Medical Device Human

Ling Zheng Phelan

**** ******** ***, ******* ***, OH 45011

Cell phone: 609-***-****

Email: ********@*****.*** &

*****.******@*******.***

Permanent Resident

Seeking Histopathologist Position

PROFILE

. Histopathologist with histopathology training in Master and Ph.D

programs and experience of necropsies and histopathological evaluation

. Research scientist with postdoctoral bench experience in extensive

scientific fields including immunology, biology, microbiology and

chemistry.

. Industrial histopathological lab experience including charactering

human and animal models using histopathologic methods, including

routine histologic sectioning/staining and immunohistochemical assays

and imaging analysis.

. Experience in medical device company including translational

activities from R&D to commercialization, R&D report and protocol

writing and supporting QC and GLP guideline

PROFESSIONAL EXPERIENCE

Biocure Inc, Norcross, GA

2010-Present

Associate scientist

Provide technical supports including biology and histopathology

University of Florida, Gainesville, FL

2008 - 2009

Postdoctoral Associate

Charactering TRIP-Br2 knockout mice model:

1. Tissue collection, embedding/ processing/ sectioning frozen and

paraffin tissues

2. Whole-organ pathology scanning in TRIP-Br2 knockout mice.

2. Establishing immunoassays and microscopy image system.

Schering-Plough Research Institute, Kenilworth, NJ

2006 - 2008

Postdoctoral Fellow

Searching and validating candidate drug targets in the early psoriasis

model:

1. Dissect serial cryosections of human skin biopsies.

2. Optimize multiple-labeling immunochemical assays with a wide range

of antibodies, including immunofluorescent and chromogenic assays.

3. Validate immunohistochemical quantification by a digital computer-

assisted method.

National University of Singapore, Singapore

2004 - 2006

Research Associate

Recovery of skeletal muscle in a completely lacerated muscle after

repairing the transected main intramuscular nerve Branch:

1. Perform surgery repair on rat models of muscle laceration,

including nerve repair (epiperineural stitches) and muscle repair

(Kessler stitches and running suture).

2. Extract RNA from the muscle tissue.

3. Analyze gene expression profiles of growth factors utilizing Super

Array technique and RT-PCR.

Qingdao Municipal Hospital, Qingdao, Shandong, P.R.China

1998 - 2000

Residency in Pathology

EDUCATION

National University of Singapore, Singapore

2006

Ph. D, Renal Immuno-histopathology, Department of Pathology

GPA: 3.44. Dissertation: Pathogenic mechanisms in the development of lupus

nephritis with human renal biopsies.

Medical School of Shandong University, Jinan, Shandong Province, P.R.China

1998

Master of Science, Renal Pathology

Dissertation: Expression of apoptosis-related genes-Fas, Bcl-2 and Bax in

human glomerulonephritis.

Medical School of Shandong University, Jinan, Shandong Province, P.R.China

1995

Bachelor of Science, Medicine

PUBLICATION SUMMARY

"Rise in dermal CD11c+ dendritic cells associates with early-stage

development of psoriatic lesions." Archives for Dermatological Research.

2012; 304(6):443-449.

"The pathogenic role of NF-kappaB activation in tubulointerstitial

inflammatory lesions in human lupus nephritis." J Histochem Cytochem. 2008,

56(5):517-529.

"Renal tubular cell apoptosis and proliferation may be linked to NF-kappaB

activation and expression of inducible nitric oxide synthase in patients

with lupus nephritis." Human Pathol. 2006, 37(6): 637-647.

"In situ glomerular expression of activated NF-kappaB in human lupus

nephritis and other non-proliferative proteinuric glomerulopathy." Virchows

Arch. January 2006, 448(2):172-183.

"Cut Intramuscular Nerve Affects the Recovery in the Lacerated Skeletal

Muscle." J Orthop Res. 2006, 24(1):102-111.

"The role of intramuscular nerve repair in the recovery of lacerated

skeletal muscles." Muscle Nerve. 2006, 33(3):377-383.

"The impact of microanastomosis of the intramuscular nerve branch on the

healing of a completely lacerated skeletal muscle: a histopathological

analysis." Ann Acad Med Singapore. 2004, 33 (5 Suppl):S24-6

WORKSHOPS

* Protein chemistry and molecular cloning - University of Florida,

Gainesville, 2009.

AWARDS AND SCHOLARSHIPS

* Young Investigator's Award - National Healthcare Group (NHG) of

Singapore, 2004.

* Research scholarship - National University of Singapore, 1999 - 2004.

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