Jessica MacDonald

Southborough, MA *****

ac6h0v@r.postjobfree.com

802-***-****

Relevant Experience

Genzyme/Sanofi Framingham, MA March 2013-Present

Manufacturing Technician Sr., Full Time Position

•Upstream small and large scale mammalian tissue culture operations ensuring proper aseptic technique.

•Conform to all SOPs, current GMP, PPE requirements.

•Qualified trainer for all small and large-scale operations as well as single-use wave bag implementation.

•SOP writing and revision, Batch record review, +QDCI, DCM.

•Daily monitoring of cultures includes scale-ups, sampling and in process assays for 125mL up to 160L bioreactors, as well as the harvest and refeeding batch process. Product integrity is insured utilizing dynamic environmental monitoring in BCS/LFH.

•Aseptic filling of therapeutic drug during transversal cross-training with purification. Routinely take bioburden, mycoplasma, Bradford, LAL, and ELISA samples to be tested. Monitor aseptic media fills within the hood.

Genzyme/Sanofi Framingham, MA June 2012-March 2013

Quality Control Analyst I, Contract Position

•Trained all manufacturing groups to preform dynamic monitoring to ensure product integrity while sampling.

•Ensure sterility of manufacturing suites through Environmental Monitoring.

•Microbial plate counting, growth promotion, gram stain, manual bench tests, microscopy, pipetting, water collection and sampling.

•Conform to SOPs, cGMP guidelines and documentation practices. Good laboratory practices. Aseptic technique.

Cell Signaling Technology, Danvers, MA September 2011- December 2011

Laboratory Intern (full-time, semester long internship)

•Primary focus in siRNA development and production, assisted in the design and development of siRNA products, analysis of cell signaling pathways.

•Performed protein analysis and antibody validation utilizing techniques such as Western Blotting, SDS-PAGE, gel electrophoresis, ELISA.

•Cell culture, aseptic technique, inoculation, sonication, chemical dilutions, transfections, development and analysis of lysates and their specific antibody signaling pathways.

Endicott College, Beverly, MA January 2009-January 2011

Science Laboratory Assistant

•Directly assist the Science Laboratory Manager with daily institutional and administrative duties. Organize, catalog, and file records into databases associated with departmental research.

•Prepared equipment and materials for all college laboratory courses and individual research projects; including media preparation, growth promotion, chemical stock solutions, glass wash duties, etc.

Education

Endicott College Beverly, MA May 2012

Bachelor of Science, Biotechnology/Pre-Professional

GPA: 3.7/4.0 Cum Laude Biological Honor Society, Phi Sigma, 2010-2012

Bond University Queensland, Australia Study Abroad Exchange Program

GPA: High Distinction Bond Scholars Program December 2010

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