Research Associate

Joseph A. Lopez

*** ****** ******, **** ***, Cambridge, Massachusetts 02140

443-***-**** (primary phone - cell) **********@*****.***

EDUCATION

College of the Holy Cross, Worcester, Massachusetts

Bachelor of Arts, Chemistry May 2009

LABORATORY EXPERIENCE

Contractor (Randstad)- Compound Management, AstraZeneca R&D September 2012- Present

• Manage chemical library of 12,000 pharmaceuticals in the Compound Management Group (CMG)

• Weigh, receive, and ship compounds in a timely manner to fill customer orders

• Perform weekly quality control checks on liquid robotics platforms

• Utilize robotics to perform compound solubilization and dilutions for high-throughput screening

• Collaborate with researchers to determine needs in order to best assist in discovery goals

Research Technologist, Johns Hopkins School of Public Health January 2010-August 2012

• Performed cytokine and chemokine protein detection for the Multicenter AIDS Cohort Study’s (MACS) longitudinal

biomarkers study

• Coordinated shipping, organization, storage, and catalogue of 15,000 MACS serum samples

• Mastered MesoScale Discovery, a multiplex alternative to ELISA, for protein quantification

• Trained staff and students in proper use of the MSD and designed proper testing protocols

• Presented findings and answered questions during weekly Lab meetings and national MACS meetings

Research Assistant, College of the Holy Cross June 2007-May 2009

• Conducted independent research under direction of Inorganic Chemistry Professor on a Rhenium Carbonyl Polydentate

diagnostic imaging research project

• Used NMR, IR, Uv-Vis, column chromatography and x-ray crystallography to verify results and purity

• Performed multistep inorganic synthesis in aerobic and anaerobic conditions

Organic Chemistry Lab Teacher’s Assistant, College of the Holy Cross September 2006-May 2009

• Assisted lab supervisor and serve as a knowledgeable resource to students

• Prepared chemical aliquots and solutions as well as equipment, including GC-MS and HPLC, for classes

PUBLICATIONS

Cytokine, 2012, 661–666. Differential serum cytokine responses to inactivated and live attenuated seasonal influenza vaccines.

J. Antimicrobial Chemotherapy, 2012, 398-403. Novel Structurally Related Compounds Reactivate Latent HIV-1 in a BCL -2-

Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation.

J. Organomet. Chem, 2012, 160-165. Complexes formed from reactions of Re(CO)3(H2O)3+ with amines used for biological

buffering.

J. Immunological Methods, 2011, 71-77. Multiplex Measurement of Proinflammatory Cytokines in Human Serum:

Comparison of the Meso Scale Discovery Electrochemiluminescence Assay and the Cytometric Bead Array.

J. Organomet. Chem.,2009, 2163-2170. Dioxime and pyridine-2-aldoxime complexes of Re(CO)3+

Dalton Trans., 2008, 3605-3609. Rhenium(I) compounds bound by tripodal ligands of pyridine and N-methylimidazole.

PRESENTATIONS

Multicenter Aids Cohort Study Spring Meeting, Baltimore, MD 2012. Biomarkers ARRA1: Inflammation Markers/Cytokines

Study to Help the AIDS Research Effort (SHARE) February Meeting, Baltimore, MD 2011. MesoScale Discovery and

Biomarkers Longitudinal Study Design

Chemistry Academic Conference, College of the Holy Cross, Worcester, MA 2009. Advanced Research Presentation: Synthesis

and Characterization of Polyamines and Tripodal Ligands with the Re(CO)3+ Metal Core

235th ACS National Meeting, New Orleans, LA, 2008. The synthesis and characterization of glyoxime complexes of Re(CO)3+.

VOLUNTEER Summer 2009

Raised $4,500 for the Johns Hopkins 4K for Cancer organization to fund cancer research and cycled from Baltimore to San

Francisco during the 2009 summer to increase cancer awareness. Mentor current cyclists to prepare them mentally and physically.

LABORATORY SKILLS

Proficient in lab techniques, safety, HPLC, TLC, MS, UV-VIS, IR, NMR, MesoScale Discovery, and liquid robotics

Trained to work with Biohazard level 2 materials.

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