PROFESSIONAL EXPERIENCE
Infotree Services Inc., Pittsburgh, PA, October 2016 - February 2017
Clinical Data Associate (contract)
Build, test, and analyze health databases in Excel, Access, Datatrak, and SAS
Coordinate clinical patient registry updates and emails
Self-employed, Pittsburgh, PA, August 2015 - October 2016
Clinical and Epidemiological Research Consultant
Assist investigators with all aspects of their research projects including, writing grant proposals, setup data analysis plans and databases, and write, edit and analyze clinical research data using Excel and SAS.
Stay current with regulatory policies and clinical research literature for diseases.
Oxford Solutions for ERT, Pittsburgh, PA, April 2015 – August 2015
Solution Design Specialist (contract)
Coordinate overall Solutions Design process ensuring that clinical protocols are appropriately mapped to software solutions efficiently, accurately and within project scope and serve as the therapeutic subject matter expert in the Design/Build phase of assigned projects
Community College of Allegheny County, Pittsburgh, PA, August 2014 – November 2014
Adjunct Faculty in Biological Sciences
Teach non-major Life Science, General Biology, Anatomy and Physiology, and Genetics
Design syllabus and assessment requirements as well as conduct laboratory exercises
Mentor and tutor students
UPMC Stroke Institute, University of Pittsburgh, Pittsburgh, PA, January 2008 – June 2014
Clinical Research Coordinator (Health Professional II)
Manage novel and proof of concept clinical research studies involving acute stroke patients
Recruit patients, collect data and assist investigators during patient enrollment and consenting
Schedule and conduct research patient follow-up visits
Educate research team through in-service presentations as needed
Abstract and enter data into study database
Database management with SAS and Excel
Prepare budgets and fiscal review/tracking
Submit applications to institutional review boards
Work closely with industry/academic sponsors and study research monitors
Oversee quality initiative projects
Assist with abstract and manuscript statistics and writing
Participate in community education and outreach via health fairs
Participate in the American Heart Association Heart Walk as team captain
Children’s Hospital of Pittsburgh, Pittsburgh, PA, August 2007 – January 2008
Research Technician II
Recruit patients for brain injury research study
Database management with Microsoft excel
Prepare manuscripts, abstracts and IRB protocols
Supervise student workers
Community College of Allegheny County, Pittsburgh, PA, May 2006 – December 2007
Adjunct Faculty in Biological Sciences – (see above)
University of Pittsburgh, Pittsburgh, PA, August 2003 – August 2007
Graduate Student Researcher
Studied genetics of osteoporosis in men of Afro-Caribbean descent
Managed and analyzed epidemiological and genetic data with SAS (statistical software)
Wrote abstracts and manuscripts, presented results at scientific meetings
Lab assays include DNA isolation, genotyping and SNP (Single Nucleotide Polymorphisms) analysis
University of Pittsburgh, Pittsburgh, PA, August 2001 – August 2003
Research Specialist
Studied role of cytokines in normal bone turnover and osteoporosis
Cell culture and manipulation - monocyte isolation, various cell lines - hMSC’s, fibroblasts
Microscopy and FACS (flow cytometry) analysis
PCR and transfection
Magee Women’s Research Institute, Pittsburgh, PA, August 2000 – August 2001
Research Technician
TGF-b signal transduction in ovarian physiology
HPLC sample prep and lipid enzyme analysis
Western blot, Northern blot and PCR
Primary cell culture from Sprague-Dawley rats
University of Kentucky, Lexington, KY, February 1999 – August 2000
Research Technician
Studied role of ceramides in aging with HPLC sample prep
Lipid enzyme analysis
Western blot, Northern blot and PCR.
Primary cell culture (rat and human)
Department of Biochemistry, Oklahoma University, Norman, OK, 1998
Research and DNA Sequencing Technician – Human Genome Project
DNA sequencing, media preparation, and “Competent cell” culture
Martek Biosciences, Winchester, KY, 1997
Laboratory Technician
Maintained algal starter cultures and inoculated fermenters for large scale culturing
Screened cultures for bacterial contamination and QA/QC assays of final algal oil product
EDUCATION
University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA
Master of Public Health (MPH) in Epidemiology, 2014
California University of Pennsylvania, California, PA
Bachelor of Science (BS) in Biological Sciences, 1994
MANUSCRIPTS PUBLISHED
Derdeyn CP, Chimowitz MI, Lynn MJ, Fiorella D, Turan TN, Janis LS, Montgomery J, Nizam A, Lane BF, Lutsep HL, Barnwell SL, Waters MF, Hoh BL, Hourihane JM, Levy EI, Alexandrov AV, Harrigan MR, Chiu D, Klucznik RP, Clark JM, McDougall CG, Johnson MD, Pride GL Jr, Lynch JR, Zaidat OO, Rumboldt Z, Cloft HJ; Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis Trial Investigators. Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial. Lancet. 2014 Jan 25; 383(9914): 333-41.
Ribo M, Molina CA, Jankowitz B, Tomasello A, Zaidi S, Jumaa M, Coscojuela P, Oakley J, Alvarez-Sabín J, Jovin T.J. Stentrievers versus other endovascular treatment methods for acute stroke: comparison of procedural results and their relationship to outcomes. Neurointerv Surg. 2014 May; 6(4): 265-9.
Kidwell CS, Jahan R, Gornbein J, Alger JR, Nenov V, Ajani Z, Feng L, Meyer BC, Olson S, Schwamm LH, Yoo AJ, Marshall RS, Meyers PM, Yavagal DR, Wintermark M, Guzy J, Starkman S, Saver JL; MR RESCUE Investigators. A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med. 2013 Mar 7;368(10):914-23.
Chimowitz MI, Lynn MJ, Derdeyn CP, Turan TN, Fiorella D, Lane BF, Janis LS, Lutsep HL, Barnwell SL, Waters MF, Hoh BL, Hourihane JM, Levy EI, Alexandrov AV, Harrigan MR, Chiu D, Klucznik RP, Clark JM, McDougall CG, Johnson MD, Pride GL Jr, Torbey MT, Zaidat OO, Rumboldt Z, Cloft HJ; SAMMPRIS Trial Investigators. Stenting versus aggressive medical therapy for intracranial arterial stenosis. N Engl J Med. 2011 Sep 15;365(11):993-1003.
Chimowitz MI, Lynn MJ, Turan TN, Fiorella D, Lane BF, Janis S, Derdeyn CP; SAMMPRIS Investigators. Design of the stenting and aggressive medical management for preventing recurrent stroke in intracranial stenosis trial. J Stroke Cerebrovasc Dis. 2011 Jul-Aug;20(4):357-68.
Jumaa MA, Zhang F, Ruiz-Ares G, Gelzinis T, Malik AM, Aleu A, Oakley JI, Jankowitz B, Lin R, Reddy V, Zaidi SF, Hammer M, Wechsler LR, Horowitz M, Jovin TG. Comparison of Safety and Clinical and Radiographic Outcomes in Endovascular Acute Stroke Therapy for proximal middle cerebral artery occlusion with intubation and General Anesthesia versus the non-intubated state. Stroke, 2010 Jun;41(6):1180-4. PMID: 20431082
Moffett SP*, Oakley JI*, Cauley JA, Li-Yung Lui, Ensrud KE, Taylor B, Hillier TA, Hochberg MC, Li J, Cayabyab S, Lee JM, Peltz G, Cummings SR, Zmuda JM, for the SOF Research Group. Osteoprotegerin Lys3Asn Polymorphism and the Risk of Fracture in Older Women. J Clin Endocrinol Metab. 2008 May;93(5):2002-8. Epub 2008 Mar 4. (*co-1st author)
Moffett SP, Zmuda JM, Oakley JI, Beck TJ, Cauley JA, Stone KL, Lui LY, Ensrud KE, Hillier TA, Hochberg MC, Morin P, Peltz G, Greene D, Cummings SR. Tumor Necrosis Factor Alpha Polymorphism, Bone Strength Phenotypes, and the Risk of Fracture in Older Women. J Clin Endocrinol Metab. 2005 Jun;90(6):3491-7. Epub 2005 Mar 29.
Blair HC, Borysenko CW, Villa A, Schlesinger PH, Kalla SE, Yaroslavskiy BB, Garcia-Palacios V, Oakley JI, Orchard PJ. In vitro differentiation of CD14 cells from osteopetrotic subjects: contrasting phenotypes with TCIRG1, CLCN7, and attachment defects. J Bone Miner Res. 2004 Aug;19(8):1329-38
Yaroslavskiy BB, Li Y, Ferguson DJ, Kalla SE, Oakley JI, Blair HC. Autocrine and paracrine nitric oxide regulate attachment of human osteoclasts. J Cell Biochem. 2004 Apr 1;91(5):962-72
Cao L, Bu R, Oakley JI, Kalla SE, Blair HC. Estrogen receptor-beta modulates synthesis
of bone matrix proteins in human osteoblast-like MG63 cells. J Cell Biochem. 2003
May 1;89(1):152-64.
Xu J, Oakley J, McGee EA. Stage-specific expression of Smad2 and Smad3 during
folliculogenesis. Biol Reprod. 2002 Jun:66(6):1571-8. PMID 12021033
Lightle SA, Oakley JI, Nikolova-Karakashian MN. Activation of sphingolipid turnover
and chronic generation of ceramide and sphingosine in liver during aging. Mech Ageing
Dev. 2000 Dec 1;120(1-3):111-25.
ABSTRACTS
Marc Ribo, Brian Jankowitz, Syed Zaidi, Mouhammad Jumaa, Jennifer Oakley, and Tudor Jovin. Delayed Device Access to the Occluded Target Vessel Predicts Worse Recanalization Rates and Poor Outcomes in Endovascular Therapy for Acute Stroke. Stroke. 2013;44:AWMP6
Guillermo Linares, Kees H Polderman, Lawrence R Wechsler, Santiago Ortega-Gutierrez, Brian Jankowitz, Michael B Horowitz, Vivek Reddy, Maxim D Hammer, Ashutosh P Jadhav, Ramesh Grandhi, Jennifer Oakley, Steven A Koehler, and Tudor G Jovin. Simultaneous Endovenous Hypothermia and Intra-Arterial Thrombectomy for Acute Ischemic Stroke is Safe, Feasible and Does Not Require General Anesthesia. Stroke. 2013;44:ATP14
Decreases in Lean Mass are Strongly Associated with the Rate of Loss in Hip Bone Mineral Density with Aging among Afro-Caribbean Men. Sheu Y, Cauley JA, Wheeler VW, Bunker CH, Patrick AL, Oakley JI, Zmuda JM. 28th ASBMR Annual Meeting, September 2006.
Osteoprotegerin Promoter Polymorphism, Bone Density and the Risk of Hip Fracture in Older Women. Oakley JI, Zmuda JM, Moffett SP, Stone KL, Lui LY, Li J, Cauley JA, Taylor BC, Hillier TA, Browner W, Hochberg MC, Peltz G, Cummings SR. (Oral presentation) 27th ASBMR Annual Meeting, September 2005.
Characterization of genomic variation at the Wnt10b Locus: Novel Association of Wnt10b genotypes with bone density in a multi-ethnic sample of older men. Oakley JI, Moffett SM, Yerges LM, Nestlerode CS, Wheeler VW, Patrick AL, Bunker CH, Zmuda JM. 27th ASBMR Annual Meeting, September 2005.
Identification and Characterization of Sequence variation at the Human Frizzled-1 (FZD1) Locus. JI Oakley, SP Moffett, CS Nestlerode, VW Wheeler, AL Patrick, CH Bunker, JM Zmuda. ASHG Meeting, October 2004.
LRP5 Amino Acid Substitutions: Ethnic Differences in Allele Frequencies and Association with Bone Density and Structure in Afro-Caribbean Men. Oakley JI, Moffett SP, Petro N, Cauley JA, Beck TJ, Bunker CH, Patrick AL, Wheeler VW, Ferrell RE, Zmuda JM. 26th ASBMR Annual Meeting, October 2004.
Nitric Oxide Regulates Human Osteoclasts via G-kinase and M-calpain Mediated Disassociation of Specific Cytoskeletal Proteins. Yaroslavskiy B, Mamoune A, Li Y,Bu R, Kalla SE, Oakley JI, Wells A, Blair HC. 25th ASMBR Annual Meeting, September 2003.
Free radical acceleration of ECM turnover: role of NADPH oxidase. SE Kalla, JI Oakley, Y Li, HC Blair. 42nd ASCB Annual Meeting MCB, December 2002 25th ASBMR Annual Meeting, September 2004
Gene silencing of NADPH oxidase dramatically reduces osteoclast pit formation, reproducing mild osteopetrosis. SE Kalla, PJ Orchard, Y Li, JI Oakley, PH Schlesinger, HC Blair. 24th ASMBR Annual Meeting, September 2002
Molecular characterization of osteopetrosis (OP) using nonadherent CD14 peripheral monocytes expanded in vitro. PJ Orchard, PH Schlesinger, R Bu, SE Kalla, JI Oakley, HC Blair. 24th ASBMR Annual Meeting, September 2002
Nitric oxide regulates acid secretion bidirectionally in human osteoclasts. G Hao, YN Li, SE Kalla, JI Oakley, M Zaidi, HC Blair. 24th ASBMR Annual Meeting, September 2002
HGF and SCF support proliferation of human osteoclast precursors in vitro. HC Blair, R Bu, JI Oakley, SE Kalla. 24th ASBMR Annual Meeting, September 2002
Human monocytic colonies from peripheral blood in media containing IL-1, IL-6, and SCF, and differentiation to osteoclasts in TNF-alpha and CSF-1. R Bu, JI Oakley, OJ Bergh, SE Kalla, L Cao, HC Blair. 41st ASCB Annual Meeting MCB, December 2001
Gonadotropins upregulate the expression of SMAD3 in granulose cells from preovulatory follicles. McGee EA, Oakley J, Xu J. 56th Annual Meeting of the American Society for Reproductive Medicine. 2000
The expression of the signal transduction molecules smad2 and smad3 is reduced in preovulatory follicles and corpora lutea. Xu J, Oakley J, McGee EA. 33rd Annual Meeting of the Society for Reproduction, 2000