Shuyang (Esther) Wu
Daly City, CA 94015 ****@**.***
SUMMARY OF QUALIFICATIONS
* *****’ experience in biomedical research and data analysis
Experience in NGS analysis, predictive modeling, natural language processing, AWS etc.
Work well independently and on team projects, fast learner.
Proficient computer skills including Python, R, Java, Javascript, HTML, CSS, Git, C++, Matlab and MS office
EXPERIENCE
Bioinformatics Analyst Intern at Genentech, Oncology Biomarker Development 6/2017 – present
Analyzed RNA-seq data, Mass Spec data, Chip-Seq data and FACS data with R and Flowjo.
Pathway analysis with IPA, GSEA and Advaita
Visualized the results and drafted manuscript for publication
Research Assistant at Mark Whipple’s lab, University of Washington 10/2015 – 12/2016
Extracted and prepared gene expression profile data and cancer prognosis data of the patients using Python
Developed machine learning models for cancer metastasis including Hidden Markov Model and Bayesian Network using R
Visualized the results and developed a medical decision support application using R Shiny
Improved prediction accuracy compared to the existing model and clinicians’ current method of decision-making
Research Assistant at Annie Chen’s lab, University of Washington 12/2016 - - present
Developed machine learning and statistical models for Intellicare Apps usage pattern discovery using Python
Analyzed and extracted topics from patients’ posts from the Intellicare Apps using Python
Found associations between patients’ recovery from depression and Apps usage, topics of the posts and demographic information
Visualized the usage pattern and topics extracted from patients’ posts for clustered groups of patients with D3.js
Developed a python web application using Angular.js, Cherrypy, Jinja2, MySQL
Research Assistant at Lu Bai’s lab, Pennsylvania State University 5/2012 – 5/2015
Skills: FACS, Tissue Culture, Time-lapse microscopy, Yeast/bacteria Transformation, Immunofluorescence Microscopy, PCR/Inverse PCR/RT q-PCR, site directed mutagenesis, sequence analysis, protein expression and purification, etc.
Accomplished a project studying the expression variations of co-regulated divergent gene pairs
Investigated the potential cause of the unexpected outcomes from transposon mutagenesis
Analyzed time-lapse microscopy results for a project studying the mechanism of divergent transcription
Assisted in the project studying the position effect on gene expression in yeast genome
Provide basic technical support such as making medium, autoclave glassware, etc.
EDUCATION
University of Washington - Seattle 2015- present
Master of Science, Biomedical and Health Informatics GPA:3.74
The Pennsylvania State University 2011-2015
Bachelor of Science, Biochemistry and Molecular Biology GPA:3.90
Nutritional Science, Minor
PUBLICATIONS AND PRESENTATIONS
“A Bayesian Network Model of Head and Neck Squamous Cell Carcinoma Incorporating Gene Expression Profiles” MedInfo 2017.
“Coordinated Markov Modeling of Cancer Metastasis from Multiple Primary Sites” APAMI 2016.
“Regulation of Cell-to-Cell Variability in Divergent Gene Expression” Nature Communication.
GRANTS, HONOR AND AWARDS
Dean’s list 2011-2015
Recipient of Undergraduate Research Award from Eberly College of Science: 2013 fall, 2014 fall
Member of The Honor Society of Phi Kappa Phi as part of the top 10 percent of seniors: 2015