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Engineering Mechanical

Location:
Boston, MA
Posted:
February 08, 2013

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Resume:

Curriculum Vitae Jeffrey W. Ruberti, August ****

Jeffrey W. Ruberti, Ph.D.

*** ***** *********** ****** ** 617-***-****

Department of Mechanical and Industrial Engineering fax617-***-****

Northeastern University abqohs@r.postjobfree.com

Boston, MA

EDUCATION

Northwestern University - Evanston, IL Jan 2000 - July 2001

Postdoctoral Fellow, Dept. of Biomedical Engineering - Nanostructural visualization of lipids in

macula, nanoscale transport and micropressure measurements.

Massachusetts Institute of Technology - Cambridge, MA April 1998 - Jan 2000

Postdoctoral Associate, Department of Mechanical Engineering - Visualization of extracellular

matrix nanostructure, nanoscale transport mechanics and theoretical treatment of corneal soluble

molecule distribution.

Tulane University - New Orleans, LA April 1998

Ph.D. in Biomedical Engineering

Theoretical and computational treatment of transport and swelling in biological membranes

(e.g. cornea).

Tulane University - New Orleans, LA May 1986

B.S.E. Biomedical Engineering

Phillips Academy - Andover, MA June 1982

EMPLOYMENT (INDUSTRY)

2001-2004 Cambridge Polymer Group, Inc. Boston, MA

Associate Consultant. Direct, perform and develop tests to characterize polymer

systems. Research biological applications of polymers including rheological behavior of

curing polymers, methods to strengthen hydrogels and generation of artificial cornea de

novo. Principal Investigator on Phase I SBIR awarded to develop artificial corneal

stroma.

12/89-8/91 Hamilton Sunstrand, Space and Sea Systems (UTC) Windsor Locks, CT

Senior Experimental Engineer. Life support systems engineering lead on the

International Space Station Potable and Hygiene Water Processing system. Aided in

design of novel zero-gravity water separator that is operational on the International

Space Station.

6/88-12/89 Southwest Foundation for Biomedical Research San Antonio, TX

Research Associate - Biomedical Engineer. Provided engineering support to

Department of Physiology and Medicine (pulmonary function measurements).

Curriculum Vitae Jeffrey W. Ruberti, August 2010

Constructed clinical high frequency ventilation monitoring system for neonates.

Designed automated pulmonary function test system.

10/86-6/88 Sikorsky Aircraft (UTC) Stratford, CT

Systems Engineer - Avionics Mission Tactical Systems (anti-submarine warefare).

Responsible for the integration of various advanced avionics and tactical systems into

the SH-60F (CV-Helo). Designed electromagnetic interference shielding system for

instrument panel on UH-60 Blackhawk Helicopter.

EMPLOYMENT/APPOINTMENTS (ACADEMIC)

2009-present Northeastern University, Graduate School of Engineering Boston, MA

Coordinator of the interdisciplinary graduate group for Bioengineering. Recently

appointed to lead Northeastern s new interdisciplinary Ph.D. program in

Bioengineering. Responsibilities include: Curriculum development/maintenance,

admissions, staffing, development of program resources and student advising/evaluation.

The program currently has 94 affiliated faculty distributed across three colleges.

2004-present Northeastern University, Department of Mechanical and Industrial Eng .

Boston, MA

Associate Professor. Research focus on Biomechanics, Mechanobiology and Tissue

Engineering

2001-present Schepen s Eye Research Institute, Ocular Surface Group Boston, MA

Adjunct Scientist. Consult and assist in efforts to construct cornea grown from human

cells. Perform high resolution imaging of nanoscale structure of secreted stromal matrix.

2003-2006 Massachusetts Eye and Ear Infirmary, Harvard University Boston, MA

Lecturer. Disseminate research results to Ophthalmology fellows.

8/00-8/01 Northwestern University, Dept of Biomedical Engineering Evanston, IL

Research Associate Performed micropressure measurements in extracellular matrix

and used high resolution Quick Freeze Deep Etch imaging to examine lipid

accumulation with age in the macula of the eye.

4/98-4/99 Boston University Medical School, Dept of Ophthalmology Boston, MA

Consultant Assisted in the preparation and visualization of corneal and trabecular

meshwork nanostructure using Quick Freeze/Deep Etch technique.

5/93 - 8/94 Tulane University, Dept of Biomedical Engineering New Orleans, LA

Research Assistant - Investigated turbulent blood flow in models of Abdominal Aortic

Aneurysms.

8/91 - 5/93 Tulane University, Dept of Biomedical Eng New Orleans, LA

Curriculum Vitae Jeffrey W. Ruberti, August 2010

Teaching Assistant . Assisted in the instruction of undergraduate physiology for

engineers. Instructed laboratory and graded lab reports.

SCHOLARSHIP

Quick summary (total record):

Total published works: 102

Published works count includes:

Peer-reviewed journal articles: 22

Chapters/Reviews: 3

Abstracts/Conference Papers: 69

Issued Patents: 4

Published Patent applications: 4

Not included in published works count:

Journal articles under review: 4

Manuscripts in high state of preparation: 5

Dr. Ruberti s H-INDEX: 12 (Calculated via ISI Web of Science)

Total citations: 373; Average Citations per year: ~22, Citations last year: ~78

Top 3 cited papers: Collier et al 2001 (89), Ruberti et al 2003 (36), Switkes and Ruberti 2004 (31)

PEER-REVIEWED JOURNAL ARTICLES

J1. Flynn BP, Bhole A, Saeidi N, Liles M, DiMarzio C and JW Ruberti (2010). Mechanical strain

stabilizes reconstituted collagen fibrils against enzymatic degradation by mammalian

collagenase Matrix Metalloproteinase 8 (MMP-8) (IN PRESS at PLoS ONE).

J2. Zareian R, Church KP, Saeidi N, Flynn BP and JW Ruberti (2010). Probing collagen/enzyme

mechanochemistry in native tissue with dynamic, enzyme-induced creep. Langmuir

26(12):9917-26. 5 year impact factor (5YIF 2.52)

J3. Saeidi N, Sander E and JW Ruberti (2009). Dynamic shear influenced collagen self-assembly

Biomaterials Dec 30,(34):6581-6592. 5YIF - 7.33

J4. Ruberti JW and JB Sokoloff (2009) A polymer brush model of load support by articular

cartilage. (In review at Biomacromolecules). IF 4.146

J5. Saeidi N, Portale K and JW Ruberti (2009). Confined, concentrated collagen is a cooperative

load-bearing engineering material. (In review at Biomaterials) 5YIF 7.33

J6. Guo XQ, Saeidi N, Hutcheon AEK, Melotti SA, Zieske JD, Trinkaus-Randall V and JW

Ruberti (2009). Collagen deposition by ascorbic acid-stimulated human corneal fibroblasts

onto (and within) reconstituted collagenous substrates. (Under revision at Investigational

Ophthalmology and Visual Science) 5YIF 3.83

J7. Bueno EM, Saeidi N, Melotti SA and JW Ruberti (2009) Effect of Serum and Insulin

Modulation on the Organization and Morphology of Matrix Synthesized by Bovine Corneal

Stromal Cells. Tissue Engineering Part A, Volume 15 (Epub ahead of print) 5YIF 4.87

J8. Bhole AP, Flynn BP, Liles M, Saeidi N, DiMarzio CA and JW Ruberti (2009) Mechanical

strain enhances survivability of collagen micronetworks in the presence of collagenase:

Curriculum Vitae Jeffrey W. Ruberti, August 2010

Implications for load-bearing matrix growth and stability. Philosophical Transactions of the

Royal Society A Sept 13, 367(1902):3339 -3362. (Invited) 5YIF 2.46

J9. Bueno EM and JW Ruberti (2008). Collagen transport through track -etched nanopores.

Journal of Membrane Science Aug 15, 321:250-263. 5YIF 3.67

J10. **Ruberti JW and JD Zieske (2008). Prelude to corneal tissue engineering Gaining control

of collagen organization. Progress in Retinal and Eye Research Sept 27(5):549-577. 5YIF

8.5 By invitation leading experts write on basic and clinical aspects of the eye in a style

appealing to molecular biologists, neuroscientists and physiologists, as well as to vision

researchers and ophthalmologists. Highest ranked journal in Ophthalmology

J11. Ren, R, Hutcheon AEK, Guo XQ, Melotti SA, Ruberti JW, Zieske JD and V Trink aus-

Randall. (2008). Human primary fibroblasts synthesize and deposit proteoglycans in long-term

3-D cultures. Developmental Dynamics Oct; 237(10):2705 -2715. (Invited) 5YIF 3.13

J12. Guo X, Hucheon AEK, Melotti SA, Trinkaus-Randall V, Zieske JD and JW Ruberti (2007).

Morphological characterization of organized extracellular matrix deposition by ascorbic acid

stimulated human corneal fibroblasts. Investigational Ophthalmology and Visual Science 48

(9):4050-4060. 5YIF 3.83

J13. Ruberti JW and NJ Hallab, Strain controlled enzymatic cleavage of collagen in loaded

matrix. Biochemical Biophysical Research Communications 2005 Oct 21; 336(2):483 -489

5YIF 2.82

J14. Li LY, Tighe BJ, and JW Ruberti. Mathematical modelling of corneal swelling.

Biomechanics and Modeling Mechanobiology 2004 Nov 3(2):114 -123. IF 3.13

J15. Switkes M and JW Ruberti. (2004) Effect of surface properties and dissolved gas on the

evolution of nanobubbles at submerged surfaces. Applied Physics Letters 84, 4759-4761 5YIF

4.10

J16. Bass EC, Wistrom EV, Diedrich CJ, Nau WH, Pellegrino R, Ruberti JW and JC Lotz. Heat

induced changes in annulus fibrosu s mechanics. Journal of Biomechanics 2004 Feb;

37(2):233-240 5YIF 3.52

J17. Muratoglu OK, Ruberti JW, Melotti SA, Spiegelberg SH, Greenbaum ES and WH Harris.

Optical analysis of surface changes on early retrievals of highly crosslinked and conventional

polyethylene tibial inserts. Journal of Arthroplasty . 2003 Oct;18(7 Suppl 1):42 -47 5YIF

2.056

J18. Pederson AW, Ruberti JW and PB Messersmith (2003). Thermal assembly of a biomimetic

mineral/collagen composite. Biomaterials 24, 4881-4890. 5YIF - 7.33

J19. Ruberti JW, Curcio CA, Millican L, Menco BPhM, Huang JD and M. Johnson (2003).

Quick-freeze/deep etch visualization of age-related lipid accumulation in Bruch s membrane.

Investigational Ophthalmology and Visual Science 44(4): 1753-1759 5YIF 3.83

J20. Gong H, Ruberti JW, Overby D, Johnson M and TF Freddo (2002). A new view of the

human trabecular meshwork using quick-freeze, deep-etch electron microscopy. Experimental

Eye Research 75(3):347-358 5YIF 2.91

J21. Sanchez JM, Li Y, Rubashkin A, Iserovich P, Wen Q, Ruberti JW, Kuang K, Diecke FPJ and

J Fischbarg (2002) Evidence for a central role for electro-osmosis in fluid transport by corneal

endothelium. Journal of Membrane Biology . 187(1):37-50 5YIF 2.48

J22. Ruberti JW and SD Klyce (2003) NaCl osmotic perturbation can modulate hydration control

in rabbit cornea. Experimental Eye Research 76(3): 349-359 5YIF 2.91

Curriculum Vitae Jeffrey W. Ruberti, August 2010

J23. Collier JH, Hu BH, Ruberti JW,Zhang J, Shum P, Thompson DH and PB Messersmith.

Thermally and photochemically triggered self-assembly of peptide hydrogels. Journal of the

American Chemical Society 123(38):9463-9464 (2001). 5YIF 8.26

J24. Overby D, Ruberti JW, Gong H, Freddo T and M Johnson. Specific Hydraulic Conductivity

of Corneal Stroma as Seen by Quick Freeze/Deep Etch. Journal of Biomechanical

Engineering. 2001 Apr;123(2):154-61. 5YIF 2.52

J25. Ruberti JW, Klyce SD, Smolek MK and M Caron. Anomalous Acute Inflammatory

Response in Rabbit Corneal Stroma. Investigational Ophthalmology and Visual Science

41(9) 2523-2530, 2000 5YIF 3.83

J26. Peattie RA, Asbury CL, Bluth EI and JW Ruberti. Steady Flow in Models of Abdominal

Aortic Aneurysms. Part I: Investigation of the Velocity Patterns. Journal of Ultrasound

Medicine, 15:679-688, 1996. 5YIF 1.39

J27. Asbury CL, Ruberti JW, Bluth EI and RA Peattie. Experimental Investigation of Steady Flow

in Rigid Models of Abdominal Aortic Aneurysms, Annals of Biomedical Eng ineering, 23: 29-

39, 1995. 5YIF 3.0

BOOK CHAPTERS

B1. Ruberti JW, Zieske JD and V. Trinkaus-Randall (2007). Corneal Tissue Replacement in

Principles of Tissue Engineering, 3rd edition. Eds Lanza R, Langer R and JP Vacanti,

Elsevier/Academic Press. Chapter 68 (24 pages)

B2. Ruberti, JW and SD Klyce (2002). Chapter 1: Physiological System Models of the Cornea in

Models of the Visual System. Hung, Eds: G.K. and K.J. Ciuffreda. Topics in Biomedical

Engineering International Book Series, Series Ed: Micheli-Tzanakou, E. Kluwer

Academic/Plenum Publishers, New York. pp. 3-55

REVIEW ARTICLES

R1. Ethier CR, Johnson M and JW Ruberti, Ocular Biomechanics and Biotransport. Invited review

for Annual Reviews of Biomedical Engineering 2004; 6:249-73. 5YIF 13.68

R2. **Ruberti JW and Roberts C (2010). Corneal Biomechanics and Biomaterials. Invited

review for Annual Reviews of Biomedical Engineering (2010). 5YIF 13.68. Article in

progress. Highest ranked journal in Biomedical Engineering.

MANUSCRIPTS IN A HIGH STATE OF PREPARATION *:

P1. Bhole A, Flynn B, Liles M and JW Ruberti (2009). Strain-protection of collagen from MMP-8

degradation.

P2. Flynn B, Bhole A, DiMarzio C and JW Ruberti (2009). Sub-resolution optical detection of

fibril diameter changes using DIC imaging.

P3. Zareian R, Patenaude J, Church K and JW Ruberti (2009). Design of two, low volume

bioreactors for enzyme mechanochemistry.

P4. Saeidi N and JW Ruberti (2009). Collagen fibril alignment in confining shear film.

P5. Saeidi N and JW Ruberti (2009). Mutability of collagen in assembled gels.

* IN HIGH STATE OF PREPARATION refers only to work in which all data have been collected and

manuscript preparation more than 50% finished.

Curriculum Vitae Jeffrey W. Ruberti, August 2010

CONFERENCE ABSTRACTS/PAPERS

C1. Ruberti J., Zareian R., Flynn B., Camp R. and A. Bhole (2010). Multiscale, experimental

investigations of collagen strain-enhanced stability. 6th World Congress of Biomechanics.

Singapore (Presentation).

C2. Camp RJ and JW Ruberti (2009) Mechanochemical assay for studying single type I collagen

monomers. BMES Fall 2009 OP10 -28C (Presentation)

C3. Zareian R, Saeidi N and JW Ruberti (2009). Strain-influenced degradation of native

collagenous tissue in a very low-volume, environmentally-controlled bioreactor. ASME IMECE

Fall 2009 (IMECE2009 -13084 Paper/Poster)

C4. Saeidi N, Sander E and JW Ruberti (2009). Real-time observation and quantification of shear-

induced collagen self-assembly. ASME Summer Bioengineering Conference #206773 (Mow

Symposium Talk)

C5. Patenaude JA, Ruberti JW, Desjarlais A, Kornfeld J, Lee M, McGrath M and J Perry (2009)

Design of optically accessible, ultra low-volume, tissue loading bioreactor. ASME Summer

Bioengineering Conference #206675 (poster)

C6. Flynn BP, Bhole A, DiMarzio C and JW Ruberti (2009) A novel, label-free method for

quantifying collagen fibril formation and degradation using DIC microscopy, electromagnetic

wave theory and image processing. ASME Summer Bioengineering Conference #206592

(poster)

C7. Saeidi N, Ren R, Guo XQ, Melotti SA, Hutcheon AEK, Zieske JD, Trinkaus-Randall V and

JW Ruberti (2009) Collagen stability in long-term 3-D culture systems for corneal stromal

tissue engineering. ARVO abstract; IOVS 50 (suppl), 2550 (Presentation)

C8. Ruberti JW and JB Sokoloff (2008) A potentially low-dissipation mechanism for load support

by articular cartilage. MRS Fall conference Boston 2008 (Presentation Z2.7)

C9. Portale K, Saeidi N, Kowalski G and JW Ruberti (2008). Design of a cell-free biomimetic

collagen printer or nanoloom. ASME IMECE Fall 2008 (Poster: IMECE2008 -66333)

C10. Zareian R and JW Ruberti (2008). Influence of mechanical load on enzymatic cleavage of

native collagen. ASME IMECE Fall 2008 (Poster/paper: IMECE200 8-68117)

C11. Saeidi N, Portale K and JW Ruberti (2008) Smart Molecules: Organization and morphology

of the self-assembled collagen fibrils formed from a solution of densely packed collagen

monomers. ASME Summer Bioengineering Conference (Poster-SBC2008-193025)

C12. Zareian R, Church K and JW Ruberti (2008) Influence of mechanical load on the

degradation of corneal collagen. ASME Summer Bioengineering Conference (Poster

SBC2008-193036)

C13. Saeidi N, Portale KN, Guo XQ, Melotti SA, Hutcheon AEK, Trinkaus-Randall V, Zieske JD

and JW Ruberti (2008). Atelo-collagen monomers encode the information necessary to

produce aligned collagen lamellae de novo. ARVO abstract; IOVS 49, 3921 (Poster)

C14. Hutcheon AEK, Ren R, Guo XQ, Melotti SA, Ruberti JW, Zieske JD and V. Trinkaus-

Randall. (2008) Glycosaminoglycans are present in long-term 3-D cultures of human corneal

fibroblasts. ARVO abstract, IOVS 49, 3919 (Poster)

C15. Ruberti JW, Melotti SA, Guo XQ, Saeidi N, Hutcheon AEK, Trinkaus-Randall V and JD

Zieske. (2008) Human corneal fibroblasts secrete locally-organized collagen arrays on

disorganized collagen substrates. ARVO abstract, IOVS 49, 3920 (Poster).

Curriculum Vitae Jeffrey W. Ruberti, August 2010

C16. Bueno-Hoyos EM, Saeidi N and JW Ruberti (2008) In vitro characterization of corneal

stromal fibroblast cell and matrix morphology in response to bovine serum and insulin-

transferrin-selenium. ARVO abstract, IOVS 49, 4041 (Presentation)

C17. Zareian R, Church KP and JW Ruberti (2008). Influence of mechanical load on the

degradation of corneal collagen. ASME Summer Bioengineering Conference (Poster)

C18. Bueno EM, Saeidi N and JW Ruberti (2008). Stratification is necessary for the secretion of

aligned collagen fibrils by corneal stromal fibroblasts in vitro. SPBRM (conf) Jan 9 -11.

(Presentation).

C19. Portale K, Saeidi N, Kowalski G, Nowak W and JW Ruberti (2007). Design of cell free

collagen printer or nanoloom. BMES Annual Fall Meeting Sept 26 -29 p3.157 (Poster)

C20. Ruberti JW, Guo XQ, Melotti SA, Hutcheon AE, Saeidi N, Trinkaus-Randall V and JD

Zieske (2007). Primary human corneal fibroblasts synthesize organized matrix on disorganized

collagen. BMES Annual Fall Meeting Sept 26 -29 p5.156 (Poster)

C21. Mundra A, Oliveira S, Church KP, Barabino G and JW Ruberti (2007). Design of

compression bioreactor for mechanical stimulation of native and engineered cartilage. BMES

Annual Fall Meeting Sept 26-29 p5.161 (Poster)

C22. Church KP and JW Ruberti (2007). Influence of mechanical load in the degradation kinetics

of collagen in native tissue. BMES Annual Fall Meeting Sept 26 -29 p5.149 (Poster)

C23. Saeidi N, Portale KN and JW Ruberti (2007). Organization and morphology of self-

assembled cholesterically dense collagen matrices. BMES Annual Fall Meeting Sept 26 -29

p4.158 (Poster)

C24. Bhole AP and JW Ruberti (2007) Strain stabilizes reconstituted collagen network during

fibrolysis. BMES Annual Fall Meeting Sept 26-29 p3.156 (Poster)

C25. Bueno EM, Saeidi N and JW Ruberti (2007). Live, long-term monitoring of in vitro matrix

synthesis and organization by bovine corneal fibroblasts. BMES Annual Fall Meeting Sept 26 -

29 p2.93 (Poster)

C26. Ruberti JW, Guo XQ, Melotti SA, Hutcheon AE, Trinkaus-Randall V and JD Zieske

(2007). Fibril organization and morphology in stromal constructs synthesized by primary

human corneal fibroblasts. IOVS 48 (suppl) #1867

C27. Saeidi N, Portale KN and JW Ruberti (2007). Direct optical and quick freeze deep etch

imaging of self-assembled, cholesterically dense collagen gels. IOVS 48 (suppl) #1865 (Poster)

C28. Bueno-Hoyos EM, Saeidi N and JW Ruberti (2007). Live, long-term monitoring of in vitro

matrix synthesis and organization by bovine corneal fibroblasts. IOVS 48 (suppl) #1499

(Poster)

C29. Hutcheon AE, Guo XQ, Ruberti JW and JD Zieske. (2007) Characterization of an in vitro

model of human corneal fibrosis. IOVS 48 (Suppl) #1490 (Poster)

C30. Saeidi N, Melotti SA and JW Ruberti. (2007) Dynamic observation of collagen assembly

and degradation. Society for Biomaterials. #351 (Poster)

C31. Ruberti JW, Guo X, Melotti SA, Hutcheon A, and JD Zieske. (2006) Evolution of cells and

collagen organization in tissue engineered corneal stromas. BMES Conference abstract 2006

(prg# 790) Chicago, IL

C32. Chitnis CV, Zareian R and JW Ruberti. (2006) Dynamic optical visualization of collagen

degradation. BMES conference abstract (prg# 1064) Chicago, IL

Curriculum Vitae Jeffrey W. Ruberti, August 2010

C33. Church KP, Cahill R, Jaworski B, and JW Ruberti. (2006) Miniature load and strain-

controlling bioreactor for direct observation of tissue remodeling. BMES conference abstract

(prg# 1073) Chicago, IL

C34. Bueno EM and JW Ruberti. (2006) Collagen transport through nanoporous track -etched

membranes. BMES conference abstract (prg# 1 237) Chicago, IL

C35. Ruberti JW and N Saeidi. Nucleation, growth and alignment of collagen fibrils produced by

shear-influenced self-assembly for corneal tissue engineering templates. (2006) World Congress

of Biomechanics (presentation) Munich, Germany

C36. Zieske JD, Guo XQ, Melotti SA, Hutcheon AE and JW Ruberti. (2006) Spatial

Organization of Engineered Corneal Stroma. Is there a need for contact guidance or direct

mechanical stimulus? World Congress of Biomechanics (Invited Talk) Munich, Germany

C37. Ruberti JW, Guo XQ, Melotti SA, Hutcheon AE and JD Zieske. (2006) Three dimensional

organization of cells and matrix in stromal constructs secreted by human primary corneal

fibroblasts. IOVS 47 (suppl) 3948 (poster) Ft. Lauderdale, FL

C38. Saeidi, N and JW Ruberti. (2006) Kinetics of tethered collagen assembly in shearing flow

assessed by dynamic optical imaging. IOVS 47 (suppl) 3949 (poster) Ft. Lauderdale, FL

C39. Huang JD, Ruberti JW, Dabholkar AS, Menco BM, Presley JB, Curcio CA and M Johnson

(2005). Ultrastructure of Age-Related changes in human Bruch s membrane as seen by Quick

Freeze Deep Etch (QFDE) IOVS 46 (suppl) (poster). Ft Lauderdale, FL

C40. Ruberti JW and Hallab NJ (2004). Smart Matrix: Mechanical load protects fibrillar collagen

against enzymatic degradation. BMES (poster) Philadelphia, PA

C41. Ruberti JW and Melotti SA (2004) Corneal and scleral collagens assessed by modulated

differential scanning calorimetry. IOVS 45 (suppl) 3827 (poster). Ft. Lauderdale, FL

C42. Zieske J, Guo XQ, Hutcheon AEK and Ruberti JW (2004) Alignment of human corneal

fibroblasts in vitro. IOVS 45 (suppl) 3933 (poster). Ft Lauderdale, FL

C43. Ruberti JW, Melotti SA and GJC Braithwaite (2003). Nanoscale engineering of type I

collagen to mimic the multiple layers of aligned lamellae in cornea. IOVS 44(4) S4218 (paper)

Ft. Lauderdale, FL

C44. Fishbarg J, Sanchez JM, Li YS, Rubashkin A, Iserovich P, Wen Q, Ruberti JW, Kuang KY,

Diecke FPJ (2003) Electro-osmosis in fluid transport by corneal endothelium. FASEB J. 17(5)

A901-A902 Part 2 (suppl).

C45. Bass EC, Wistrom EV, Diedrich CJ, Nau WH, Pellegrino R, Ruberti JW and JC Lotz. In situ

stresses inhibit thermal denaturation of annulus fibrosus. ISSLS abstract 2002

C46. Ruberti JW, Curcio CA, Millican L, Menco BPM, Huang JD and M Johnson (2002) An Age

Related Lipid Wall in Human Bruch s Membrane. [ARVO abstract] IOVS 43(4) S2785 2002

(poster). Ft. Lauderdale, FL

C47. Guo XQ, Hutcheon AEK, Ruberti JW and J.D. Zieske. Human Corneal Organotypic

Cultures Using Untransformed Cells. [ARVO abstract] IOVS 43(4) S3211 2002 (poster) Ft.

Lauderdale, FL

C48. Negahban K, Ruberti JW, Qui G and H Gong, Regional variation of corneal endothelial

density, implications for sampling in eye bank eyes. [ARVO abstract] IOVS 43(4) S3175 2002

(poster). Ft. Lauderdale, FL

C49. Ruberti JW, Curcio CA and M Johnson. Quick Freeze/Deep Etch (QFDE): A better imaging

method to extract micro-scale specific hydraulic conductivity (SHC) from Bruch s membrane.

[ARVO abstract] IOVS 42(4) S1204 2001 (poster) Ft. Lauderdale, FL

Curriculum Vitae Jeffrey W. Ruberti, August 2010

C50. Iserovich P, Sanchez JM, Li Y, Ruberti JW, Kuang K, Wen Q, and J. Fischbarg.

Electroosmotic fluid transport by corneal endothelium could provide a novel explanation for the

phenomenon of corneal volume regulation. [ARVO abstract] IOVS 42(4) S2700 2001 (poster).

Ft Lauderdale, FL

C51. Gong H, Overby D, Ruberti J, Freddo T and M Johnson. Human outflow pathway viewed by

quick freeze deep etch. [ARVO abstract] IOVS 42(4) S749 2001 (poster) Ft. Lauderdale, FL

C52. Karon MD, Klyce SD, Schilleci JT and JW Ruberti. Effect of inhibition of inflammatory

mediators on trauma induced stromal edema. [ARVO abstract] IOVS 42(4) S4846 2001

(poster) Ft. Lauderdale, FL

C53. Karon MD, Klyce SD, Schelleci JT and JW Ruberti. Corneal stromal swelling dynamics

after epithelial debridement. (ASME Bioengineering Conference 2001)

C54. Ruberti JW, Gong H, Freddo T F, Klyce SD and M Johnson, Macromolecular gradients in

corneal stroma [EMBS abstract]. Proceedings of BMES & EMBS Joint Conference 1:214 1999

(presentation)

C55. Johnson M, Overby D, Ruberti J, Freddo TF and H Gong. Hydrodynamics of aqueous humor

outflow. Proceedings of BMES & EMBS Joint Conference 1:215 1999 (presentation)

C56. Ruberti JW, Gong H, Freddo TF, Klyce SD and M Johnson, Outward flow may enhance

large mobile molecule concentration gradients in corneal stroma [ARVO abstract]. IOVS,

40(4):B397 1999 (Poster). Ft. Lauderdale, FL

C57. Klyce SD, Karon MD, Ruberti JW, Smolek MK and T Goto. Epithelial debridement initiates

acute anterior stromal edema [ARVO abstract]. IOVS, 40(4):1019 1999 (Presentation). Ft.

Lauderdale, FL

C58. Johnson M, Overby D, Ruberti JW, Freddo TF, and H Gong, Source of outflow resistance in

the normal human eye [ARVO abstract]. IOVS, 40(4):1042 1999 (Presentation). Ft.

Lauderdale, FL

C59. Ruberti JW and SD Klyce. Investigation of Corneal Endothelial Response to NaCl Osmotic

Perturbations [ARVO abstract]. IOVS, 39(4):S906 1998 (Presentation). Ft. Lauderdale, FL

C60. Klyce SD and JW Ruberti. Epithelial debridement alters stromal properties. Abstracts of

Aegean Cornea IV, June 26-28, 1998, Santorini Island, Greece. (Presentation)

C61. Ruberti JW and SD Klyce. Dynamics of the corneal stroma. (Invited) Exp Eye Res

67(S1):S206, 1998. (Presentation)

C62. Ruberti JW and SD Klyce. Evidence of Corneal Endothelial Membrane Permeability and

Transport Modulation by Osmotic Shock [ARVO abstract]. IOVS, 38(4):S683 1997

(Presentation). Ft Lauderdale, FL

C63. Ruberti JW and SD Klyce. A Computational Transport Model for Membrane Bound Soft

Tissue., Faseb Journal 11(3):A20 1997. (Presentation)

C64. Ruberti JW and SD Klyce. New Computational Model of Corneal Hydration Dynamics

[ARVO abstract]. IOVS, 37(3):S352 1996. (Poster) Ft. Lauderdale, FL

C65. Asbury CL, Ruberti J, Peattie RA and EI Bluth. (1993) Investigation of steady flow in rigid

models of abdominal aortic-aneurysms. A240 Part 1, Feb 19 .

INVITED CONFERENCE TALKS AND SYMPOSIA

C66. Ruberti JW (2008) New view of an old material: Collagen as an intelligent, self-organizing,

load-responsive structural building block. MRS Fall conference, Boston 2008. (Invited

Symposium DD1.8).

Curriculum Vitae Jeffrey W. Ruberti, August 2010

C67. Ruberti JW (2007) Collagen fibrillogenesis in vitro. IOVS 48 (Suppl.) #341. (Invited

symposium) ARVO annual conference, Ft. Lauderdale, FL

C68. Ruberti JW (2005) Fibrillar collagen (with its complement enzyme as a load-adaptive

smart engineering material. Implications of engineering of connective tissue. 25 th Biennial

Corneal Conference, Boston, MA (invited talk)

C69. Ruberti JW and Hallab NJ (2004). Mechanical load protects fibrillar collagen against

enzymatic degradation. 8th Cardiff Corneal Conference. Cardiff, UK. (invited talk paid

travel)

C70. Ruberti JW (1999). Detection and quantification of anomalous swelling response to

debridement in cornea. 21st Biennial Corneal Conference, Schepen s Eye Research Institute.

(invited talk)

INVITED NON-CONFERENCE TALKS (since 2004)

1. Forefront lecture Tissue Engineering Regenerative Medicine North America (TERMIS-NA)

and American Society for Matrix Biology (ASMB), Fall 2010 (paid travel)

2. Boston University, Department of Biomedical Engineering, Fall 2009

3. Devers Eye Institute, Portland Ore, Fall 2009 (paid travel)

4. Renssalaer Polytechnic Institute, Biomedical Engineering Dept. Fall 2009 (paid travel)

5. Northeastern University, Pharmaceutical Sciences Dept. Fall 2009

6. Brookhaven National Laboratory, National Synchrotron LS, Summer 2009 (paid travel)

7. Brandeis University, Physics Department, MRSEC lecture Spring 2009

8. Northeastern University, Physics Department, CIRCS lecture Fall 2008

9. University of Florida, Dept. Materials Engineering 2008 (paid travel)

10. UCLA, Department of Pathology, Spring 2008 (paid travel)

11. Tufts University, Department of Pathology, Fall 2007

12. Cardiff University, Department of Biophysics, Fall 2007 (paid travel)

13. Tufts University Department of Biomedical Engineering, Fall 2007

14. Lehigh University, Department of Mechanical Engineering, Fall 2006 (paid travel)

15. Northeastern University, Dept of Biology, Fall 2006

16. Harvard University, Schepen s Eye Research Institute, Fall 2006

17. Boston University, Department of Ophthalmology, Summer 2006

18. Harvard University, Center of Engineering in Medicine, Spring 2006

19. University of Minnesota, Department of Biomedical Engineering, Fall 2005 (paid travel)

20. Brown University Division of Engineering, Fall 2005

PATENTS

Patents issued

P1. Spiegelberg SH, Ruberti JW and GJC Braithwaite. System and methods for reducing

interfacial porosity in cements Pat No. 6,884,264. April 26, 20 05 (assignee Cambridge

Polymer Group)

P2. Braithwaite GJC and Ruberti JW. Layered aligned polymers and methods of making same.

Pat No. 7,048,963 May 23, 2006 (assignee Cambridge Polymer Group)

Curriculum Vitae Jeffrey W. Ruberti, August 2010

P3. Muratoglu OK, Spiegelberg SH, Ruberti JW and Abt Niels. PVA Hydrogel Pat. No.

7,235,592 June 26, 2007 (assignee Cambridge Polymer Group/Zimmer)

P4. Ruberti JW and GJC Braithwaite. Systems and methods for controlling and forming

polymer gels. Pat No. 7,485,670. February 3, 2009. (assignee Cambridge Polymer

Group).

Patent applications pending

P5. Family of patent extensions of Ruberti JW and GJC Braithwaite. System and methods of

controlling and forming polymer gels.

i. App# 200********. September 2, 2004 (assignee Cambridge Polymer Group)

ii. App# 200********. Jan 27, 2005 (assignee Cambridge Polymer Group)

iii. App# 200********. Nov 30, 2006 (assignee Cambridge Polymer Group)

iv. App# 200********. Mar 8, 2007 (assignee Cambridge Polymer Group)

v. App# 200********. July 19, 2007 (assignee Cambridge Polymer Group)

P6. Ruberti JW, Kowalski G, Burkey D. Nanoloom for controlling polymer assembly.

International App# PCT/US2006/037861 filed 09/27/2006 (Assignee Northeastern

University)

P7. Larson D, Ruberti JW, Slusarz J, Goulas N, Rush E, Ehret T. Systems, methods and

devices for frozen sample distribution. International App# PCT/US/001094 filed

01/16/2007. (assignees - Harvard University/Northeastern University)

P8. Saeidi N and Ruberti JW. Methods to produce organized collagenous arrays. (PCT

application filed April 14, 2009. (Assignee - Northeastern university)

Patents licensed

1. Ruberti JW and GJC Braithwaite. Systems and methods for controlling and forming

polymer gels. Pat No. 7,485,670. February 3, 2009. (assignee Cambridge Polymer

Group). This patent has been licensed to Hydrospine, Inc. for use in intervertebral disk

repair. It is the principal technology patent for the company.

2. Larson D, Ruberti JW, Slusarz J, Goulas N, Rush E, Ehret T. Systems, methods and

devices for frozen sample distribution. International App# PCT/US/001094. (assignees -

Harvard University/Northeastern University). This patent application has been licensed to

Cryoextract Instruments, LLC. Dr. Ruberti and his Capstone students are responsible for

the linear oscillating coring bit design.

THESIS

Ruberti, JW Theoretical and Computational Investigation of Corneal Hydration Dynamics. Ph.D.

Thesis. Department of Biomedical Engineering. Tulane University, New Orleans, LA 70112.

Co-Advisors: Professor Stephen D. Klyce (LSU Eye Center) and Professor David Rice (Tulane

University)

HONORS

2008 Soren Buus Outstanding Research Award, College of Engineering, Northeastern University

Produced Journal cover image for April 2003 IOVS (QFDE micrograph of macular lipids)

Tau Beta Pi (Engineering honor society) - inducted April 1993

Alpha Eta Mu Beta (Biomedical engineering honor society) - inducted April 1992

Curriculum Vitae Jeffrey W. Ruberti, August 2010

EXTERNAL FUNDING HISTORY

(Dr. Ruberti has not applied for internal funding to date )

Quick summary

Total Funding Secured Since Joining NEU: $3,631,000 (+ share of IGERT - $2,674,000)

Number of Applications submitted as PI:

NIH: 3-SBIR 2-R21 3-R01 (funded: 1-SBIR, 2-R21s and 1 R01)

NSF: 1-SGER (funded)

Efficiency as PI: 55%

Number of Applications supported by Professor Ruberti (not PI)

NSF: 8; NIH: 3; DOD: 1 TATRC subcontract

CURRENTLY FUNDED PROPOSALS

R01-EY015500 10/01/09-9/30/11

NIH/NEI $785,000 total cost

Engineering Biomimetic Corneal Constructs

The major goal of this project is investigate the processes responsible for the synthesis and organization

of extracellular matrix and utilize the information to control the synthesis of an in vitro corneal stroma.

Priority Score: 174 (19%)

Role: Principal Investigator Effort-15%

03/01/07 02/28/10

1R21EB007317 -01

NIBIB $420,000 total grant cost

Cell-free assembly of organized collagen arrays

The purpose of the study is to develop methods to produce organized 3 -dimensional arrays of collagen

fibrils on the benchtop de novo. The motivation for the study is provide an alternative to degradable

polymer scaffoldings for load-bearing tissue engineering.

Priority Score: 160 (4.6%)

Role: Principal Investigator Effort 15%

NSF 050433 10/012005-9/30/2010

NSF/NIH/NCI $2,674,233 total grant cost (funds not included in total funding secured for Dr. Ruberti)

IGERT Nanomedical Science and Technology

This is a training grant for interdisciplinary studies at the interface of nanotechnology and medicine.

Role: Co-Principal investigator (PI: Sri Sridhar Northeastern University)

PREVIOUSLY FUNDED PROPOSALS

R01-EY015500 2/01/05-9/30/09

NIH/NEI $1,750,000 total cost

Engineering Biomimetic Corneal Constructs

The major goal of this project is investigate the processes responsible for the synthesis and organization

Curriculum Vitae Jeffrey W. Ruberti, August 2010

of extracellular matrix and utilize the information to control the synthesis of an in vitro corneal stroma.

Priority Score: 174 (19%)

Role: Principal Investigator Effort-20%

TATRC FY05 SUB1 9/1/05-8/31/08

DOD $99,000 total costs for subcontract to NEU

Development of Anti-Inflammatory Corneal Bandage

The major goal of this project is to produce a scaffolding which may be used to support cells and

inflammatory mediators as part of an anti-inflammatory bandage for use on the battlefield.

Role: Co-investigator (PI: Dartt Schepen s Eye Research Institute) Effort-5%

09/01/06 08/31/08

1R21AR053551 -01

NIAMS/NIH $380,000 total costs

Investigation of collagen as a smart engineering material

The purpose of the study is to determine if collagen cleavage by MMPs is sensitive to the application of

mechanical force.

Priority Score: 165 (1.9%)

Role: Principal Investigator Effort: 15%

CMS-0541707 9/1/05-8/31/05

Source: NSF/CMS Total Costs $60,000

Development of a collagen nanoloom for the construction of 2 and 3 dimensional templates for tissue

engineering

The major goal of this project is to produce a bioinspired device capable of organizing collagen on the

nanoscale for use in tissue engineering.

Role: Principal Investigator

3 R01-EY015500-01A1S1 9/14/05

Source: NIH/NEI $140,000 total costs

Engineering Biomimetic Corneal Constructs

Supplement to R01 for the purpose of purchasing single molecule force magnetic trap.

Role: Principal Investigator

1 R43 YE14280 -01 Ruberti (PI) 08/01/2002-01/01/2003

Source: NIH/SBIR/Phase I $108,923 total costs

A Method to Generate Artificial Cornea Constructs

The primary focus of this grant is to generate arrays of aligned and uniform diameter collagen fibrils for

use as a surrogate corneal stroma.

Priority Score: 200

Role: Principal Investigator

NAS9-02011 Spiegelberg (PI) 03/01/2002-03/01/2003

Source: NASA/SBIR/Phase II

A Formation to Control and Constrain Water for Safe and Efficacious Microgravity Hygiene

Activities

Curriculum Vitae Jeffrey W. Ruberti, August 2010

The goal of this study is to develop a personal hygiene cleaning agent for use in a microgravity

environment.

Role: Co-Investigator

GRANT APPLICATIONS PENDING (in role of PI only)

1R01AR057056 -01A2

Investigation of collagen as a smart engineering material (submitted 02/01 /2009)

Agency: NIH

Amount Requested: ~$1,500,000

Examining the ability of mechanical force to direct the degradation and assembly kinetics of collagen

polymerization.

Original Priority Score: 250

Status: A revision of original proposal is currently underway

NSF #6928804

Collaborative research: Strain-engineered collagen microstructures

Agency: NSF (Physics of Living Systems)

Amount Requested: $330,000

Co-investigator: Markus Buehler (MIT)

APPLICATIONS NOT FUNDED (in role of PI only)

1RC1EB010864 -01 Constructing and growing organized, collagen-based matrices (submitted

05/01/2009)

Agency: NIH

Amount Requested: ~$1,000,000

Examining the ability of mechanical force to direct the degradation and assembly kinetics of collagen

polymerization.

Original Priority Score: Unscored (funding rate ~ 2%)

Status: One submission only permitted (challenge grant)

1R01AR057324 -01 Engineering Highly Organized Collagenous Matrix (submitted 05/20/2008)

Agency: NIH

Amount Requested: ~$2,300,000

Utilizing the liquid crystalline behavior of collagen to produce highly-organized collagenous matrix

similar to native load-bearing tissue.

Priority Score: Unscored

Status: Program announcement was discontinued. Grant has been modified and submitted as challenge

grant (see above).

1R43AR049960-01A1 Tunable hydrogel for intervertebral disc replacement (submitted 04/01/2003)

Agency: NIH

Amount Requested: ~$141,619

Development of a thetagel polyvinyl hydrogel for use as a nucleus pulposus replacement.

Curriculum Vitae Jeffrey W. Ruberti, August 2010

Priority Score: 198

Status: No revision submitted left industry

1R43AR051270 -01 Nanostructured gels for unicompartmental knee spacer (submitted 08/01/2003)

Agency: NIH

Amount Requested: ~$92,332

Tuning the mechanical properties of a novel thetagel polyvinyl hydrogel for potential use knee unispacer

for arthritis treatment.

Priority Score: 277

Status: No revision submitted left industry

TEACHING and ADVISING (all courses were regular load)

Course SGA Evaluation (criteria (low to high): 1-5)

Semester No. Credits Title Enrollment/ New* Learning** Instructor***

Respondents Comp/Overall

Fall 2004 MIM 702 4 Capstone 2 4/ N 5 5

Spring 2005 MIMU702 4 Capstone 2 6/6 N 4.83 4.83/4.83

Spring 2005 MIMU700 4 ME Research 1 N NA NA

Summer1 2005 MIMU701 1 Capstone 1 10 N NA NA

Summer1 2005 MTMG404 4 Ind Study 1 N NA NA

Summer 2 2005 MTMG404 4 Ind study 1 N NA NA

Fall 2005 MIMU702 4 Capstone 2 9/8 N 4.5 4.6/4.8

Fall 2005 MIMU701 1 Capstone 1 10/ N 2.35 3.65

Fall 2005 MTMG404 4 IND STUDY 1 N NA NA

Spring 2006 MIMU702 4 Capstone 2 5/4 N 4.3 4.8/4.0

Spring 2006 MIMU665 4 Musc Biomech 12/12 Y 3.8 4.1/4.4

Spring 2006 MTMG222 4 Musc Biomech 24/24 Y 3.8 4.1/4.4

Spring 2006 MIMU924 4 Dir Study 2 N NA NA

Summer1 2006 MIMU701 1 Capstone 1 15 N NA NA

Summer1 2005 MTMG404 4 Ind Study 1 N NA NA

Summer 2 2006 MIMU700 4 ME Research 1 N NA NA

Fall 2006 MIMU701 1 Capstone 1 15/10 N 4.1 4.0/4.0

Fall 2006 MTMG404 4 IND STUDY 1 N NA NA

Spring 2007 MIMU702 4 Capstone 2 5/5 N 4.4 3.2/3.8

Spring 2007 MIMU665 4 Musc Biomech 7/7 N 3.4 3.4/3.9

Spring 2007 MTMG222 4 Musc Biomech 6/5 N 4.6 4.8/4.8

Summer 2007 MTMG402 2 Ind Study 1 N NA NA

Summer 2007 MTMG404 4 Ind Study 1 N NA NA

Summer 2 2006 MIMU700 4 ME Research 1 N NA NA

Fall 2007 MIMU701 1 Capstone 1 9 N NA NA

Fall 2007 MIMU702 4 Capstone 2 6/6 N 4.2 4.2/4.8

Fall 2007 MTMG401 4 Ind Study 1 N NA NA

Fall 2007 MTMG404 4 Ind Study 1 N NA NA

Spring 2008 MIMU702 4 Capstone 2 5 N NA NA

Spring 2008 MIMU665 4 Musc Biomech 10/7 N 5.0 4.3

Curriculum Vitae Jeffrey W. Ruberti, August 2010

Spring 2008 MTMG222 4 Musc Biomech 16/11 N 3.8 4.4

Fall 2008 MIMU702 4 Capstone 2 15 N NA NA

Spring 2009 MIMU665 4 Musc Biomech 12/8 N 4.8 4.6

Spring 2009 MTMG222 4 Musc Biomech 7/4 N 4.3 4.8

UNDERGRADUATE RESEARCH ADVISING

Elias Moore Dept: Chemical Engineeering Start: Sept 2008

Activities: Single molecule investigation of collagen mechanochemistry

John Beale Dept: Chemical Engineeering Start: June 2009

Activities: Single molecule investigation of collagen mechanochemistry

GRADUATE ADVISING

Current Students:

Nima Saeidi Start: July 2005 Ph.D. Completed: August 2009

Thesis Title: Kinetics and control of collagen self-assembly

Ramin Zareian Start January 2006 Ph.D.

Thesis Title: Influence of mechanical load on the degradation of collagen monomers in native tissue

Robert Camp Start: January 2007 Ph.D.

Thesis Title: Quantifying the Mechanosensitivity of the Type I Collagen Monomer to Enzymatic

Cleavage

Jeff Patenaude Start: Sept 2008 Ph.D.

Thesis Title: Development of a collagen Nanoloom or Nanoprinter

Brendan Flynn Start: January 2008 Ph.D.

Thesis Title: Degradation and assembly dynamics of collagen under load

Graduated Students:

Kelli Church Completed May 2007 Masters

Thesis Title: Effect of tensile mechanical load on the degradation of native collagenous matrices

Anirudha Mundra Completed: May 2008 Masters

Thesis Title: Design of a Compression Bioreactor for the Mechanical Stimulation of Native and

Artificial Cartilage and the Study of Kinetics of Enzymatic Degradation of Collagen Fibrils in

Loaded Cartilage

Katie Portale Completed: May 2008 Masters

Thesis Title: Theoretical and Experimental Investigation of a Biomimetic Printer of Anisotropic

Arrays of Type I Collagen Fibrils or Nanoloom

Amit Bhole Completed: August 2008 Masters

Thesis Title: Strain Stabilizes Reconstituted Collagen Fibrillar Network Against Enzymatic

Cleavage by Collagenase.

POST-DOCTORAL ADVISING

Ericka Bueno, Ph.D. January 2006 February 2008

Project #1: Quantification of the transport of collagen through track -etched membranes

Project #2: Live dynamic differential interference contrast imaging of fibroblasts constructing matrix

Curriculum Vitae Jeffrey W. Ruberti, August 2010

Project #3: Culturing corneal fibroblastic cells for construct formation

Melody Liles, Ph.D. February 2008 January 2009

Project #1 Live dynamic differential interference contrast imaging of fibroblasts constructing matrix

Project #2 Attachment chemistry advising for single molecule enzymatic assays

PH.D. THESIS COMMITTEE MEMBERSHIP

Name Department Advisor Status

Ericka Bueno Chem Eng Prof. Barabino Graduated 2005

Jason Nikitczuk MIE Prof. Mavroidis Graduated 2007

Azadeh Khanicheh MIE Prof. Mavroidis Graduated 2007

Nicholas Yang MIE Prof. Nayeb-Hashemi Graduated 2009

Lin Wang Chem Eng Prof. Carrier In Progress

Reza Amini MIE Prof. Narusawa Graduated 2007

John Jagodnik MIE Prof. Muftu In Progress

Prashanth Makaram MIE Prof. Busnaina Graduated 2009

SERVICE/PROFESSIONAL DEVELOPMENT (EXTERNAL)

Conference Session Organizer

World Congress of Biomechanics, Session: Biomechanics and Cell and Tissue

Engineering of the Anterior Segment, Munich 2006

Conference Session Moderator

ARVO 2008, Session: Stroma and Keratocytes

ASME summer bioengineering conference 2008, Session: Soft Tissue Mechanics II

Review Panels

NIH: Ad Hoc/Conflict of interest Panel Reviewer for NIH/NEI R01/R03 (AED)

grants 2003

NIH: Ad Hoc/Conflict of interest Panel Reviewer for NIH/NEI R01/R03 (AED)

grants 2004

NIH: Ad Hoc/Conflict of interest Panel Reviewer for NIH/NEI R01/R03 (AED)

grants 2005

NSF CMS BioNano Panel Reviewer 20 05

NIH: Ad Hoc/Conflict of interest Panel Reviewer for NIH/NEI R01/R03 (AED)

grants 2006

NIH/NEI Visual Systems SBIR Panel Reviewer 2006

NIH/NEI Visual Systems SBIR Panel Reviewer 2007

NIH/NEI Visual Systems K99 Pathway Grant Reviewer 2007

NIH/NEI Anterior Eye Disease study section Ad Hoc Reviewer 2009

NIH RC1 RFA OD-09-003 Challenge Grants Panel #12

NIH RC1 RFA OD-09-003 Challenge Grants Panel #4

NIH: Ad Hoc/Conflict of interest Panel Reviewer for NIH/NEI R01/R03 (AED)

grants 2009

Journal Reviewing

Reviewer for Experimental Eye Research 1999-2009

Curriculum Vitae Jeffrey W. Ruberti, August 2010

Reviewer for Journal of Biomechanical Engineering 2007 -2008

Reviewer for IOVS 2001-2009

Reviewer for Annals of Biomedical Engineering 2005 -2008

Reviewer for Biophysical Journal 2006-2007

Reviewer for Cell Motility and the Cytoskeleton 2006-2007

Reviewer for Journal of Material Science 2007

Reviewer for Tissue Engineering 2006-2008

Reviewer for Ocular Surface 2006

Reviewer for Biomechanics and Modeling in Mechanobiology 2008 -2009

Reviewer for Acta Biomaterialia 2008

Reviewer for Frontiers in Bioscience 2008

Memberships

AAAS member 2002-present

BMES member 2000-present

ASME member 2004-present

Association for Research in Vision and Ophthalmology (ARVO) member

1996-present

SERVICE/PROFESSIONAL DEVELOPMENT (INTERNAL)

University

Patent Committee member 2005-present

College

Chairman: Committee to develop Ph.D. Program in Bioengineering: 2008-2009

Status: Program has begun fall 2009

Program Coordinator Ph.D. Program in Bioengineering: 2009-present

Member Chemical Engineering Search Faculty Committee: 2009 -present

Department

Faculty Searches

Member - Applied Mechanics: 2005-6

Member Applied Mechanics: 2006-7

Chair Biomedical Engineering: 2006-7

Seminar Series

Co-Chair Academic Years: 2006-8

Curriculum

Developed Minor in Biomedical Engineering (Biomechanics): 2005

Developed new course: Musculoskeletal Biomechanics: 2005



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