RYAN L. SIZEMORE

St. Charles, MO ***** 314-***-****

ac4jq4@r.postjobfree.com www.linkedin.com/in/ryan-sizemore

SENIOR QUALITY SCIENTIST

Detail-Oriented Molecular Biologist

Experienced quality scientist working in the fields of biochemistry, biotechnology and IT who is excited to improve the world through hard work. Life-long passion for science, utilizing data to provide solutions. Committed to industry, works well independently or as part of a collaborative team. Areas of expertise:

Validation (Assay, Equipment, Environment)

End-point and RT PCR

High-throughput DNA & Protein Extraction

Electrophoresis

Quality Auditing

21 CFR working knowledge

IQ, OQ, PQ

HPLC, Empower Pro

Quality Management, CAPA

ELISA, SPARCL, Conjugation

TECHNICAL SKILLS

IT – SAP, Beckman LIMS, Labware LIMS, Thermo Fisher LIMS, LGC Kraken LIMS, Empower Pro, TaqPro, Orion

Microsoft Office, JMP, Minitab, ELN (Electronic Lab Notebook), Spotfire

PROFESSIONAL EXPERIENCE

Crystal Clean, St. Louis, MO

Business partner in a small cleaning company (2016-present)

Clean homes and businesses per the client’s specifications.

Schedule and document day to day business activities based on client needs, most efficient routes, etc.

Manage supply inventory and assist in resolving personnel issues.

Monsanto, St. Louis, MO

A world leader in agriculture with more than 20,000 employees dedicated to molecular biology to create better seeds with desirable traits and crop protection to create solutions to protect plant health with minimal environmental impact.

Research Scientist/Project Manager for QA/QC – Molecular Biologist (2008 to 2016)

Selected to serve in a team of 4 scientists to develop, implement and monitor analytical methods for global Quality Assurance/Quality Control (QA/QC) labs in the production technology sector of Monsanto. Duties included global continuous improvement projects, assay development, method development and training, validation, proficiency testing, and other tasks. Agility was key in this role as priorities constantly changed.

Developed, validated, implemented and maintained high-throughput analytical methods globally, determining genetic purity in Agricultural (AG) products.

Led trait purity by DNA platform assay development and implementation, saving $1.1M annually by utilizing this combinational testing strategy.

Coordinated global validation and proficiency testing (PT) programs, including (USDA, GIPSA, ISTA and internal PTs) for QA/QC labs. Developed program that granted labs’ data international acceptance through ISO 17025 accreditation, ISTA and USDA.

Cross-trained and audited the Seed/Protein Analytics HPLC group in Monsanto Regulatory.

Established certified reference material qualifications and library, providing qualified material to Monsanto’s 9 QA/QC labs, regulatory science and any 3rd-party request for material.

Provided oversight and troubleshooting for any assay issues that arose for implemented Standard Operating Procedures (SOPs), minimizing downtime in high-throughput labs.

Developed, validated and implemented globally new, robust, high-throughput DNA extraction methods, allowing miniaturization of PCR reaction volumes to 800 nanoliters while improving data quality.

Ryan L. Sizemore ac4jq4@r.postjobfree.com Page 2

Research Scientist for QA/QC – Molecular Biologist (continued)

Contributed to Monsanto emergency response team, handling news headline type emergencies. One example of this team’s function was averting USDA shutdown of wheat export from US graineries in 2016. This may have saved Monsanto $40M/day in liability, pending litigation.

Worked as project lead for design and validation of production technology lab environment in North America, supporting ~100M data points annually.

Participated in Monsanto Scientific Review Working Group (SRWG), accepting or rejecting 3rd-party experiments from companies, universities and independent researchers.

Partnered with AEIC (Analytical Excellence through Industry Collaboration) working with all major players of global seed industry, meeting bi-annually to discuss direction of test methods and quality.

Served as quality management system consultant for QA/QC labs, maintaining global accreditations and certifications.

Mentored colleagues in personal and professional development as well as long-term goal setting, ensuring career success.

Quality Manager (2003 to 2009)

Served as quality manager for Monsanto Ag manufacturing in addition to running PCR lab. Developed ISO 17025 quality manual, SOPs, quality control documents and site-specific documents for ISO 17025 accreditation. Trained ISO deputies on proper auditing preparation, execution and documentation.

Led team that developed 17025 quality management system (QMS), obtaining ISO 17025 accreditation in 2005.

Maintained Ag manufacturing, achieving QMS, ISO 17025 accreditation with A2LA and 9001 certifications with SGS.

Performed root cause analysis, generated Corrective Action Reports (CARs) and Preventive Action Reports (PARs) as needed, produced change reports and preformed quality audits on external suppliers as well as internal sites.

Quality Control – PCR (AP) Lab Manager (2001 to 2008)

Supervised day-to-day lab activities of PCR lab. Managed sample volumes, on-boarding of new employees and contractors. Coordinated high-throughput AP-testing lab for AG manufacturing. Ran PCR, ELISA and SNP assays. Served as certified management representative (CMR) for genetic purity lab.

Performed super-standard production, customizing oligonucleotide QC operations.

Organized lab validation programs, improving proficiency testing experiments and control documents.

Managed reference seed inventory using custom software, ensuring adequate supplies were available.

Trained contractor and full-time personnel in ELISA, PCR and gel-electrophoresis techniques, ensuring best practices were followed.

Coordinated preventative maintenance program for lab automation and equipment, reducing downtime.

TODAY’S STAFFING, St. Louis, MO 2000 to 2001

Quality Assurance Lab Technician

Performed high-throughput Isozyme, ELISA and PCR testing. Prepared and extracted tissue samples that were used in genetic purity testing. Performed lab automation preventative maintenance, repair and programming.

Designed and developed ELISA purity testing lab from scratch, providing quality trait purity data to customers.

Implemented ELISA techniques, HRP Conjugations and improving efficiency and data quality for each procedure.

EDUCATION PROFESSIONAL DEVELOPMENT

Bachelor of Science (BS), Biology with focus in Biochemistry and Biotechnology

UNIVERSITY OF MISSOURI, Columbia and St. Louis, MO

Six Sigma Green Belt Training, 5S LEAN Certified

GRR, GLP and Quality Control Trained

Interstate Movement, Maintenance and Importation of Regulated Plant Material

ISO 17025 Auditor, ISO 9001 Auditor

Safety – Ergonaut, Safety Council, CPR/AED Child CPR and First Aid certified – Red Cross

COMMUNITY & VOLUNTEER ACTIVITIES

F.I.R.S.T. Robotics Championship 2014 to 2016 – Monsanto booth worker

Komen Race for the Cure team organizer, St. Louis, MO

Pet Therapy volunteer, Columbia, MO

JDRF Walk Volunteer

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