Engineering University

CURRICULUM VITAE OF Mr. KAYEMBE D. JACQUES

Personal details

Surname: DIAINABO

Full name: KAYEMBE JACQUES

Gender: MALE

Marital status: MARRIED

ID No: 681***-****-** 5

Date of birth: 16thnovember1968

Home address, Flat n0 7, Miriam court, 51 High street, Rosettemville,

RSA; cell no: +277*-***-****

E-mail: *************@*****.**

Qualifications

I completed my Ph. D. Studies in polymer chemistry at the University of the

Witwatersrand, South Africa. I am presently busy with my researches on

composite materials made with carbon nanotubes, a polypropylene polymeric

matrix and a natural fibre. I hold an M. Sc. degree of Science in the same

field. During the course of my research, I have been tutoring Maths,

Physics, Chemistry and Mechanics to first and second year engineering

students. Concerning my work, I was committed to design and synthesize

water-soluble polymeric structures to serve as carriers to which anticancer

drugs were to be attached by biofissionable links for deliverance to the

cancer cells. Water solubility was achieved by imparting such solubilising

group functionalities as tertiary amines and hydroxyls in the structure.

Three drugs were selected for this purpose, namely the antifolate

METHOTREXATE, purchased from the store, the organoiron ferrocenylbutanoic

acid, synthesized by a Friedel Craft acylation of ferrocene [di (?5-

cyclopentadienyl)iron (ll)] with succinic anhydride in mehylene chloride,

using aluminium chloride as catalyst, followed by a clemmensen reduction of

the keto-acid obtained, in acid, in a mixture of methanol, hydrochloric

acid, toluene and water, using mercuric chloride as catalyst; and the

platinum complex cisplatin, produced from potassium tetrachloroplatinate.

These synthetic processes involved such chemical subdisciplines as organic,

biochemistry, inorganic and coordination chemistry. Purification of my

samples was achieved by column chromatography and aqueous dialysis, while

their analysis was made possible by NMR, IR, UV and mass spectrometries. I

could establish the killing power of my samples by in vitro test on MCF-7

cancer cell lines. As a researcher, I have been a self-motivated

individual, able to work under little supervision, capable to establish a

professional work environment and to operate within a multidisciplinary

team.

I am fluent in both English and French: conversant in both languages.

BACK GROUND

University of the Witwatersrand: Ph. D. IN CHEMISTRY 2013

University of the Witwatersrand: MASTER'S DEGREE IN CHEMISTRY 2008

University of Lubumbashi: B.Sc Hon. in CHEMISTRY

SINCE 2000

SUBJECTS: CRYSTALOGRAPHY-MINERAROGY

ORGANIC INDUSTRIAL AND INORGANIC CHEMISTRY

TECHNOLOGY OF ORGANIC CHEMISTRY:

SPECTROCHEMISTRY

PHYSICAL CHEMISTRY

PHYSICS

NUCLEAR CHEMISTRY

University of Lubumbashi: B. Sc. in CHEMISTRY- since 1998

SUBJECTS: GENERAL CHEMISTRY

ORGANIC CHEMISTRY

INORGANIC CHEMISTRY

PHYSICS

MATHEMATICS

Tertiary education: CERTIFICATE OF MATRICULATION SINCE 1988

SUBJECTS: MATHEMATICS

PHYSICS

BIOLOGY

CHEMISTRY

Career objectives

Join a professional chemical organisation with national or international

scope, dedicated to a professional advancement. Share my acquire experience

in industrial chemistry with others for the benefit of the organisation.

Promote and motivate team approach to projects. Help improve safety

standards within your chemical service to ultimately lead to greater

profitability, engage in activities, which promote the continued success of

your organisation and our joint efforts.

Other highlights

-Management of the chemical inventories

-Lecturing in chemistry, physics and maths (first and second year

engineering)

-Metal extractions, ore preparation and polymer design and synthesis.

-Animal and vegetable oil extraction and purification for detergents

synthesis.

-Organizing and directing project teams;

-Planning equipments, materials and resources;

-Production control experience.

Software familiarity

MS Office, Microsoft word, Excel, Windows, Power Point, CD burning,

software scanning

Work experience

Name of company: Wits University

Position held: Researcher

Period: 2004-2009

Duties: -design and synthesis of water-soluble polyaspartamides and

plyamidoamines homo and

co-polymers to be used as vehicles in drug delivery

-control of quality of polymers by TLC and spectroscopy (NMR,

UV, IR)

-Purification of polymers by Colon chromatography, using

Sephadex Gel 25.

-Lab technician in charge of the chemical inventory

During my research period, I have been employed as a tutor and demonstrator

in chemistry and physics.

Name of company: Computer College of Lubumbashi (RDC)

Position held: lecturer

Period: 2000-2002

Duties: teaching and marking in chemistry and maths

Conferences attended

*Oral presentations

-Antiproliferative

Activity of Macromolecular Methotrexate

Conjugates against the CEM/S and CEN/S Human

Leukemia

Cell Lines; The 37th national Convention of the

South African

Chemical Institute; CSIR International

Convention Centre;

Pretoria 4-9 July 2004

Polymeric Drug

Carriers of Low Systemic Toxicity; 1ST

Symposium of

BIOMATERIAL SCIENCE AND APPLICATIO IN

SOUTH AFRICA; 04

September 2006

-Macromolecular

antiproliferative agents containing the

organoiron compound ferrocene: 4th workshop of

the anticancer

drug development consortium: PUMULANI LODGE; 3-

4

September 2007

- Preliminary toxicology studies on Carboxyl-

functionalized

polyaspartamides; 2nd ANNUAL SYMPOSIUM OF THE

BIOMATERIAL ASSOCIATION OF SOUTH AFRICA; 26

November 2007

Publications

Polymeric Conjugates of Selected Aminoquinoline Derivatives as Potential

Drug Adjuvants in Cancer Chemotherapy

Authors: Aderibigbe, Blessing1; Jacques, Kayembe2; Neuse, Eberhard3

Source: Journal of Inorganic and Organometallic Polymers and Materials,

Volume 21, Number 2, June 2011, pp. 336-345(10)

Publisher: Springer

General health: Excellent

References

Prof. E.W. Neuse

Professor of macromolecular chemistry

5, Neeron road, Blairgowrie, Randburg

Johannesburg, South Africa

Tel: +271********

Prof Robyn Vanzyl

School of pharmacy and pharmacology

Faculty of Health Sciences

Universtity of the Witwatersrand

E-mail: *****.******@****.**.**

Tel : +271**********

Cell : +278*********

Prof A. Zietsman-Thomas

Director, Academic Developme

Faculty of Engineering and the Built Environmen

University of the Witwatersrand

Johannesburg

Wits 2050

Tel +271*-***-****

Fax 011-***-****

MS. SIZIWE GQOBA

LAB SUPERINTENDANT

Tel: 011-***-****

School of chemistry, WITS UNIVERSITY, Johannesburg

IGNATIA CULLEN

LECTURER OF CHEMISTRY IN FIRST YEAR

UNDERGRADUATE

Tel: 011-***-****

School of chemistry, WITS UNIVERSITY,

Johannesburg

I certify that the information herein submitted is true and fair.

Contact this candidate