dose chronic silica inhalation is associated with an anti-apoptotic response in Lewis rats. JToxicol Environ Health A. 2010; 73(10): 669-83 12. Razani-Boroujerdi S, Langley RJ, Singh SP, Pena-Philippides JC, Gundavarapu S, Mishra NC, Sopori ML: The Role of IL-1β in Nicotine-induced immunosuppression and Neuroimmune Communication. J. Neuroimmune Pharmacol, 2011 Dec:6(4):585-96 13. Langley Rj, Mishra NC, Peña-Philippides JC, Rice BJ, Seagrave JC, Singh SP, Sopori ML: Fibrogenic and redox-related but not proinflammatory genes are upregulated in Lewis rat model of chronic silicosis. JToxicol Environ Health A. 2011:74(19):1261-79 14. Singh SP, Gundavarapu S, Peña-Philippides JC, Rir-Sima-ah J, Mishra NC, Wilder JA, Langley RJ, Smith KR, Sopori ML. Prenatal secondhand cigarette smoke promotes Th2 polarization and impairs goblet cells differentiation and airway mucus formation. J Immunol. 2011 Nov 1:187(9):4542-52.
15. Mishra NC, Rir-Sima-ah J, Grotendorst GR, Langley RJ, Singh SP, Gundavarapu S, Weber WM, Peña-Philippides JC, Duncan MR, Sopori ML. Inhalation of sulfur mustard causes long-term T cell-dependent inflammation: Possible role of Th17 cells in chronic lung pathology. Int Immunopharmacol. 2012 May:13(1):101-8 16. Gundavarapu S, Wilder JA, Mishra NC, Rir-Sima-Ah J, Langley RJ, Singh SP, Saeed AI, Jaramillo RJ, Gott KM, Pena-Philippides JC, Harrod KS, McIntosh JM, Buch S, Sopori ML. Role of nicotinic receptors and acethylcholine in mucus cell metaplasia, hyperplasia, and airway mucus formation in vitro and vivo. J. Allergy Clin Immunology, 2012, May9. 17. Juan Carlos Pena-Philippides, Yirong Yang, Olga Bragina, Sean Hagberg, Edwin Nemoto, and tamara Roitbak. Effects of Pulsed Electromagnetic Field (PEMF) on Infarct Size and Inflamation after Cerebral Ischemia in Mice. Transl S troke Research 2 014 A ug; 5(4):491-500
18. Caballero-Garrido E, Pena-Philippides JC, Lordkipanidze T, Bragin D, Yang Y, Erhardt EB, Roitbak T. J Neurosci. 2015 Sep 9; 35(36):12446-64. In Vivo Inhibition of miR-155 Promotes Recovery after Experimental Mouse Stroke. G. A bstracts and Presentations:
1. Razani-Boroujerdi, S., R. Kalra, S. P. Singh, R. J. Langley, J. C. Pena-Philippides, C. A. Conn and M. L. Sopori: IL-1b regulates the neuroimmune effects of nicotine. Society of Neuroscience Abstracts, No. 28, Orlando, FL, 2002. 2. Razani-Boroujerdi, S., R. Kalra, C. Knall, F. F. Hahn, S. P. Singh, J. C. Pena-Philippides, R. J. Langley and M. L. Sopori: Inhibitory effects of nicotine on inflammation and leukocyte migration. SOT, Salt Lake City, UT, 2003. 3. Razani-Boroujerdi, S., R. Kalra, C. Knall, F. F. Hahn, S. P. Singh, J. C. Pena-Philippides, R. J. Langley and M. L. Sopori: Chronic nicotine inhibits the migration of leukocytes to the site of inflammation. The 6th World Congress on Inflammation, Vancouver, Canada, August 2003.
3. Campen, M. J., S. Razani-Boroujerdi, S. Lucas, J. C. Pena-Philippides and M. Sopori: Differential effects of sarin gas exposure regimen on airway reactivity and cytokine expression. Society American Toxicology Society 45th Annual Meeting, San Diego, CA, May 2006.
4. Mishra, N. C., R. J. Langley, S. R. Boroujerdi, J. C. Pena-Philippides, J. S. Nandi and M. L. Sopori: Nicotine suppresses allergic inflammation and mast cell degranulation. American Toxicology Society 45th Annual Meeting, San Diego, CA, May 2006. 5. Pena-Philippides, J. C., S. Razani, F. Xu, S. Singh, N. Mishra, R. Langley, R. Kalra and M. Sopori: Sarin-induced neuroimmune modulation and lung injury. U.S. Army Department of Bio-Defense Meeting, San Juan de Puerto Rico, May 2006. 6. Razani-Boroujerdi, S., J. C. Pena-Philippides, M. J. Campen, S. Lucas and M. L. Sopori: Manifestations of acute and chronic lung injury in response to sarin inhalation. Society of Toxicology 45th Annual Meeting, San Diego, CA, May 2006. 7. Langley, R. J., N. C. Mishra, J. C. Pena-Philippides, S. Razani-Boroujerdi and M. L. Sopori: Differences in the apoptotic response in acute and chronic silicosis. Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007. 8. Mishra, N. C., R. J. Langley, S. Razani-Boroujerdi, J. C. Pena-Philippides and M. L. Sopori: Nicotine inhibits leukotriene production induced by IgE receptor stimulation. American Thoracic Society: International Meeting, San Francisco, CA, May 2007.
9. Razani-Boroujerdi, S., T. R. Boyd, M. I. Davila-Garcia, J. S. Nandi, N. Mishra, S. P. Singh, J. C. Pena-Philippides, R. Langley and M. L. Sopori: Characterization of 7-nChR in T cells. American Thoracic Society International Meeting, San Francisco, CA, May 2007.
H. LANGUAGES:
● Spanish Advance ( Written, and verbal)
● English Advance ( Written, and verbal)
● German Intermediate ( Written, and verbal)
● Greek Basic ( Written, and verbal)
I. P ERSONAL REFERENCES:
1. Dr. Shannon Bruse, PhD
Senior Manager, Translational Genetics
Regeneron Genetics Center
777 Old Saw Mill River Road
Tarrytown, NY
Cell #: 914-***-****
Desk #: 914-***-****
*******.*****@*********.***
2. Dr. Mohan Sopori, PhD
Senior Scientist, LRRI
2425 Ridgecrest Dr. SE
Albuquerque, NM USA
m ******@****.***
3. Mr. Daniel Juri, MS.
Senior Research Technologist, LRRI
2425 Ridgecrest Dr. SE
Albuquerque, NM USA
*****@****.***
4. Mr. Timothy Murrell, MCRP
Senior Water Planner, Denver, CO.
Denver, CO USA
***.*******@*****.***
5. Dr. William A. Palmisano, PhD
Deputy Director of Microbiology,
Office of the technical Director
Dugway Proving Ground
Tedt-Dp-Td, MS#6
Bld. 4531, B Street
Dugway, UT 84022
435-***-**** office
*******.*********@**.****.***
6. Dr.Yohannes Tesfaigzi, PhD
Scientist, COPD program, LRRI
2425 Ridgecrest Dr. SE
Albuquerque, NM USA
y *******@****.***
7. Dr. Jorge Romero, PhD
Investigador adjunto / CIQUIBIC
Departamento de Quimica Biologica,
Facultad de Ciencias Quimicas,
Universidad Nacional de Cordoba,
Cordoba, Argentina
*******@****.***.***.***.**
8. Dr. Larry L Barton, PhD
Professor Emmeritus,
Department of Biology
University of New Mexico
l ******@***.***
9. Mr. Jules Rir Si mah, MS, MT
Molecular Technologist
Tricore Laboratories,
Albuquerque, NM
s ********@*****.***
10. Dr. Matthew J Campen, PhD, MSPH
Associate Professor
Department of Pharmaceutical Science
University of New Mexico
School of Pharmacy
m ******@*****.***.***
11. Dr. Richard M. Plunkett, PhD
Assistant Professor
Department of Biology
University of British Columbia
r ******.********@***.**
12. Dr. Tamara Roitbak, PhD
Assistant Professor,
Dept. of Neurosurgery
UNiversity of New Mexico
Office 505-272- 0558
********@*****.***.***
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