Medical Mental Health
Resume:
Seong S. Shim, M.D., Ph.D.
-Curriculum Vitae-
1. PERSONAL DATA
Office Address Home Address
Captain James A. Lovell Federal Health Care 1001 Blackthorn Road
Center (FHCC, Lovell) Riverwoods, IL 60015-3700
Mental Health Department (116A) Phone) 216-***-****
3001 Green Bay Road E-mail) *********@*****.***
North Chicago, IL 60064
Phone) 224-***-****
Fax) 224-***-****
E-mail) *****.****@**.***
EDUCATION AND TRAINING
07/1992 - 06/1994 Fellowship, Schizophrenia Research Program, Yale University
School of Medicine, Department of Psychiatry, New Haven, CT.
Mentor: Benjamin Steve Bunney, M.D.
07/1991 - 06/1992 Residency, Yale University School of Medicine, Department of
Psychiatry, New Haven, CT
07/1988 - 06/1991 Residency, Southern Illinois University School of Medicine,
Department of Psychiatry, Springfield, IL
07/1984 - 05/1989 Ph.D., Southern Illinois University School of Medicine,
Department of Pharmacology (Psychopharmacology),
Springfield, IL.
Mentor: Robert E. Becker, M.D.
03/1975 - 02/1980 M.D., Chung-Ang University Medical College, Medicine Program,
Seoul, Korea
03/1973 - 02/1975 B.A., Chung-Ang University Medical College,
Pre-Medicine Program, Seoul, Korea
2. PROFESSIONAL APPOINTMENTS
ACADEMIC APPOINTMENTS
03/2012 - Present Associate Professor of Psychiatry, Rosalind Franklin University of
Medicine and Science (RFUMS)/Chicago Medical School
11/1999 – 02/2012 Assistant Professor of Psychiatry, Case Western Reserve
University (CWRU) School of Medicine, Cleveland, OH
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03/30/2013
07/1998 - 06/2005 Instructor of Psychiatry
Northeastern Ohio Medical University (NEOMU), Rootstown, OH
05/1997 - 05/2003 Research Assistant Professor of Neurobiology and Pharmacology,
NEOMU, Rootstown, OH
PROFESSIONAL APPOINTMENTS
04/2012 – present Staff Psychiatrist, Mental Health Service, Captain James A. Lovell
Federal Health Care Center (FHCC, Lovell), North Chicago, IL
11/2003 – 02/2012 Staff Psychiatrist, Psychiatric Services 116 A, Cleveland V.A.
Medical Center (CLVAMC), Cleveland, OH
11/1999 – 12/2009 Attending Psychiatrist, University Hospitals Case Medical Center
(UHCMC), Cleveland, OH
07/2000 - 06/2002 Staff Psychiatrist, Center for Families and Children, Cleveland, OH
07/1999 - 06/2000 Attending Psychiatrist, University Hospitals Health System,
Laurelwood Hospital and Counseling Center, Willoughby, OH
03/1995 - 06/1999 Staff Psychiatrist, Mental Health Services, Mansfield Correctional
Institution, Mansfield, OH (J-1 Visa Waiver Program)
3. LICENSURE AND BOARD CERTIFICATE
CERTIFICATIONS
09/1999 Board Certification in General Psychiatry by American Board of
Psychiatry and Neurology certificate #47392 (10/1999 – 12/31/2009)
(maintenance of certification – certified on 03/01/11)
02/1987 ECFMG Certification #314-722-0 permanent
MEDICAL LICENSURE
02/2011-present State of Illinois (036-082240)
09/15/1994-present State of Ohio (35067573)
07/1992-08/1997 State of Connecticut (032036)
(Voluntary cancellation)
05/1991-07/1993 State of Illinois (003-036-82240-01)
(Voluntary cancellation)
1992-present DEA Registration (BS2697780)
4. HONORS AND AWARDS
2008 Award for Excellence in Clinical Service for Veterans, East
Cleveland Vet Center
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03/30/2013
2005 Appreciation and Award for Lectureship at the
International Symposium on Healthy Aging,
Chung-Ang University Medical Center, Seoul, Korea
1990 Award for the Pamela Endowment Prize for
Schizophrenia Research, Southern Illinois University
School of Medicine
1987 Award for Qualification Examination for Ph.D. Degree
with a Distinction, Southern Illinois University School
of Medicine
1979 Scholarship and Award for Academic Excellence,
Chung-Ang University Medical College
1978 Scholarship and Award for Academic Excellence, Chung
Ang University Medical College
5. CLINICAL ACTIVITIES
04/2012 – present Mental Health Department, FHCC, Lovell
07/2011 – 02/2012 Psychiatry Outpatient Service, CLVAMC
03/2010 – 06/2011 Psychiatry Acute Inpatient Service, CLVAMC
01/2007 – 03/2010 Electroconvulsive therapy, CLVAMC
11/2003 – 03/2010 Psychiatry Outpatient Service (focusing on schizophrenia/other
chronic mental illness), CLVAMC
07/2002 – 08/2007 Psychiatry Ambulatory Care, UHCMC
11/1999 – 06/2002 Schizophrenia Program, UHCMC
07/2000 - 06/2002 Outpatient service, Center for Families and Children, Cleveland, OH
07/1999 - 06/2000 Acute Inpatient Unit, University Hospitals/Laurelwood Hospital
03/1995 - 06/1999 Mental Health Services, Mansfield Correctional Institute,
Mansfield, OH
6. TEACHING ACTIVITIES
RFUMS/Chicago Medical School
MEDICAL STUDENT TEACHING
Outpatient Services
Location Year Years Taught Contact/Resident #
FHCC, Lovell 3th year 03/2012-present supervised biweekly/1
PSYCHIATRIC RESIDENT TEACHING
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03/30/2013
Outpatient Services
Location PGY Years Taught Contact/Resident #
FHCC, Lovell 3 03/2012-present supervised weekly/3
CWRU School of Medicine
MEDICAL STUDENT TEACHING
I. Psychiatric Didactic Lectures (3rd or 4th year students)
Lecture Location Years Taught Contact/Year
2000 – 2011
Basics of Schizophrenia UHCMC 13 lectures/yr
2000 – 2011
Antipsychotic Drugs UHCMC 13 lectures/yr
II. Psychiatric Acute Inpatient Clerkship Supervision (3rd /4th year students)
Location Months/Years Supervised Contact/Students #
06/2002 – 09/2002
UHCMC supervised daily/2-3
03/2010 – 06/2011
CLVAMC supervised daily/2
III. Small Group Mentor of Differential Diagnosis based on DSM IV (3rd year students)
Location Months/Years Supervised Contact/Students #
03/2010 – 06/2011
CLVAMC supervised weekly/2-3
IV. Block 6 Clinical Interviewing Supervision (2nd year students)
Location Years Taught Contact/Students #
CLVAMC 2006, 07, 08, 09 yearly/5
PSYCHIATRIC RESIDENT TEACHING
I. Resident Didactic Lectures
Title PGY Years Taught Contact
Research Directions in Schizophrenia 2 2002 - 2011 once per year
Neuroplasticity and Mental Illness 3 2003 - 2011 once per year
Atypicality of Antipsychotic Drugs 3 2003 - 2008 once per year
2010 – 2011
Signal transduction 1 once per year
II. Clinical and Research Supervision
Outpatient Services
Location PGY Years Taught Contact/Resident #
CLVAMC 3 07/2003-02/2010 supervised weekly/1
Inpatient Services
Location PGY Years Taught Contact/Resident #
UHCMC 1/2 07/2001-08/31/2002 supervised daily/1
03/2010 – 06/2011
CLVAMC 1/2 supervised daily/1
Mentored Resident Research and Publication
Imran Abassi, M.D. (PGY 4)
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03/30/2013
Seong S. Shim, Michael D. Hammonds, Imran M. Abassi, Joseph R.
Calabrese: Effects of chronic lithium treatment on long-term potentiation
in area CA1 of the hippocampus. Neurosci Abstr 2006;476.22.
Shim S.S., Hammonds M.D., Abassi I., Calabrese J.R.: Effects of in vitro and
in vivo lithium treatment on long-term potentiation in area CA1 of the
hippocampus. Research Show CASE Abstr 2007;324.
Matthew M. Vrabel, M.D.(PGY 4)
Shim S.S., Hammonds M.D, Vrabel M.M.: Augmentation of Behavioral
Therapy with Glycine Agonists for Obsessive-Compulsive Disorder. Am J
Psychiatry 2008;165:150.
Sri Jatla, M.D.
Jatla S., Shim S.S.: Mood Stabilizers’ Effects on Sleep Review Article (in
preparation).
MENTOR OF FULL TIME POSTGRADUATE RESEARCH ASSOCIATES
Name Years Mentored Location Contact
R.A. Russell, Ph.D. 07/2002–08/2004 UHCMC daily
M. Hammonds, Ph.D. 01/2005–12/2007 CLVAMC daily
7. RESEARCH ACTIVITIES
PRECLINICAL RESEARCH
01/02/2005 – 08/14//2009 (the principal investigator; CLVAMC)
Examined the effects of exposure to lithium and olanzapine on long-term
potentiation, the morphology of dendrites and the levels of BDNF, Bcl-2 and p-
CREB in the hippocampus. This study was supported by Lilly Investigator-
Initiated Research Award.
05/27/2004 – 21/31/2005 (the principal investigator; CLVAMC)
Examined the effects of lithium exposure on synaptic plasticity in the
hippocampus and prefrontal cortex. This study was supported by Cleveland VA
Medical Research and Education Foundation Grant.
07/01/2002 – 08/31/2004 (the principal investigator; CLVAMC)
Examined the effects of phencyclidine exposure on synaptic plasticity in the rat
hippocampus. This study was supported by NIH/NIMH (R03).
CLINICAL RESEARCH
06/01/2012 – present (the principal investigator; FHCC, Lovell)
Conduct research on the effects of lithium on cognitive deficits in veterans with
mild traumatic brain injury. This trial is supported by FHCC. Lovell, Department
of Mental Health.
02/02/2010 – 02/29/2012 (the principal investigator; CLVAMC)
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03/30/2013
Conduct research on effects of lithium on depressive symptoms and blood levels
of BDNF, Bcl-2 and p-CREB in patients with bipolar depression.
This study is funded by Cleveland VA Medical Research and Education
Foundation Award and the Morley Award, Dept. of Psychiatry, CWRU.
08//2007 - 07/2010 (site co-investigator; CLVAMC)
Participated in NIMH-funded, six-sites, collaborative randomized, double-blind
parallel group trial comparing lithium (LI) with divalproex (DV) over 9 weeks in
geriatric patients with bipolar manic and hypomanic episodes as a CLVAMC site
co-investigator (Central PI: Robert Young M.D., site PI: Dr. Martha Sajatovic
M.D. and Co-PI: Peijun Chen, M.D., Ph.D.)
UHCMC/NIMH CENTER FOR BIPOLAR DISORDER
09/2005 – 12/2006 (co-investigator)
Participated in Combination Therapy in Bipolar Rapid Cycling-R21/Stanley
Foundation (PI: Joseph R. Calabrese, M.D.).
09/2005 – 12/2006 (co-investigator)
Joined Abott Laboratory-funded, double-blind, placebo-controlled divalproex
sodium ER in bipolar I or bipolar II depression previously diagnosed and treated
as recurrent major depression (PI: Joseph R. Calabrese, M.D).
8. RESEARCH SUPPORT
Current Funding
The principal investigator
Research Grant
Otsuka/INC Research
Title: A 52-week, multicenter,randomized, double-blind, 2-arm active-controlled,
non-inferiority study to assess the efficacy, safety, and tolerability of an
intramuscular depot formulation of aripiprazole as maintenance treatment in
patients with biipolar I disorder
To investigate the efficacy and safety of apriprazole depot formulation in the
maintenance treatment of bipolar I disorder.
Past Funding
The principal investigator
02/01/2010 – 02/29/2012
Research Grant
Cleveland VA Research and Education Foundation
Title: Neuroplastic action of lithium in treatment of patients with bipolar
depression
Co-I: Peijun Chen, Curtis Tatsuoka, Consultant: Martha Sajatovic
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03/30/2013
To investigate the effects of lithium treatment on the levels of BDNF, Bcl-2 and
phosphorylated CREB in the peripheral blood of patients with bipolar depression.
Research Grant 04/01/2009 - 02/29/2012
2009 John C and Sally S. Morley Family Foundation for Research in Depression
and Post-Depression Treatment, Department of Psychiatry, CWRU
Title: Neuroplastic action of lithium in treatment of geriatric patients with bipolar
depression
Consultant: Martha Sajatovic
To investigate the effects of lithium treatment on the levels of BDNF, Bcl-2 and
phosphorylated CREB in the peripheral blood of patients with bipolar depression.
02/01/2002 – 07/31/2004
Research Grant
NIH/NIMH [R03 MH63404-01]
Title: NMDA Receptor antagonist-induced neurotoxicity in schizophrenia
To investigate the effects of phencyclidine exposure on synaptic plasticity in the
rat hippocampus.
04/23/2005 – 08/14/2009
Research Grant
Lilly Pharmaceutical Co. Investigator-Initiated Research [F1D-US-A128]
Title: Effects of olanzapine on synaptic plasticity
To compare the effects of exposure to olanzapine and lithium on synaptic
plasticity and levels of BDNF, Bcl-2 and phospho-CREB in the rat hippocampus.
05/27/2004 – 21/31/2005
Research Grant
Cleveland VA Medical Research and Education Foundation
Title: Effects of lithium on synaptic plasticity
To investigate the effects of lithium exposure on synaptic plasticity in the
hippocampus and prefrontal cortex.
04/30/2004 – 01/31/2005
Education Grant
Forest Laboratories. Unlimited Education Grant
To review NMDA receptor antagonists as novel psychotropic drugs for
neuropsychiatric disorders.
Submitted
The principal investigator
Research Grant
Merit Review Pilot Projects for Research on Amyotrophic Lateral Sclerosis,
Parkinson’s Disease and Alzheimer’s Disease
Title: Defining early neuronal signaling deficit in AD for novel therapeutic
development
Role: PI
To examine the dysregulation of ER calcium channels as the early pathogenic
processes of Alzheimer’s disease.
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03/30/2013
The co-principal investigator
Research Grant
Department of Defense, Traumatic Brain Injury Research Award DOD-TBIRA
Title: Stabilizing intracellular calcium dysregulation as an acute intervention for
TBI, and as prevention of conversion to dementia
Role: Co-PI (PI: Grace Stutzmann, Ph.D.)
To examine the preventive action of the stabilization of calcium channel by
lithium in conversion of acute TBI to chronic dementia.
9. PROFESSIONAL SERVICES
JOURNAL EDITORIAL BOARD
10/2010 – present The Journal, Pharmacology and Pharmacy (ISSN: 0022-3573)
03/2011 – present The Open Journal of Neuroscience (ISSN: 1874-0820)
JOURNAL ADVISORY BOARD
01/2005 – present The journal, Psychiatric Investigation (ISSN: 1738-3684)
CONSULTANT
05/2005 – 04/2006 Consultant, Forest Laboratories
03/2013 - present Otsuka/Lundbeck EXCEL Bureau Speaker
10. MEMBERSHIP IN PROFESSIONAL SOCIETIES
06/2012 – present RFUMS/Chicago Medical School
Neurodegeneration and Repair Consortium
2008 - present Society of Biological Psychiatry
2008 – present International Society to Advance Alzheimer
Research and Treatment
1988 – present Society for Neuroscience
2001 (also 1988-93) – present American Psychiatric Association
11. COMMITTEES IN MEDICAL SCHOOL, HOSPITALS AND
COMMUNITY
03/30/13-present Chair, DSM-V Study Group, RFUMS/Chicago Medical
School (planning)
08-12/2005, Scientific Review Committee, Department of Psychiatry,
05/2009-02/29/2011 CWRU
01/2005-02/29/2012 Clozapine Treatment Committee, CLVAMC
01/2002-12/2006 Academic Committee, American Korean Association of
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03/30/2013
Psychiatry
01/2007-present Planning committee, Korean American North East Ohio
Medical Association
01/2006-present Volunteer Advisor, Asian American Association in the
Greater Cleveland.
03/2008-present Coordinator, Annual Minority Health Fair, Korean Central
Presbyterian Church
12. BIBLIOGRAPHY
JOURNAL ARTICLES
Peer reviewed articles
1. Shim S.S., Becker R.E.: Roles of monoamine oxidase A and B in metabolism of
serotonin within serotonergic neurons. J Psychopharmacol 1993;7:181-189.
2. Shim S.S., Shi X.-S., Bunney B.S.: Effects of Lesions in the Medial Prefrontal
Cortex on the Activity of Midbrain Dopamine Neurons.
Neuropsychopharmacolgy 1996;15:437-441.
3. Shim S.S.: Action of atypical antipsychotics (letter). Am J Psychiatry
2002;159:154-155.
4. Shim S.S., Adityanjee: Is NMDA receptor hypofunction in schizophrenia
associated with a primary hyperglutamatergic state? (letter). Arch General
Psychiatry 2002;59:466-468.
5. Shim S.S., Adityanjee: Extrapyramidal symptoms associated with quetiapine.
Aust NZ J of Psychiatry 2003;37:773.
6. Shim S.S., Hammonds M., Ganocy S.J., Calabrese J.R.: Effects of lithium
exposure on synaptic plasticity in the dentate gyrus of the hippocampus. Prog
Neuropsychopharmacol Biol Psychiat 2007;31:343-347.
7. Hammonds M.D., Shim S.S., Pingfu F., Calabrese J.R.: Effects of subchronic
lithium treatment on levels of BDNF, Bcl-2 and phospho-CREB in the rat
hippocampus. Basic Clin Pharmacol Toxicol 2007;100:356-359.
8. Nocjar C., Hammonds M.D., Shim S.S.: Chronic lithium treatment magnifies
learning in rats. Neuroscience 2007;150:774-788.
9. Shim S.S., Hammonds M.D., Kee B.S.: Potentiation of the NMDA receptor in the
treatment of schizophrenia: focused on the glycine site. Eur Arch Psychiatry
Clin Neurosci 2007;258:16-27.
10. Gao K., Kemp D.E., Ganocy S., Shim S.S., Findling R.: Calabrese J.R.:
Differential interactions between comorbid anxiety and substance use disorder
in rapid cycling bipolar I or II disorder. J Affect Disord. 2008;110:167-173.
11. Shim S.S., Hammonds M.D, Vrabel M.M.: Augmentation of behavioral therapy
with glycine agonists for obsessive-compulsive disorder (letter). Am J
Psychiatry 2008;165:150.
12. Hammonds M.D., Shim, S.S.: Effects of 4 weeks lithium and olanzapine
treatment on levels of BDNF, Bcl-2 and phosphorylated CREB in the
hippocampus. Basic Clin Pharmacol Toxicol 2009;105:113–119.
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13. Shim S.S.: Lower Serum levels of lithium may produce efficacy without adverse
effects (letter). Am J Geriat Psychiat 2009;17:625.
14. Shim S. S.: Treatment-resistant schizophrenia: strategies for recognizing
schizophrenia and treating to remission. Psychiatric Times August, 2009.
15. Shim S. S., Hammonds M.D., Tatsuoka C., Feng I-J.: Effects of 4 weeks lithium
and olanzapine treatment on synaptic plasticity in hippocampal CA1 area.
Neurosci Lett 2012;524:5-9.
16. Shim S.S., Hammonds M.D.: Four weeks lithium treatment alters neuronal
dendrites in the rat hippocampus. Int J neuropsychopharmacol (Epub ahead of
print 2013 Jan 18 pages 1 to 10).
17. Shim S.S., Hammonds, M.D.: Two weeks lithium treatment alters neuronal
dendrites and dendritic spines in the rat hippocampus (under peer review)
(Manuscripts in preparation)
1. Shim S.S., Lucia A., Van Meter A., Youngstrom E.: Meta-analysis of the efficacy
of NMDA receptor potentiators in the treatment of schizophrenia.
Non-peer reviewed articles
1. Shim S.S., Teyler T.J.: The in vitro hippocampus model of phencyclidine-
Induced neurotoxicity. Methods Finder December 1997.
2. Adityanjee, Shim S.S., Sabhawal J.: Substance abuse and early schizophrenia.
Primary Psychiatry 2000;7:56-60.
BOOK CHAPTER
1. Shim S.S., Gould TD: Neuroprotective and neurotrophic actions of lithium:
Implications for the treatment of bipolar disorder, Alzheimer's disease and
neurodegenerative disorders. In Metals and Neurotoxicity/Neurodegeneration
(Shile Huang, ed), 2010, Research Signpost,.Kerala, India. pp. 232-267.
2. Shim S.S., Lithium Enhances Synaptic Plasticity: Implication for Treatment of
Bipolar Disorder. In Bipolar Disorder, Intechweb, Rijeka, Croatia.
3. Shim S.S., Potentiation of the glycine site of NMDA receptor: implication for
treatment of negative symptoms of schizophrenia. In Neuropsychiatric
Disorders, Intechweb, Rijeka, Croatia - in preparation.
RESEARCH PRESS RELEASE
Society for Neuroscience Annual Meeting, Washington, D.C., 2007: Chronic
exposure to a lithium chow diet enhances LTP in the CA1 subregion of the
hippocampus and magnifies learning in three different spatial learning tasks.
VA Research Currents, Feb. 2008: Lithium gives brain boost to rats: May show
promise for Alzheimer's disease.
ABSTRACTS
Peer-reviewed oral presentations
1. Shim S.S., Nocjar C. and Hammonds M.D.: Chronic lithium treatment magnifies
learning and enhances LTP in area CA1 of the hippocampus. 2008
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International Conference on Alzheimer’s Disease, Annual Meeting, Chicago,
IL. July 28 – 30, 2008. Alzheimers Dement 2008;4:T115.
2. Shim S.S., Hammonds M.D., Nocjar C.: Lithium enhances synaptic plasticity and
learning. 2009 Society of Biological Psychiatry Annual Meeting, Vancouver,
Cananda, May 14-16, 2009. Biol Psychiatry 2009;64:89S.
Peer-reviewed poster presentations
1. Shim S.S., Becker R.E.: The roles of MAO A and B in serotonin metabolism and
uptake. 1989 American College of Neuropsychopharmacology Annual
Meeting. Hawaii, Dec. Neuropsychopharmacology Abstr 1989.
2. Shim S.S., Russell R., Delgado P.: Effects of exposure to lithium on
electrophyiological responses in the hippocampus. 2003 American College of
Neuropsychopharmacology Annual Meeting, Puerto Rico, Dec. 7 – 11,
Neuropsychopharmacology Abstr 2003;28:S223.
3. Shim S.S., Russell R.: Exposure to lithium enhances synaptic plasticity in the
hippocampus. 2004 American Psychiatric Association Annual Meeting, New
York, NY, May. American Psychiatric Association Abstr 2004.
4. Shim S.S., Russell R.: Effects of exposure to lithium on morphology of dendrites
in the hippocampus and the parietal cortex. 2004 American College of
Neuropsychopharmacology Annual Meeting, Puerto Rico, Dec.12 – 16,
Neuropsychopharmacology Abstr 2004;29:S208.
5. Shim S.S., Hammonds M., Calabrese J.S.: In vivo effects of lithium on synaptic
plasticity and levels of BDNF and p-CREB in hippocampus. 2005 American
College of Neuropsychopharmacology Annual Meeting,Waikoloa, Hawaii.
Dec 11-15. Neuropsychopharmacology Abstr 2005;30:S239.
6. Shim S.S., Hammonds, M.D.: Effects of treatment with olanzapine and lithium on
synaptic plasticity and levels of BDNF, Bcl-2 and phosphorylated CREB in
the hippocampus. 2009 Society of Biological Psychiatry Annual Meeting,
Vancouver, Canada. May 14-16, 2009. Biol Psychiatry Abstr 2009;64:28S.
7. Shim S.S., Hammonds M.D.: Effect of chronic lithium treatment on morphology
of dendrites in hippocampus and prefrontal cortex. 2010 Society of Biological
Psychiatry Annual Meeting, New Orleans, Louisiana May 20-22. Biol
Psychiatry Abstr 2010;67:238S.
Poster presentations
1. Shim S.S., Becker R.E.: The roles of MAO A and B in the control of
intrasynaptosomal concentration of serotonin in rat brain. 1988 Society
forNeuroscience, Annual Meeting, Toronto, Canada, Nov. 13-18. Soc.
Neurosci Abstr 1988.
2. Shim S.S., Becker R.E.: The effects of Inhibition of MAO activity on
synaptosomal uptake of serotonin. 1988 Society for Neuroscience, Annual
Meeting, Toronto, Canada, Nov. 13-18. Soc Neurosci Abstr 1988.
3. Shim S.S., Shi W.-X., Bunney B.S.: Lesioning the medial prefrontal cortex
decreases midbrain dopamine neuron activity. 1994 Society for Neuroscience,
Annual Meeting, Miami Beach, Florida, Nov. 13-18. Soc Neuroci Abstr 1994.
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4. Shim S.S, Teyler T.J.: In vitro model of N-methyl-D-asparate receptor antagonist-
induced neurotoxicity. 1998 Society for Neuroscience Annual Meeting, Los
Angeles, California, Nov. 7-12. Soc Neuroci Abstr 1998.
5. Shim S.S., Teyler T.J.: Acute and subchronic administrations of phencyclidine
impair electrophysiological responses in the hippocampus in vitro. 2000
Society for Neuroscience Annual Meeting, New Orleans, Louisiana, Nov. 4-9.
Soc Neuroci Abstr 2000;92:2.
6. Shim S.S., Russell R.: Exposure to phencyclidine impairs electrophysiological
responses in hippocampal slices. 2003 Research Show. April 13-14. CASE
Abstr 2003;527.
7. Russell R, Shim S.S.: Environmental effects on short-term potentiation (STP) and
long-term potentiation (LTP) across the life span of wistar rats. 2003 April 13
– 14, Research Show. CASE Abstr 2003;112.
8. Russell R, Shim S.S.: In vivo effects of lithium on synaptic plasticity in the
hippocampus. 2003 Society for Neuroscience Annual Meeting, New Orleans,
Louisiana, Nov. 8-1. 2. Soc Neuroci Abstr 2003;850:10.
9. Shim S.S., Russell R.: Exposure to lithium alters electrophysiological responses
in the hippocampus: a morphological study. 2004 Research Show, April 8–9.
CASE Abstr 2004;527.
10. Shim S.S., Russell R., Hammonds, M.D.: Effects of exposure to lithium on
functional and morphological synaptic plasticity in hippocampus. 2005
Society for Neuroscience Annual Meeting, Washington, DC, Nov. 12-16. Soc
Neuroci Abstr 2005;793:2.
11. Shim S.S., Hammonds M.D., Abassi I., Calabrese J.R.: Effects of chronic lithium
treatment on long-term potentiation in area CA1 of the hippocampus. 2006
Society for Neuroscience Annual Meeting, Atlanta, Georgia, Oct. 14-18. Soc
Neurosci Abstr 2006;476.22.
13. Shim S.S., Hammonds M.D., Abassi I., Calabrese J.R.: Effects of in vitro and in
vivo lithium treatment on long-term potentiation in area CA1 of the
hippocampus. 2007 Research Show CASE April 11 - 12. Abstr 2007;324.
14. Shim S.S., Nocjar C. and M. Hammonds M.: Chronic Exposure to a lithium chow
diet enhances LTP in the CA1 subregion of the hippocampus and magnifies
learning in three different spatial learning tasks. 2007 Society for
Neuroscience Annual Meeting, San Diego, California, Nov. 3-7. Soc Neurosci
Abstr 2007;49.18.
15. Halwani G., Quasem I.., Nehaul K., Kotick J.D., Kalmbach K., Shim S. S. and
Mervis R.F.: The Effect of chronic lithium chloride on dendritic branching in
the adult rat neocortex and hippocampus. 2007 Society for Neuroscience
Annual Meeting, San Diego, California, Nov. 3-7. Soc Neurosci Abstr
2007;267.16.
16. Shim S.S., Nocjar C., and Hammonds M.D.: Chronic lithium treatment magnifies
learning and enhances LTP in area CA1 of the hippocampus. 2008 Research
Show April. 16 – 17. CASE Abstr 2008;416.
17. Kim T, Bryan K, Reeves J, Mudd J, Lee H-g, Smith MA, Camins A, Pallas M,
Shim SS, Casadesus G.; Low doses of Lithium Chloride improve cognition
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and neuronal function in the age-accelerated SAMP8 mouse. 2008 Research
Show April 16 – 17. CASE Abstr 2008;143.
18. Shim S.S. and Hammonds M.D, Chronic exposure to a lithium chow diet
enhances the density of dendritic branches in the hippocampus and preforntal
Cortex. 2009 Society for Neuroscience Annual Meeting, Chicago, Illinois, Oct.
17-2. Soc Neurosci Abstr 2009;646.27/W1.
INVITED PRESENTATIONS
Regional
1. CWRU School of Medicine, UHCMC, Departmental of Psychiatry:
“Neuroplasticity in mood disorders”, Aug., 2003.
2. NEOM, Department of Neurobiolgy Seminar, “Neurobiology of schizophrenia”
May,1998.
3. Center for Translational Neuroscience, CWRU: Neuroplastic Mechanism of
Action of Lithium. May 17, 2006.
4. Grand Round, Cleveland Clinic, Department of Psychiatry: Dysfunctional
Neuroplasticity and Bipolar Disorder. Jan. 18, 2007.
5. Grand Round, Northeast Behavioral Health System: Neuroplastic Actions of
Lithium in Treatment of Bipolar Disorder and Alzheimer’s Disease. Mar. 14,
2008.
6. Grand Round, MetroHealth Medical Center, Department of Psychiatry:
Neuroplastic Actions of Lithium in Treatment of Neurodegenerative
Disorders. Mar. 17, 2010.
National
1. 4th Annual Meeting, American Korean Association of Psychiatry, “A
Neurobiological model of Hwa-Byung-‘culture-bound’ anger syndrome” New
York NY, May 6, 1994.
2. 14th Annual Meeting, American Korean Association of Psychiatry, “A Review:
Neuropsychopharmacology in psychiatric practice” New York NY, May 4,
2004.
3. Minisymposium, Pfizer Pharmaceutical Laboratories: "Neuroplasticity in mood
disorders and schizophrenia”. Ann Arbor MI, July 22, 2004.
International
4. International Symposium, Chung-Ang University Medical College
"Neuroplasticity in mental disorders". Seoul, Korea, Oct. 5, 2004.
5. International Symposium, Chung-Ang University Medical Center "Depression as
a neurodegenerative disorder", Seoul, Korea, Jan.23-24, 2005.
6. Asian Society Against Dementia, 3rd Annual International Congress "Chronic
lithium treatment enhances spatial learning and memory". Seoul, Korea. Oct.
11-13, 2009.
GRAND ROUNDS
CWRU-UHCMC, CLVAMC
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7. CWRU School of Medicine, UHCMC, Departmental of Psychiatry:
“Neuroplasticity in mood disorders”, Aug., 2003.
8. CLVAMC Grand Round: “Neuroplasticity and mood disorders” Nov., 2003.
9. CWRU School of Medicine, UHCMC, Department of Psychiatry: “Dysfunctional
neuroplasticity and bipolar disorder”. Aug., 2006.
10. CLVAMC Grand Round: “Dysfunctional neuroplasticity and bipolar disorder”
Sept., 2006.
11. CWRU School of Medicine, UHCMC, Department of Psychiatry: “Dysfunctional
neuroplasticity and bipolar disorder”. Aug., 2006.
12. CLVAMC Grand Round: Neuroplastic Actions of Lithium in Treatment of
Bipolar Disorder and Alzheimer’s Disease. 07/11/2008.
13. CWRU School of Medicine, UHCMC, Department of Psychiatry: Neuroplastic
Actions of Lithium in Treatment of Bipolar Disorder and Alzheimer’s Disease.
01/16/2009.
Regional
Cleveland Clinic, Department of Psychiatry: Dysfunctional Neuroplasticity and
Bipolar Disorder. 01/18/ 2007
Northeast Behavioral Health System: Neuroplastic Actions of Lithium in
Treatment of Bipolar Disorder and Alzheimer’s Disease. 03/14/2008.
MetroHealth Medical Center, Department of Psychiatry: Neuroplastic Actions of
Lithium in Treatment of Neurodegenerative Disorders. 03/17/2010
JOURNAL ARTICLE REFEREE
2012 Neuroscience Letters
2011 Psychiatric Investigation
Psychiatric Investigation
2010 Psychiatric Times
2009 Pharmacology, Biochemistry and Behavior
Pharmacology, Biochemistry and Behavior
Pharmacology, Biochemistry and Behavior
Progress in Neuro-Psychopharmacology & Biological Psychiatry
Psychiatric Times
Psychiatric Research
2008 Biological Psychiatry
Progress in Neuro-Psychopharmacology & Biological Psychiatry
Life Sciences
Neuroscience Letters
Neuroscience Letters
2007 Brain Research
International Journal of Neuropsychopharmacology
2006 Basic and Clinical Pharmacology and Toxicology
2005 Biological Psychiatry
14
03/30/2013
RESEARCH GRANT REVIEWER
2011 Alzheimer's Association, International Research Grant Program
2012 Alzheimer's Association, International Research Grant Program
15
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