Technician Project

Richard Soden

***** ******** ***.

San Diego, CA 92126

619-***-**** - Mobile

*******@*****.***

OBJECTIVE

Seeking a position in the field of biotechnology or

pharmaceuticals.

EDUCATION

University of Wisconsin - Madison

Bachelor of Science, May 1999

Major: Molecular Biology

SKILLS

Drug Discovery Cell culture Cloning

Microarrays TaqMan assays Robotics

Assay development High throughput screening

WORK EXPERIENCE

May 2007 - Senomyx

September 2009 Senior Research Associate San Diego, CA

. Screened compound libraries for flavor

enhancing/blocking compounds using Flipr Tetra.

. Maintained the database used for screening data and

cell/compound tracking information that I uploaded and

analyzed.

. Prepared compound plates for screening using automated

equipment.

. Maintained and performed QC on laboratory instruments.

February 2001 - Genomics Institute of the Novartis Research

Foundation (GNF)

October 2006 Research Associate II San Diego, CA

. Conducted gene expression profiling experiments using

Affymetrix GeneChip microarrays.

. Constructed and managed the entire siRNA library at the

institute.

. Optimized and modified a lentiviral siRNA delivery

system for the creation of a new large scale library at

the institute.

. Discovered novel targets in the SHH & WNT signaling

pathways utilizing genome-scale HT screening (RNAi,

cDNA, shRNA).

. Validated novel targets using various techniques

including TaqMan assays, western blots, etc.

. Screened small molecule libraries in high throughput

(384 & 1536-well plate formats) using cell based assays.

. Developed and performed other assays to further optimize

and validate the lead compounds which have led to 9 pre-

IND compounds.

January 2000 - Baxter

December 2000 Lab Technician II Round Lake, IL

. Screened plasma samples for HIV and hepatitis using

ELISA assays while following GDP, GMP, and SOP

guidelines.

May 1999 - Silliker Laboratories

July 1999 Microbiologist Madison, WI

. Temporary position that involved the analysis of food

and environmental swabs for foodborne pathogens.

PUBLICATIONS

Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D, Zhang J, Soden R,

Hayakawa M, Kreiman G, Cooke MP, Walker JR, Hogenesch JB. A gene atlas of

the mouse and human protein-encoding transcriptomes. Proceedings of the

National Academy of Sciences of the United States of America. 2004 Apr

20;101(16):6062-7

Zeisig BB, Milne T, Garcia-Cuellar MP, Schreiner S, Martin ME, Fuchs U,

Borkhardt A, Chanda SK, Walker J, Soden R, Hess JL, Slany RK. Hoxa9 and

Meis1 are key targets for MLL-ENL-mediated cellular immortalization.

Molecular and cellular biology. 2004 Jan;24(2):617-28.

ACTIVITIES

Achieved the highest rank of Eagle Scout in Boy Scouts, of which less than

1% of Boy Scouts receive.

Designed and supervised a prairie restoration project.

REFERENCES

Available upon request.

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