Medical Management

Xiaoli Cui M.D., Ph.D.

**** ***** *** ****** **********@*****.*** Home (901) 214-

5572

Memphis, TN 38120 Cell 901-***-****

EDUCATION

**** **.*., **** ********** School of Medicine, Japan

1982 M.D, GuangXi Medical University, P. R. China

MEDICAL PRACTICE EXPERIENCE

1990-1993 CLINICAL PHYSICIAN

Departments of the Obstetrics and Gynecology, Kobe University School of Medicine, Kobe,

Japan and Department of Obstetrics and Gynecology, in GuangXi Medical University Hospital,

Nanning, P.R. China

1991.4.-1993.4. BIOMEDICAL LABORATORY CHIEF, RESEARCH SCIENTIST

Research laboratory of Obstetrics and Gynecology Department, Nanning, GuangXi Medical

University, P. R. China

• Performed a variety of routine clinic biochemical study of the effects of nutrients and human

placental hormones, supported by a Research Career Development Award issued by

Ministry of Education, P. R. China.

• Supervised clinic staffs and graduate students on identified and evaluated intrauterine fetal

distress by Color Doppler; estimated velocimetry of uterine and umbilical arteries, supported

by a Research Foundation for Youth Scientist Award issued by Ministry of Health of

China (Cui, X. 1992-1995, grant No.1189018)

1985.12.-1991.3. BIOMEDICAL RESEARCH ASSOCIATE

Ph.D., and Medical Practitioner Training Program in the Obstetrics and Gynecology

Department, Kobe University School of Medicine, Kobe, Japan

• Biochemical characterization of molecular weight of chorionic gonadotropin differences

between urinary and blood samples in trophoblastic diseases by using ELISA assays to

accurately diagnose invasive moles / choriocarcinoma in GYN oncology.

• Determined the role of nutritions and placental hormone levels in pregnancy with

intrauterine fetal growth retardation and compared with the level of neonatal blood nutrients

as long term follow-ups on infant growth and their physical development prediction.

• Analysis of the pathophysiological alterations of utero-placental-fetal blood flow by

performing ultrasound pulse Doppler technique on monitoring maternal-fetal hemodynamics

in normal/high risk pregnant women to estimate intrauterine fetal well-being during

pregnancy.

1983-1985 MEDICAL DOCTOR RESIDENT

Department of Obstetrics and Gynecology, in GuangXi Medical University Hospital, Nanning,

P.R. China

1981-1982 MEDICAL INTERNSHIP

Rotation among Departments of Internal Medicine, General Surgery; Pediatrics, Emergency

Room, and Obstetrics and Gynecology Affiliated Hospital of GuangXi

Medical University, Qinzhou, GugangXi, P. R. China

TRANSLATIONAL AND BASIC RESEARCH EXPERIENCE

1998.2.-present. LABORATORY SPECIALIST, then SCIENTIFIC MANAGER

Department of Pathology, St. Jude Children’s Research Hospital, Memphis, Tennessee

• Drug identification of small molecule inhibitor screening of ALK, Menin, and MLL genes

and monitored drug toxicity in animals.

• Performed all of the initial study in discovery and vetting new research projects in the lab.

• Supervised postdoctoral fellows who subsequently assumed the projects; making sure of their

efficient completion and troubleshooting when it is necessary.

• Provided routinely on written reports of data and procedure protocols for the lab members to

use.

• Designed and made plasmid constructs including bacteria, viral, insect cells and

recombination engineering system.

• Characterized the biochemical/functional of NPM-ALK and NPM-MLF1 fusion genes.

• Cloned genes such as normal ALK receptor tyrosine kinase and the MLF1, BCL10.

• Gene profiled RBM15 and MKL1, in the t(1;22)(p13;q13) of pediatric acute megakaryoblastic

leukemia.

• Database management of lab supply inventory; follow-through laboratory notes, data reports,

and documental records.

• Interviewing new technicians for hiring.

• Training staff on Dangerous Goods Shipping.

• Responsible for all day-to-day aspects of the lab management.

1995.5.-1998.1. SENIOR LABORATORY TECHNOLOGIST

Department of Experimental Oncology, St. Jude Children’s Research Hospital, Memphis,

Tennessee

• Cloned and characterized the BCL10 gene in MALT lymphomas.

• Generation of transgenic BCL10 and ALK KO mice as well as genotyping and mice

management.

• Initiated and established the two-hybrid system for BCL10 and ALK genes.

• Generated a number of immunological assay system in the lab to fully characterize the Bcl10

gene with K/O mice.

1994.3.-1995.5. POSTDOCTORAL RESEARCH FELLOW

Department of Pharmacology, University of Tennessee, Memphis, Tennessee

• Identification of a glucocorticoid repressor domain in the promoter region of the B1-

adrenergic receptor gene;

• Determination of sequences required for the transcriptional regulation of expression of the

rat B1-adrenergic receptor gene.

• Isolated and performed primary cell culture of rat cardiomyocytes.

• Animal management.

HONORS AND AWARDS

1992-1995 Research Foundation for Youth Scientist Award issued by Ministry of

Health of China (Cui, X. 1992-1995, grant No.1189018)

1992-1993 Research Career Development Award issued by Ministry of Education,

P.R.China

1991-1993 Associate professor in Department of OB/GYN, GuangXi Medical University,

P. R. China

1985-1991 International Exchange Scholarship from GuangXi Province, P. R. China to

support research and living in Japan

1988-1991 Betahomu International Research Awards from Betahomu Club, Osaka, Japan

to support living in Japan

1990-1991 Foreign Medical Practitioner Training Program, Ministry of Health of Japan

to permit for one year clinic practice in Japan

1977-1982 Excellent Student Awards for each academic year in GuangXi Medical

University, P. R. China

Government selected excellent student to be working in GuangXi

1982-1985

Medical University Hospital (a top medical university hospital in the province).

PROFESSINAL MEMBERSHIPS

Member of American Society of Hematology (2003-present)

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