Quality Assurance Control

Reddy V

** ********, ***. * *****: **********@*****.***

Lowell, MA 01854 Mobile: 732-***-****

Education

New Jersey Institute of Technology – Newark, NJ, USA

Masters of Science in Pharmaceutical Chemistry SEPT 2011-Dec 2012

Jawaharlal Nehru Technological University(JNTU) – Hyderabad, AP, India

Bachelors of Pharmacy OCT 2007- May 2011

Course Work

Advanced Analytical Chemistry Computational Molecular Modeling

Medicinal chemistry Bio Chemistry Natural products

Pharmacology Organic Chemistry Instrumental Analysis

Pharmacutical Analysis Clinical Pharmacology Pharmacognosy

Microbiology Synthetic Chemistry

Technical Skills

Operating Systems: Windows (XP, 7);Linux.

Instruments: GC, HPLC, UV Spectroscopy,Mass Spectroscopy, LC/MS,Punching machine, Refractometer, Flame photometry, PHmeter, Electrophorosis, DSC, DTA, X- Ray Diffraction.

Software of Drug Design and Development: Chem sketch, Mopac, Sybyl, Alchemy.

Others:GLP, cGMP, Cell Culture, Microsoft Office, Formatting computer, assembling Computer Parts, troubleshooting.

Experience

NJIT,Academic Lab consultant Nov 2011- Dec 2012.

Maintaining Computers, Installing, Troubleshooting Softwares, Formating And Cleaning Viruses in Academic Computer Lab.

INTERNSHIP:

S M S PHARMACEUTICALS LIMITED, HYDERABAD,AP, INDIA. MAY 2010-NOV 2010

Bulk Drug Industry. Experienced with Production of Bulk drugs, all units in company Production, Quality Assurance, Quality control, Research &Development operations based on GLP, cGMP. Handled many Analytical Instruments. Experienced working in a laboratory with in such techniques as High Performance Liquid Chromatography (HPLC), Gas Chromatography and Different Analytical Equipment to Test the Drug. Learned Different Laboratory Techniques and Methods.

Academic Projects

GUIDE: Dr.V.V.S. Rajedra Prasad. Hyderabad, India: 2010-2011.

‘’SYNTHESIS AND BIOLOGICAL EVALUATION OF ACRIDONE DERIVATIVES:” As a member of the Four-person project team, I’ve synthesized three different derivatives of Acridone Using multible organic synthesis and Analysed the synthesized drugs by NMR, High performance liquid chromatography(HPLC) and Mass spectroscopy(LC/MS).

GUIDE: Dr.Joseph W Bozzelli, NJIT: May-2012

“THERMOCHEMICAL PROPERTIES FOR SERINE AND ITS CARBON-CENTERED RADICALSEDITRE-ORDER SECTION”. Density functional theory (DFT) based calculations are performed on SERINE and its radicals resulting from the loss of their skeletal hydrogen atoms. Geometries, vibration frequencies, and thermochemical properties [S (T) and C p(T) (298 K T 1500 K)] are calculated at the B3LYP/6-31G(d,p) DFT level and reported. ΔfH 298 values are from B3LYP/6-31G(d,p) levels. Molecular structures, vibration frequencies and internal rotor potentials were calculated at DFT level. The standard enthalpies of formation at 298 K were evaluated using isodesmic reaction schemes with work reactions. The enthalpy of the SERINE parent molecule has been estimated to be at -133.7kcal mol-1.

“MOLECULAR MODELLING STUDIES OF NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS AND DESINGING A NEW AGONIST”. The main objective is to design a highly potent totally rigid agonist with which to gauge the recognition site of the nicotinic receptor. The minimum essential structure that activates the nicotinic acetylcholine receptor of voluntary muscle is the tetra methyl ammonium ion. The high potency of 3b and its monocyclic structure make it an ideal model compound which was used as a template for the superimposition studies. Computer assisted molecular modeling studies helped to delineate additional factors that may contribute to potency. The factors are (1) the ground state conformation, (2) superimposability of the H-bond acceptor and the cationic head on to the template, (3) electrostatic potential at the cationic head and at the H-bond acceptor site, and (4) the presence of a methyl group bonded to the carbon atom that bears the H-bond acceptor.

“DESIGN OF NEW DRUG BASED ON ZILEUTON”.

Design of a new molecule from the basic structure i.e, Zileuton was done along with the considerations of Structural Activity Relationships of different compounds with the same enzyme. Form the observed structural activity relationships we designed a molecule which we think might show increase in activity when compared to Zileuton. We Designed New drug based on Enzyme Inhibition And effective than Zileuton.

Technical Paper Presentations

Presented a paper on “Anti Cancer Drugs” at Promethean 2010,a national level technical festival held at BVRIT (B.V Raju Institute of Technology).Presented Different Methods of Preparation of Anti cancer Drugs. In Paper Recently invented drugs, Clinical trail drugs, Effects Of drugs Presented.

Presented a paper on “Quinozoline Derivatives” in Tempus ‘11,a State level technical festival held at SIPS (Sitha Institute of Pharmaceutical Sciences). Different Synthesis Methods of Quinozoline Derivatives And Evaluation methods Presented In this Paper.

Extra Curricular Activities

Recognized as one of the best Project demonstrator in final year of my undergraduation program.

Undergraduate Tutor( Organic Chemistry, Analytical Chemistry)

Studying news about releasing drugs and Scientific development.

Learning new upcoming technologies and discussing with friends on the subject for improving knowledge.

Certified Pega System Architect(PRPCv6.2).

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