Katherine Groschwitz, Ph.D.

*** ******** ***

Cheltenham, PA 19012

ac4tju@r.postjobfree.com

513-***-****

PROFILE

Effective communicator skilled at translating and articulating complex material in a clear, accurate, and effective manner through both written and oral communication

Multifaceted scientist with medical and clinical training and research experience in academic, clinical, pharmaceutical industry, and international settings

Skilled writer utilizing creative and critical thinking, analytical reasoning, and effective literature research to develop and manage projects from conception through publication

Team player utilizing expertise and skills to support colleagues and clients and contribute to teams

WRITING AND EDITING EXPERIENCE

Apothecom, Yardley, PA, 04/2016-12/2017

Senior Medical Writer

Lead writer for MedEd, med affairs, and internal and external training projects for both US and global antifungal and HIV accounts, which encompassed HIV-associated comorbidities including, HCV, CV, renal, liver, bone, and CNS disease

Researched, interpreted, designed, and created branded and unbranded, annotated, medical, educational, and promotional communication tactics targeting healthcare professionals, MSLs, patients, and internal scientific teams

Publication planning, scientific platform, abstracts, and publication development for sickle cell disease

Interpreted and analyzed data, and researched and developed scientific content in the field of osteoarthritis

Client-facing role with direct collaboration, open communication, and on-site presentations with clients. Built, maintained, and lead relationships/communications with clients

Collaborated with and directed creative and digital teams to develop infographic-heavy presentations that go beyond just words on a slide

Researched PubMed and the internet; created and edited slide decks, speaker’s notes, concepts, brochures, training material, peer discussion guides, executive summaries, infographics, standard response letters; posters, and scripts for video-based presentations; created figures, graphs, and illustrations; worked on ad boards

Good management skills in moving projects forward, prioritizing work assignments, and strategic planning

Complete Publication Solutions/ICON, North Wales, PA, 08/2014-03/2016

Medical Writer

Publication planning: developed 20 abstracts, 20 posters, 7 slide presentations, and 18 manuscripts in the fields of immunology, dermatology, and rheumatology

Experience in managing multiple priorities under time constraints

Critically reviewed draft publications developed by other medical writers for clinical and editorial content

Consolidated and reconciled comments from authors, internal reviewers, and journal reviewers

Created figures, tables, graphs, and illustrations and managed their development by graphic design

Performed and documented PubMed literature searches

Ensured publication development process was compliant with internal SOPs, ICMJE guidelines, Good Publication Practice, FDA regulations, etc.

RESEARCH EXPERIENCE

Charité Hospital, Berlin, Germany, 07/2012–07/2014

Humboldt Postdoctoral Fellow, Institute of Clinical Physiology

Project: Elucidate the mechanisms regulating tight junction endocytosis and determine its contribution to inflammation-induced intestinal epithelial cell barrier dysfunction

Established an international collaboration with a leading research group in Berlin, designed a research project, and secured fellowship funding

Wrote a grant proposal for a collaborative project with an external research group and a material transfer agreement to obtain biologics from a US collaborator

Developed a protocol to isolate and quantitatively analyze endocytosed proteins

Prepared and presented research findings at international conferences, departmental meetings, and internal lab discussions

Provided writing and editorial support to colleagues for manuscripts, grant proposals, and presentations

Supervised 2 research technicians and provided training in research methodology

Pfizer Pharmaceutical Company, Cambridge, MA, 06/2011–06/2012

Postdoctoral Fellow, Immunology and Inflammation Department

Project: Characterized the global and inflammation-induced expression and enzymatic activity of Vanin-1; and identified cellular targets of Vanin-1 involved in immune cell activation and oxidative responses

Contributed to a cross-functional team for drug development and target validation

Proactively restructured research plan to maximize efficiency when human samples were limited

Initiated and co-wrote a company postdoctoral manual to help new postdocs transition into the company

Taught an introduction to confocal microscopy class to medical students at Boston University

Gained knowledge of drug discovery, development, and approval processes through postdoc discussion groups, research seminars, and discussions with mentors and team members

Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 05/2005–12/2010

Graduate Student, Division of Allergy and Immunology

Dissertation: Mast cell-mediated intestinal barrier function in homeostasis and disease

Developed, executed, and managed 2 projects that established a new research focus for the lab

Performed comprehensive literature and internet research to support every stage of the projects

Designed novel methods to analyze barrier function and enteric nerve activity in ex vivo intestine

Selected capital equipment and negotiated with vendors to save money

Invited to Children’s Hospital in Boston to train a research group on the methodology I developed

Mentored junior graduate students, providing training in research techniques and support in planning and data interpretation

Freie University, Berlin, Germany, 07/2001–07/2002

Fulbright Research Fellow, Institute for Neurobiology

Project: Examined neuronal activity and identified biochemical signaling processes activated during olfactory memory formation and recall in honeybees

Conducted research within a diverse group of international scientists

Edited manuscripts written by non-native English-speaking colleagues

University of Cincinnati College of Medicine, Cincinnati, OH, 08/2000–05/2001

Student Researcher, Department of Cellular and Molecular Biology- Neuroscience

Project: Examined the temporal expression of the gene, clock, in the suprachiasmatic nucleus of the hypothalamus and its regulation of circadian rhythms

NASA, Kennedy Space Center, FL, 06/2000–08/2000

Spaceflight and Life Sciences Intern

Project: Analysis of factors regulating hydroponic plant growth

Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 06/1997–08/1998

Howard Hughes Intern, Department of Pediatric Surgery

Project: Role of epidermal growth factor in intestinal adaptation following small bowel resection

CLINICAL AND MEDICAL EXPERIENCE

Bethesda North Hospital, Cincinnati, OH, 10/2010–05/2011

Clinical Research Assistant, TriHealth Hatton Research Institute

Topic: Improving quality of life for chronic obstructive pulmonary disease patients by utilizing palliative care

Collected, translated, and analyzed patient data

Sächsischen Hospital for Psychiatry and Neurology, Rodewisch, Germany, 03/2004–06/2004

Neurology Clinical Intern

University of Cincinnati College of Medicine, Cincinnati, OH, 08/2002–12/2010

Physician Scientist Training Program (MD/PhD Program)

Didactic medical training: clinical reasoning, pharmacology, anatomy, physiology, pathology, brain and behavior, microbiology, medical biochemistry, genetics, medical histology

Trained in clinical skills, and patient history and physical exams

Family Medicine clinical clerkship: Patient First, Cold Spring, KY

Prepared and presented an in-depth clinical case study at 2 national conferences

Crossroad Health Center, Cincinnati, OH, 03/2000–01/2001

Volunteer, Health Clinic

University Hospital, Cincinnati, OH, 09/1998–05/1999

Clinical Research Associate, Department of Emergency Medicine

Topic: Serum marker evaluation as a potential aid in diagnosing acute ischemic stroke; and assessment of the prognostic utility of Holtor monitoring versus cardiac enzymes in patients with ischemic chest pain

EDUCATION

Physician Scientist Training Program (MD/PhD)

University of Cincinnati College of Medicine, Cincinnati, OH

Didactic Protion of MD (years 1-2), 2003-2005

Ph.D. Immunobiology, December 2010

B.S. Biology, minor: Chemistry, Cum Laude, May 2001

Xavier University, Cincinnati, OH

RESEARCH GRANTS AND FELLOWSHIPS

Alexander von Humboldt Postdoctoral Fellowship, Berlin, Germany, 2012–2014

NIH/NIDDK NRSA Predoctoral Training Grant (F30DK082113-01), 2008–2011

NIH-funded Physician Scientist Training Program, University of Cincinnati College of Medicine, 2002–2010

Fulbright Research Fellowship, Berlin, Germany, 2001–2002

Howard Hughes Initiative in Biology Fellowship, Cincinnati Children’s Hospital Medical Center, 1997

SELECTED AWARDS AND RECOGNITIONS

MD/PhD Gastroenterology Workshop Travel Grant, American Gastroenterological Association, 2010

Outstanding Research Presentation Award, Physician Scientist Training Program Annual Meeting, 2008

Fellow-in-Training Travel Scholarship, American Academy of Allergy, Asthma, and Immunology Annual Meeting, 2006, 2007 and 2008

Research Presenter Scholarship, Keystone Symposia, 2007

Travel Grant, National MD/PhD Student Conference, 2007

Strategic Training in Allergy Research Award, American Academy of Allergy, Asthma and Immunology, 2006

Trustee Scholarship, Xavier University, 1998–2001

BS/MD Dual Admissions Program, Xavier University and University of Cincinnati College of Medicine, 1998

Outstanding Student Researcher Award, Sigma Xi, 1998

PROFESSIONAL ACTIVITIES

Member, Physician Scientist Promotion Board, University of Cincinnati College of Medicine, 2008–2009

Member, Graduate Student Grievance Committee, University of Cincinnati College of Medicine, 2009

Member, Physician Scientist Academic Appeals Board, University of Cincinnati College of Medicine, 2006–2008

Tutor, immunology, pathology, and microbiology, University of Cincinnati College of Medicine, 2005–2006

Leader, pharmacology discussion groups, University of Cincinnati College of Medicine, 2005–2007

Member, Student Health Services Appeals Committee, University of Cincinnati College of Medicine, 2004–2005

Volunteer, Contact Center, Cincinnati, OH, 2004–2005

PUBLICATIONS

Peer Reviewed Articles

Groschwitz KR, Wu D, Osterfeld H, Ahrens R, Hogan SP. Chymase-mediated intestinal epithelial permeability is regulated by a protease-activating receptor/matrix metalloproteinase-2-dependent mechanism. Am J Physiol Gastrointest Liver Physiol. 304(5):G479, 2013.

Ahrens R, Osterfeld H, Wu D, Chen CY, Arumugam M, Groschwitz K, Strait R, Wang YH, Finkelman FD, Hogan SP. Intestinal mast cell levels control severity of oral antigen-induced anaphylaxis in mice. Am J Pathol. 180(4):1535, 2012.

Wu D, Ahrens R, Osterfeld H, Noah TK, Groschwitz K, Foster PS, Steinbrecher KA, Rothenberg ME, Shroyer NF, Matthaei KI, Finkelman FD, Hogan SP. Interleukin-13 (IL-13)/IL-13 receptor alpha 1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent CL- secretion. J Biol Chem. 286(15):13357, 2011.

Han X, Gilbert S, Groschwitz K, Hogan S, Jurickova I, Trapnell B, Samson C, Gully J. Loss of GM-CSF signaling in non-haematopoietic cells increases NSAID ileal injury. Gut. 59(8):1066, 2010.

Munitz A, Cole ET, Beichler A, Groschwitz K, Ahrens R, Steinbrecher K, Wilson T, Han X, Denson L, Rothenberg ME, Hogan SP. Paired immunoglobulin-like receptor B (PIR-B) negatively regulates macrophage activation in experimental colitis. Gastroenterology. 139(2):530, 2010.

Groschwitz KR, Ahrens R, Osterfeld H, Gurish MF, Han X, Abrink M, Finkelman FD, Pejler G, Hogan SP. Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism. Proc Natl Acad Sci USA. 106(52):22381, 2009.

Herbert DR, Yang JQ, Hogan SP, Groschwitz K, Khodoun M, Munitz A, Orekov T, Perkins C, Wang Q, Brombacher F, Urban JF Jr, Rothenberg ME, Finkelman FD. Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection. J Exp Med. 206(13):2947, 2009.

Han X, Ren X, Jurickova I, Groschwitz K, Pasternak BA, Xu H, Wilson TA, Hogan SP, Denson LA. Regulation of intestinal barrier function by signal transducer and activator of transcription 5b. Gut. 58(1):49, 2009.

Groschwitz K, Forbes EE, Abonia JP, Brandt EB, Cohen E, Blanchard C, Ahrens R, Seidu L, McKenzie A, Strait R, Finkelman FD, Foster PS, Matthaei KI, Rothenberg ME, Hogan SP. IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity. J Exp Med. 205(4):897, 2008.

Hogan SP, Seidu L, Blanchard C, Groschwitz K, Mishra A, Karow ML, Ahrens R, Artis D, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rothenberg ME. Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility. J Allergy Clin Immunol. 118(1):257, 2006.

Shin CE, Falcone RA Jr, Duane KR (Groschwitz), Erwin CR, Warner BW. The distribution of endogenous epidermal growth factor after small bowel resection suggests increased intestinal utilization during adaption. J Pediatr Surg. 34(1):22, 1999.

Shin CE, Helmrath MA, Falcone RA Jr, Fox JW, Duane KR (Groschwitz), Erwin CR, Warner BW. Epidermal growth factor augments adaptation following small bowel resection: optimal dosage, route and timing of administration. J Surg Res. 77(1):11, 1998.

Invited Review Article

Groschwitz KR, Hogan SP. Intestinal barrier function: molecular regulation and disease pathogenesis. J Allergy Clin Immunol. 124(1):3, 2009.

Conference Abstracts

Groschwitz K, Ahrens R, Osterfeld H, Finkelman F, Rothenberg M, Abrink M, Pejler G, Hogan S. Mast cell chymase regulates homeostatic intestinal barrier function. J Allergy Clin Immunol. 123(2):S215, 2009.

Wu D, Ahrens R, Groschwitz K, Osterfeld H, Foster P, Finkelman F, Matthaei K, Hogan S. Elevated intestinal interleukin-13 promotes intestinal epithelial barrier dysfunction. J Allergy Clin Immunol. 123(2):S186, 2009.

Groschwitz K, Ahrens R, Finkelman F, Abonia J, Gurish M, Hogan S. Role for mast cell chymase in intestinal epithelial permeability. J Allergy Clin Immunol. 121(2):S110, 2008.

Groschwitz KR, Forbes EE, Brandt EB, Ahrens RE, Abonia JP, Finkelman FD, Rothenberg ME, Hogan SP. Intestinal Expression of Interleukin-9 (IL-9) Induces Mast Cell-Mediated Intestinal Permeability. J Allergy Clin Immunol. 119(1):S313, 2007.

Forbes E, Groschwitz K, Ahrens R, Brandt E, Rothenberg M, Foster P, Matthaei K, Hogan S. Role of Th2-molecules in OVA-Induced Intestinal Anaphylaxis. J Allergy Clin Immunol. 119(1):S136, 2007.

Groschwitz K, Forbes E, Brandt E, Matthaei K, Hogan S. Intestinal Peristaltic Reflex (IPR) is Regulated by Mast Cells and IL-9. J Allergy Clin Immunol. 117(2):S271, 2006.

PRESENTATIONS

National and International Conferences

Groschwitz KR. Schumann M, Schulzke JD. VEGF-Induced Endocytosis of Intestinal Epithelial Tight Junction Proteins. Poster, International Meeting of the German Society for Cell Biology, Leipzig, Germany, 2012.

Groschwitz KR, Fleming M. Vanin-1 Drives Inflammatory and Oxidative Responses in vitro and in vivo. Poster, Pfizer Worldwide R&D Annual Postdoc Symposium, Groton, CT, 2011.

Groschwitz KR, Ahrens R, Osterfeld H, Finkelman F, Rothenberg M, Abrink M, Pejler G, Hogan S. Mast cell chymase regulates homeostatic intestinal barrier function. Oral presentation, American Academy of Allergy, Asthma, and Immunology Annual Meeting, Washington DC, 2009.

Groschwitz KR, Ahrens R, Finkelman F, Abonia J, Gurish M, Hogan S. Role for Mast Cell Chymase in Intestinal Epithelial Permeability. Oral presentation, American Academy of Allergy, Asthma, and Immunology Annual Meeting, Philadelphia, PA, 2008.

Groschwitz KR, Forbes EE, Brandt EB, Ahrens RE, Abonia JP, Finkelman FD, Rothenberg ME, Hogan SP. Intestinal Expression of Interleukin-9 Induces Mast Cell-Mediated Intestinal Permeability. Oral presentation, Keystone Symposia on Mast Cells, Basophils, and IgE, Copper Mountain, CO, 2007.

Groschwitz KR, Forbes EE, Abonia JP, Finkelman FD, Rothenberg ME, Hogan SP. Interleukin-9-Induced Mast Cell-Mediated Intestinal Permeability. Poster, Medical Scientist Training Program- National MD/PhD Student Conference, Keystone, CO, 2007.

Groschwitz KR, Forbes EE, Brandt EB, Ahrens RE, Abonia JP, Finkelman FD, Rothenberg ME, Hogan SP. Intestinal Expression of Interleukin-9 Induces Mast Cell-Mediated Intestinal Permeability. Oral presentation, American Academy of Allergy, Asthma, and Immunology Annual Meeting, San Diego, CA, 2007.

Groschwitz KR, Forbes EE, Brandt EB, Matthaei KI, Rothenberg ME, Hogan SP. A Role for Mast Cells and IL-9 in the Intestinal Peristaltic Reflex. Oral and poster presentation, American Academy of Allergy, Asthma, and Immunology Annual Meeting, Miami Beach, FL, 2006.

Groschwitz KR, Bradley D, Coberly L, Feinberg J. Flashback From the Past: HIV Presenting as Kaposi’s Sarcoma. Poster, Society of General Internal Medicine Meeting, Chicago, IL, 2004.

Groschwitz KR, Bradley D, Coberly L, Feinberg J. Flashback From the Past: HIV Presenting as Kaposi’s Sarcoma. Poster, American College of Physicians Scientific Meeting, Columbus, OH, 2004.

Local Meetings

Groschwitz KR. Regulation of Intestinal Epithelial Barrier Function via PAR-2/MMP-2-Dependent Mechanisms. Oral presentation, Center for Immunological Research Forum, Cincinnati, OH, 2010.

Groschwitz KR. Mast Cell/mMCP-4-Mediated Homeostatic Intestinal Barrier Function. Oral presentation, Center for Immunological Research Forum, Cincinnati, OH, 2009.

Groschwitz KR. Mast Cell Regulation of Intestinal Barrier Function in a Murine Model of Food Allergies. Oral presentation, Physician Scientist Training Program Annual Meeting, Cincinnati, OH, 2009.

Groschwitz KR. Mast Cell-Mediated Intestinal Permeability. Invited speaker, Barrier and Fluxes, Cincinnati, OH, 2008.

Groschwitz KR. Mast Cell Regulation of Homeostatic Intestinal Barrier Function by Chymase/mMCP-4. Oral presentation, Center for Immunological Research Forum, Cincinnati, OH, 2008.

Groschwitz KR. Mast Cell-Mediated Breakdown of Intestinal Epithelial Barrier Function. Oral presentation, Physician Scientist Training Program Annual Meeting, Cincinnati, OH, 2008.

Groschwitz KR. Mast Cell-Mediated Intestinal Epithelial Permeability. Oral presentation, Center for Immunological Research Forum, Cincinnati, OH, 2008.

Groschwitz KR, Forbes EE, Brandt EB, Ahrens RE, Abonia JP, Finkelman FD, Rothenberg ME, Hogan SP. Interleukin-9-Induced Mast Cell-Mediated Intestinal Permeability. Poster, Digestive Health Center: Bench-to-Bedside Research in Pediatric Disease Research Forum, Cincinnati, OH, 2007.

Groschwitz, KR. Role for Mast Cells in the Regulation of Intestinal Permeability. Oral presentation, Center for Immunological Research Forum, Cincinnati, OH, 2007.

Groschwitz KR. Intestinal Expression of Interleukin-9 Induces Mast Cell-Mediated Intestinal Anaphylaxis. Oral presentation, Physician Scientist Training Program Annual Meeting, Cincinnati, OH, 2007.

Groschwitz, KR. Intestinal Expression of Interleukin-9 Induces a Mast Cell-Mediated Intestinal Permeability. Oral presentation, Immunobiology Student/Postdoc Symposium, Cincinnati, OH, 2007.

Groschwitz KR, Forbes EE, Brandt EB, Ahrens RE, Abonia JP, Finkelman FD, Rothenberg ME, Hogan SP. Mast Cell-Mediated Intestinal Permeability. Poster, University of Cincinnati Graduate Student Research Forum, Cincinnati, OH, 2006.

Groschwitz, KR. Intestinal Anaphylaxis Alters Gastrointestinal Function. Oral presentation, Immunobiology Student/Postdoc Symposium, Cincinnati, OH, 2006.

Groschwitz KR. Intestinal Anaphylaxis: Mast Cell-Mediated Changes. Oral presentation, Physician Scientist Training Program Annual Meeting, Cincinnati, OH, 2006.

Groschwitz KR. The Neuronal Activity Elicited by Different Odors in the Honey Bee. Invited Speaker, Xavier University, Cincinnati, OH, 2002.

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