Email ID: email@example.com
Ph no: +1-858-***-****
Seeking a highly challenging and escalation oriented career to work as a researcher with profound professional experts to the optimum use of my knowledge and strong research skills in the field of Biotechnology.
Aug 2015 – May 2017
Department of Physics and Nanotechnology
2011- 2015 Ph.D. Nanotechnology
Anna University, Chennai- 600 025
Research Supervisor: Dr. T. Devasena
Title of thesis: Ameliorating effect of quercetin loaded poly(d,l-lactide) nanoparticles
against coal fly ash nanoparticles-induced toxicity
The source, generation, characterization and the toxicity of ambient particulate matter is an active area of research. There are only few in vitro and in vivo studies were conducted on the toxicity of coal fly ash (CFA) particles. This area requires further extensive examination, since earlier studies have not adequately considered the CFA particle characteristics and mechanistic aspect of the CFA-induced toxicity, in the in vitro and in vivo models. Due to its extensive production and wider application there is a heavy discharge of coal fly ash nanoparticles (CFA-NPs) into the atmosphere and it is a potential risk to living organisms. There is a growing interest in the toxicity of CFA-NPs and their significance in relation to human health. It is already known from the previous literatures that the exposure to particulate matter leads to severe adverse effects. This interest encouraged us to investigate the toxicity response using in vitro and in vivo models for understanding the mechanism of action and its functional response to CFA-NPs. Hence, the study is focused on the collection of nanosized CFA, characterization and their toxicity evaluation at molecular and genetic level in terms of cytotoxicity, oxidative DNA damage and mutagenicity in cell cultures. We have investigated the CFA-NPS toxicity via dermally and intratracheally in animal models. Also we have evaluated the ameliorating effect of quercetin-loaded PLA-nanoparticles against CFA-NPs-induced toxicity in vitro and in vivo.
2009-2011 MS., Biotechnology
University of Essex,
Title of thesis: Over-expression, purification and characterization of two mutant forms
ofdecaheam C-type cytochrome Pcc35 from Shewanellafrigidimarina
2005 – 2009 B.Tech., Biotechnology
Chennai – 600069, Tamil Nadu, India
Title of thesis: Standardization of culture methods for the production of methane from
Have done a mini project on the topic ‘Effect of medium on the production of Pectinase Enzymes’, at Asthagiri Herbal research Foundation.
1.BharathiSambandam, EganathanPalanisami, RajasekarAbbugounder, Balakrishna Murthy Prakhya&DevasenaThiyagarajan 2014, ‘Characterizations of coal fly ash nanoparticles and induced in vitro toxicity in cell lines’, Journal of nanoparticles research, vol. 16, pp. 2217-2226.
2.BharathiSambandam, Villianur Ibrahim Hairul Islam, Pachaiappan Raman, Manish Bhattacharjee, AbinayaBalasubraminium&DevasenaThiyagarajan 2014, ‘Coal fly ash nanoparticles induced cytotoxicity and oxidative DNA damage and apoptosis in Chang liver cells’. African Journal of Pharmacy and Pharmacology, vol. 8, no. 32, pp. 801-808.
3.Durga Mohan, BharathiSambandam, Balakrishna Murthy Prakhya&DevasenaThiyagarajan 2015, ‘Characterization and Phytotoxicity Studies of Suspended Particulate Matter (SPM) in Chennai Urban Area’, Journal of environmental biology, vol. 36, pp. 583-589.
4.BharathiSambandam, Villianur Ibrahim Hairul Islam, Balkrishna Murthy Prakhya&DevasenaThiyagarajan 2015, ‘Characterizations of coal fly ash nanoparticles and induced in vitro cellular toxicity and oxidative DNA damage in different cell lines’, Indian Journal of Experimental Biology, vol. 53, pp. 585-593.
5.BharathiSambandam, Satheshkumar S, ArivarasanAyyaswamy, NagarjunaYadav BV &DevasenaThiyagarajan 2015, ‘Synthesis and characterization of Poly D-L Lactide (PLA) nanoparticles for the delivery of quercetin’. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no.5, pp. 42-49.
6.BharathiSambandam, Durga Mohan, PazhanivelKaliyaperumal, Pachaiappan Raman &DevasenaThiyagarajan 2015, ‘Acute dermal toxicity of coal fly ash nanoparticles in vivo’. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no.7, pp. 403-407.
7.BharathiSambandam, DevasenaThiyagarajan, ArivarasanAyyaswamy& Pachaiappan Raman 2016, ‘Extraction and isolation of flavonoid quercetin from the leaves of trigonellafoenum-graecum and their anti-oxidant activity’. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 8, no. 6, pp.120-124.
8.HarithalakshmiVenkatasamy, ArivarasanAyyaswamy, Pachaiyappan Raman, JaidevKulasekaran, DevasenaThiyagarajan & BharathiSamabandam 2016, ‘Antibacterial and antioxidant activities of green synthesized silver nanoparticles using rotalarotundifolia plant extracts’ Advanced science Engineering and Medicine, Vol. 8, no. 12, pp. 947-953.
1.BharathiSambandam, Kartikeyan V 2007, ‘Effects of Sodium chloride and House hold Syntheteic waste’, Presented in National seminar on current biotechnology and microbiology research during 7thto 9thMarch 2007 held at AyyaNadarJanakiAmmal College, Sivakasi.
2.BharathiSambandam, Gopinath KP 2007, ‘Study of annexene gene transfer in tomato plants’, presented in Genespire 07 A national level technical symposium on 29thSeptember 2009 held at Kumaraguru college of Technology, Coimbatore.
3.BharathiSambandam, Rathi R 2008 ‘Study on the antitumor effect of Paclitaxel in liver of breast cancer bearing experimental rats’, presented in National conference on recent trends in chemical engineering in National technical conference during 2ndto 4thApril 2008 held at St.Peters engineering college, Avadi, Chennai.
4.BharathiSambandam, Gopinath KP 2008 ‘Pebbles and Nanosensors’, presented in One day seminar on recent trends & challenges in biosciences on 6thFebruary 2008 held at Asan Memorial college, Chennai.
5.BharathiSambandam, Gopinath KP 2008 ‘Delaying of ripening of Tomato fruits using ethanol vapour system’ presented in One day seminar on recent trends & challenges in biosciences on 6thFebruary 2008 held at Asan Memorial college, Chennai.
6.BharathiSambandam, AbbuRajasekar&DevasenaTagarajan 2013, ‘Characterizations of coal fly ash nanoparticles and their in vitro toxicity in cell lines’, Presented in Second international workshop on advanced functional nanomaterials (SIWAN) during 28thto 30thJanuary 2013 held at Anna University, Chennai.
7.BharathiSambandam, AbbuRajasekar&DevasenaTagarajan 2013, ‘Characterizations of Coal fly ash nanoparticles and induced in vitro toxicity in cell lines’, Presented in Nanobio 2013 Collaborative international conference during 27thto 29thJune 2013 held at Anna University, BIT campus, Tiruchirapalli.
8.BharathiSambandam, AbbuRajasekar&DevasenaTagarajan 2014, ‘Characterization of Coal Fly Ash Nanoparticles and Induced in vitro Cellular Toxicity and Oxidative DNA damage’, presented in 6th International Conference on Nanoscience and Technology (ICONSAT) during 2ndto 5thMarch 2014 held at Institute of Nanoscience and Technology, Chandigarh.
9.BharathiSambandam, Villianur Ibrahim Hairul Islam, Balakrishna Murthy Prakhya&DevasenaThiyagarajan 2014, ‘Characterization of coal fly ash nanoparticles and in vitro induced oxidative DNA damage and apoptosis in Chang liver cell lines’, presented in International conference on materials and characterization techniques (ICMCT) during 10thto 12thMarch 2014 held at VIT University, Vellore.
10.BharathiSambandam & ShunmugaPriya S 2017, ‘Synthesis of gold nanoparticles using quercetin and preparation of beta glucan loaded nanofibers for wound healing applications’, presented in international conference on nanoscience and nanotechnology (ICONN 2017) during 9th August to 11th August held at SRM University, Kattankulathur.
1.Participated in Chennai Science Festival-2009 on 19th& 22ndFebruary 2009, organized by Department of higher education, Govt. of Tamilnadu.
2.Two days workshop on Biotechnology and your career on 4th& 5thJuly 2007, organized by Department of higher education, Science city, Chennai-25.
3.Three days workshop on 23rd National congress of parasitology from 18thto 20thNovember 2011, organized by Centre for Biotechnology, Anna University, Chennai-25.
4.One day workshop on ATOM probe tomography on 9thJanuary 2012, organized by Department of Metallurgical and Materials Engineering, IIT madras.
5.Participated in Chennai Science Festival-2012 from 27thto 30thJanuary 2012, organized by Department of higher education, Govt. of Tamilnadu.
6.Participated in National seminar on “Indigenous Nanomaterials Development for Industrial Applications” (INDIA) on 27thand 28thFebruary 2012, organized by Centre for Nanoscicenceand Nanotechnology, Anna University, Chennai-25.
7.Two days seminar on Issues in preparing research thesis and project proposal from 16thand 17thMarch 2012, organized by Department of industrial engineering, Anna University, Chennai-25.
8.Participated in National seminar on “Recent Trends in Nanobiotecnology on 19th& 20thSeptember 2013, organized by Centre for Nanoscicenceand Nanotechnology, Anna University, Chennai-25.
9.Participated and exhibited in the “Technology Exhibition” on 13th& 14thMay 2013 organized by Centre for Technology Development and Transfer, Anna University, Cennnai-25.
1.Undergone inplant training in “Pepsi Co,(Pvt)” Ltd.Mammandur.
2.Undergone inplant training in “Mohan Breweries and distilleries”, Vedanarayanapuram.
3.Undergone inplant training regarding ‘Use of enzymes in leather processing’ at Central Leather Research Institute, Adyar Chennai-25.
4.Undergone inplant training in “Jo Geo Leather Enterprise”, Guduvanchery.
5.Undergone inplant training in “Omega Metal and Water Testing Lab”, Guindy.
6.Undergone inplant training in “Centre for Applied Research and Development”, NLC, Neyveli.
EXPERIENCE IN CHARACTERIZATION TECHNIQUES
X-ray Diffraction analysis (XRD)
Particle Size Analyzer (PSA)
Preparation of scaffolds using Electro-spinning, Cloning and expression techniques, Protein purification, labeling and analysis, Bioprocess techniques, Basic cell culture experiments, Animal studies, Immunological assays, Biochemical tests and Toxicity assays.
DATA ANALYZING TOOLS
Graph Prism, Origin, SPSS
GUIDANCE IN THESIS
Master in Nanotechnology: 2
Bachelors in Nanotechnology: 4
1.Dr. R. JAYAVEL
Professor and Director
Centre for Nanoscience and Technology
Anna University, Chennai- 600 025
Contact No: +91-944**-*****
E mail: firstname.lastname@example.org
2.Dr. T. DEVASENA
Centre for Nanoscience and Technology
Anna University, Chennai- 600 025
Contact No: +91-44-223*-****
Department of Biotechnology
School of Bioengineering
Contact No: +91-948*******
Name : BharathiSambandam
Date of Birth : 10-24-1987
Sex : Female
Nationality : Indian
Languages known : English, Tamil
Address : 9155 Judicial Drive, Apt No.5427
San Diego, CA-92122
Ph.No.(mob) : +1-858-***-****
I hereby declare that the above mentioned information is correct to the best of my knowledge and belief.