Medical Research

Curriculum Vitae

Name: Dr. (Mrs) Subodhini Anant Abhang

Designation: Professor,

Retired From :Department of Biochemistry,

B. J. Medical College and Sassoon General Hospital,

Pune.

Date of Birth: 18th March 1953.

Complete postal address: Apurva Apartment,

Tapodham Road,

Warje, Pune - 411 058.

Telephone (M): 996*******

e-mail: *********.******@*****.***

Nationality: Indian.

Languages known: English, Hindi, Marathi.

Educational Qualification:

Degree University/Institution Field Year

B.Sc. Dr.BabasahebAmbedkarMarathwada University, Chemistry 1973

Aurangabad.

M.Sc. Dr.BabasahebAmbedkarMarathwada University, Biochemistry 1975

Aurangabad.

Ph.D. Dr.BabasahebAmbedkarMarathwada University, Medical 1984

Aurangabad Biochemistry

Research/ Training experience:

Investigator in clinical trial unit of HIV networks funded by NIH, USA in collaboration with JohnsHopkinsUniversity, Baltimore, USA [Since 2008].

Recognized PhD Guide of Maharashtra University of Health Sciences, Nashik [Since 2008]:

At present 8 students are working under my guidance for PhD (2 has submitted)

Ongoing Research Projects:

1.Comparative proteomics of breast cancer: Abnormal expression of proteins [2010].

2.Effect of chemotherapy on factors regulating apoptosis in breast cancer [2010].

3.Study the metabolic role of Adipokines, micronutrients, anthropometric measurements and birth weight in relation to insulin resistance in the (age group 10-20 year) [2010].

4.Predictive values of biochemical markers in sepsis [2010].

5.Study of aldose reductase, oxidative stress and dietary antioxidants in diabetic cataract [2009].

Recognized PG Teacher for M.D. Biochemistry of MaharashtraUniversity of Health Sciences, Nashik [Since 2006].

Research project completed [2007-2010]:

Comparison of oxidative stress and dietary antioxidant status in benign and malignant tumors of the breast.

Research project underway [2010]:

1)Estimation of serum arginase level in acute coronary syndrome patients.

2)Study of asymmetric dimethyl arginine in patients of coronary artery disease.

3)Renal disorder.

Recognized PG Teacher for M.D. Biochemistry and M.Sc. Medical Biochemistry of PuneUniversity [Since 1986].

Research project completed [1996-99]:

Arginase as a prognostic marker during chemotherapy.

Worked as External Referee for Ph.D degree:

Evaluated Ph.D. thesis entitled “Studies on Mammalian Oviductal Glycoprotein”

Training programs attended:

Participated in workshop on Good Clinical Laboratory Practices held on July 2010.

Attended a basic course in cancer research-“Introducing clinicians to basic research” at Advance Center for Treatment, Research and Education in Cancer, Karghar, Navi Mumbai on 16th and 17th Sept 2006.

Workshop on “Newer Analytical Techniques” in clinical ATCC 2003, organized by Armed Forces Medical College, Pune from 9th Oct. 2003.

Participated in the workshop organized by MUHS on “ Research Methodology”

Research Specialization:

Cancer and chemotherapy.

Clinical and molecular biochemistry.

Immunology.

Infectious diseases.

A book chapter is written in “Advances in clinical chemistry” on topic “Apoptosis markers in breast cancer therapy”.

Total publications : 29 (Refer annexure I for details)

Reviewer for many journals : Clin chim acta, Euro J of cancer.

Co-editor for : 1) Journal of Medical Research

2) International journal of sport,exercise and health research

Annexure I

Important publications ( with titles and references):

Papers published in National journals:

1.S.A.Abhang, S.N.Jangle, I Vaishwaner Serum Arginase activity in infective hepatitis . Medical journal of Western India 1985 .vol.13 pp.

2.Mrs. A.M. Kulkarni,Dr .S A. AbhangComputers in clinical laboratories . Maharastra Medical Journal. Jan. 1989. Vol. XXXVI No. 1.

3.S.A.Abhang, P.M.Bulakh. The effect of Arginine and Ornithine on the activities of Ornithine carbamoyl transferase,Arginase and Aspertate Carbamoyl transferase in ammonia intoxication . Medical journal of Western India 1992 .vol.20 .pp

.

4.S.A.Abhang, P.M.Bulakh .Urea cycle and Pyrimidine synthesis in liver necrosis. Medical journal of Western India 1993 .vol.21.pp.

5.S.S.Sohoni,S.A.Abhang, MChaudhari, P.M.Bulakh Arginase as a prognostic marker during chemotherapy.Medical journal of Western India 1999 .vol.27,.pp.100.

6.S.Abhang. Arginine-a versatile molecule(Review article). Medical Journal of Western India,2011; 39(1):18-25.

7.Geeta M Bhatia SubodhiniAbhang. Oxidative stress and antioxidant status in Senile and diabetic cataract patients. The Antiseptic Feb.2013;vol 110.no2 ; page 84-87.

International Publications :

1.P.D.Masalkar, S.A.Abhang. Oxidative stress and antioxidant status in patients withalcoholic liver disease. Clinica ChemicaActa, 2005; 355;:61-5.

2CharushilaY.Kadam,Subodhini A .Abhang. Evaluation of serum levels of reduced glutathione, Glutathione –s-transferase and nitric oxide in breast cancer patients undergoing adjuvant chemotherapy. Int J.Cur.Res.Rev. july 2013;vol 05 (13) page 51.

3.ShindeAtul,Subodhini A .Abhang.Comparative study of oxidant & antioxidants in benign & malignant breast tumors- A pilot study. IntJ.Cur.Res.Rev. sept. 2013;vol 05 (18) page 37

4.Rajni Rajendra Shivkar,Subodhini Anant Abhang . Ratio of Serum Asymmetric Dimethyl Arginine (ADMA) / Nitric oxide in coronary artery disease patients. Journal of clinical and diagnostic Research. Aug.2014;.vol.8(8): CC04-CC06 .

5.Mulgund SR, Abhang SA. Evaluation Of Arginase and nitric oxide levels in sepsis. International Journal of Medical Research and Review.July-Aug.2014;.vol 2 (4)

6.Rupali Pawar, Subodhini A Abhang, et al . Study of oxidative / nitrosative stress, non-enzymatic antioxidants and markers of airflow obstruction ( FEV1%predicted ) in chronic obstructive pulmonary disease (COPD) patients. International J.Bioassay2014 ; 3(6),3092-3100.

7.RupaliPawar, Subodhini A Abhang, et al. Study of pulmonary function test with the markers of oxidative stress and nonenzymatic antioxidants in chronic obstructive pulmonary disease (COPD) patients. British Journal of Medicine & medical Research . 2014; 4(28): 4710-4722.

8.CharushilaYuvraj Kadam. Subodhini.AAbhang.Serum levels of soluble Fas ligand, Granzyme B and cytochrome C during adjuvant chemotherapy of breast cancer. Clinica Chimica acta.2015;vol.438 page98-102.

9.CY Charusheela, SA Abhang NO/cyt c ratio as a possible marker of efficacy of adjuvant chemotherapy in breast cancer . A preliminary report.European Journal of cancer . 2015 ;51, e11.

10.Kadam Charusheela Y and Abhang Subodhini A. Evaluation of serum antioxidants during adjuvant chemotherapy of breast cancer . A perspective observational study. Biochemistry & Analytical Biochemistry.2015;4(2):2-6.

11.Rupali Pawar, Subodhini A AbhangEvaluation of serum level of Neutrophil Elastase, superoxide dismutase and Nitric oxide in COPD patients and its correlation with lung function test.International Journal of Biochemistry Research &Review 2015;5(2): 153-161.

12.C.G.Yerawar, S.A.Abhang and P.N.Joshi. Arginase activity as a useful cardiac marker for differential diagnosis of UA and MI : A pilot study.International Journal of Biochemistry Research & Review 2015;5(1)82-86 .

13. Charushila Y. Kadam, Subodhini A. Abhang. Correlation of serum levels of reduced glutathione and glutathione dependent enzymes with cytochrome c after 1st cycle of adjuvant chemotherapy in breast cancer. Research Journal of Recent Sciences, 2015;4(2):55-60

14.Ms,Shelgikar Prachi, Abhang Subodhini; Iyer CM . Evaluation of Nitric Oxide levels and arginase activity in oral cancer patients. Int J.Cur.Res.Rev. 2016 ;vol 8 (11):34-37.

15.Shruti R Mulgund, Subodhini A Abhang . Correlation of Microalbumin and C-reactive protein as markers of sepsis. Int J.Cur.Res.Rev.2016;8(12):21-24.

16.N. Pendharkar A.Gajbhiye Subodhini Abhang et al. Quantitative tissue proteomic investigation of invasive ductal carcinoma of breast with luminal B hER2 enriched subtypes towards potential diagnostic and therapeutic biomarkers. Journal of proteomics.2016; 132:112-130.

17.C.Y.Kadam S .A .Abhang Apoptosis markers in Breast Cancer therapy. Advances in clinical chemistry.2016 ; 74,chapter 5: 143 -193.

18.G Bhatia .AN.Sontakke, S.Abhnag. Role of oxidative stress in cataractogenesis . International Journal of Research in Medical Scinces.2017; 5(6) : 2390-2393.

19Rupali S Pawar And Subodhini A Abhnag . Study of role of surfactant Protein-D, Malonaldehyde,Protein Carbonyl and its correlation with airflow obstruction (FEV1%predicted) in patients with smoker chronic obstructive pulmonary disease (COPD). Biochemistry and Analytical Biochemistry.2017 ; 6(3) ::321.

20Geeta Bhatia, Subodhini Abhang A. N Saontakke. Significance of Aldose reductase in Diabetic cataract, Int J.Cur.Res.Rev.. 2017; 9(11) :48-52.

21Pawar R.S Abhang S A. Evaluation of Neutrophil Elastease / Alpha- 1- Antitrypsin ratio in different stages of chronic pulmonary disease (COPD) patients. International J. of Medical Research & Review.2017; 5(7) : 664-74.

22Rupali S Pawar And Subodhini A Abhnag . Consumption of GSH with the increase in oxidative stress in chronic obstructive pulmonary disease (COPD) patients. Int J.Cur.Res.Rev .2017 ; 9(6).:25-29.

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