I am Dr. Balaji Mundhe having 13 Yrs experience In anralytical researc
Resume:
RESUME
Dr.BALAJI CHINTAMAN MUNDHE
Permanent Address:
At Post Govindpur, Tehsil Kallam, Dist-Osmanabad-413507
Personal Details:
Date of Birth:25th June 1979
Gender: Male
Marital status: Married
Languages known: English, Hindi, Marathi
Contact no. : 816-***-****
E-mail Address:********@*****.***
Objective:
To make a bright career in Academics as well as in research hand shape it with positive and bigger
outlook. Always have a boundless vision, tackle the challenges with vigorous thinking,
imagination and curiosity and bring ideas into practical reality by positive work attitude. Equip
hard work with smartness to increase efficiency, output and set levels and standards that really
exceed expectations
EDUCATIONAL QUALIFICATIONS
Sr.No.
Course
Year
of Passing
School/College/
Department/
University/Board
Marks
&
Percentage
Remark/
Class
1
Ph.D.
Chemistry
2016
Department of Chemistry,
University of Mumbai,
Vidyanagari Santacruz (E)
Mumbai 400098
--
Completed.
2
M.Sc.
Organic
Chemistry
2002
Dr.B.A.M.University
Aurangabad 431004
57.91%
IInd(B+)
3
B.Sc.
Chemistry
1999
Dr.B.A.M.University
Aurangabad 431004
63.48%
Ist
Ph.D. thesis entitled “PHYSICOCHEMICAL AND CHROMATOGRAPHIC STUDY ON SOME ANTICANCER DRUGS” from University of Mumbai in 2016.
Experience:
Total industrial experience 14 years
Sr.No.
Name of organization
Position
Department
From
To
1
Macleods Pharmaceuticals Ltd., Mumbai
Jr. Research Scientist
Analytical research and development
Sep’2007
Till date
2
Glenmark pharmaceuticals Ltd, Mohol,Dist. Solapur.
Q C. Officer
Quality control
Sep’2004
Aug’2007
3
Harman Finochem Ltd., Aurangabad
Q.C/Q.A Chemist
Quality control/ Quality Assurance
Mar’2004
Aug’2004
4
Innotech Pharma Ltd, Aurangabad
Q.C/Q.A Chemist
Quality control/ Quality Assurance
Mar’2003
Feb’2004
AREA EXPERTISE:
Adept at supervising analytical work & documentation as per pharmaceutical industry regulations & various other regulatory authorities.
Search, reading and interpretation the literature on the assigned project.
Participation in the technical discussion on the product development.
Planning and conducting the experiments.
Assisting the compilation of development report.
Assisting the plant personnel in the execution of audits [regulatory and semi regulatory authorities].
Demonstrated prowess in handling Calibration of instruments & maintaining records as per calibration plan
Well versed with the Analytical method development & Validation of API, & formulated finished products, like Tablet, Capsule and Oral syrup.
Expertise in handling QA activities pertaining to PDS, Checking & Report Checking and Auditing.
Dexterously handled various laboratory deviations; keenly handled out of specification & out of trends.
Hands on experience in the field of Quality Systems, Regulatory Affairs, Instruments and Quality Control.
A keen communicator with honed problem solving and analytical abilities with an in depth experience of handling both domestic and regularity market.
Possess in depth experience in Method Development Assay of :
oRelated substances and dissolution for Formulated finished products,
oRelated substances and Enantiomeric Purity for API.
Deft in handling:
oCalibration of instruments & their records as per Calibration plan.
oConducting Stability study as per ICH guideline
oConducting Routine analysis of API and Formulated developed of products
oMaintaining laboratory records as per cGLP
Proficient in:
oPreparing various primary standards & working standards.
oMaintaining various records of Raw material, intermediate & finished product for future reference.
Preparing Standard of Procedure and making revision of Raw material, intermediate & finished product specification & initiating change control.
Analytical Research
Managing development of analytical methods for pharmaceuticals preparations.
Validating analytical methods on basis of specificity, linearity, accuracy, precision, range, detection & quantization limit, and robustness as per ICH guidelines.
Ascertaining smooth technology transfer of new / re-qualified methods into regular use and into the stability program.
Regulatory Affairs
Preparing specification SOPs & relevant documents as well as undertaking training of regulatory personnel.
Supervising the analytical work & documentation as per the biotechnological regulations and various regulatory authorities.
Devising the system of regulatory query response which not only ensures effective document archival and retrieval, but also cuts the turn-around time to less than a week.
Highlights across tenure:
Successfully audit facing like USFDA, WHO, Customer and FDA audits, Harman Finochem Ltd., Glenmark Pharma Ltd and Macleods Pharma Ltd. etc.
Instrument handling:
Adept in handling various instruments like :
HPLC, Agilent
RID, PDA& UV Detector
Chemstation software
Shimadzu-LC2010AHT
LC-2010CHT UV Detector .LC
Solution & Class VP software, WATER Alliance
GC:
Shimadzu 14 B Class GC software
Head Space GC- PERKIN Elmer CLARUS TCN Software. FT/IR- Perkin
Elmer Spetrumeone Software.
UV/VIS, Spectrophotometer:
Perkin Elmer
Shimadzu
OTHER INSTRUMENTS:
Digital Polarimeter
Infrared Spectrophotometer -Perkin Elmer
KF-Autotitrator pH meter
Potentiometer Autotitrator
Conductivity Meter
Dissolution Apparatus
Disintegration Apparatus
TLC & Other methods of Wetchemical analysis.
Computer skill:
Well versed with MS-DOS
Microsoft office.
SAP (QM Module, 4.7 Version) and Internet Application
Access Knowledge of Origin, ChemDraw, ISIS Draw and ChemSketchSoftwares
Access Knowledge of Scifinder, Chemical Abstract Services.
ORAL AND POSTER PRESENTED AT CONFERENCES:
1] Oral Presentation on “Spectroscopic Investigation of Binding of Nevirapine with Bovine Serum Albumin” at “International Symposium in New Horizons in Chemistry”
(ISNHC-2014) organized by Department of Chemistry, Vivekanand Education Society’s College of Arts, Science and Commerce on 08th -09th December 2014.
M.M.V.Ramana, Prasanna B. Ranade, Rahul R. Betkar, Amey P. Nimkar, Balaji C. Mundhe. (First Rank)
2] Presented a poster entitled “Synthesis of substituted thiazolo [2, 3-a] isoquinolines”
At National Symposium on “Emerging Trends in Chirality, Medicinal Chemistry and Perfumery (ETCMP 2015)” at V. G. Vaze College, Mulund (E), Mumbai, on 04th February 2015.
M.M.V.Ramana, Prasanna B. Ranade, Rahul R. Betkar, Amey P. Nimkar, Balaji C. Mundhe.
3] Oral Presentation on “A process for synthesis and spectroscopic investigation of binding of 10b cyclobutyl-5, 6-dihydro-2H-thiazolo [2, 3-a] isoquinolin-3(10bH)-one with Bovine Serum Albumin.” at UGC-SAP Sponsored “National Conference on Advances and Innovations in Chemical Sciences”(NCAICS-2015) at Department of Chemistry, University of Mumbai on 12th -13th February 2015.
M.M.V.Ramana, Prasanna B. Ranade, Rahul R. Betkar, Amey P. Nimkar, Balaji C. Mundhe.
4] Presented a poster entitled “One pot synthesis of 2-amino-4, 6-diaryl pyrimidines using Cesium hydroxide-Alumina” at “International Symposium in New Horizons in Chemistry” (ISNHC-2014) organized by Department of Chemistry, Vivekanand Education Society’s College of Arts, Science and Commerce on 08th -09th December 2014.
M.M.V.Ramana, Amey P. Nimkar, Rahul R. Betkar, Prasanna B. Ranade, Balaji C. Mundhe.
PATENTS FILED TO INDIAN PATENT OFFICE:
1] “In vitro study on the binding of streptozocin to bovine serum albumin.” 2532/MUM/2015
M. M. V. Ramana*, Balaji Mundhe, Rahul Betkar, Amey Nimkar, Prasanna Ranade
2] “Rapid methods for determining binding between serum albumin and Azacitidine, an anti-cancer drug.”
2533/MUM/2015
M. M. V. Ramana*, Balaji Mundhe, Rahul Betkar, Amey Nimkar, Prasanna Ranade
3] “A process for the preparation of o-substituted Benzophenone derivatives.” 443/MUM/2014
M. M. V. Ramana*, Rahul Betkar, Amey Nimkar, Prasanna Ranade, Balaji Mundhe
4] “A process for the preparation of 6-amino-5-cyano-2-methyl-4-aryl-4H pyran-3-carboxylates.” 1486/MUM/2014
M. M. V. Ramana*, Rahul Betkar, Amey Nimkar, Prasanna Ranade, Balaji Mundhe
5] “Rapid methods for determining binding between serum albumin and nevirapine, an anti-retroviral drug.”
2681/MUM/2014, (online copy available)
M. M. V. Ramana*, Rahul Betkar, Amey Nimkar, Prasanna Ranade, Balaji Mundhe
6] “A process for synthesis of Benzopyranyl pyrimidine derivatives.” 4052/MUM/2014
M. M. V. Ramana*, Prasanna B. Ranade, Rahul R. Betkar, Amey Nimkar, Balaji C. Mundhe.
7] “A process for the synthesis of 10b-aryl substituted thiazolo [2, 3-a] isoquinoline derivatives.”
4213/MUM/2014
M.M.V.Ramana*, Prasanna B. Ranade, Rahul R. Betkar, Amey Nimkar, Balaji C. Mundhe.
8] “The process for the synthesis of 10B alkyl substituted thiazolo [2, 3-a] isoquinolene derivatives”
413/MUM/2015
M. M. V. Ramana*, Prasanna Ranade, Rahul Betkar, Amey Nimkar, Balaji Mundhe
9] “A process for the synthesis and spectroscopic investigation of binding of 10B cyclobutyl-5, 6- dihydro 2H thiazolo[2,3A]-isoquinolene-3-(10H)-1-one with BSA” 414/MUM/2015.
M. M. V. Ramana*, Prasanna Ranade, Rahul Betkar, Amey Nimkar, Balaji Mundhe
10] “In vitro methods for determining alteration of bovine serum albumin environment upon interacting with 2-amino-4-(3-chlorophenyl)-4H-benzo[h] chromene-3-carbonitrile” 948/MUM/2015
M. M. V. Ramana*, Amey Nimkar, Rahul Betkar, Prasanna Ranade, Balaji Mundhe
11] “A process for the synthesis and spectroscopic investigation of binding of 13A-(thiophene-2-yl)-5,6-dihydrobenzo[5, 6]oxazino[2, 3A] isoquinole-3-(10H)-1-one with BSA”
1011/MUM/2015.
M. M. V. Ramana*, Prasanna Ranade, Rahul Betkar, Amey Nimkar, Balaji Mundhe
12] “Spectroscopic methods for determining interaction of 3-amino-1-(3-fluorophenyl)-1H-benzo[f]chromene-2-carbonitrile with bovine serum albumin.” 1395/MUM/2015
M. M. V. Ramana*, Amey Nimkar, Rahul Betkar, Prasanna Ranade, Balaji Mundhe
13] “Biophysical methods to determine the mode of binding of streptozotocin to HS DNA” 3731/MUM/2015
M. M. V. Ramana*, Balaji Mundhe, Rahul Betkar, Amey Nimkar, Prasanna Ranade.
LIST OF PUBLICATIONS:
1] “Natural and virtually designed flavonoids: Potential anti-HCV targets in silico approach.”
M. M. V. Ramana*, Amey Nimkar, Rahul R. Betkar, Prasanna B. Ranade, Balaji Mundhe.
J. Chem. Pharm. Res., 2015, 7, 82.
2] “In vitro DNA binding studies of antiretroviral drug nelfinavir using ethidium bromide as fluorescence probe.”
M. M. V. Ramana*, Rahul R. Betkar, Amey Nimkar, Prasanna B. Ranade, Balaji Mundhe.
J. Photochem. Photobio B: Biology, 2015, 151,194.
3] “Synthesis of a novel 4H-pyran analog as minor groove binder to DNA using ethidium bromide as fluorescence probe.”
M. M. V. Ramana*, Rahul R. Betkar, Amey Nimkar, Prasanna B. Ranade, Balaji Mundhe, Sachin Pardeshi.
Spectrochim.Acta, Part A, 2015, 152, 165.
4] “Green synthesis of thiazolo [2, 3-a] isoquinolines using silica sulphuric acid under microwave irradiation”
M. M. V. Ramana*, Prasanna B. Ranade, Rahul R. Betkar, Amey Nimkar, Balaji Mundhe.
Heterocycl.Lett.,2015, 5, 451.
5]CsOH/ γ-Al2O3 Catalyzed mild and efficient method for the synthesis of novel multifunctionaliszed 4H-Pyran derivatives via one pot three component protocol Heterocyclic Letters 2015,5,1, 85-95
M.M.V. Ramana, Rahul Betkar, Amey Nimkar, Prasanna Ranade, Balaji Mundhe
6] KF-Al2O3 Mediated Microwave Assisted One Pot Synthesis of Benzopyranyl pyrimidines.
World Journal of Pharmaceutical Research 2015, 4, 7, 1510-1516.
M. M. V. Ramana, Prasanna B. Ranade, Rahul R. Betkar, Amey P. Nimkar, Balaji C. Mundhe.
7]Chalcones: Potential antidengue targets in silico approach. Journal of Computational Methods in Molecular Design 2015, 5, 3, 104-105.
M.M.V.Ramana, Prasanna B. Ranade, Rahul R. Betkar, Amey P. Nimkar, Balaji C. Mundhe and Shanta Bhar.
8] Flavones: Potential antidengue targets in silico approach Journal of Chemical and Pharmaceutical Research 2015, 7, 8, 585-591.
M.M.V.Ramana, Prasanna B. Ranade, Rahul R. Betkar, Amey P. Nimkar, Balaji C. Mundhe and Shanta Bhar.
9] Flavanones: Potential antidengue targets in silico approach. Journal of Chemical and Pharmaceutical Research 2015, 7, 9, 469-474.
M.M.V.Ramana, Prasanna B. Ranade, Rahul R. Betkar, Amey P. Nimkar, Balaji C. Mundhe and Shanta Bhar.
DECLARATION:
I hereby declare that the above written particulars are true to the best of my knowledge and belief.
Dr. BALAJI C. MUNDHE.
Contact this candidate