Data Assistant

ADITI PARANJPE

404-***-**** j *************@*****.*** j www.linkedin.com/in/aditi-paranjpe

**** ********* ** **, *******, Georgia 30318

EDUCATION

Georgia Institute of Technology, Atlanta, U.S. Aug 2016 - Dec 2017 MS, Bioinformatics GPA: 3.83/4.0

Bioinformatics Center, Pune University, Pune, India 2013 - 2015 M.Sc, Bioinformatics GPA: 5.12/6

EXPERIENCE

Georgia Institute of Technology, Atlanta, U.S.j Graduate Research Assistant Aug 2016 - Present Working under Dr. Kostas Konstantinidis in the area of metagenomic and evolutionary genomics

Developed a pipeline to analyze time-series metagenomic data for studying intra population diversity within microbial species.

The pipeline accepts metagenomic samples from different time points, conducts metagenomic assembly (IDBA-UD), binning

(MetaBat), variant calling(GATK) and the allele diversity change over time at each SNP position is quantified.

Analyzed 140 genomes from 6 years of Lake Lanier time-series metagenomic data consisting of 54 metagenomic samples. NCIM Resource Centre, NCL, Pune, India j Project Assistant Dec 2015 - Jun 2016

Metagenomic data analysis to explore bacterial diversity and gain functional insights from basaltic hot spring of Unkeshwar.

Studied effects of seasonal changes on hot spring microbial population from 8 years of time-series metagenomic data analysis.

Performed whole genome assemblies, annotation and comparative studies of microorganisms sequenced by NCIM. Persistent Systems Limited, Pune, India j Domain Analyst (Trainee) June 2015 - September 2015

Designed a pipeline for HPLC (High Performance Liquid Chromatography) data visualization using Perl and R.

Handled software testing and enhancement tasks.

PROJECTS

Comparative genomic analysis of Salmonella Heidelberg samples sequenced by CDC

Analyzed 26 Salmonella Heidelberg samples collected from 7 different regions of USA by CDC to classify them into different possible outbreak groups.

Conducted whole genome assembly, functional annotation and classification, phylogenetic analysis and pan-genomic studies. Study of differential gene expression in Autism Spectrum Disorder using RNA seq data analysis

Compared gene expression profiles of different brain regions of autistic patients from 12 RNA-seq samples using Cufflinks RNA-seq workflow.

Study of differential gene expression by GATA1 and GATA2 using ChIP-seq data analysis

Identified genes regulated by GATA1 and GATA2 in erythropoeitin pathway at different stages of cell differentiation. Exploring the essential factors responsible for age prediction of Abalone

Built an age prediction model for abalones(Sea snails) from 8 phenotypic features by stepwise regression and PCA in R. Web interface development for Monitoring Georgia Tech Energy Consumption

Monitoring daily energy consumption to detect unusually high energy usage using 10 years of GT energy consumption data.

Classified all GT building using K-means clustering and employed ANN based Nonlinear AutoRegressive network with eXoge- nous (NARX) for electric power load forecasting.

TECHNICAL SKILLS

OS Platforms Windows, Linux, Mac

Languages Shell Scripting, Perl, Python, R, MATLAB, SQL, Scala Next Generation Sequence Analysis ChIP-seq, RNA-seq, microarray, metagenomics, 16S rRNA,whole genome analysis Computational Genomics Genome assembly, read mapping, gene prediction, annotation, variant calling Visualization Circos, Cytoscape, IGV, CGView, JBrowse, Mauve, D3 Databases ExAC, ClinVar, NCBI, Ensemble, KEGG, OMIM Software Test Management HP QC, JIRA

PUBLICATIONS

Gohil KN, Neurgaonkar PS, Paranjpe AS, Dastager SG, Dharne MS. Peeping into Genomic architectureby resequencing of Ochrobactrum intermedium M86 strain during laborayory adapted conditions. Genomics Data 2016 Jun;8:72-76. Mehetre GT, Paranjpe AS, Dastager SG, DharneM. Investigation of microbial diversity in geothermal hot spring of Unkeshwar, India based on 16S rRNA amplicon metagenome sequencing. Genome Announcements. 2016 Jan-Feb 4(1):e01766-15. Mehetre GT,Paranjpe AS, Dastager SG, Dharne M. Complete metagenome sequencing based bacterial diversity and functional insights from basaltic hot spring of Unkeshwar, Maharashtra, India. Genomics Data 7 (2016) 140143

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