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Location:
Irvine, California, United States
Posted:
August 11, 2018

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EXPERTISE

Processes & Techniques: Protein Purification, Immunoaffinity Chromatography, Enzyme Purification/Assay/Kinetic, Gel Electrophoresis, Bioanalytical & Purification Yield Analysis, Oxidation Assay, Analytical Assay, Clinical Trail Instrumentation & Technologies: PAGE, ELISA, Spectrophotometer (Vis/UV), Spectrofluorometer, Western Blot, Purification Systems WORK EXPERIENCES

University of California, Irvine (UCI), USA.

Dr. Vaziri Laboratory, Division of Nephrology and Hypertension, Medical Science C- 362, School of Medicine, UCI, Irvine, CA.

1. Assistant Specialist II (Mar 15, 2017 – Present) 2. Assistance Specialist I (Mar 15, 2016 – Mar 15, 2017) As a Volunteer, Research Assistant:

● Research on the role of chronic kidney disease on the expression of inflammatory and oxidative stress proteins in rat skeletal muscle.

● The extraction of cytoplasmic and nuclear proteins from skeletal muscle cells using scientific methods.

● Isolation and measurement of expression level of inflammatory, necrosis, and oxidative stress proteins from skeletal muscle using PAGE and Western Blot techniques.

● The processing of skeletal muscle tissue for H & E and Masson's trichrome staining.

● Analysis of pathology images of skeletal muscle tissues.

● Performing complex data analysis using Graphpad Prism. Mohammad Ali Ghaffari

Biochemist Specializing

3900 Parkview Ln Apt # 16B, Irvine, California, 92612 ac6mxk@r.postjobfree.com & ac6mxk@r.postjobfree.com

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● Research for published articles on kidney disease and skeletal muscle.

● Writing an article titled, "Effect of Ferric citrate therapy on markers of oxidative stress, inflammation and fibrosis in skeletal muscle of animals with chronic kidney disease".

University of Jundishapour, Ahvaz, Iran.

Biochemistry Department, Medical School, Jundishapour University, Ahvaz, Iran. 1. Professor (Jan 1, 2014 – Present).

2. Associate Professor (Aug 12, 2006 – Jan 1, 2014). 3. Assistance Professor (Sep 3, 2002 – Aug 12, 2006). As a faculty member:

● Participation in the teaching of biochemistry, laboratory biochemistry, and clinical biochemistry (for students of Medical School, Dental School, and Pharmacy School).

● Participation in the teaching of hormone biochemistry, tissue biochemistry, enzymology, and clinical biochemistry (for M.Sc and Ph.D. students in biochemistry major).

● Design and perform of projects, including on diabetic, autism, breast cancer, and infertility.

● Supervisor of the thesis of M.Sc and Ph.D. students.

● Publish several articles in scientific journals. OTHER EXPERIENCE & PROFESSIONAL MEMBERSHIPS

1. Head of Biochemistry Department

● Medical School, Jundishapour University, Ahvaz, Iran.

● Start date and end: Jan 3, 2013 – Mar 1, 2016.

2. Member, Iranian Biochemistry Association (2002 – 2016) 3. Member, Molecular and Cellular Center, Jundishapour University, Ahvaz, Iran (2005 – 2016)

EDUCATIONS

1. Clinical Research

● Division of Continuing Education, University of California, Irvine, USA.

● Start and graduation date: Apr 1, 2018 – Mar, 2019. 2. Ph.D. in Clinical Biochemistry (GPA: 4)

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● School of Pharmacy, Isfahan University of Medical Sciences and Health Services, Isfahan, Iran.

● Start and graduation date: Feb 2,1996 – Aug 3, 2002.

● Thesis title: The inter-relationship between indium and iron metabolism, in vitro and in vivo experiments.

3. M.Sc. in Clinical Biochemistry (GPA: 4)

● School of medicine, Tehran University of Medical Sciences and Health Services, Tehran, Iran.

● Start and graduation date: Sep 7,1992 – Feb 2, 1995.

● Thesis title: Extraction of gap junction proteins from normal human liver and the study of its interaction with some regulatory agents; Calmodulin, cAMP and calcium ion and the sites of interactions.

4. B.Sc. in Biology (GPA: 4)

● Faculty of Basic Scinces, Tarbit Moalem University, Tehran, Iran.

● Start and graduation date: Feb 3,1986 – Aug 3, 1990. HONOR/AWARD

1. Outstanding Young University Award (2002)

Isfahan University of Medical Sciences, Iran

2. Excellence in Teaching (2004, 2005, and 2008)

Jundishapour University of Medical Sciences, Ahvaz, Iran RESEARCH INTERESTS

Diabetes, proteomics and structural biology, LDL changes (oxidation, glycation, and carbamylation), Enzymology, Toxicology

PUBLICATIONS

Articles

1. Moshtaghie AA and Ghaffari MA. Identification of amino acids involve in indium binding to serum human apo-transferrin. Iran Biomed J. 2001; 5: 149-153. http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-1- 388&slc_lang=fa&sid=1&sw=Transferrin

2. Moshtaghie AA and Ghaffari MA. Study of the binding of iron and indium to human serum apo- transferring. Iran Biomed J. 2003; 7: 73-77. http://ibj.pasteur.ac.ir/browse.php?a_id=541&sid=1&slc_lang=fa Page 4 of 11

3. Ghaffari MA and Moshtaghi AA. The effect of indium on intestinal absorption of iron using everted gut sac method. Scenti J Hamedan Uni Med Sci Health. 2003; 10: 5-11. (In Farsi) http://en.journals.sid.ir/ViewPaper.aspx?ID=4414 4. Ghaffari MA and Moshtaghi AA. The study of indium distribution in rat liver, kidney and brain tissues. Koomesh. 2004; 5: 151-156. (In Farsi) http://koomeshjournal.semums.ac.ir/browse.php?a_id=180&sid=1&slc_lang=en 5. Ghaffari MA, Dabbagh MA and Gharib A. Human erythrocyte superoxide dismutase encapsulated in positively charged liposomes. Iran J pharm sci. 2005; 1: 153-160. http://ijps.ir/article_1863_448.html

6. Ghaffari MA, Kadkhodaei M, Saffari MR and Pedram M. Monitoring of serum nitric oxide in patients with acute leukemia. Iran J pharm Res. 2005; 4: 233-237. 7. Ghaffari MA and Ghiasvand T. Effect of lycopene on formation of low density lipoprotein-copper complex in copper catalyzed peroxidation of low density lipoprotein, as in vitro experiment. Iran Biomed J. 2006; 10: 191-196. http://ibj.pasteur.ac.ir/browse.php?a_id=253&slc_lang=en 8. Ghaffari MA, Saffari MR and Ghiasvand T. The effect of α-tocopherol on copper binding to low density lipoprotein. Iran J Pharma Res. 2006; 5: 209-214. 9. Ghaffari MA and Mojab S. In vitro effect of α-tocopherol, ascorbic acid and lycopene on low density lipoprotein glycation. Iran J Pharma Res. 2007; 6: 265-271. https://www.researchgate.net/publication/26626558_In_Vitro_Effect_of_a- Tocopherol_Ascorbic_Acid_and_Lycopene_on_Low_Density_Lipoprotein_Glycatio n

10. Ghaffari MA and Mojab S. Influnce of flavonols as in vitro on low density lipoprotein glycation. Iran Biomed J. 2007; 11: 185-191. http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-1-95&slc_lang=en&sid=1&sw= 11. Ghaffari MA and Ghiasvand T. In vitro effect of naringin and quercetin on LDL oxidation via their influence in copper binding to LDL. Iran J Dia Lip Dis. 2007; 7: 23-33. (In Farsi)

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=I- JJ7iEAAAAJ&cstart=60&citation_for_view=I-JJ7iEAAAAJ:Se3iqnhoufwC 12. Ghaffari MA, Aberomand M and Motlagh B. In vitro inhibition of human sperm creatine kinase by nicotine, cotenin and cadmium, as a mechanism in smoker men infertility. Intr J Fertil Steril. 2008; 2: 125-130. 13. Ghaffari MA, Aberomand M and Motlagh B. Evaluation of optimum in vitro for creatine kinase enzyme kinetic study of isolated from human sperm. Med J Ahwaz Jundishapur University Med Sci. 2009; 8: 323-330. (In Farsi) http://journals.ajums.ac.ir/components4.php?rQV=8BkMApDZJV2ZhV3ZuFGbfZG fABDQ6QnchR3cfZGfARTMApDZJRnblJXYw9lZ8BkMyEDQ6QWStVGdp9lZ8 BEOApDZJxWY0J3bQxWYuJXdvp2XmxHQyATNApDZJ52bpR3Yh9lZ 14. Ghaffari MA and Mojab S. Glucose influences on copper ion-dependent oxidation of low density lipoprotein. Iran Biomed J. 2009; 13: 59-64. https://www.ncbi.nlm.nih.gov/pubmed/19252679

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15. Hosseini F, Gharib Naseri MK, Badavi M, Ghaffari MA, Shahbazian H and Rashidi I. Protective effect of beta carotene pretreatment on renal ischemia/reperfusion injury in rat. Pakis J Biol Sci. 2009; 12: 1140-1145. http://scialert.net/fulltext/?doi=pjbs.2009.1140.1145 16. Ghaffari MA and Shanaki M. In vitro inhibition of low density lipoprotein carbamylation by vitamins, as an ameliorating atherosclerotic risk in uremic patients. Scan J Clin Lab Invest. 2010; 70: 122-127.

http://www.tandfonline.com/doi/abs/10.3109/00365511003624137?journalCode=icl b20

17. Ghaffari MA and Ghiasvand T. Kinetic study of low density lipoprotein oxidation by copper. India J Clin Biochem. 2010; 25: 29-36. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3453007/ 18. Hosseini F, Gharib Naseri MK, Badavi M, Ghaffari MA, Shahbazian H and Rashidi I. Effect of beta carotene on lipid peroxidation and antioxidant status following renal ischemia/reperfusion injury in rat. Scan J Clin Lab Invest. 2010; 70: 259-263. https://www.ncbi.nlm.nih.gov/pubmed/203*****-**. Ghaffari MA and Shanaki M. Evaluation of in vitro effect of flavonoids on human low density lipoprotein carbamylation. Iran J Pharma Res. 2010; 9: 67-74. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869556/ 20. Ghaffari MA and Ghiasvand T. Effects of alpha-tocopherol on the velocity of low density lipoprotein oxidation by cupric ions. Acta Medica Iranica. 2010; 48: 289-294. http://acta.tums.ac.ir/index.php/acta/article/view/4050 21. Ghaffari MA and Motlagh B. In vitro effect of lead, silver, tin, mercury, indium and bismuth on human sperm creatine kinase activity: a presumable mechanism for men infertility. Iran Biomed J. 2011; 15: 38-43.

https://www.ncbi.nlm.nih.gov/pubmed/21725498

22. Mansouri E, Panahi M, Ghaffari MA and Ghorbani A. Effect of grape seed proanthocyanidin extract on oxidative stress induced by diabetes in rat kidney. Iran Biomed J. 2011; 15: 100-106. https://www.ncbi.nlm.nih.gov/pubmed/219*****-**. Ghaffari MA and Ghiasvand T. The study of kinetic inhibition of copper (II)- induced oxidation of low-density lipoprotein by lycopene.J Food Biochem. 2011; 35: 228-240.

http://onlinelibrary.wiley.com/doi/10.1111/j.1745-4514.2010.00378.x/abstract 24. Azizi A, Ranjbari A, Ghaffari MA, Jahan F. Comparative evalution of lactate dehydrogenase (LDH) and Aspartate aminotransferase (AST) levels in periodontal diseases. J Isfahan Dental School. 2011; 7: 265-271. (In Farsi) http://jids.mui.ac.ir/index.php/jids/article/view/338/1610 25. Mansouri E, Panahi M, Ghaffari MA and Ghorbani A. Effect of grape seed proantihocyanidin extract on oxidative stress and antioxidant enzymes in kidney of rat with diabetic nephropathy. Romanian J Biophys. 2011; 21: 243-252. http://www.rjb.ro/abstract.php?id_art=320

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26. Kajbaf F, Ghaffari MA and Kajbaf MJ. Reduced serum homocysteine levels in diabetic patients. Iran J Patholo. 2012; 7: 14-18. http://ijp.iranpath.org/article_8398.html

27. Mansouri E, Panahi M, Ghaffari MA and Ghorbani A. Grape seed proanthocyanidin extract ameliorates albuminuria and renal sclerosis in experimental diabetic nephropathy rats. Asian Biomed. 2012; 6: 195-202. https://www.degruyter.com/view/j/abm.2012.6.issue-2/1905-7415.0602.046/1905- 7415.0602.046.xml

28. Mansouri E, Panahi M, Ghaffari MA and Ghorbani A. Grape seed proanthocyanidin extract ameliorates diabetic nephropathy in rats. Sci Res Essays. 2012; 7: 2263-2269.

http://www.academicjournals.org/article/article1380791462_Mansouri%20et%20al.p df

29. Ghaffari MA and Rostami M. Lipid peroxidation and nitric oxide levels in male smokers’ spermatozoa and their relation with sperm motility. J Reprod Infertil. 2012; 13: 81-87. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719338/ 30. Ghaffari MA and Rostami M. The effect of cigarette smoking on human sperm creatine kinase activity: As an ATP buffering system in sperm. Inter J Fertil Steril. 2013; 6: 258-265. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850315/ 31. Ghaffari MA, Zeinali M, Barzegar Asadabadi E, Jamalan M, Jahandideh S. Affinity enhancement of HER2-binding Z (HER2:342) affibody via rational design approach: a molecular dynamics study. J Biomol Stru Dyn. 2014; 32: 1919-1928. http://www.tandfonline.com/doi/abs/10.1080/07391102.2013.842499 32. Mohammadzadeh G and Ghaffari MA. Additional effect of diabetes mellitus type 2 on the risk of coronary artery disease: Role of serum adiponectin. Iran Red Cres Med J. 2014; 16: e8742.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964435/ 33. Mohammadzadeh G, Ghaffari MA, Bafandeh A and Hosseini SM. Association of serum soluble leptin receptor and leptin levels with breast cancer. J Res Med Sci. 2014; 19: 433-438. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116575/ 34. Mohammadzadeh G, Ghaffari MA, Bafandeh A and Hosseini SM. Effeect of leptin receptor Q223R polymorphism on breast cancer risk. Iran J Basic Med Sci. 2014; 17: 588-594.

https://pdfs.semanticscholar.org/7d2c/6058e61270ab3175256de77eb7642ab08ff7.pdf 35. Raffie E, Salemi Z, Ghaffari MA and Goodarzi MT. The effect of metformin, acarbose and their combination on visfatin level in nicotinamide/streptozotocin- induced type 2diabetic rats. J Shahed Uni. 2014; 22: 53-62. (In Farsi) http://en.journals.sid.ir/ViewPaper.aspx?ID=443500 36. Ghaffari MA, Sede SA, Rashtchizadeh N, Mohammadzadeh G and Majidi S. Association of CRP gene polymorphism with CRP levels and coronary artery disease in type 2 diabetes in Ahvaz, Southwest of Iran. Bioimpacts. 2014; 4: 133-139. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204038/ 37. Ahmad B, Nikzamir A, Ghafari M, Mohamadzadeh G, Latifi M, Bafandeh A, Fathi M, Yekaninejad MS and Nikzamir M. Lack of association between Page 7 of 11

cyclooxygenase 22765G/C gene polymorphism and breast cancer risk in Ahvaz, west-south Iran. Mol Biol Rep. 2014; 41: 997–1001. https://link.springer.com/article/10.1007/s11033-013-2944-1 38. Mohammadzadeh G, Ghaffari MA, Bafandeh A, Hosseini SM and Ahmadi B. The relationship between 2548G/A leptin gene polymorphism and risk of breast cancer and serum leptin levels in Ahvazian women. Iran J Cancer Prev. 2015; 8: 100- 108. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411471/ 39. Afrisham R, Aberomand M, Ghaffari MA, Siahpoosh A and Jamalan M. Inhibitory effect of Heracleum Persicum and Ziziphus Jujuba on activity of alpha- amylase. J Botany. 2015; 2015: Article ID 824683, 8 Pages. https://www.hindawi.com/journals/jb/2015/824683/

40. Ghaffari MA, Mansouri MT, Haghighyzadeh MH and Rafie E. Evalution of serum vaspin and chemerin levels in type 2 diabetic and treated with anti diabetic drugs metformin and acarbose in rats. J Fasa Uni Med Sci. 2015; 5: 120-133. (In Farsi)https://journal.fums.ac.ir/browse.php?a_id=680&slc_lang=en&sid=1&printcas e=1&hbnr=1&hmb=1

41. Ghaffari MA, Raifie E, Slemi Z, Goodarzi MT and Ghasemi M. Comparing serum visfatin levels in restricted diet, type 2 diabetic, and insulin resistant rats and those in normal rats: The relation of serum visfatin levels with serum glucose level and lipid profile. J Fasa Uni Med Sci. 2015; 5: 435-443. (In Farsi) http://journal.fums.ac.ir/browse.php?a_id=659&sid=1&slc_lang=en 42. Faam B, Ghaffari MA, Ghairi A, Azizi F. Epigenetic modifications in human thyroid cancer (Review). Biomed Reports. 2015; 3: 3-8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251143/ 43. Rashtchizadeh N, Sede SA, Ghaffari MA, Mohammadzadeh G and Majidi S. Associations of pentraxin 3 with presence and severity of coronary artery disease in type 2 diabetes patients. Turk J Biochem. 2015; 40: 37-43. http://www.turkjbiochem.com/2015/037-043.pdf

44. Jamalan M, Rezazadeh M, Zeinali M and Ghaffari MA. The effect of ascorbic acid and alpha tocopherol supplementations on serum leptin, tumor necrosis factor alpha, and serum amyloid A levels in individuals with type 2 diabetes mellitus. Avicenna J Phytomed. 2015; 5: 531-539.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678498/ 45. Mohammadzadeh G, Karimpour F, Ghaffar MA, Kheirollah AR, Saki A. Association of Cholesteryl Ester Transfer Protein-TaqIB Polymorphism with Coronary Artery Disease in Patients with Type 2 Diabetes. Med Lab J. 2015; 9: 53- 59. https://goums.ac.ir/mljgoums/article-1-807-fa.pdf 46. Jamalan M, Zeinali M, Ghaffari MA. A molecular dynamics investigation on the inhibition mechanism of cholesteryl ester transfer protein by anacetrapib. Medici Chemi Res. 2016; 25: 62-69. https://link.springer.com/article/10.1007%2Fs00044- 015-1471-0

47. Ghaffari MA, Payami SA, Payami SP, Ashtary-Larky D, Nikzamir A, Mohammadzadeh G. Evalution of insulin resistance indices in type 2 diabetic Page 8 of 11

patients treated with different anti-diabetic drugs. Open J Endocr Metab Disea. 2016; 6: 95-101. http://file.scirp.org/pdf/OJEMD_2016021614372253.pdf 48. Salemi Z, Rafie E, Goodarzi MT, Ghaffffffffari MA. Effect of metformin, acarbose, and their combination on the serum visfatin level in nicotinamide/sterptozocin- induced type 2 diabetic rats. Iran Red Crescent Med J. 2016; 18: e23814. doi: 10.5812/ircmj.23814.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884299/ 49. Sadegh-Nejadi S, Aberomand M, Ghaffari MA, Mohammadzadeh G, Siahpoosh A, Afrisham R. Inhibitory Effect of Ziziphus Jujuba and Heracleum Persicum on the Activity of Partial Purified Rat Intestinal Alpha-Glucosidase Enzyme. J Mazandaran Univ Med Sci. 2016; 26: 135-146. (In Farsi) http://jmums.mazums.ac.ir/article-1-7234-en.html

50. Mohammadzadeh G, Ghaffari MA, Bazyar M, Kheirollah A. Association between two common polymorphism (single nucleotide polymorphism-250G/A and - 514C/T) of the hepatic lipase gene and coronary artery disease in type 2 diabetic patients. Adv Biomed Res. 2016; 5: 27.

https://www.ncbi.nlm.nih.gov/pubmed/27014654

51. Karimpour F, Mohammadzadeh G, Kheirollah A, Ghaffari MA, Saki A. Association of I405V polymorphism of colesteryl ester transfer protein gene with coronary artery disease in men with type 2 diabetes. ARYA Atheroscler 2016; 12: 69-75. https://www.ncbi.nlm.nih.gov/pubmed/274*****-**. Ghaffari MA, Aberumand M, Roshanmehr H, Hosseini SH. Reduction of High Glucose-Induced Nitric Oxide Synthase Expression in Human Vascular Endothelial Cells by Ascorbic Acid and α-Tocopherol. Inter J Pharm Res Allied Sci, 2016; 5: 135-143. http://ijpras.com/vol5-iss2/IJPRAS-201*-*-*-***-***.pdf 53. Montazeri S, Ghafari MA, Haghighi MH, Teimoory Bakhsh S. Investigating Relationship between Saliva Estriol to Progesterone Ratio and Preterm Delivery. Inter J Pharm Res Allied Sci, 2016: 5: 264-269. http://ijpras.com/vol5-iss3/IJPRAS- 201*-*-*-***-***.pdf

54. Jamalan M, Ghaffari MA, Hoseinzadeh P, Hashemitabar M, Zeinali M. Human Sperm Quality and Metal Toxicants: Protective Effects of some Flavonoids on Male Reproductive Function. Intr J Fertil Steril. 2016; 10: 215-222. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948074/ 55. Ashtary-Larky D, Ghaffari MA, Noorbehbahani M, Alipour M. Association of Smoking with Semen Quality and -Calpain Level in Normospermia: A Case- Control Study. J Family Repro Health. 2016; 10: 15-20. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930449/ 56. Mousavinejad E, Ghaffari MA, Afsharmanesh MR, Ashtary-Larky D, Kooti W, Afrisham R. Mitochondrial dysfunction in autistic children and oral coenzyme Q10 supplementation treatment (Review). Autism Open Access. 2016; 6 :4. DOI: 10.4172/2165-7890.1000189.

https://www.omicsgroup.org/peer-reviewed/mitochondrial-dysfunction-in-autistic- children-and-oral-coenzyme-q10supplementation-treatment-78947.html Page 9 of 11

57. Aminzadeh Z, Jamalan M, Chupani L, Lenjannezhadian H, Ghaffari MA, Aberomand M, Zeinali M. In vitro reprotoxicity of carboxyl-functionalised single- and multi-walled carbon nanotubes on human spermatozoa. Andrologia 2016; e12741. DOI: 10.1111/and.12741.

http://onlinelibrary.wiley.com/doi/10.1111/and.12741/abstract 58. Ghaffari MA, Mousavinejad E, Riahi F, Mousavinejad M, Afsharmanesh MR. Increased serum levels of tumor necrosis factor-alpha, resistin, and visfatin in the children with autism spectrum disorders: A case-control study. Neur Res Inter 2016; Article ID 9060751, 7 pages.

https://www.hindawi.com/journals/nri/2016/9060751/ 59. Jamalan M, Ghaffari MA, Zeinali M, Moradi-Beiranvand M. A mechanism- based study on inhibitory effect of nicotine and cotinine on human lactate dehydrogenase C. Arvand J Health Med Sci. 2016; 1: 87-89. http://arvandj.abadanums.ac.ir/article_43218_0.html 60. Keshtzar E, Khodayar MJ, Javadipour M, Ghaffari MA, Bolduc DL, Rezaei M. Ellagic acid protects against arsenic toxicity in isolated rat mitochondria possibly through the maintaining of complex II. Hum Exp Toxicol. 2016; 35: 1060-1072. https://www.ncbi.nlm.nih.gov/pubmed/26628001

61. Ghaffari MA, Mohammadzadeh G, Rezazadeh M, Rashidi H. Effects of Vitamins C and E on Serum Resistin, Hs-CRP, Lipid Profile and Insulin Levels in Patients with Type 2 Diabetes. Med Lab J. 2016; 10: 6-12. http://goums.ac.ir/mljgoums/browse.php?a_id=857&sid=1&slc_lang=en 62. Sharifat N, Mohammadzadeh G, Ghaffari MA, Dayati P, Kamato D,. Little PJ, Babaahmadi-Rezaei H. Endothelin-1 (ET-1) stimulates carboxy terminal Smad2 phosphorylation in vascular endothelial cells by a mechanism dependent on ET receptors and de novo protein synthesis. J Pharm Pharma, 2017; 66-72. DOI: 10.1111/jphp.12654. http://onlinelibrary.wiley.com/doi/10.1111/jphp.12654/epdf 63. Karimi M, Babaahmadi-Rezaei H, Mohammadzadeh G, Ghaffari MA. Effect of Silibinin on Maspin and ERα Gene Expression in MCF-7 Human Breast Cancer Cell Line. Iran J Patholo. 2017; 12: 50-59. http://ijp.iranpath.org/article_24871.html 64. Ghanemi M, Pourshohod A, Ghaffari MA, Kheirollah A, Amin M, Zeinali M, Jamalan M. Specific targeting of HER2-positive head and neck squamous cell carcinoma line HN5 by Idarubicin-ZHER2 affibody conjugate. Curr Cancer Drug Targets. 2017 Apr 26. doi: 10.2174/1568009617666170427105417. https://www.ncbi.nlm.nih.gov/pubmed/28460618

65. Dayer D, Tabar MH2, Moghimipour E, Tabandeh MR, Ghadiri AA, Bakhshi EA, Orazizadeh M, Ghaffari MA. Sonic hedgehog pathway suppression and reactivation accelerates differentiation of rat adipose-derived mesenchymal stromal cells toward insulin-producing cells. Cytotherapy. 2017;19: 937-946. doi: 10.1016/j.jcyt.2017. 05.003. Epub 2017 Jun 21. https://www.ncbi.nlm.nih.gov/pubmed/286*****-**. Afrakhteh M, Zeinali M, Ghaffari MA, Pourshohod A, Jamalan M. Investigating the Combination therapy effect of Trastuzumab and Idarubicin on Growth Inhibition Page 10 of 11

of HER2-Positive Breast Cancer Cells Line (SK-BR-3). J Fasa Uni Med Sci. 2017; 7: 353-360. (In Farsi) https://journal.fums.ac.ir/article-1-1270-en.html 67. Karimi M, Babaahmadi-Rezaei H, Mohammadzadeh G, Ghaffari MA. Effect of Silibinin on Maspin and ERα gene expression in MCF-7 human breast cancer cell line. Iran J Pathol. 2017; 12: 135-143.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831069/pdf/ijp-12-135.pdf 68. Mousavinejad E, Ghaffari MA, Riahi F, Hajmohammadi M, Tiznobeyk Z, Mousavinejad M. Coenzyme Q10 supplementation reduces oxidative stress and decreases antioxidant enzyme activity in children with autism spectrum disorders. Psychiatry Res. 2018; 265: 62–69.

https://www.sciencedirect.com/science/article/pii/S0165178117317869 My Published Works are also in the following address: https://www.ncbi.nlm.nih.gov/pubmed/?term=Ghaffari+MA Book

●Ghaffari MA. Biochemical pathways of organic compounds.Ayat, Ahwaz, Iran, 2005; 1st Ed. (In Farsi)

PRESENTATIONS

*Listing only includes international congresses

1. Ghaffari MA. Identification of amino acid involve in indium binding to serum human apo-transferin. 10th International Congress of Toxicology, Tampere, Finland, July 11-15, 2004.

2. Ghaffari MA, Dabbagh MA and Gharib A. Purification of copper/zinc superoxide dismutase from human erythrocytes and entrapped in multilamellar liposomes. 30th FEBS Congress and 9th IUBMB Conference, Budapest, Hungary, July 2-7, 2005.

3. Ghaffari MA and Mojab S. In vitro study of glucose effect on susceptibility of LDL to oxidative modification in presence of copper ion. 1st International and 6th National Congress on Quality Improvement in Clinical Laboratories. Tehran, Iran, February 13-16, 2008.

4. Ghaffari MA and Mojab S. Glucose influence on copper ion dependent oxidation of native and glycated low density lipoprotein. 45th Congress of the European Societies of Toxicology. Rhodes, Greece, October 5-8, 2008. 5. Ghaffari Ma, Abroumand M and Motlagh B. In vitro effect of three compounds of cigarette smoking particle phase on human sperm creatine kinase activity. 46th Congress of the European Societies of Toxicology. Dresden, Germany, September 13-16, 2009.

6. Ghaffari MA and Ghiasvand T. copper kinetic effect on low density lipoprotein oxidation. 10th Iranian Congress of Biochemistry and 3rd International Page 11 of 11

Congress of Biochemistry and Molecular Biology. Tehran, Iran, November 16-19, 2009.

7. Ghaffari MA and Shanaki Bavarsad M. In vitro study of rutin, taxifolin and quercetin effect on low density lipoprotein carbamylation. 10th Iranian Congress of Biochemistry and 3rd International Congress of Biochemistry and Molecular Biology. Tehran, Iran, November 16-19, 2009.

8. Ghaffari MA and Motlagh B. In vitro toxic effect of lead on human sperm creatine kinase activity. The XII International congress of Toxicology. Barcelona, Spain, July 19-23, 2010.

9. Ghaffari MA and Shanaki M. Protective effects of catechin, morin, myricetin, kaempferol, luteolin and naringin on human LDL carbamylation in vitro. 12th Iranian congress of Biochemistry and 4th International Congress of Biochemistry and Molecular Biology. Mashhad, Iran, September 6-9, 2011. 10. Ghaffari MA and Shanaki M. Lycopene inhibits LDL carbamylation, a protective mechanism for atherosclerosis risk reduction. 9th International Congress on Coronary Artery Disease. Venice, Italy, October 23-26, 2011. REFERENCES

1. Nosratola D. Vaziri

ac6mxk@r.postjobfree.com

Medical Science C-362, Division of Nephrology & Hypertension, School of Medicine, University of California, Irvine, CA.

2. Ane C.F. Nunes

ac6mxk@r.postjobfree.com

Medical Science C-362, Division of Nephrology & Hypertension, School of Medicine, University of California, Irvine, CA.

3. Lau, Wei Ling,

ac6mxk@r.postjobfree.com

Medical Science C-362, Division of Nephrology & Hypertension, School of Medicine, University of California, Irvine, CA.



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