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Dr. KOTAIAH YALAGALA

Bio Chemist, Chemtex Environmental and Industrial Hygiene Lab,

****, **** ******, **** ******, TEXAS 77642

Phone: +1-409-***-****, 409-***-****. Email: ac2ayk@r.postjobfree.com Summary: Chemist with more than 5 years of experience in water and soil extractions for high performance liquid chromatography, extraction of total petroleum hydrocarbons, and soil extraction for gas chromatography–mass spectrometry. Also experienced in small scale laboratory management, chemical inventory management, risk management, compliance, and developing safety programs tailored to small business/research laboratory needs. Encourage teamwork and a team-player mentality to accomplish goals. Lead by example with a positive attitude and strong work ethic. Expertise in:

Responsible for the planning, organizing, and directing of laboratory tests performed on specific products and components.

Experienced in developing gas chromatography methods for petroleum, Soil and water applications by EPA methods such as EPA 8260B, EPA 8270D, EPA 625, EPA 525.2, EPA 548, EPA 524.2, ASTM D-1946, EPA M-18, TO-14A, TO-15 and many more EPA methods for the analysis various kinds matrix and petroleum products.

Expertise in provide troubleshooting support for manufacturing issues

Hands on experience in develop broad analytical skills to solve problems in analysis.

Review and update laboratory Standard Operating Procedures as needed.

Provide support and assistance to laboratory equipment issues and repairs.

Participate in all routine and special problem analysis for production units.

Sound knowledge in the analysis of various kinds of petroleum products and Industrial Hygiene samples on GC-MS, GC -PFPD & GC-FID.

Synthesis, purification and characterization (HPLC, HRMS, GC/MS, LC/MS, FTIR and 1D & 2D NMR).

Coordinate the ordering, inventory, storage, and maintenance of supplies, lab ware, and instruments essential to the operation of the lab.

Experienced in the LIMS.

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Education:

Post Doctoral Fellow in Organic Catalysis from University of Kwazulu Natal, Durban, South Africa 2014-2015.

Ph. D., Organic Chemistry, Sri Venkateswara University, Tirupati, India, 2014 Thesis Title: “Synthesis, Biological studies of novel heterocyclic compounds and Development of synthetic methodologies”.

M.Sc., in Chemistry, Sri Venkateswara University, Tirupati, India, 2008

B.Sc., Chemistry and Biology, Acharya Nagarjuna University, Guntur, India, 2006 Professional Experience:

Working as a Bio-Chemist in Chemtex Environmental Laboratory since February 2016. Research and experiment with new and innovative materials and processing techniques. Prioritize to ensure timely submissions in a fast paced environment. Supervise and offer guidance to junior chemists and technicians.

2009-2011: R&D Chemist, Drug Discovery Labs, Laila Nutraceuticals, Jawahar Autonagar, Vijayawada, Andhra Pradesh, India. Various reagents were handled such as n-Butyl bromide, LDA, sodium cyanide, selenium dioxide, POCl3, Boron tribromide, thionyl chloride, NBS, DMF-DMA, TEOF, Bromine and AlCl3. Extensive experience in the handling of various reducing agents such as NaBH4, Pd/C, Raney Nickel, LAH, Glyoxalic Acid, Hydragene Hydrate. etc., Citations

More than 150 citations in national and international journals List of Publications

1. Kotaiah, Y., Jonnalagadda, S.B., Suresh, M., Rana, S., and Suryanarayana, M., S. Novel Chromeno[2,3-d]pyrimidines - Design, Synthesis and Antioxidant Activity, Letters in Drug Design & Discovery 14(999):1-1 November 2016, DOI: 10.2174/1570180814666161123143637.

2. Suresh, M., Naicker., K., Momin., M.I.K., Rana, S.,M., Kotaiah, Y., Moganavelli S.,Neil A. K., and Jonnalagadda, S.B., Novel 2-(1-(substitutedbenzyl)-1H-tetrazol-5-yl)-3- phenylacrylonitrile derivatives: Synthesis, in vitro antitumor activity and computational studies, Medicinal Chemistry Research, 2016, 25(2) 283-291. 3. Suresh, M., Jonnalagadda, S.B., Naicker., K., Gorle, S., Rana, S., ., Kotaiah, Y., Suryanarayana, M., Moganavelli S., and Parvesh, S., New Pyrano[2,3-d:6,5- d']dipyrimidine Derivatives - Synthesis, in vitro Cytotoxicity Activity and Computational Studies, Anti-cancer agents in medicinal chemistry, 2016, 16(8) 1031-1037. 3

4. Kotaiah, Y.,Suresh, M., Rana, S., Suryanarayana, M., S., and Jonnalagadda, S.B., Synthesis, antimicrobial activity and molecular docking studies of pyrano[2,3- d]pyrimidine formimidate derivatives, Research on Chemical Intermediates, 2016, 42, 3763-3774.

5. Rana, S., Suresh, M., Kotaiah, Y., and Jonnalagadda, S.B., Organo functionalized graphene with Pd nanoparticles and its excellent catalytic activity for Suzuki coupling reaction, Applied Catalysis A: General, 2015, 505, 539-547. 6. Rana, S., Suresh, M., Kotaiah, Y., Suryanarayana, M. and Jonnalagadda, S.B., Covalent Modification of Organo-Functionalized Graphene Oxide and its Scope as Catalyst for One-Pot Pyrazolo-Pyranopyrimidine Derivatives, Chemistry Open, 2015, 4, 703-707. 7. Suresh, M., Jignesh, V., Harinarayana, B., Kotaiah, Y., Lavanya, P., Ag loaded on SiO 2 as an Efficient and Recyclable Heterogeneous Catalyst for the Synthesis of Chloro-8- substituted-9 H -purines, J. Heterocyclic Chemistry, 2016, 53 (1) 319-324. 8. Kotaiah, Y., Nagaraju, K., Harikrishna, N. and Venkata Rao, C., Yamini, L, and Vijjulatha, M., Synthesis, docking and evaluation of antioxidant and antimicrobial activities of novel 1,2,4-triazolo[3,4-b][1,3,4]thiadiazol-6-yl)selenopheno[2,3- d]pyrimidines, Euro. J. Med.Chem., 2014, 75, 95-202. 9. Kotaiah, Y., Harikrishna, N., Nagaraju, K. and Venkata Rao, C., Synthesis and antioxidant activity of 1,3,4-oxadiazole tagged thieno[2,3-d]pyrimidine derivatives, Euro. J. Med. Chem., 2012, 58, 340-345.

10. Kotaiah, Y., and Venkata Rao, C., Design, synthesis and biological evolution of 3, 4- Dihydroselenopheno [2,3-d]pyrimidine sulfonamides As potential antimicrobial agents, Int. J. Pharm Bio Sci., 2013, 4, 912 – 922.

11. Kotaiah, Y., Harikrishna, N., Nagaraju, K., Sai Gopal, D. V. R., Taranath, V. and C.Venkata Rao, C. Synthesis and antiviral activity of 1,3,4-oxadiazolyl selenopheno[2,3- d]pyrimidines as novel Bluetongue virus inhibitors, J. Chemical and Pharmaceutical Research, 2013, 5, 359-369.

12. V.Tharanath, K. Peddanna, Y. Kotaiah, D.V.R . Sai GOPAL Flavonoids Isolated from Foeniculum vulgare (Fennel) have Virostatic Efficiency Against Bluetongue Virus, International Journal of Pharmaceutical Sciences Review and Research 2013 23, 237-242. 13. Kotaiah, Y., Harikrishna, N., Nagaraju, K., Venkata Rao, C., Jonnalagadda, S. B. and Suresh M. Synthesis and Biological Evaluation of Novel Isopropyl 2-thiazolopyrimidine- 6-carboxylate Derivatives, Journal of the Korean Chemical Society, 2012, 56, 68-73. 14. Nagaraju, K., Kotaiah, Y. Sampath, C., Harikrishna, N., and Venkata Rao, C., A facile synthesis of some novel fused [1,2,4]triazolo[3,4-b][1,3,4]thiadiazol derivatives, Journal of Sulfur Chemistry, 2013, 34, 264-275.

15. Lavanya, P., Suresh, M., Kotaiah, Y., Harikrishna N. and C. Venkata rao, Synthesis, Antibacterial, Antifungal and Antioxidant Activity Studies On 6-Bromo-2- Substitutedphenyl-1h-Imidazo [4, 5-B] Pyridine, Asian Journal of Pharmaceutical and Clinical Research, 2011,4, 69-73.

16. Sampath, C., Kotaiah, Y Harikrishna, N., Nagaraju, C., Anjaneyulu, E. and Venkata Rao, C., A facile synthesis, spectral characterization and antimicrobial activity of novel dialkylheteroaryl phosphonates, Der Pharmacia Sinica, 2012, 3, 494-500. 17. Sampath, C., Harikrishna, N., Kotaiah, Y., Nagaraju, C., Balaji, M., and Venkata Rao, C., Synthesis, Spectral Characterization and Bio-activity of Novel Iminophosphorane derivatives of piperazine via Staudinger reaction, Der Pharma Chemica, 2012, 4, 288- 296.

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References:

1. Mr. Annapreddy C,

QA/QC Manager,

Chemtex, Port Arthur, TX 77642

2. Mr Ashok,

QC Chemist,

Indorama Olefins,

Sulphur, LA.

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