CURRICULUM VITAE
MARIANTHI G. IERAPETRITOU
Department of Chemical & Biochemical Engineering, RUTGERS UNIVERSITY
** ***** ****, **********, ****, NJ 08854-8058 USA
Tel: 848-***-****; Fax: 732-***-****; E-mail: abqjlh@r.postjobfree.com
URL: http://sol.rutgers.edu/staff/marianth
EDUCATION
1991-1995 Ph. D., Chemical Engineering Department, Imperial College, London, UK.
Faculty Advisor: Prof. Efstratios Pistikopoulos
Thesis Topic: "Optimization Approaches for Process Engineering Problems
under Uncertainty"
1986-1991 Diploma (Summa cum Laude), Chemical Engineering Department, NTUA,
Greece
Faculty Advisor: Prof. Z. Maroulis
Thesis Topic: "Synthesis of Heat Exchanger Network"
PROFESIONAL EXPERIENCE
2009- present Professor
Department of Chemical & Biochemical Engineering Rutgers University,
Piscataway, NJ
2004-2009 Associate Professor
Department of Chemical & Biochemical Engineering Rutgers University,
Piscataway, NJ
2005-2006 Visiting Associate Professor
Department of Chemical Engineering, MIT
Cambridge, MA
1998-2004 Assistant Professor
Department of Chemical & Biochemical Engineering Rutgers University,
Piscataway, NJ
1996-1998 Post Doctoral Research Associate
Department of Chemical Engineering, Princeton University, Princeton, NJ
Faculty Advisor: Prof. Christodoulos A. Floudas
1995-1996 Post Doctoral Research Associate
Center for Process Systems Engineering, Imperial College, London, UK
Faculty Advisor: Prof. Efstratios Pistikopoulos
RESEARCH INTERESTS
Computer-Aided Process and Product Design; Production Planning, Scheduling and Supply
Chain Management; Scheduling under Uncertainty; Uncertainty Considerations in Process
Design and Operations; Decomposition based Techniques for Complex Systems; Reaction
Model Reduction; Modeling and Optimization of Pharmaceutical Processes; Modeling and
Optimization of Liver Metabolism in Response to Stressors.
ACCOMPLISHEMTS
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HONORS AWARDS
2012 Outstanding Faculty Award, School of Engineering, Rutgers University
2004 Board of Trustees Research Award for Scholarly Excellence, Rutgers University
2001-2002 Teaching Excellence Award from Chemical Engineering Department, Rutgers
University
2000-2004 NSF CAREER Award, CTS 99-83406
1992-1994 Postgraduate Grant, Commission of European Community (ERB CHBI CT 93
0484)
1991-1992 Research/Teaching Fellowship, Imperial College
1986-1991 Undergraduate Fellowship, National Scholarship Foundation of Greece Award
1990-1991 Tiftixis Foundation Award, Athens Greece
1991 Economou Award for Academic Excellence, Athens, Greece
1991 Best Student of Chemical Engineering Department Award, National Technical
University of Athens
RESEARCH GRANTS
1. NSF Award 2012-2015 ($342,575) Integration of scheduling and control using closed loop
implementation (single PI)
2. NSF Award 2010-2013 ($343,901) Innovative methodologies for integrated planning and
scheduling and industrial applications (single PI)
3. Office of Naval Research 2010-2013 ($328,128) Modeling complexities in biofuel
combustion (PI, co-PI Ioannis Androulakis)
4. NSF Award 2009-2012 ($1,800,000) Commercializing of Continuous Pharmaceutical
Manufacturing Technology (PI, co-PI Fernando Muzzio, Gintaras Reklaitis, James Donald
Litster (Purdue), Raj Dave (NJIT),
5. NSF Graduate Research Supplement 2009-2010 ($53,938) (single PI)
6. NSF REU supplement 2009 ($12,000)
7. NSF Graduate Research Supplement 2008-2009 ($46,871) (single PI)
8. NIH Grant RO1 2008-2011 ($1,200,000) Bioinformatics Analysis of Control Mechanisms
of Hypermetabolism (co-PI with Ioannis Androulakis (PI), Charles Roth and Francois
Berthiaume)
9. NSF Award 2007-1010 ($316,317) Reactive Flow Simulation Using An Adaptive
Chemistry Framework (co-PI with Ioannis Androulakis (PI)).
10. NSF Award 2006-2009 ($399,572) Systematic Mathematical Strategies for Stochastic
Modeling and Uncertainty in Production Planning and Scheduling (single PI).
11. Office of Naval Research 2006-2009 ($270,782) Efficient Characterization of Combustion
Fuels (PI, co-PI Ioannis Androulakis)
12. National Center of Excellence for Environmental Bioinformatics and Computational
Toxicology EPA 2005-2010 ($4,500,000 ) (co-PI with William Welsh (PI), Panos
Georgopoulos, from Robert Wood Johnson Medical School, Ioannis Androulakis from
Rutgers University and Herschel Rabitz and Chris Floudas from Princeton University)
13. Metabolic Engineering National Science Foundation 2005-2008 ($998,659) Molecular
Network Controls of Hepatocyte Metabolism (co-PI with Charles Roth (PI), Martin
Yarmush and Ioannis Androulakis from Rutgers University)
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14. Quantitative Systems Biology National Science Foundation 2004-2007 ($500,000)
Experimental and Computational Studies to Optimize Hepatocyte Function (PI with
Charles Roth and Martin Yarmush from Rutgers University).
15. NSERC Strategic Grant 2004-2007 ($300,000) Innovative Approach to the Optimization
of Integrated Newsprint Mill Dynamic Operations (Co-PI with Professor Paul Stuart from
Ecole Polytechnique in Montreal).
16. Office of Naval Research 2003-2006 ($213,000) Development of an Adaptive Chemistry
Model for Combustion Systems Considering Micromixing Effects (single PI)
17. NSF Award 2002-2005 ($200,000) Design of Flexible Reaction Models (single PI)
18. CAREER NSF Award 2000-2004 ($308,803) Process Operations: Decision-Making under
Uncertainty (single PI).
19. Strategic Resource and Opportunity Analysis (SROA) ($80,000), Rutgers University The
Laboratory for Multiphase Reactive Flow (LMRF): Integrating Information Technology and
Experiments for Maintaining Technological Superiority in Homeland Security, Energy
Generation, and the Environment (Co-PI)
20. ACS-PRF Type G "Starter" Grant ($25,000) Incorporation of Uncertainty into Complex
Kinetic Mechanisms (single PI).
21. New Jersey Space Consortium Grant (NASA) ($25,000) Order Reduction of Complex
Kinetic Mechanisms Considering Micro-mixing Effects (single PI).
22. NSF International Division Grant, 0071505 ($13,800) Multiple Inputs - Multiple Outputs
(MIMO) Control Design (single PI).
23. Grant from BOC Gases ($43,000) to perform research on novel optimization approaches for
design under uncertainty.
24. Grant from Honeywell Hi-Spec Solutions ($25,000) to investigate the application of
continuous time formulation for refinery scheduling.
25. Grant for Union Carbide ($5,000) to study the optimization of Amerchol Plant operations.
26. Grant from Rutgers University (co-PI along with Professors Narashiman, Khinast, Glasser,
and Moghe) to modernize the graduate curricula in Chemical Engineering ($48,000).
27. Grant form Rutgers University (co-PI along with Professors Lehman, Norris, Denda, and
Buttner) to advance instructional technology for engineering education by introducing new
computer-based learning resources ($112,000).
28. Together with Professor Manish Parashar from Electrical Engineering Department lead the
Unisys initiative to establish one of the three Nationwide Excellence Centers equipped with
initial computing network ($278,000).
29. Grant from Rutgers University to initialize the research effort towards the application of
optimization methods in environmental treatment systems ($1,500).
30. Grant from Rutgers University to initialize the research effort towards the consideration of
uncertainty into complex kinetic models ($1,500).
31. Undergraduate Research Fellowship to support a student to do research in the area of
scheduling of batch processes ($1,500).
32. Undergraduate Research Fellowship to support a student to do research in the area of
refinery scheduling ($1,500).
TEACHING ACTIVITIES
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2010-2011 Chemical Analysis I Sophomore level course
2004-2008 Undergraduate Executive Officer
2004/2009 Freshmen Orientation Lectures
2004-2012 Process Dynamics and Control Senior level course
2004 Graduate level Elective Course: Modeling and Optimization of Process Design
and Operations
2000-2002 Design of Separation Processes - Senior Level Course:
2005-2007 Graduate level Core Course: Analytical Methods in Chemical and Biochemical
Engineering
2001-2002 Analytical Methods in Chemical and Biochemical Engineering - Graduate level
Core Course
1999-2000 Advanced Transport Phenomena - Graduate level Core Course:
1999 Process Systems Engineering - Graduate level Course
MENTORING GRADUATE & UNDERGRADUATE STUDENTS AND POSTDOCTORAL
SCHOLARS
Postdoctoral Scholars Supervised
Ravendra Singh (12/2011- Present)
Research Area: Process Integration and Control of Pharmaceutical Processes.
Jey Arjunan (10/2010 05/2011)
Research Area: Process Integration and Optimization of Pharmaceutical operations.
Vidya Iyer (06/2007 05/2010)
Research Area: Metabolic Engineering of Liver Cell Cultures
George Saharidis (03/2007- 12/2008)
Research Area: Decomposition Based Optimization of Complex Systems
Zhenya Jia (01/2007 02/2009)
Research Area: Modeling, Optimization and Control of Pharmaceutical Systems
Antoine Berton (03/2005 03/2006)
Research Area: Optimization and Control of Pulp and Paper Processes
cole Polytechnique. Montr al
Avinash Sirdeshpande (9/1999-3/2001)
Research Area: Reduction of Complex Kinetic Models
Current Affiliation: BOC Gases
Current Graduate Students Advised/Co-Advised
Nihar Sahay Since January 2012
Ph.D. expected 2016
Thesis Title Modeling of Sustainable Chemical Supply Chain
Zhaojia Lin Since September 2011
Ph.D. expected 2015
Thesis Title Modeling and Optimization of Chemical and Fuel production from
Biomass
Jinjun Zhuge Since January 2011
Ph.D. expected 2015
Thesis Title Integration of Production Scheduling and Control
Shuliang Zhang Since September 2009 (co-advised by Prof. I.P. Androulakis)
Ph.D. expected May 2014
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Thesis Title Modeling of Complex Reaction Systems
Nikisha Shah Since September 2008
Ph.D expected May 2013
Thesis Title Optimization of Supply Chain Management
Fani Boukouvala Since September 2008 (co-advised by Prof. F. Muzzio)
Ph.D expected May 2013
Thesis Title Modeling and Optimization of Pharmaceutical Processes
Past Graduate Students Advised/Co-Advised
Ph.D.
Yijie Gao Ph.D April 2012 (co-advised by Prof. F. Muzzio)
Thesis Title Modeling of Continuous Powder Mixing
Aditya Vanarase Ph.D. August 2011 co-advised by Prof. F. Muzzio)
Investigation of continuous mixing of powders
Mehmet Orman Ph.D December 2011 (co-advised by Prof. I.P. Androulakis)
Thesis Title Bioinformatics Analysis of Control Mechanisms of Burn and Sepsis
Induced Inflammatory Response
Kai He Ph.D. June 2010 (co-advised by Prof. I.P. Androulakis)
Thesis Title Development of Kinetic Model Reduction Framework and its
Application in Realistic Flow Simulation
Beverly Smith Ph.D. June 2010
Thesis Title Product Design and New Product Portfolio Management Modeled
Integration and Optimization
Zukui Li Ph.D. May 2010.
Thesis Title Process Operations with Uncertainty and Integration Considerations
Hong Yang Ph.D. December 2009 (co-advised by Prof. C.M.Roth)
Thesis Title: Design and analysis of Amino Acid supplementation in Hepatocyte
culture using in vitro experiment and mathematical modeling
Eddie Davis Ph.D. August 2008
Thesis Title: Modeling and Optimization of Process Engineering Problems
Containing Black-Box Systems and Noise
Patricia Portillo Ph.D. May 2008 (co-advised by Prof. F. Muzzio)
Thesis Title: Modeling, Control and Optimization of Continuous Pharmaceutical
Processes
Nripen Sharma Ph.D. January 2007. (co-advised by Prof. M.L.Yarmush)
Thesis Title: Metabolic Engineering of Stem Cell Differentiation
Tien Phong Huynh Masters October 2007 (co-advised by Prof. I.P. Androulakis)
Thesis Title Characterization of Complex Fuels for Combustion Applications
Zhenya Jia, Ph.D. September 2005.
Thesis Title: Uncertainty Analysis of Scheduling and Planning Problems.
Ipsita Banerjee Ph.D. May 2005.
Thesis Title: Multiscale Framework for Coupling Micromixing Phenomena and
Detailed Kinetic Networks for Combustion Systems in a Dynamic
Environment.
Dan Wu Ph.D. May 2005.
Thesis Title: Unified Frameworks for the Optimal Production Planning and
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Scheduling.
Vishal Goyal Ph.D. Jan 2005.
Thesis Title: Design and Synthesis of Flexible Module-Based Systems.
Aditya Bindal Ph.D. October 2004 (co-advised by Prof. J. Khinast)
Thesis Title: Optimization and Stability Analysis of Multidimensional Reacting
Systems
Masters
Amalia Nikolopoulou Masters December 2011
Thesis Title Hybrid Simulation Based Optimization for Supply Chain
Management
Steve Guzikowski Masters January 2008 (co-advised by Prof. C.M.Roth)
Thesis Title: Novel tools towards Improving Hepatocyte Function
Ian Glasgow Masters Dec 2005 (co-advised by Prof. P. Stuart Ecole
Polytechnique de Montreal, Montreal, Canada)
Thesis Title: Optimization Applications in Pulp Paper Process Industry
Suhrid Balakrishnan Masters September 2002 (Co-advised with Prof. P. Georgopoulos).
Thesis Title: Uncertainty considerations in Atmospheric Systems
Jeetmanyu Vin Masters July 2000
Thesis Title: Short Term Scheduling of Batch Plants under Uncertainty.
Member of PhD Committee
Qian Yang Ph.D. May 2012(Primary Advisor: Prof. I.P. Androulakis, CBE
Rutgers University)
Dynamics of Gene Expression Profiling in Liver Following Thermal
Injury and Sepsis
Alisa Vasilenko Ph.D. August 2011 (Primary Advisor: Prof. Muzzio, CBE Rutgers
University)
Rheological properties of granular materials
Eric Jayjock Ph.D. May 2011 (Primary Advisor: Prof. Muzzio, CBE Rutgers
University)
Advanced Data Inversion Applied to Cascade Impactor Design
Brenda Remy Ph.D. May 2010 (Primary Advisor: Prof. Glasser, CBE Rutgers
University)
Granular Flow, Segregation and Agglomeration in Bladed Mixers
Meric A. Ovacik Ph.D. May 2010 (Primary Advisor: Prof. Androulakis, BME Rutgers
University)
Modeling Pathways of Transcriptional Profiling of in Utero DBP
Exposure in Rat Testes
Kiran Vyakaranam Ph.D. May 2009 (Primary Advisor: Prof. Kokini, Food Science,
Rutgers University)
Thesis Title: Air Bubble Dynamics during Continuous Mixing of Viscous Liquids
Bharani Kumar
Ashokan Ph.D. October 2008 (Primary Advisor: Prof. Kokini, Food Science,
Rutgers University)
Thesis Title: Developing Methods for Design and Scale-up of Continuous Mixers
through 3D Numerical Simulation of Flow and Mixing
Marcos Llusa Ph.D. May 2008 (Primary Advisor: Prof. F. Muzzio)
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Thesis Title: Effect of shear mixing on the agglomeration of cohesive granular
material and the lubrication of granular blends
Jeng-Shiou Chen Ph.D. December 2007 (Primary Advisor: Prof. J. Khinast)
Thesis Title: Transition Metal Catalysts for Suzuki Couplings and Chiral
Hydrogenations: Kinetic Study, Computational Model and Synthesis
Paloma Pimenta Ph.D. June 2008 (Primary Advisor: Prof. H. Pedersen)
Thesis Title: Surfactant Solutions and Nanoparticle Suspensions
Thomas W Cochran Ph.D. June 2005 (Primary Advisor: Prof. Y. Chiew)
Thesis Title: Molecular Thermodynamic Modeling of Amorphous Solid Phase of
Chain Molecules
Xue Liu Ph.D. January 2005 (Primary Advisor: Prof. B. Glasser)
Thesis Title: Instability and Segregation in Bounded Gas-Particle Fluidized beds
Athanas Koynov Ph.D. May 2005 (Primary Advisor: Prof. J. Khinast).
Thesis Title: Computational Studies of Bubble Columns
Qinghua Wang Ph.D. September 2002 (Mechanical Engineering Department,
Rutgers
University, Primary Advisor: Prof. Y. Jaluria).
Thesis Title: Instability and Heat Transfer in Mixed Convection Flow in a
Horizontal Duct with Application to Cooling of Electronic Systems
Joe Kukura II Ph.D. July 2003 (Primary Advisor: Prof. F. Muzzio).
Thesis Title: Computational Investigation of Laminar Mixing in Pharmaceutical
Tanks
Christine Switzer Ph.D. May 2003 (Primary Advisor: Prof. D. Kosson).
Thesis Title: Soil Vapor Extraction and Air Sparging Remediation of
Trichlorethylene Contamination at the Savannah River Site
Elizabeth Shen Ph.D. 2001 (Primary Advisor: Prof. B. Narasimhan).
Thesis Title: Microphase Separation in Bioerodible Polyanhydrides for
Controlled Drug Release
Tongdan Jin Ph.D. 2001 (Industrial Engineering Department, Rutgers
University, Primary Advisor: Prof. D. Coit).
Thesis Title: System Reliability Assessment and Optimization Considering
Estimation Uncertainty
Stephano Cerbelli Ph.D. 2000 (Primary Advisor:Prof. F. Muzzio).
Thesis Title: The Topology of Mixing Structures in two-dimensional Periodic
and Aperiodic Chaotic Flows
Undergraduate Students Advised
Chaitali Inamdar, Uncertainty propagation in pharmaceutical modeling, Spring 2012-Summer
2012.
Jonathan E. Gajda, Segregation studies in continuous mixing, Summer 2012.
Lukasz Mioduszewski, Modeling of Pharmaceutical Processes. Fall 2010-Spring 2011.
Catherine Polyakov, Analyzing flux data for liver exposure to toxicants. Summer 2010.
Chris Doe, Studying hepatotoxicity due to environmental toxicants. Summer 2009, Fall 2009.
Nikisha Shah, Centralized Decentralized Optimization for Refinery Scheduling, Slade
Scholar honor student, Fall 2007- Spring 2008.
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Roentgen Hau, Examining the Content Uniformity of Powder Blends Using Near-Infrared
Spectroscopy, Slade Scholar honor student, Fall 2007-Spring 2008.
Lily Cheung Chang, Cell Growth and Urea Production in Hepg2 Cells under Different Insulin
and Glucose Concentration in the Media, Slade Scholar honor student, Fall 2007-Spring 2008
Sarah Abdelsayed, Optimization of supplementation for hepatocyte utilization in Bioartificial
liver devices, Fall 2007.
Timothy Lin, Understanding of acetaminophen (APAP) metabolism and induced-
hepatotoxicity, Fall 2005 Spring 2006
Adebola Ogunniyi, Development of Response Surfaces for Optimization of Noisy Black-Box
Systems, Fall 2004-Spring 2005
Yuliana Lugo, Application of MATLAB s model predictive control toolbox to mixing
processes, Summer 2006, RISE student.
Fred Bidrawn, Sensitivity analysis for Mixed Integer Linear Programming problems, Fall 2004.
Victor Low, Reduction of combustion chemistry, Spring- Summer 2007.
Salah Issa, Investigating the performance of hepatocyte cultures, Fall 2005- Spring 2006.
Enrique Coronado, Short-term Scheduling of Pharmaceutical Plants, Fall 2002.
Kimberly Ward, Design of a Graphical Interface for Scheduling of Batch Plants, Fall 2000,
Spring 2001.
Melissa Gregory, Integrating Energy Price Forecasting with Design Optimization of Energy
Intensive Plants, Spring 2001.
Regina Galie, Scheduling of Refinery Operations, Fall 2001.
Miral Parikh Design and Optimization of Air Separation Plant, SUPER Douglass College of
women Student, Spring 2001
Rinku Parikh, Model Reduction of Complex Kinetic Networks, Slade Scholar honor student-
Fall 2000 Spring 2002.
Claire Pinto, Short-term Scheduling of Multi-Product Batch Plants, Spring 2000.
Nisha Batra, Uncertainty Considerations In Atmospheric Kinetic Modeling, Spring 1999.
Pauline Voung, Flexibility Evaluation of Batch Processes. Fall 1998.
Grace Zougheib, Modeling of Short-term Scheduling of Batch Plants, Fall 1998.
UNIVERSITY SERVICE
Chair of the Committee on Appointments and Promotions 2010-2011
Committee on Appointments and Promotions 2009-2010
Faculty Secretary, SOE 2009-2011
Dean s Advising Committee 2009-2011
Member of New Brunswick Faculty Council 2011-2012
Faculty Admissions Committee 2009-2012
Undergraduate Executive Officer 2004-2008
Advisor Society of Women Engineers 2007-2008
Member of School of Engineering Rules of Procedure Committee 2003-2004
Chair of Graduate Admissions Committee 2001-2002
All Class Advisor 2000-2008
Departmental Web Site Coordinator 2000-present
Member of RUTCOR (Rutgers Center of Operations Research) 2000-present
Participation in program SUPER of Douglass College of women.
Chair, School of Engineering Student Discipline Committee 2000-present
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Member of the Departmental Admissions and Recruiting Committee 1998-2004
Member of the Departmental Qualifying Committee 1998-1999
Member of the Departmental Computing Committee 1998-1999
Member of the Departmental Promotional Material Committee 1998-1999
Junior Advisor 1999-2000
PROFESSIONAL ACTIVITIES
Conference Organizer
FOCAPO (Foundations of Computer Aided Process Operations) Conference, 2008
Membership in Professional Societies
Elected AIChE Computing and Systems Technology (CAST) director 2008-2010
Elected as a Trustee of the CACHE, the leading organization within the Chemical Engineering
community promoting computational applications
Member of American Institute of Chemical Engineers (AIChE)
Member of Institute of Operations Research and Management Sciences (INFORMS)
Member of Society of Industrial and Applied Mathematics (SIAM)
AIChE Computing and Systems Technology (CAST) Nominated and elected 10a (Systems and
Process Design) Division Director for 2006
Conference Organizing Committees
Organizing Committee: ESCAPE 16, ESCAPE 17, PSE 2006, ESCAPE 18, ESCAPE 21,
Annual Meeting of Creek Chemical Engineers, PSE 2009, FOCAPD 2009,
FOCAPO/CPC2012.
Chairing on Technical Meetings
Optimization I, European Symposium of Computer Aided Process Engineering (ESCAPE) 21,
Greece, June 2011 (Chair)
Supply Chain and Logistics Optimization AIChE Meeting, November 2007, Salt Lake City, UT
(Chair)
Design Analysis and Operations Under Uncertainty, AIChE Meeting, November 2007, Salt
Lake City, UT (Chair)
Planning and Scheduling, AIChE Meeting, November 2007, Salt Lake City, UT (co Chair)
Uncertainty in Process Design and Operations AIChE Meeting, November 2006, San
Francisco, CA (Chair).
Advances in Optimization I &II AIChE Annual Meeting, November 2005, Cincinnati, OH
(Chair).
Process Design and Operation Under Uncertainty, AIChE Annual Meeting, November
2005,Cincinnati, OH (Chair).
Computing Methods for CAPE, ESCAPE 15, May 2005, Barcelona, Spain (Chair).
Supply Chain Management I, AIChE Annual Meeting, November 2004, Austin, TX (Vise-
Chair).
Supply Chain Management II, AIChE Annual Meeting, November 2004, Austin, TX (Vise-
Chair).
Chair for Enabling Technologies in Product and Process Design: Operations, FOCAPD,
Princeton, NJ, July 2004
Manufacturing and Process Operations, ESCAPE 14, Lisbon, May 2004 (Chair)
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Enterprise Wide Optimization, AIChE Annual Meeting, November 2003, San Francisco, CA
(Chair).
Modeling and Computation for Process Design, AIChE Annual Meeting, November 2002,
Indianapolis, NV (Vice Chair).
Planning and Scheduling, AIChE Annual Meeting, November 2002, Indianapolis, NV (Vice
Chair).
Flexibility and Operability in Design, AIChE Annual Meeting, November 2001, Reno, NV
(Chair).
Applications of System Analysis Tools in Information Processing, AIChE Annual Meeting,
November 2001, Reno, NV (Vice Chair).
Applications of Scheduling and Planning in Batch Processes, AIChE Annual Meeting,
November 2001, Reno, NV (Chair).
Process Operations, 7th International Symposium on Process Systems Engineering (PSE) 2000,
Collorado (Chair).
Planning and Scheduling AIChE Annual Meeting, November 2000, Los Angeles, CA (Chair).
Design of Reactive Separation Systems, AIChE Annual Meeting, November 2000, Los
Angeles, CA (Chair).
Planning, Scheduling and Supply Chain Management, AIChE Annual Meeting, November
1999, Dallas, TX (Chair)
Batch Processing, AIChE Annual Meeting, November 1998, Miami Beach, FL (Chair).
Flexibility in Process Operations, AIChE Annual Meeting, November 1998, Miami Beach, FL
(Chair).
Design for Flexibility and Operability, AIChE Annual Meeting, Miami Beach, Nov 1998
(Chair).
COLLABORATIONS
Rutgers University
Professor Georgopoulos: in the area of sensitivity and uncertainty analysis in contaminant
source-to-dose sequence.
Professor Boros from Rutgers Center of Operations Research (RUTCOR) in the area of
introducing optimization theory in engineering.
Professor Coit from the department of Industrial Engineering in the area of Multiobjective
optimization of process operations under uncertainty
Professor Roth from Chemical and Biochemical Engineering and Biomedical engineering
departments in the area of hepatocyte functionality optimization.
Professor Androulakis from Biomedical engineering in the area of modeling regulatory
networks.
Professor Yarmush from Biomedical Engineering: co-advise of one PhD thesis in the area
of modeling and optimization of metabolic networks.
External
Professor Michel Minoux from University of Paris 6 in decomposition based methods.
Professor Anna Soffia Hauksdottir from University of Iceland a pioneer in the process
control field.
Professor Paul Stuart from Ecole Polytechnic in Montreal Canada in the area of
optimization in pulp and paper industry.
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Professor Yannis Kevrekides from Princeton University, in the area of optimization of
multiscale dynamic systems.
Dr Jeff Kelly Honeywell Hi-Spec Solutions in the area of refinery scheduling.
Dr Kevin Furman from ExxonMobil Research Engineering, in the area of supply chain
modeling and optimization.
Dr John Farell from ExxonMobil Research Engineering, in the area reduction of complex
reaction networks.
REFEREEING/REVIEWING ACTIVITY
Associate Editor
Journal of Natural Gas Science and Engineering Elsevier
Scientific Conference Reviewer
European Symposium of Computer Aided Process Engineering (ESCAPE)- 22 (2012)
European Symposium of Computer Aided Process Engineering (ESCAPE)- 21 (2011)
Process Systems Engineering International Meeting PSE 2009
Foundations of Computer Aided Process Design FOCAPD 2009
17th IFAC World Conference 2008
ACC (American Control Conference) 2006 Conference
8th International Symposium on Dynamics and Control of Process Systems (DYCOPS 2007)
ADCHEM (Advanced Control of Chemical Processes) Conference 2006
European Symposium of Computer Aided Process Engineering (ESCAPE)-16 / Process
Systems Engineering (PSE 2006)
Foundations of Computer Aided process Operations 2003 (FOCAPO)
European Symposium of Computer Aided Process Engineering (ESCAPE)- 6 (1996)
Scientific Journal Reviewer
Chemical Engineering Research and Design
Engineering Optimization
Computers and Chemical Engineering
AIChE Journal
Industrial Engineering & Chemistry Research
Energy and Fuels
Combustion and Flame
Optimization and Engineering,
Chemical Engineering Communications
Chemical Engineering Science
European Journal of Operations Research
Computers and Industrial Engineering
Applied Mathematical Modeling
European Journal of Operations Research
Biotechnology and Bioengineering
Metabolic Engineering
Journal of Zhejiang University SCIENCE (JZUS)
The International Journal
Discrete Event Dynamic System
IEEE Transactions on Dielectrics and Electrical Insulation
Proposal Reviewer
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National Science Foundation
National Science Foundation CAREER Panel, ITR Panel, EFRI Panel, CDI Panel, IGERT
Panel
Petroleum Research Fund (ACS).
FEATURED WORK
Spotlight feature Biotechnology and Bioengineering Effects of glucose and insulin on HepG2-
C3A cell metabolism, 2010.
Chemical Engineering Progress "Simplifying Kinetic Models" 97:11, 16, November 2001.
CITATIONS- IMPACT
No of citations: 1702; h-index 20 (source: Web of Science: Science Citation Index)
BOOKS AUTHORSHIP
M.G Ierapetritou, M. Minoux, G. Saharidis. Review of Decomposition Algorithms:
Applications to Large Scale Engineering problems. In preparation.
REFEREED JOURNAL PUBLICATIONS AND BOOK CHAPTERS
1. Mattick, J.,Yang, Q.,Orman, M., Ierapetritou, M.G., Berthiaume, F., Androulakis,
I.P.Long-term gene expression profile dynamics following cecal ligation and puncture in
the rat. Journal of Surgical Research, Available online,
http://dx.doi.org/10.1016/j.jss.2012.03.052.
2. Shah, N.K., Ierapetritou, M.G. Integrated production planning and scheduling
optimization of multisite, multiproduct process industry. Computers and Chemical
Engineering. 37, 214, 2012.
3. He, K., Ierapetritou, M.G., Androulakis, I.P. Exploring Flux Representations of Complex
Kinetics Networks. AICHE Journal. 58(2), 553, 2012.
4. Zhang, S., Broadbelt, L., Androulakis, I.P., Ierapetritou, M.G. Comparison of Biodiesel
Performance Based on HCCI Engine Simulation Using Detailed Mechanism with On-the-
fly Reduction. Energy and Fuels. 25(2), 976, 2012.
5. Orman, M.A., Mattick, J., Androulakis, I.P., Berthiaume,F., Ierapetritou, M.G.
Stoichiometry based steady-state hepatic flux analysis: Computational and experimental
aspects. Metabolites. 2(1), 268, 2012.
6. Boukouvala, F., Dubey, A.,Vanarase, A.,Muzzio F.,Ierapetritou, M.G. Computational
approaches for studying the granular dynamics of continuous blending processes,2-
Population balance and data-based methods. Macromolecular Materials and Eng. 297(1),
9, 2012.
7. Li, Z., and M.G. Ierapetritou Capacity expansion planning through augmented Lagrangian
optimization and scenario decomposition. AIChE Journal, 58, 871, 2012.
8. Orman, M.A.,Androulakis, I.P., Berthiaume,F., Ierapetritou, M.G. Metabolic network
analysis of perfused livers under fed and fasted states: Incorporating thermodynamic and
futile-cycle-associated regulatory constraints. Journal of Theoretical Biology. 293, 101,
2012.
9. Boukouvala, F., Ierapetritou, M.G. Feasibility analysis of black-box processes using an
adaptive sampling kriging-based method. Computers and Chemical Engineering. 36,358,
2012.
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10. Dubey, A.,Boukouvala, F.,Keyvan, G.,Hsia, R.,Saranteas, K.,Brone, D.,Misra,
T.,Ierapetritou, M.,Muzzio, F. Improvement of Tablet Coating Uniformity Using a
Quality by Design Approach. AAPS PharmSciTech, Available online, Doi:
10.1208/s12249-011-9723-xm 2012.
11. Orman, M.A., Berthiaume, F., Androulakis, I.P., Ierapetritou, M.G. Advanced
Stoichiometric Analysis of Metabolic Networks of Mammalian Systems. Critical Reviews
in Biomedical Engineering. 39(6), 511, 2011.
12. Ramachandran,R., Arjunan, J., Chaudhury, A., Ierapetritou, M.G. Model-Based control
loop performance assessment of a continuous direct compaction pharmaceutical process.
J. Pharm. Innov. 6, 249, 2011.
13. Nikolopoulou, A., Ierapetritou, M.G. Integration of operation planning and scheduling in
supply chain systems: a review. Chapter 1, In: Scheduling problems and solutions, Nova
Science Publishers, 2011.
14. Yang, Q.,Orman, M.A., Ierapetritou, M.G., Berthiaume,F., Androulakis I.P. Dynamics of
short-term gene expression profiling in liver following thermal injury. J. Surg. Res.,
Available online, doi:10.1016/j.jss.2011.09.052.
15. Orman, M.A.,Ierapetritou, M.G., Berthiaume,F., Androulakis I.P. The dynamics of the
early inflammatory response in double-hit burn and sepsis animal models. Cytokine.
56(2), 494, 2011.
16. Orman, M.A., Nguyen, T.T., Ierapetritou, M.G., Berthiaume,F., Androulakis I.P.
Comparison of the cytokine and chemokine dynamics of the early inflammatory response
in models of burn injury and infection. Cytokine. 55, 362, 2011.
17. Orman, M.A.,Ierapetritou, M.G.,Androulakis I.P., Berthiaume,F. Metabolic response of
perfused livers to various oxygenation conditions. Biotechnology and Bioengineering.
108(12), 2947, 2011.
18. Smith,B., Ierapetritou, M.G. Modeling and optimization of product design and portofolio
management interface. Computers and Chemical Engineering. 35, 2579, 2011.
19. He, K., I.P. Androulakis, M.G. Ierapetritou. Numerical Investigation of Homogeneous
Charge Compression Ignition (HCCI) Combustion with Detailed Chemical Kinetics
Using On-the-Fly Reduction. Energy and Fuels. 25(8), 3369, 2011.
20. Smith,B., Ierapetritou, M.G. Sensitivity-Based product portofolio and design integration.
Industrial Eng. & Chem. Research 50, 3919, 2011.
21. Dubey, A.,Sarkar, A., Ierapetritou, M.G.,Muzzio F.et al. Computational approaches for
studying the granular dynamics of continuous blending processes,1- Dem based methods.
Macromolecular Materials and Eng. 296, 290, 2011.
22. Yang, H., Ierapetritou, M.G., Roth C.M. Analysis of Amino Acid Supplementation
Effects on Hepatocyte Cultures Using Flux Balance Analysis. OMICS: A Journal of
Integrative Biology. 15, 449, 2011.
23. Ovacik, M.A.,Sen, B., Euling S.Y., Gaido, K.W., Ierapetritou, M.G., Androulakis
I.P.Pathway modeling of microarray data: A case study of pathway activity changes in the
testis following in utero exposure to dibutyl phthalate (DBP). Toxicology and Applied
Pharmacology, In Press, doi:10.1016/j.taap.2010.09.008
24. Orman, M.A., Berthiaume,F.,Androulakis I.P., Ierapetritou, M.G. Pathway analysis of
liver metabolism under stressed condition. Journal of Theoretical Biology 272, 131, 2011.
25. Shah, N., Li, Z., and M.G. Ierapetritou Petroleum refining operations: key issues,
advances and opportunities. Ind. Eng. Chem. Res. 50, 1161, 2011.
13
26. Gao Y.,Vanarase A.U., Muzzio F., Ierapetritou M.G. Characterizing continuous powder
mixing using residence time distribution. Chemical Engineering Science. 66, 417, 2011.
27. Saharidis, G., Androulakis, I., and Ierapetritou, M.G. Model Building Using Bi-level
Optimization. Journal of Global Optimization. 49, 49, 2011.
28. Shah,N.and M.G. Ierapetritou Short-term scheduling of a large-scale refinery operations:
incorporating logistics. AIChE Journal, 57(6), 1570, 2011.
29. Gao Y., Muzzio F., Ierapetritou M.G. Characterization of feeder effects on continuous
solid mixing using Fourier series analysis. AIChE Journal, 57(5), 1144, 2011.
30. Orman, M.A., Arai, K., Yarmush, M.L., Androulakis, I.P., Berthiaume,F., Ierapetritou,
M.G.Metabolic flux determination in perfused livers by mass balance analysis: Effect of
fasting. Biotechnology and Bioengineering, 107, 1097, 2010.
31. He, K., I.P. Androulakis, M.G. Ierapetritou. Incorporation of Detailed Chemical
Mechanisms in Reactive Flow Simulations Using Element-Flux Analysis. Ind. Eng.
Chem. Res. 49 10471, 2010.
32. Portillo, P.M., Vanarase A.U., Ingram A., Seville J.K., Ierapetritou, M.G., Muzzio, F.J.
Investigation of the effect of impeller rotation rate, powder flow rate, and cohesion on
powder flow behavior in a continuous blender using PEPT. Chemical Engineering
Science, 65, 5658, 2010.
33. Iyer, V.V., Ovacik, M.A., Androulakis, I.P., Roth, C.M., Ierapetritou,
M.G.Transcriptional and metabolic flux profiling of triadimefon effects on cultured
hepatocytes. Toxicology and Applied Pharmacology, 248, 165, 2010.
34. Boukouvala, F., Muzzio, F.J., and Ierapetritou, M.G. Design Space of pharmaceutical
processes using data-driven-based methods. Journal of Pharmaceutical Innovation, 5,
119, 2010.
35. Yang, H., Ierapetritou, M.G., Roth C.M. Effects of amino acid transport limitations on
cultured hepatocytes. Biophysical Chemistry, 152, 89, 2010.
36. Li, Z., and M.G. Ierapetritou Rolling horizon based planning and scheduling integration
with production capacity consideration. Chem. Eng. Science, 65, 5887, 2010.
37. Saharidis, G., and M.G. Ierapetritou. Improving benders decomposition using maximum
feasible subsystem (MFS) cut generation strategy. Comp. Chem. Eng., 34, 1237, 2010.
38. He, K., M.G. Ierapetritou, I.P. Androulakis Integration of on-the-fly kinetic reduction
with multidimensional CFD. AIChE J., 56 1305, 2010.
39. Iyer, V.V., Yang, H., Ierapetritou, M.G., Roth C.M. Effects of Glucose and Insulin Level
on HepG2-C3A Cell Metabolism. Biotechnology and Bioengineering, 107, 347, 2010.
40. Boukouvala, F., Muzzio, F.J., and Ierapetritou, M.G. Predictive Modeling of
Pharmaceutical Processes with Missing and Noisy Data. AIChE Journal, 56, 2860, 2010.
41. Smith, B., and M.G. Ierapetritou. Integrative Chemical Product Design Strategies:
Reflecting Industry Trends and Challenges. Comp. Chem. Eng. 34, 857, 2010.
42. Li, Z., and M.G. Ierapetritou Production planning and scheduling integration through
augmented Lagrangian optimization. Comp. Chem. Eng. 34, 996, 2010.
43. Saharidis, G. K. D., M. Minoux, M. G. Ierapetritou.Accelerating Bender's method using
covering cut bundle generation. Intl. Trans. in Op. Res., 17, 221, 2010.
44. Davis, E., and M.G. Ierapetritou. A Centroid-Based Sampling Strategy for Kriging Global
Modeling and Optimization. AIChE J. 56, 220, 2010.
14
45. Saharidis, G. K. D., M. M. Golias, M. Boile, S. Theofanis, M. G. Ierapetritou.The berth
scheduling problem with customer differentiation: a new methodological approach based
on hierarchical optimization. Int J Adv Manuf Technol, 46, 377, 2010.
46. He, K., I.P. Androulakis, and M.G. Ierapetritou. Multi-element Flux Analysis for the
Incorporation of Detailed Kinetic Mechanisms in Reactive Simulations. Energy Fuels, 24,
309, 2010.
47. He, K., I.P. Androulakis, and M.G. Ierapetritou. On-the-fly reduction of kinetic
mechanisms using element flux analysis. Chem. Eng. Sci., 65, 1173, 2010.
48. Ierapetritou M.G., P.G. Georgopoulos, C.M. Roth, I.P. Androulakis. Tissue-Level
Modeling of Xenobiotic Metabolism in Liver: An Emerging Tool for Enabling Clinical
Translational Research. Cts-Clinical and Translational Science, 2, 228, 2009.
49. Jia, Z., E.Davis, F. Muzzio, and M.G. Ierapetritou. Predictive Modeling for
Pharmaceutical Processes using Kriging and Response Surface. Jl. Pharm. Innov., 4, 174,
2009.
50. Saharidis, G., and M.G. Ierapetritou. Scheduling of Loading and Unloading of Crude oil
in a refinery with combine mixture preparation. Ind. Eng. Chem. Res., 48, 2624, 2009.
51. Yang, H., and M.G. Ierapetritou. A Rational Design Approach for Amino Acid
Supplementation in Hepatocyte Culture. Biotechnology and Bioengineering. 103, 1176,
2009.
52. Lima, F.V., Z. Jia, M.G. Ierapetritou and C. Georgakis Similarities and Differences
between the Concepts of Operability and Flexibility. AIChE J., 56, 702, 2009.
53. Golias, M.M., Saharidis, G.K., Boile, M., Theofanis, S., Ierapetritou, M.G. The berth
allocation problem: Optimizing vessel arrvial times. Journal of Maritime Economics and
Logistics. 11, 358, 2009.
54. Portillo, P.M., M.G. Ierapetritou and F.J. Muzzio Effects of rotation rate, mixing angle,
and cohesion in two continuous powder mixers A statistical approach. Powder
Technology. 194, 217, 2009.
55. Li, Z., and M.G. Ierapetritou Integrated planning and scheduling in a decomposition
framework. Chemical Engineering Science, 64, 3585, 2009.
56. Foteinou, P., E. Yang, G.K. Saharidis, M.G. Ierapetritou and I.P. Androulakis. A Mixed-
Integer Optimization Framework for the Synthesis and Analysis of Regulatory Networks.
Jl. Glob Optim. 43, 263, 2009.
57. Davis, E., and M.G. Ierapetritou. A Kriging Based Method for the Solution of Mixed-
Integer Nonlinear Programs Containing Black-Box Functions. Jl. Glob. Opt. 43, 191,
2009.
58. Ierapetritou, M.G. and Z. Jia. Short Term Scheduling Under Uncertainty: Sensitivity
Analysis. Encyclopedia of Optimization Second Edition, 3560-3567, C.A. Floudas and
P.M. Pardalos (eds), Springer, 2009.
59. Ierapetritou, M.G. and I. Banerjee. Shape Reconstruction Methods for Nonconvex
Feasibility Analysis Encyclopedia of Optimization Second Edition, 3491-3500, C.A.
Floudas and P.M. Pardalos (eds), Springer, 2009.
60. Ierapetritou, M.G. and Z. Jia. Gasoline Blending and Distribution Scheduling: An MILP
model. Encyclopedia of Optimization Second Edition, 1113-1127, C.A. Floudas and P.M.
Pardalos (eds), Springer, 2009.
15
61. Portillo P.M., Ierapetritou M.G., Tomassone M.S., Mc Dade C., Clancy D., Avontuur
P.C., and Muzzio F.J. Quality by Design Methodology for Development and Scale Up of
Batch Mixing Processes. Journal of Pharmaceutical Innovation. 3, 258, 2008.
62. Ierapetritou, M.G. and Z. Li. Modeling and Managing Uncertainty in Process Planning
and Scheduling. Springer volume in Optimization and Logistics Challenges in the
Enterprise. Kevin Furman and W. Art Chaovalitwongse (eds), Springer, 2008.
63. Portillo, P.M., M.G. Ierapetritou, and F.J. Muzzio Using Compartment Modeling to
Investigate Mixing Behavior of a Continuous Mixer. Jl. Ind. Pharm. 3, 161, 2008.
64. Euling, S.Y., Makris, S., Sen, B., White, L., Benson, R., Gaido, K.W., Kim, A.S., Hester,
S., Wilson, V.S., Keshava, C., Keshava, N., Foster, P.M., Androulakis, I.P., Ovacik, M.,
Ierapetritou, M.G., Gray, L.E., Thompson, C., and Chiu, W. An approach to using
genomics data in risk assessment: Dibutyl phthalate (DBP) case study. Birth Defects
Research Part a-Clinical and Molecular Teratology 82, 296, 2008.
65. Li, Z., and M.G. Ierapetritou. Reactive Scheduling Based On Parametric Solution. AIChE
J., 47, 2610, 2008.
66. Li, Z., and M.G. Ierapetritou. Robust optimization for process scheduling under
uncertainty. Ind. Eng.Chem. Res. 47, 4148, 2008.
67. He, K., M.G. Ierapetritou and I.P. Androulakis. A graph-based approach for developing
adaptive representations of complex reaction mechanisms. Comb. & Flame 155, 585,
2008.
68. Portillo, P.M., M.G. Ierapetritou, and F.J. Muzzio Characterization of Continuous
Convective Powder Mixing Processes. Powder Technology. 182, 368, 2008.
69. Li, Z. and M.G. Ierapetritou Process scheduling under uncertainty: Review and
challenges. Comp. Chem. Eng 32, 715, 2008.
70. Furman, K.C., Z. Jia, M.G. Ierapetritou A robust event-based continuous time formulation
for tank transfer scheduling. Ind. Eng. Chem. Res. 46, 9126, 2007.
71. Li, Z. and M.G. Ierapetritou Process scheduling under uncertainty using multiparametric
programming. AIChE Jl. 53, 3183, 2007.
72. Li, Z. and M.G. Ierapetritou A new methodology for the general multiparametric mixed-
integer linear programming (MILP) problems Ind. Eng. Chem. Res. 46, 5141, 2007.
73. Wu, D. and M.G. Ierapetritou Hierarchical approach for production planning and
scheduling under uncertainty. Chem. Eng. & Process. 46, 1129, 2007
74. Ierapetritou, M.G. and Z. Jia Short-term scheduling of chemical process including
uncertainty. Control Engineering Practice. 15, 1207, 2007.
75. Davis, E. and M.G. Ierapetritou A kriging method for the solution of nonlinear programs
with black-box functions. AIChE Jl. 53, 2001, 2007.
76. Portillo P.M., Muzzio F.J., Ierapetritou M.G. Hybrid DEM-compartment modeling
approach for granular mixing. AIChE Jl 53 (1): 119, 2007.
77. Jia, Z. and M.G. Ierapetritou. Generate Pareto Optimal Solutions of Scheduling Problems
using Normal Boundary Intersection Technique. Comp. Chem. Eng. 31, 268, 2007.
78. Davis, E., and M.G. Ierapetritou Adaptive Optimization of Noisy Black-Box Functions
Inherent in Microscopic Models. Comp. Chem. Eng., 31, 466, 2007.
79. Goyal, V., and M.G. Ierapetritou. Stochastic MINLP Optimization using Simplicial
Approximation. Comp. Chem. Eng., 31, 1081, 2007.
80. Portillo, P. F. Muzzio and M.G. Ierapetritou. Characterizing Powder Mixing Processes
utilizing Compartment Models. Int. Jl. Of Pharm. 320, 14, 2006.
16
81. Jia, Z. and M.G. Ierapetritou. Uncertainty Analysis on the RHS for MILP problems.
AIChE J., 52, 2486, 2006.
82. Wu, D., and M.G. Ierapetritou. Improved Lagrangean Decomposition Approach for MILP
Problems. Comp. Chem. Eng. 30, 778, 2006.
83. Banerjee, I., and M.G. Ierapetritou. An Adaptive Reduction Scheme to Model Reactive
Flow. Comb. Flame, 144, 219, 2006.
84. Bindal, A., M.G. Ierapetritou, S. Balakrishnan, A. Makeev, I. Kevrekidis and A. Armaou.
Equation-free, coarse-grained computational optimization using timesteppers. Chem. Eng.
Sci. 61, 279, 2006.
85. Sharma, N., M.G. Ierapetritou and M.L. Yarmush. Novel Quantitative Tools for
Engineering Analysis of Hepatocyte Cultures in Bioartificial Liver Systems.
Biotechnology and Bioengineering, 92(3), 321, 2005.
86. Balakrishnan S., Roy A., Ierapetritou M.G., Flach G.P. and Georgopoulos P.G. A
Comparative Assessment of Efficient Uncertainty Analysis Techniques for Environmental
Fate and Transport Models: Application to the FACT Model. Journal of Hydrology 307
(1-4): 204-218 JUN 9 2005.
87. Banerjee, I., and M.G. Ierapetritou. Feasibility evaluation of nonconvex systems using
shape reconstruction techniques. Ind. Eng. Chem. Res., 44, 3638, 2005.
88. Goyal, V. and M.G. Ierapetritou. Multiobjective Framework for Modular Design
Generation Incorporating Demand Uncertainty, Ind. Eng. Chem. Res., 44, 3594 2005.
89. Sirdeshpande, A.R., M.G. Ierapetritou, M.J. Andrecovich, J.P. Naumovitz. Process
synthesis optimization and flexibility evaluation of air separation cycles. AIChE J., 51,
1190, 2005.
90. Goyal, V. and M.G. Ierapetritou. Deterministic framework for robust modular design with
integrated-demand data analysis. Ind. Eng. Chem. Res. 43, 6813, 2004.
91. Wu, D., and M.G. Ierapetritou. Cyclic Short-Term Scheduling of Multiproduct Batch
Plants using Continuous Time Formulation. Comput. Chem, Eng. 28, 2271, 2004.
92. Jia, Z., and M.G. Ierapetritou. Efficient short-term scheduling of refinery operations based
on a continuous time formulation. Comput. Chem. Eng. 28, 1001, 2004.
93. Jia, Z., and M.G. Ierapetritou. Short-Term Scheduling under Uncertainty Using MILP
Sensitivity Analysis. Ind. & Eng. Chem. Res., 43, 3782, 2004.
94. Hauksdottir, A.S., U. Zuhlke, M.G. Ierapetritou and V. Goyal. The Solution of
Simultaneous Decoupling and Pole Placement Problem using Global Optimization.
Special Issue of Comp. Chem. Eng. The integration of Process Design and Control,
Panos Seferlis, Michael Georgiadis (Eds) Elsevier, 582, 2004.
95. Goyal, V. and M.G. Ierapetritou. Computational Studies using a Novel Simplicial-
approximation based Algorithm for MINLP Optimization. Comput. Chem. Engng. 28,
1771, 2004.
96. Banerjee, I., and M.G. Ierapetritou. Model Independent Parametric Decision Making.
Ann. Oper. Res., 132, 135, 2004.
97. Goyal, V. and M.G. Ierapetritou. MINLP Optimization Using Simplicial Approximation
Method for Classes of Nonconvex Problems. In Nonconvex Optimization and Its
Applications #74: Frontiers in Global Optimization, C.A. Floudas and P.M. Pardalos
(Eds), Springer, 2003, page 165.
98. Banerjee, I., and M.G. Ierapetritou. Development of an Adaptive Chemistry Model
Considering Micromixing Effects. Chem. Eng. Sci, 8, 4537, 2003.
17
99. Goyal, V. and M.G. Ierapetritou. Framework for Evaluating the Feasibility/Operability of
Nonconvex Processes. AIChE J, 49, 1233, 2003.
100. Jia, Z., and M.G. Ierapetritou. Mixed Integer Programming Model for Gasoline Blending
and Distribution Scheduling, Ind. Eng. & Chem. Res., 42, 825, 2003.
101. Bindal, A., M.G. Ierapetritou and J.Khinast. Adaptive Multiscale Solution of Dynamical
Systems in Chemical Processes Using Wavelets. Comp. Chem. Eng., 27, 131, 2003.
102. Wu, D., and M.G. Ierapetritou. Decomposition Approaches for the Efficient Solution of
Short-Term Scheduling Problem. Comp. Chem. Eng., 27, 1261, 2003.
103. Banerjee, I., and M.G. Ierapetritou. Process Synthesis under Parameter Variability.
Comput. Chem. Eng., 27, 1499, 2003.
104. Jia, Z., M.G. Ierapetritou and J. D. Kelly. Refinery Short-term Scheduling Using
Continuous Time Formulation Crude Oil Operations, Ind. Eng. & Chem. Res, 42, 3085,
2003.
105. Balakrishnan, S., A. Roy, M.G. Ierapetritou, G.P. Flach, and P. Georgopoulos.
Uncertainty Reduction and Characterization of Complex Environmental Fate and
Transport Models: An Empirical Bayesian Framework Incorporating the Stochastic
Response Surface Method. Water Resources Research, 39(12): 1350, 2003.
106. Goyal, V. and M.G. Ierapetritou. Integration of Data Analysis and Design Optimization
for the systematic Generation of Equipment Portfolio. Ind. & Eng. Chem. Res, 42, 5204,
2003.
107. Balakrishnan, S., P. Georgopoulos, I. Banerjee and M.G. Ierapetritou. Uncertainty
Considerations in the Complex Kinetic Mechanisms Reduction. AIChE J, 48, 2875, 2002.
108. Banerjee, I., and M.G. Ierapetritou. Design Optimization under Parameter Uncertainty for
General Black Box Models. Ind. & Eng. Chem. Res., 41, 6687, 2002.
109. Ierapetritou, M.G., D. Wu, J. Vin, P. Sweeney, M. Chigirinskiy. Cost Minimization in an
Energy Intensive Plant Using Mathematical Programming Approaches. Ind. & Eng.
Chem. Res, 41, 5262, 2002.
110. Goyal, V. and M.G. Ierapetritou. Determination of Operability Limits Using Simplicial
Approximation. AIChE J, 48, 2902, 2002.
111. Ierapetritou, M.G. and J.Khinast. A New Stability Analysis Approach for Chemical
Reactors Based on Iterative Sampling and Optimization. AIChE J., 48, 187, 2002.
112. Vin, J., and M.G. Ierapetritou. Robust Short-Term Scheduling of Multiproduct Batch
Plants under Demand Uncertainty. Ind. & Eng. Chem. Res, 40, 4543, 2001.
113. Ierapetritou M.G., and C.A. Floudas. Comments on "An improved RTN continuous-time
formulation for the short-term scheduling of multipurpose batch plants". Ind. & Eng.
Chem. Res, 40, 5040, 2001.
114. Sirdeshpande, A., M.G. Ierapetritou, and I.P. Androulakis. Design of Flexible Reduced
Kinetic Mechanisms. AIChE J., 47, 2461, 2001.
115. Floudas, C.A., Z. Gumus, and M.G. Ierapetritou Global Optimization for the Feasibility
Test and Flexibility Index Problems, Ind. & Eng. Chem. Res, 40, 4267, 2001.
116. Ierapetritou, M.G. A New Approach for Quantifying Process Feasibility: Convex and one
Dimensional Quasi-Convex Regions. AIChE J., 47, 1407, 2001.
117. Ierapetritou, M.G. Bilevel Optimization: Feasibility Test and Flexibility Index
Encyclopedia of Optimization, C.A. Floudas and P.M. Pardalos (eds), Kluwer Academic
Publisher, Printed in the Netherlands, 2001.
18
118. Ierapetritou, M.G. MINLP: Application in Facility Location-Allocation Encyclopedia of
Optimization, C.A. Floudas and P.M. Pardalos (eds), Kluwer Academic Publisher, Printed
in the Netherlands, 2001.
119. Ierapetritou, M.G. Single Facility Location: Multi-objective Rectilinear Distance Location
Encyclopedia of Optimization, C.A. Floudas and P.M. Pardalos (eds), Kluwer Academic
Publisher, Printed in the Netherlands, 2001.
120. Ierapetritou, M.G. Single Facility Location: Multi-objective Euclidean Distance Location
Encyclopedia of Optimization, C.A. Floudas and P.M. Pardalos (eds), Kluwer Academic
Publisher, Printed in the Netherlands, 2001.
121. Vin, J., and M.G. Ierapetritou. A New Approach for Efficient Rescheduling of
Multiproduct Batch Plants. Ind. & Eng. Chem. Res, 39, 4228, 2000.
122. Ierapetritou M.G., I.P. Androulakis, D.S. Monos and C.A. Floudas, Structure Prediction
of Binding Sites of MHC Class II Molecules based on the Crystal of HLA-DR1 and
Global Optimization, State of the Art in Global Optimization: Computational Methods
and Applications, Eds: C.A. Floudas and P.M. Pardalos, Kluwer, 2000.
123. Ierapetritou M.G., T.S. Hene and C.A. Floudas, Effective Continuous-Time Formulation
for Short-Term Scheduling: III Multiple Intermediate Due Dates Ind. & Eng. Chem, 38, 9,
3446, 1999.
124. Ierapetritou M.G., and C.A. Floudas and S. Vansantharajan and A.S. Gullick, A
Decomposition Based Approach for Optimal Location of Vertical Wells AIChE J., 45, 4,
844, 1999.
125. Ierapetritou M.G., and C.A. Floudas, Effective Continuous-Time Formulation for Short-
Term Scheduling: I. Multipurpose Batch Processes Ind. & Eng. Chem. Res., 37, 11, 4341,
1998.
126. Ierapetritou M.G., and C.A. Floudas, Effective Continuous-Time Formulation for Short-
Term Scheduling: II. Multipurpose/Multiproduct Continuous Processes Ind. & Eng.
Chem. Res., 37, 11, 4360, 1998.
127. Ierapetritou, M.G, and C.A. Floudas, Short-Term Scheduling: New Mathematical Models
vs Algorithmic Improvements. Comp. & Chem. Eng., 22, S419, 1998.
128. Klepeis, J.L., M.G. Ierapetritou, and C.A. Floudas, Protein Folding and Peptide Docking:
A Molecular Modeling and Global Optimization Approach. Comp. & Chem. Eng., 22, S3,
1998
129. Klepeis, J.L., I.P. Androulakis, M.G. Ierapetritou, and C.A. Floudas, Predicting Solvated
Peptide Conformations via Global Minimization of Energetic atom-to-atom Interactions.
Comp. & Chem. Eng., 22, 765, 1998
130. Androulakis I.P., N.N. Nayak, M.G. Ierapetritou, D.S. Monos and C.A. Floudas,
Identification of Peptide Binding Specificity for Pocket 1 of HLA-DR1 Based on Global
Minimization of Energy Interactions. Proteins: Structure, Function and Genetics, 29, 87,
1997.
131. Epperly T., M.G. Ierapetritou and E.N. Pistikopoulos, On the global and efficient solution
of stochastic batch plant design problems Comp. & Chem. Eng., 21, 1411, 1997.
132. Ierapetritou, M.G., E.N. Pistikopoulos and C. A. Floudas, Operational Planning Under
Uncertainty. Comp. & Chem. Eng., 20, S1209, 1996.
133. Ierapetritou, M.G. and E. N. Pistikopoulos, Batch Plant Design and Operations under
Uncertainty Ind. & Eng. Chem. Res., 35, 772, 1996.
19
134. Ierapetritou, M.G., J. Acevedo and E.N. Pistikopoulos, An Optimization Approach for
Process Engineering Problems under Uncertainty. Comp. & Chem. Eng., 20, 703, 1996.
135. Pistikopoulos, E.M, T.V. Thomaidis, M. G. Ierapetritou and A. Melin, Flexibility,
Reliability and Maintenance considerations in Batch Plant Design Comp. & Chem. Eng.,
20, S1209, 1996.
136. Ierapetritou, M.G. and E. N. Pistikopoulos, Global Optimization for Stochastic Planning
Scheduling and Design Problems Global Optimization in Engineering Design,
I.E.Grossmann (ed), Kluwer Academic Publisher, Printed in the Netherlands, 231-287,
1996.
137. Visweswaran V., Floudas C.A., Ierapetritou, M.G. and Pistikopoulos E.N., A
Decomposition Based Global Optimization Approach for Bi-Level Convex Programming
Problems. State of the Art in Global Optimization: Computational Methods and
Applications C.A. Floudas and P.M. Pardalos (eds), Springer, 139-162, 1996.
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