Quality Assurance Medical
Resume:
CURRICULUM VITAE
Karen Petrosyan, MD, HTL, QIHC, TBS (AATB)
Glendale, CA 91206
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Technical Skills And Special Qualifications
Histopathological Laboratory Management
Quality Control and Quality Assurance Monitoring
Laboratory Safety Management
Development of Laboratory Protocols According to CLIA Standards and
Requirements
Grossing and Transcription of Pathology Specimens
Pathological Diagnosis of Cancer Tissue
Histotechnology
Tissue Archiving and Banking
Design and Execution of New Research Projects
Evaluation and Analysis of Research Data
Development of Advanced Methods and Protocols for Histological and
Immunological Staining
Immunohistochemistry
Implementing and Monitoring Antibody and Reagent Validation Program and
Protocols
Validation of New Immunological Reagents
Evaluation and Recommendation of New Equipment and Reagents
Intra-laboratory and Inter-laboratory Proficiency Testing and Quality
Control Studies
Implementing and Monitoring Research and Development Programs and Future
R&D Development Strategies
Method Validation Program and Protocols
Preparation of Multi-Tissue Blocks
Evaluation and Scoring of Immunohistochemistry Results
FISH Analysis (Tissue Fluorescent In Situ Hybridization)
Evaluation and Scoring of FISH Analysis
DNA Ploidy Analysis
Computerized Image Analysis
Circulating Tumor Cell Analysis (CTC Analysis)
CTC Method Validation and New Antibody Validation for CTC Application
ISH Method Validation and Analysis (In Situ Hybridization)
CISH Method Validation and Analysis (Chromogenic In Situ Hybridization)
Education
1984. Graduated from the Yerevan State Medical Institute.
Professional Certifications
1992. Obtained a certification from Educational Commission for Foreign
Medical Graduates (ECFMG).
2001. Obtained a Certification in Histotechnology from American Society of
Clinical Pathologists and from National Society for Histotechnology
(HTL, ASCP).
2001. Obtained Certification of Tissue Bank Specialist from the American
Association of Tissue Banks (AATB).
Special Qualifications
Qualification in Immunohistochemistry. American Society for Clinical
Pathology Board of Certification (ASCP).
Certificate of Recognition for Satisfactory Completion of CellSearch System
Training, Circulating Tumor Cell Analysis, Veridex, Inc., New Jersey, USA
Certificate of Achievement and Special Training for FISH Analysis, Paraffin
Embedded Tissues, Vysis, Inc., Downers Grove, IL
Certificate of Achievement, Automated Cellular Imaging System, ChromaVision
Medical Systems
Certificate of Achievement, Flow Cytometry, Bone Marrow Morphology and DNA
Analysis, Imapth, Inc., Los Angeles, CA
Certificate of Completion, Shades of Harassment Training Course, Parallax
Education, Los Angeles, CA
Professional Memberships
Member of American Society of Cancer Research
Member of National Society For Histotechnology
Member of American Association of Tissue Banks
Member of Los Angeles Society of Pathologists, Inc.
Professional Experience
2011-Present Project Analyst, Anatomic Pathology Department, Laboratory
Corporation of America, USLABS, Irvine, CA
2008-2011 Anatomic Pathology Department Supervisor, Laboratory
Corporation of America, USLABS, Irvine, CA
2007-2008 Histology Laboratory Supervisor, Specialty Laboratories,
Valencia, CA
2006-2007. Oncology Scientist, Pathway Diagnostics, Inc., Malibu, CA
2000-2004. Quality Assurance Development Technologist, Department of IHC
and Histology, IMPATH Inc, Los Angeles, CA
1995-2000. Research Associate, Breast and Gynecological Cancer Research,
Department of Pathology, Norris Cancer Center, USC School of
Medicine, Los Angeles, CA
1996-1997. Resident Physician, Department of Pathology, LAC-USC Medical
Center, Los Angeles, CA
1993-1994. Resident Physician, Department of Internal Medicine, UCSF-
Fresno, Fresno, CA
1991-1993. Medical Assistant, Good Health Medical Center, Los Angeles, CA
1989-1990. Faculty Member, Department of Pathology, Yerevan Medical
College #2, Armenia
1985-1990. Physician of Internal Medicine, Sevan City Hospital #1, Armenia
1981-1984. Surgery Assistant and Nurse on Duty, Yerevan Center of Oncology
and Radiology, Armenia
Honorable Awards
2001. 27th Annual Symposium/Convention, National Society for
Histotechnology
2001. Honoring Excellence In Histotechnology. Sakura Finetek,
USA.
1999. Russian American Enterprise Council. The Peace and Justice
International Award for The Extraordinary Efforts to Promote
Russian American Commercial and Cultural Exchanges and Peace and
Friendship, and Sharing The Spirit of America, a Composite of
The Dreams and Aspirations of All Peoples and Cultures
Throughout The World.
1997. 22nd Annual Residents' Symposium. Honorable Mention Award in
Recognition of Presentation "Multispecimen Tissue Blocks in
Pathology: An Improved Technique of Preparation."
1981. United Soviet Symposium for the Best Scientific Research
Project of Young Scientists. In Recognition of Presentation
"Influence of Semicarbazide and Sodium Nucleinate on
Posttraumatic Regeneration of Skeletal Muscle."
Publications
2003. Petrosyan K, False Positive Immunoreactivity with the PR88
Progesterone Receptor Antibody.
2002. Patrick Brown, MD, Ph.D., Karen Petrosyan, MD, Antonio
Hernandez, MD and Joel A. Chan, MD. The B-cell Transcription
factors BSAP, Oct-2, BOB.1 and the Pan B-cell Markers CD20, CD22
and CD79a are Useful in the Differential Diagnosis of Classical
Hodgkin Lymphoma.
2002. Petrosyan K, Tamayo R, Joseph D, (2002) Sensitivity of a Novel
Biotin Free Detection Reagent PowerVision+ for
Immunohistochemistry. The Journal of Histotechnology. Special
Edition, 2002.
2002. Petrosyan K, Tamayo R. Comparison of Seven Antibody Dilution
Buffers for Immunohistochemistry. Histologic Technical Bulletin
for Histotechnology. Vol. XXXV, No.1, May 2002.
1999. Petrosyan K., Kaminsky D., Hagerty M., Press M.F. Comparison
of Sixteen Progesterone Receptor Antibodies for the
Immunohistochemical Detection of Receptor in Archival Breast
Tissue Samples. Proceedings of the American Association for
Cancer Research.
1997. Petrosyan K and Press MF. Multispecimen Tissue Blocks in
Pathology: An Improved Technique of Preparation. Lab Invest
77:541-542.
1981. Petrosyan KM Influence of Semicarbazide and Sodium Nucleinate
on Posttraumatic Regeneration of Skeletal Muscle. Journal of
Biology.
1982. Petrosyan KM and Engibarian AA. The Role of the Reactive
Connective Tissue in the Processes of Regeneration of Muscular
Tissue. Actual Issues of Pathology, Materials of the United
Caucasian Conference of Pathology and Physiology.
Meetings and Presentations
2002. 28th Annual Symposium/Convention, National Society for
Histotechnology, Los Angeles, California.
2001. 27th Annual Symposium/Convention, National Society for
Histotechnology. Poster Presentation: Comparison of Seven
Antibody Dilution Buffers for Immunohistochemistry. Los
Angeles, California.
2001. 27th Annual Symposium/Convention, National Society for
Histotechnology (2001). Poster Presentation: Sensitivity of a
Novel Biotin Free Detection System PowerVision + for
Immunohistochemistry. Los Angeles, California.
2001. 27th Annual Symposium/Convention, National Society for
Histotechnology. Poster Presentation: Comparison of
"Biogenex", "Ventana" and "DAKO" Automated Immunostaining
Systems. A Novel Automated Antigen Retrieval System i1000.
Los Angeles, California.
2000. Current Seminars In Immunocytochemistry, American Society of
Clinical Pathology, Redando Beach, California.
1999. 1999 Annual Meeting of American Association for Cancer
Research, San Diego, California.
1997. 22nd Annual Symposium of Los Angeles Society of Pathologists,
Los Angeles, California.
Cancer Research Projects
False Positive Immunoreactivity with the PR88 Progesterone Receptor
Antibody (BioGenex Laboratories Inc.)
Comparison of "Biogenex", "Ventana" and "DAKO" Automated Immunostaining
Systems. A Novel Automated Antigen Retrieval System i1000. IMPATH Inc
Sensitivity of a Novel Biotin Free Detection System PowerVision + for
Immunohistochemistry. IMPATH Inc
Comparison of Seven Antibody Dilution Buffers for Immunohistochemistry.
IMPATH Inc
National Institute for Child Health and Human Development, NO1-HD-3-3175:
"Breast Cancer and the Birth Control Pill: Case-Control Study of
Perimenopausal and Past Oral Contraceptive Use."
US Army Medical Research and Development Command, DAMD17-94-J-4290:
"Genetic Abnormalities in Breast Cancer Tumors: Relationships to
Environmental and Genetic Risk Factors Using Twins."
US Army Medical Research and Development Command, DAMD17-96-1-6156:
"Epidemiology and Molecular Genetic Changes in Breast Carcinoma In Situ."
NIH, National Cancer Institute, 1-RO1-CA-64245: "The Molecular
Epidemiology of Breast Cancer"
Comparison of "DAKO-Envision Plus" and Peroxidase anti Peroxidase Detection
Systems for the Immunohistochemical Detection of Estrogen Receptor,
Progesterone Receptor, C-erb2 Oncoprotein, p53 Tumor Suppressor Gene
Product, Cyclin D1 and CD 31 Angiogenesis Factor in Archival Parafin-
Embedded Tissue Samples.
"Can Molecular Markers Predict Response to Adjuvant Chemotherapy". Case-
Control Study.
TCH Study. Taxotere-Carboplatinum-Herceptin in The Treatment of Metastatic
Breast Cancer. Pilot Study.
P53 Tamoxifen: Assessment of P53 Mutations in Tamoxifen-Associated and
Spontaneous Endometrial Cancer.
LADV: "Locally Advanced Breast Cancer". Pilot Study.
ACIS. Development of Her2/neu Automated Cellular Imaging System.
Her2/neu Beta Site. Collaboration with ChromaVision Medical Systems, Inc.
Inventions
Novel Method and Device for Preparation of Multispecimen Tissue Blocks in
Pathology (1997)
Microscope Slide Protector Device (2001)
Collaborations
Founder and Intermediary Representative of the Research and Academic
Collaboration between Health Ministry of the Republic of Armenia and the
USC School of Medicine
Collaboration with ChromaVision Medical Systems, Inc.: "Development of
Automated Tissue Analysis System (ACIS)"
Teaching Activities
Immunohistochemistry Technology and Applications. USLABS, Irvine, CA
Quality Control of IHC, Practice and Theory, USLABS, Irvine, CA
Instructor of General Pathology, Year II Medical School Students, USC
School of Medicine, Los Angeles, CA
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