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Engineering Supply Chain

Location:
Piscataway Township, NJ
Posted:
February 12, 2013

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Resume:

CURRICULUM VITAE

MARIANTHI G. IERAPETRITOU

Department of Chemical & Biochemical Engineering, RUTGERS UNIVERSITY

** ***** ****, **********, ****, NJ 08854-8058 USA

Tel: 848-***-****; Fax: 732-***-****; E-mail: abqjlh@r.postjobfree.com

URL: http://sol.rutgers.edu/staff/marianth

EDUCATION

1991-1995 Ph. D., Chemical Engineering Department, Imperial College, London, UK.

Faculty Advisor: Prof. Efstratios Pistikopoulos

Thesis Topic: "Optimization Approaches for Process Engineering Problems

under Uncertainty"

1986-1991 Diploma (Summa cum Laude), Chemical Engineering Department, NTUA,

Greece

Faculty Advisor: Prof. Z. Maroulis

Thesis Topic: "Synthesis of Heat Exchanger Network"

PROFESIONAL EXPERIENCE

2009- present Professor

Department of Chemical & Biochemical Engineering Rutgers University,

Piscataway, NJ

2004-2009 Associate Professor

Department of Chemical & Biochemical Engineering Rutgers University,

Piscataway, NJ

2005-2006 Visiting Associate Professor

Department of Chemical Engineering, MIT

Cambridge, MA

1998-2004 Assistant Professor

Department of Chemical & Biochemical Engineering Rutgers University,

Piscataway, NJ

1996-1998 Post Doctoral Research Associate

Department of Chemical Engineering, Princeton University, Princeton, NJ

Faculty Advisor: Prof. Christodoulos A. Floudas

1995-1996 Post Doctoral Research Associate

Center for Process Systems Engineering, Imperial College, London, UK

Faculty Advisor: Prof. Efstratios Pistikopoulos

RESEARCH INTERESTS

Computer-Aided Process and Product Design; Production Planning, Scheduling and Supply

Chain Management; Scheduling under Uncertainty; Uncertainty Considerations in Process

Design and Operations; Decomposition based Techniques for Complex Systems; Reaction

Model Reduction; Modeling and Optimization of Pharmaceutical Processes; Modeling and

Optimization of Liver Metabolism in Response to Stressors.

ACCOMPLISHEMTS

1

HONORS AWARDS

2012 Outstanding Faculty Award, School of Engineering, Rutgers University

2004 Board of Trustees Research Award for Scholarly Excellence, Rutgers University

2001-2002 Teaching Excellence Award from Chemical Engineering Department, Rutgers

University

2000-2004 NSF CAREER Award, CTS 99-83406

1992-1994 Postgraduate Grant, Commission of European Community (ERB CHBI CT 93

0484)

1991-1992 Research/Teaching Fellowship, Imperial College

1986-1991 Undergraduate Fellowship, National Scholarship Foundation of Greece Award

1990-1991 Tiftixis Foundation Award, Athens Greece

1991 Economou Award for Academic Excellence, Athens, Greece

1991 Best Student of Chemical Engineering Department Award, National Technical

University of Athens

RESEARCH GRANTS

1. NSF Award 2012-2015 ($342,575) Integration of scheduling and control using closed loop

implementation (single PI)

2. NSF Award 2010-2013 ($343,901) Innovative methodologies for integrated planning and

scheduling and industrial applications (single PI)

3. Office of Naval Research 2010-2013 ($328,128) Modeling complexities in biofuel

combustion (PI, co-PI Ioannis Androulakis)

4. NSF Award 2009-2012 ($1,800,000) Commercializing of Continuous Pharmaceutical

Manufacturing Technology (PI, co-PI Fernando Muzzio, Gintaras Reklaitis, James Donald

Litster (Purdue), Raj Dave (NJIT),

5. NSF Graduate Research Supplement 2009-2010 ($53,938) (single PI)

6. NSF REU supplement 2009 ($12,000)

7. NSF Graduate Research Supplement 2008-2009 ($46,871) (single PI)

8. NIH Grant RO1 2008-2011 ($1,200,000) Bioinformatics Analysis of Control Mechanisms

of Hypermetabolism (co-PI with Ioannis Androulakis (PI), Charles Roth and Francois

Berthiaume)

9. NSF Award 2007-1010 ($316,317) Reactive Flow Simulation Using An Adaptive

Chemistry Framework (co-PI with Ioannis Androulakis (PI)).

10. NSF Award 2006-2009 ($399,572) Systematic Mathematical Strategies for Stochastic

Modeling and Uncertainty in Production Planning and Scheduling (single PI).

11. Office of Naval Research 2006-2009 ($270,782) Efficient Characterization of Combustion

Fuels (PI, co-PI Ioannis Androulakis)

12. National Center of Excellence for Environmental Bioinformatics and Computational

Toxicology EPA 2005-2010 ($4,500,000 ) (co-PI with William Welsh (PI), Panos

Georgopoulos, from Robert Wood Johnson Medical School, Ioannis Androulakis from

Rutgers University and Herschel Rabitz and Chris Floudas from Princeton University)

13. Metabolic Engineering National Science Foundation 2005-2008 ($998,659) Molecular

Network Controls of Hepatocyte Metabolism (co-PI with Charles Roth (PI), Martin

Yarmush and Ioannis Androulakis from Rutgers University)

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14. Quantitative Systems Biology National Science Foundation 2004-2007 ($500,000)

Experimental and Computational Studies to Optimize Hepatocyte Function (PI with

Charles Roth and Martin Yarmush from Rutgers University).

15. NSERC Strategic Grant 2004-2007 ($300,000) Innovative Approach to the Optimization

of Integrated Newsprint Mill Dynamic Operations (Co-PI with Professor Paul Stuart from

Ecole Polytechnique in Montreal).

16. Office of Naval Research 2003-2006 ($213,000) Development of an Adaptive Chemistry

Model for Combustion Systems Considering Micromixing Effects (single PI)

17. NSF Award 2002-2005 ($200,000) Design of Flexible Reaction Models (single PI)

18. CAREER NSF Award 2000-2004 ($308,803) Process Operations: Decision-Making under

Uncertainty (single PI).

19. Strategic Resource and Opportunity Analysis (SROA) ($80,000), Rutgers University The

Laboratory for Multiphase Reactive Flow (LMRF): Integrating Information Technology and

Experiments for Maintaining Technological Superiority in Homeland Security, Energy

Generation, and the Environment (Co-PI)

20. ACS-PRF Type G "Starter" Grant ($25,000) Incorporation of Uncertainty into Complex

Kinetic Mechanisms (single PI).

21. New Jersey Space Consortium Grant (NASA) ($25,000) Order Reduction of Complex

Kinetic Mechanisms Considering Micro-mixing Effects (single PI).

22. NSF International Division Grant, 0071505 ($13,800) Multiple Inputs - Multiple Outputs

(MIMO) Control Design (single PI).

23. Grant from BOC Gases ($43,000) to perform research on novel optimization approaches for

design under uncertainty.

24. Grant from Honeywell Hi-Spec Solutions ($25,000) to investigate the application of

continuous time formulation for refinery scheduling.

25. Grant for Union Carbide ($5,000) to study the optimization of Amerchol Plant operations.

26. Grant from Rutgers University (co-PI along with Professors Narashiman, Khinast, Glasser,

and Moghe) to modernize the graduate curricula in Chemical Engineering ($48,000).

27. Grant form Rutgers University (co-PI along with Professors Lehman, Norris, Denda, and

Buttner) to advance instructional technology for engineering education by introducing new

computer-based learning resources ($112,000).

28. Together with Professor Manish Parashar from Electrical Engineering Department lead the

Unisys initiative to establish one of the three Nationwide Excellence Centers equipped with

initial computing network ($278,000).

29. Grant from Rutgers University to initialize the research effort towards the application of

optimization methods in environmental treatment systems ($1,500).

30. Grant from Rutgers University to initialize the research effort towards the consideration of

uncertainty into complex kinetic models ($1,500).

31. Undergraduate Research Fellowship to support a student to do research in the area of

scheduling of batch processes ($1,500).

32. Undergraduate Research Fellowship to support a student to do research in the area of

refinery scheduling ($1,500).

TEACHING ACTIVITIES

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2010-2011 Chemical Analysis I Sophomore level course

2004-2008 Undergraduate Executive Officer

2004/2009 Freshmen Orientation Lectures

2004-2012 Process Dynamics and Control Senior level course

2004 Graduate level Elective Course: Modeling and Optimization of Process Design

and Operations

2000-2002 Design of Separation Processes - Senior Level Course:

2005-2007 Graduate level Core Course: Analytical Methods in Chemical and Biochemical

Engineering

2001-2002 Analytical Methods in Chemical and Biochemical Engineering - Graduate level

Core Course

1999-2000 Advanced Transport Phenomena - Graduate level Core Course:

1999 Process Systems Engineering - Graduate level Course

MENTORING GRADUATE & UNDERGRADUATE STUDENTS AND POSTDOCTORAL

SCHOLARS

Postdoctoral Scholars Supervised

Ravendra Singh (12/2011- Present)

Research Area: Process Integration and Control of Pharmaceutical Processes.

Jey Arjunan (10/2010 05/2011)

Research Area: Process Integration and Optimization of Pharmaceutical operations.

Vidya Iyer (06/2007 05/2010)

Research Area: Metabolic Engineering of Liver Cell Cultures

George Saharidis (03/2007- 12/2008)

Research Area: Decomposition Based Optimization of Complex Systems

Zhenya Jia (01/2007 02/2009)

Research Area: Modeling, Optimization and Control of Pharmaceutical Systems

Antoine Berton (03/2005 03/2006)

Research Area: Optimization and Control of Pulp and Paper Processes

cole Polytechnique. Montr al

Avinash Sirdeshpande (9/1999-3/2001)

Research Area: Reduction of Complex Kinetic Models

Current Affiliation: BOC Gases

Current Graduate Students Advised/Co-Advised

Nihar Sahay Since January 2012

Ph.D. expected 2016

Thesis Title Modeling of Sustainable Chemical Supply Chain

Zhaojia Lin Since September 2011

Ph.D. expected 2015

Thesis Title Modeling and Optimization of Chemical and Fuel production from

Biomass

Jinjun Zhuge Since January 2011

Ph.D. expected 2015

Thesis Title Integration of Production Scheduling and Control

Shuliang Zhang Since September 2009 (co-advised by Prof. I.P. Androulakis)

Ph.D. expected May 2014

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Thesis Title Modeling of Complex Reaction Systems

Nikisha Shah Since September 2008

Ph.D expected May 2013

Thesis Title Optimization of Supply Chain Management

Fani Boukouvala Since September 2008 (co-advised by Prof. F. Muzzio)

Ph.D expected May 2013

Thesis Title Modeling and Optimization of Pharmaceutical Processes

Past Graduate Students Advised/Co-Advised

Ph.D.

Yijie Gao Ph.D April 2012 (co-advised by Prof. F. Muzzio)

Thesis Title Modeling of Continuous Powder Mixing

Aditya Vanarase Ph.D. August 2011 co-advised by Prof. F. Muzzio)

Investigation of continuous mixing of powders

Mehmet Orman Ph.D December 2011 (co-advised by Prof. I.P. Androulakis)

Thesis Title Bioinformatics Analysis of Control Mechanisms of Burn and Sepsis

Induced Inflammatory Response

Kai He Ph.D. June 2010 (co-advised by Prof. I.P. Androulakis)

Thesis Title Development of Kinetic Model Reduction Framework and its

Application in Realistic Flow Simulation

Beverly Smith Ph.D. June 2010

Thesis Title Product Design and New Product Portfolio Management Modeled

Integration and Optimization

Zukui Li Ph.D. May 2010.

Thesis Title Process Operations with Uncertainty and Integration Considerations

Hong Yang Ph.D. December 2009 (co-advised by Prof. C.M.Roth)

Thesis Title: Design and analysis of Amino Acid supplementation in Hepatocyte

culture using in vitro experiment and mathematical modeling

Eddie Davis Ph.D. August 2008

Thesis Title: Modeling and Optimization of Process Engineering Problems

Containing Black-Box Systems and Noise

Patricia Portillo Ph.D. May 2008 (co-advised by Prof. F. Muzzio)

Thesis Title: Modeling, Control and Optimization of Continuous Pharmaceutical

Processes

Nripen Sharma Ph.D. January 2007. (co-advised by Prof. M.L.Yarmush)

Thesis Title: Metabolic Engineering of Stem Cell Differentiation

Tien Phong Huynh Masters October 2007 (co-advised by Prof. I.P. Androulakis)

Thesis Title Characterization of Complex Fuels for Combustion Applications

Zhenya Jia, Ph.D. September 2005.

Thesis Title: Uncertainty Analysis of Scheduling and Planning Problems.

Ipsita Banerjee Ph.D. May 2005.

Thesis Title: Multiscale Framework for Coupling Micromixing Phenomena and

Detailed Kinetic Networks for Combustion Systems in a Dynamic

Environment.

Dan Wu Ph.D. May 2005.

Thesis Title: Unified Frameworks for the Optimal Production Planning and

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Scheduling.

Vishal Goyal Ph.D. Jan 2005.

Thesis Title: Design and Synthesis of Flexible Module-Based Systems.

Aditya Bindal Ph.D. October 2004 (co-advised by Prof. J. Khinast)

Thesis Title: Optimization and Stability Analysis of Multidimensional Reacting

Systems

Masters

Amalia Nikolopoulou Masters December 2011

Thesis Title Hybrid Simulation Based Optimization for Supply Chain

Management

Steve Guzikowski Masters January 2008 (co-advised by Prof. C.M.Roth)

Thesis Title: Novel tools towards Improving Hepatocyte Function

Ian Glasgow Masters Dec 2005 (co-advised by Prof. P. Stuart Ecole

Polytechnique de Montreal, Montreal, Canada)

Thesis Title: Optimization Applications in Pulp Paper Process Industry

Suhrid Balakrishnan Masters September 2002 (Co-advised with Prof. P. Georgopoulos).

Thesis Title: Uncertainty considerations in Atmospheric Systems

Jeetmanyu Vin Masters July 2000

Thesis Title: Short Term Scheduling of Batch Plants under Uncertainty.

Member of PhD Committee

Qian Yang Ph.D. May 2012(Primary Advisor: Prof. I.P. Androulakis, CBE

Rutgers University)

Dynamics of Gene Expression Profiling in Liver Following Thermal

Injury and Sepsis

Alisa Vasilenko Ph.D. August 2011 (Primary Advisor: Prof. Muzzio, CBE Rutgers

University)

Rheological properties of granular materials

Eric Jayjock Ph.D. May 2011 (Primary Advisor: Prof. Muzzio, CBE Rutgers

University)

Advanced Data Inversion Applied to Cascade Impactor Design

Brenda Remy Ph.D. May 2010 (Primary Advisor: Prof. Glasser, CBE Rutgers

University)

Granular Flow, Segregation and Agglomeration in Bladed Mixers

Meric A. Ovacik Ph.D. May 2010 (Primary Advisor: Prof. Androulakis, BME Rutgers

University)

Modeling Pathways of Transcriptional Profiling of in Utero DBP

Exposure in Rat Testes

Kiran Vyakaranam Ph.D. May 2009 (Primary Advisor: Prof. Kokini, Food Science,

Rutgers University)

Thesis Title: Air Bubble Dynamics during Continuous Mixing of Viscous Liquids

Bharani Kumar

Ashokan Ph.D. October 2008 (Primary Advisor: Prof. Kokini, Food Science,

Rutgers University)

Thesis Title: Developing Methods for Design and Scale-up of Continuous Mixers

through 3D Numerical Simulation of Flow and Mixing

Marcos Llusa Ph.D. May 2008 (Primary Advisor: Prof. F. Muzzio)

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Thesis Title: Effect of shear mixing on the agglomeration of cohesive granular

material and the lubrication of granular blends

Jeng-Shiou Chen Ph.D. December 2007 (Primary Advisor: Prof. J. Khinast)

Thesis Title: Transition Metal Catalysts for Suzuki Couplings and Chiral

Hydrogenations: Kinetic Study, Computational Model and Synthesis

Paloma Pimenta Ph.D. June 2008 (Primary Advisor: Prof. H. Pedersen)

Thesis Title: Surfactant Solutions and Nanoparticle Suspensions

Thomas W Cochran Ph.D. June 2005 (Primary Advisor: Prof. Y. Chiew)

Thesis Title: Molecular Thermodynamic Modeling of Amorphous Solid Phase of

Chain Molecules

Xue Liu Ph.D. January 2005 (Primary Advisor: Prof. B. Glasser)

Thesis Title: Instability and Segregation in Bounded Gas-Particle Fluidized beds

Athanas Koynov Ph.D. May 2005 (Primary Advisor: Prof. J. Khinast).

Thesis Title: Computational Studies of Bubble Columns

Qinghua Wang Ph.D. September 2002 (Mechanical Engineering Department,

Rutgers

University, Primary Advisor: Prof. Y. Jaluria).

Thesis Title: Instability and Heat Transfer in Mixed Convection Flow in a

Horizontal Duct with Application to Cooling of Electronic Systems

Joe Kukura II Ph.D. July 2003 (Primary Advisor: Prof. F. Muzzio).

Thesis Title: Computational Investigation of Laminar Mixing in Pharmaceutical

Tanks

Christine Switzer Ph.D. May 2003 (Primary Advisor: Prof. D. Kosson).

Thesis Title: Soil Vapor Extraction and Air Sparging Remediation of

Trichlorethylene Contamination at the Savannah River Site

Elizabeth Shen Ph.D. 2001 (Primary Advisor: Prof. B. Narasimhan).

Thesis Title: Microphase Separation in Bioerodible Polyanhydrides for

Controlled Drug Release

Tongdan Jin Ph.D. 2001 (Industrial Engineering Department, Rutgers

University, Primary Advisor: Prof. D. Coit).

Thesis Title: System Reliability Assessment and Optimization Considering

Estimation Uncertainty

Stephano Cerbelli Ph.D. 2000 (Primary Advisor:Prof. F. Muzzio).

Thesis Title: The Topology of Mixing Structures in two-dimensional Periodic

and Aperiodic Chaotic Flows

Undergraduate Students Advised

Chaitali Inamdar, Uncertainty propagation in pharmaceutical modeling, Spring 2012-Summer

2012.

Jonathan E. Gajda, Segregation studies in continuous mixing, Summer 2012.

Lukasz Mioduszewski, Modeling of Pharmaceutical Processes. Fall 2010-Spring 2011.

Catherine Polyakov, Analyzing flux data for liver exposure to toxicants. Summer 2010.

Chris Doe, Studying hepatotoxicity due to environmental toxicants. Summer 2009, Fall 2009.

Nikisha Shah, Centralized Decentralized Optimization for Refinery Scheduling, Slade

Scholar honor student, Fall 2007- Spring 2008.

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Roentgen Hau, Examining the Content Uniformity of Powder Blends Using Near-Infrared

Spectroscopy, Slade Scholar honor student, Fall 2007-Spring 2008.

Lily Cheung Chang, Cell Growth and Urea Production in Hepg2 Cells under Different Insulin

and Glucose Concentration in the Media, Slade Scholar honor student, Fall 2007-Spring 2008

Sarah Abdelsayed, Optimization of supplementation for hepatocyte utilization in Bioartificial

liver devices, Fall 2007.

Timothy Lin, Understanding of acetaminophen (APAP) metabolism and induced-

hepatotoxicity, Fall 2005 Spring 2006

Adebola Ogunniyi, Development of Response Surfaces for Optimization of Noisy Black-Box

Systems, Fall 2004-Spring 2005

Yuliana Lugo, Application of MATLAB s model predictive control toolbox to mixing

processes, Summer 2006, RISE student.

Fred Bidrawn, Sensitivity analysis for Mixed Integer Linear Programming problems, Fall 2004.

Victor Low, Reduction of combustion chemistry, Spring- Summer 2007.

Salah Issa, Investigating the performance of hepatocyte cultures, Fall 2005- Spring 2006.

Enrique Coronado, Short-term Scheduling of Pharmaceutical Plants, Fall 2002.

Kimberly Ward, Design of a Graphical Interface for Scheduling of Batch Plants, Fall 2000,

Spring 2001.

Melissa Gregory, Integrating Energy Price Forecasting with Design Optimization of Energy

Intensive Plants, Spring 2001.

Regina Galie, Scheduling of Refinery Operations, Fall 2001.

Miral Parikh Design and Optimization of Air Separation Plant, SUPER Douglass College of

women Student, Spring 2001

Rinku Parikh, Model Reduction of Complex Kinetic Networks, Slade Scholar honor student-

Fall 2000 Spring 2002.

Claire Pinto, Short-term Scheduling of Multi-Product Batch Plants, Spring 2000.

Nisha Batra, Uncertainty Considerations In Atmospheric Kinetic Modeling, Spring 1999.

Pauline Voung, Flexibility Evaluation of Batch Processes. Fall 1998.

Grace Zougheib, Modeling of Short-term Scheduling of Batch Plants, Fall 1998.

UNIVERSITY SERVICE

Chair of the Committee on Appointments and Promotions 2010-2011

Committee on Appointments and Promotions 2009-2010

Faculty Secretary, SOE 2009-2011

Dean s Advising Committee 2009-2011

Member of New Brunswick Faculty Council 2011-2012

Faculty Admissions Committee 2009-2012

Undergraduate Executive Officer 2004-2008

Advisor Society of Women Engineers 2007-2008

Member of School of Engineering Rules of Procedure Committee 2003-2004

Chair of Graduate Admissions Committee 2001-2002

All Class Advisor 2000-2008

Departmental Web Site Coordinator 2000-present

Member of RUTCOR (Rutgers Center of Operations Research) 2000-present

Participation in program SUPER of Douglass College of women.

Chair, School of Engineering Student Discipline Committee 2000-present

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Member of the Departmental Admissions and Recruiting Committee 1998-2004

Member of the Departmental Qualifying Committee 1998-1999

Member of the Departmental Computing Committee 1998-1999

Member of the Departmental Promotional Material Committee 1998-1999

Junior Advisor 1999-2000

PROFESSIONAL ACTIVITIES

Conference Organizer

FOCAPO (Foundations of Computer Aided Process Operations) Conference, 2008

Membership in Professional Societies

Elected AIChE Computing and Systems Technology (CAST) director 2008-2010

Elected as a Trustee of the CACHE, the leading organization within the Chemical Engineering

community promoting computational applications

Member of American Institute of Chemical Engineers (AIChE)

Member of Institute of Operations Research and Management Sciences (INFORMS)

Member of Society of Industrial and Applied Mathematics (SIAM)

AIChE Computing and Systems Technology (CAST) Nominated and elected 10a (Systems and

Process Design) Division Director for 2006

Conference Organizing Committees

Organizing Committee: ESCAPE 16, ESCAPE 17, PSE 2006, ESCAPE 18, ESCAPE 21,

Annual Meeting of Creek Chemical Engineers, PSE 2009, FOCAPD 2009,

FOCAPO/CPC2012.

Chairing on Technical Meetings

Optimization I, European Symposium of Computer Aided Process Engineering (ESCAPE) 21,

Greece, June 2011 (Chair)

Supply Chain and Logistics Optimization AIChE Meeting, November 2007, Salt Lake City, UT

(Chair)

Design Analysis and Operations Under Uncertainty, AIChE Meeting, November 2007, Salt

Lake City, UT (Chair)

Planning and Scheduling, AIChE Meeting, November 2007, Salt Lake City, UT (co Chair)

Uncertainty in Process Design and Operations AIChE Meeting, November 2006, San

Francisco, CA (Chair).

Advances in Optimization I &II AIChE Annual Meeting, November 2005, Cincinnati, OH

(Chair).

Process Design and Operation Under Uncertainty, AIChE Annual Meeting, November

2005,Cincinnati, OH (Chair).

Computing Methods for CAPE, ESCAPE 15, May 2005, Barcelona, Spain (Chair).

Supply Chain Management I, AIChE Annual Meeting, November 2004, Austin, TX (Vise-

Chair).

Supply Chain Management II, AIChE Annual Meeting, November 2004, Austin, TX (Vise-

Chair).

Chair for Enabling Technologies in Product and Process Design: Operations, FOCAPD,

Princeton, NJ, July 2004

Manufacturing and Process Operations, ESCAPE 14, Lisbon, May 2004 (Chair)

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Enterprise Wide Optimization, AIChE Annual Meeting, November 2003, San Francisco, CA

(Chair).

Modeling and Computation for Process Design, AIChE Annual Meeting, November 2002,

Indianapolis, NV (Vice Chair).

Planning and Scheduling, AIChE Annual Meeting, November 2002, Indianapolis, NV (Vice

Chair).

Flexibility and Operability in Design, AIChE Annual Meeting, November 2001, Reno, NV

(Chair).

Applications of System Analysis Tools in Information Processing, AIChE Annual Meeting,

November 2001, Reno, NV (Vice Chair).

Applications of Scheduling and Planning in Batch Processes, AIChE Annual Meeting,

November 2001, Reno, NV (Chair).

Process Operations, 7th International Symposium on Process Systems Engineering (PSE) 2000,

Collorado (Chair).

Planning and Scheduling AIChE Annual Meeting, November 2000, Los Angeles, CA (Chair).

Design of Reactive Separation Systems, AIChE Annual Meeting, November 2000, Los

Angeles, CA (Chair).

Planning, Scheduling and Supply Chain Management, AIChE Annual Meeting, November

1999, Dallas, TX (Chair)

Batch Processing, AIChE Annual Meeting, November 1998, Miami Beach, FL (Chair).

Flexibility in Process Operations, AIChE Annual Meeting, November 1998, Miami Beach, FL

(Chair).

Design for Flexibility and Operability, AIChE Annual Meeting, Miami Beach, Nov 1998

(Chair).

COLLABORATIONS

Rutgers University

Professor Georgopoulos: in the area of sensitivity and uncertainty analysis in contaminant

source-to-dose sequence.

Professor Boros from Rutgers Center of Operations Research (RUTCOR) in the area of

introducing optimization theory in engineering.

Professor Coit from the department of Industrial Engineering in the area of Multiobjective

optimization of process operations under uncertainty

Professor Roth from Chemical and Biochemical Engineering and Biomedical engineering

departments in the area of hepatocyte functionality optimization.

Professor Androulakis from Biomedical engineering in the area of modeling regulatory

networks.

Professor Yarmush from Biomedical Engineering: co-advise of one PhD thesis in the area

of modeling and optimization of metabolic networks.

External

Professor Michel Minoux from University of Paris 6 in decomposition based methods.

Professor Anna Soffia Hauksdottir from University of Iceland a pioneer in the process

control field.

Professor Paul Stuart from Ecole Polytechnic in Montreal Canada in the area of

optimization in pulp and paper industry.

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Professor Yannis Kevrekides from Princeton University, in the area of optimization of

multiscale dynamic systems.

Dr Jeff Kelly Honeywell Hi-Spec Solutions in the area of refinery scheduling.

Dr Kevin Furman from ExxonMobil Research Engineering, in the area of supply chain

modeling and optimization.

Dr John Farell from ExxonMobil Research Engineering, in the area reduction of complex

reaction networks.

REFEREEING/REVIEWING ACTIVITY

Associate Editor

Journal of Natural Gas Science and Engineering Elsevier

Scientific Conference Reviewer

European Symposium of Computer Aided Process Engineering (ESCAPE)- 22 (2012)

European Symposium of Computer Aided Process Engineering (ESCAPE)- 21 (2011)

Process Systems Engineering International Meeting PSE 2009

Foundations of Computer Aided Process Design FOCAPD 2009

17th IFAC World Conference 2008

ACC (American Control Conference) 2006 Conference

8th International Symposium on Dynamics and Control of Process Systems (DYCOPS 2007)

ADCHEM (Advanced Control of Chemical Processes) Conference 2006

European Symposium of Computer Aided Process Engineering (ESCAPE)-16 / Process

Systems Engineering (PSE 2006)

Foundations of Computer Aided process Operations 2003 (FOCAPO)

European Symposium of Computer Aided Process Engineering (ESCAPE)- 6 (1996)

Scientific Journal Reviewer

Chemical Engineering Research and Design

Engineering Optimization

Computers and Chemical Engineering

AIChE Journal

Industrial Engineering & Chemistry Research

Energy and Fuels

Combustion and Flame

Optimization and Engineering,

Chemical Engineering Communications

Chemical Engineering Science

European Journal of Operations Research

Computers and Industrial Engineering

Applied Mathematical Modeling

European Journal of Operations Research

Biotechnology and Bioengineering

Metabolic Engineering

Journal of Zhejiang University SCIENCE (JZUS)

The International Journal

Discrete Event Dynamic System

IEEE Transactions on Dielectrics and Electrical Insulation

Proposal Reviewer

11

National Science Foundation

National Science Foundation CAREER Panel, ITR Panel, EFRI Panel, CDI Panel, IGERT

Panel

Petroleum Research Fund (ACS).

FEATURED WORK

Spotlight feature Biotechnology and Bioengineering Effects of glucose and insulin on HepG2-

C3A cell metabolism, 2010.

Chemical Engineering Progress "Simplifying Kinetic Models" 97:11, 16, November 2001.

CITATIONS- IMPACT

No of citations: 1702; h-index 20 (source: Web of Science: Science Citation Index)

BOOKS AUTHORSHIP

M.G Ierapetritou, M. Minoux, G. Saharidis. Review of Decomposition Algorithms:

Applications to Large Scale Engineering problems. In preparation.

REFEREED JOURNAL PUBLICATIONS AND BOOK CHAPTERS

1. Mattick, J.,Yang, Q.,Orman, M., Ierapetritou, M.G., Berthiaume, F., Androulakis,

I.P.Long-term gene expression profile dynamics following cecal ligation and puncture in

the rat. Journal of Surgical Research, Available online,

http://dx.doi.org/10.1016/j.jss.2012.03.052.

2. Shah, N.K., Ierapetritou, M.G. Integrated production planning and scheduling

optimization of multisite, multiproduct process industry. Computers and Chemical

Engineering. 37, 214, 2012.

3. He, K., Ierapetritou, M.G., Androulakis, I.P. Exploring Flux Representations of Complex

Kinetics Networks. AICHE Journal. 58(2), 553, 2012.

4. Zhang, S., Broadbelt, L., Androulakis, I.P., Ierapetritou, M.G. Comparison of Biodiesel

Performance Based on HCCI Engine Simulation Using Detailed Mechanism with On-the-

fly Reduction. Energy and Fuels. 25(2), 976, 2012.

5. Orman, M.A., Mattick, J., Androulakis, I.P., Berthiaume,F., Ierapetritou, M.G.

Stoichiometry based steady-state hepatic flux analysis: Computational and experimental

aspects. Metabolites. 2(1), 268, 2012.

6. Boukouvala, F., Dubey, A.,Vanarase, A.,Muzzio F.,Ierapetritou, M.G. Computational

approaches for studying the granular dynamics of continuous blending processes,2-

Population balance and data-based methods. Macromolecular Materials and Eng. 297(1),

9, 2012.

7. Li, Z., and M.G. Ierapetritou Capacity expansion planning through augmented Lagrangian

optimization and scenario decomposition. AIChE Journal, 58, 871, 2012.

8. Orman, M.A.,Androulakis, I.P., Berthiaume,F., Ierapetritou, M.G. Metabolic network

analysis of perfused livers under fed and fasted states: Incorporating thermodynamic and

futile-cycle-associated regulatory constraints. Journal of Theoretical Biology. 293, 101,

2012.

9. Boukouvala, F., Ierapetritou, M.G. Feasibility analysis of black-box processes using an

adaptive sampling kriging-based method. Computers and Chemical Engineering. 36,358,

2012.

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10. Dubey, A.,Boukouvala, F.,Keyvan, G.,Hsia, R.,Saranteas, K.,Brone, D.,Misra,

T.,Ierapetritou, M.,Muzzio, F. Improvement of Tablet Coating Uniformity Using a

Quality by Design Approach. AAPS PharmSciTech, Available online, Doi:

10.1208/s12249-011-9723-xm 2012.

11. Orman, M.A., Berthiaume, F., Androulakis, I.P., Ierapetritou, M.G. Advanced

Stoichiometric Analysis of Metabolic Networks of Mammalian Systems. Critical Reviews

in Biomedical Engineering. 39(6), 511, 2011.

12. Ramachandran,R., Arjunan, J., Chaudhury, A., Ierapetritou, M.G. Model-Based control

loop performance assessment of a continuous direct compaction pharmaceutical process.

J. Pharm. Innov. 6, 249, 2011.

13. Nikolopoulou, A., Ierapetritou, M.G. Integration of operation planning and scheduling in

supply chain systems: a review. Chapter 1, In: Scheduling problems and solutions, Nova

Science Publishers, 2011.

14. Yang, Q.,Orman, M.A., Ierapetritou, M.G., Berthiaume,F., Androulakis I.P. Dynamics of

short-term gene expression profiling in liver following thermal injury. J. Surg. Res.,

Available online, doi:10.1016/j.jss.2011.09.052.

15. Orman, M.A.,Ierapetritou, M.G., Berthiaume,F., Androulakis I.P. The dynamics of the

early inflammatory response in double-hit burn and sepsis animal models. Cytokine.

56(2), 494, 2011.

16. Orman, M.A., Nguyen, T.T., Ierapetritou, M.G., Berthiaume,F., Androulakis I.P.

Comparison of the cytokine and chemokine dynamics of the early inflammatory response

in models of burn injury and infection. Cytokine. 55, 362, 2011.

17. Orman, M.A.,Ierapetritou, M.G.,Androulakis I.P., Berthiaume,F. Metabolic response of

perfused livers to various oxygenation conditions. Biotechnology and Bioengineering.

108(12), 2947, 2011.

18. Smith,B., Ierapetritou, M.G. Modeling and optimization of product design and portofolio

management interface. Computers and Chemical Engineering. 35, 2579, 2011.

19. He, K., I.P. Androulakis, M.G. Ierapetritou. Numerical Investigation of Homogeneous

Charge Compression Ignition (HCCI) Combustion with Detailed Chemical Kinetics

Using On-the-Fly Reduction. Energy and Fuels. 25(8), 3369, 2011.

20. Smith,B., Ierapetritou, M.G. Sensitivity-Based product portofolio and design integration.

Industrial Eng. & Chem. Research 50, 3919, 2011.

21. Dubey, A.,Sarkar, A., Ierapetritou, M.G.,Muzzio F.et al. Computational approaches for

studying the granular dynamics of continuous blending processes,1- Dem based methods.

Macromolecular Materials and Eng. 296, 290, 2011.

22. Yang, H., Ierapetritou, M.G., Roth C.M. Analysis of Amino Acid Supplementation

Effects on Hepatocyte Cultures Using Flux Balance Analysis. OMICS: A Journal of

Integrative Biology. 15, 449, 2011.

23. Ovacik, M.A.,Sen, B., Euling S.Y., Gaido, K.W., Ierapetritou, M.G., Androulakis

I.P.Pathway modeling of microarray data: A case study of pathway activity changes in the

testis following in utero exposure to dibutyl phthalate (DBP). Toxicology and Applied

Pharmacology, In Press, doi:10.1016/j.taap.2010.09.008

24. Orman, M.A., Berthiaume,F.,Androulakis I.P., Ierapetritou, M.G. Pathway analysis of

liver metabolism under stressed condition. Journal of Theoretical Biology 272, 131, 2011.

25. Shah, N., Li, Z., and M.G. Ierapetritou Petroleum refining operations: key issues,

advances and opportunities. Ind. Eng. Chem. Res. 50, 1161, 2011.

13

26. Gao Y.,Vanarase A.U., Muzzio F., Ierapetritou M.G. Characterizing continuous powder

mixing using residence time distribution. Chemical Engineering Science. 66, 417, 2011.

27. Saharidis, G., Androulakis, I., and Ierapetritou, M.G. Model Building Using Bi-level

Optimization. Journal of Global Optimization. 49, 49, 2011.

28. Shah,N.and M.G. Ierapetritou Short-term scheduling of a large-scale refinery operations:

incorporating logistics. AIChE Journal, 57(6), 1570, 2011.

29. Gao Y., Muzzio F., Ierapetritou M.G. Characterization of feeder effects on continuous

solid mixing using Fourier series analysis. AIChE Journal, 57(5), 1144, 2011.

30. Orman, M.A., Arai, K., Yarmush, M.L., Androulakis, I.P., Berthiaume,F., Ierapetritou,

M.G.Metabolic flux determination in perfused livers by mass balance analysis: Effect of

fasting. Biotechnology and Bioengineering, 107, 1097, 2010.

31. He, K., I.P. Androulakis, M.G. Ierapetritou. Incorporation of Detailed Chemical

Mechanisms in Reactive Flow Simulations Using Element-Flux Analysis. Ind. Eng.

Chem. Res. 49 10471, 2010.

32. Portillo, P.M., Vanarase A.U., Ingram A., Seville J.K., Ierapetritou, M.G., Muzzio, F.J.

Investigation of the effect of impeller rotation rate, powder flow rate, and cohesion on

powder flow behavior in a continuous blender using PEPT. Chemical Engineering

Science, 65, 5658, 2010.

33. Iyer, V.V., Ovacik, M.A., Androulakis, I.P., Roth, C.M., Ierapetritou,

M.G.Transcriptional and metabolic flux profiling of triadimefon effects on cultured

hepatocytes. Toxicology and Applied Pharmacology, 248, 165, 2010.

34. Boukouvala, F., Muzzio, F.J., and Ierapetritou, M.G. Design Space of pharmaceutical

processes using data-driven-based methods. Journal of Pharmaceutical Innovation, 5,

119, 2010.

35. Yang, H., Ierapetritou, M.G., Roth C.M. Effects of amino acid transport limitations on

cultured hepatocytes. Biophysical Chemistry, 152, 89, 2010.

36. Li, Z., and M.G. Ierapetritou Rolling horizon based planning and scheduling integration

with production capacity consideration. Chem. Eng. Science, 65, 5887, 2010.

37. Saharidis, G., and M.G. Ierapetritou. Improving benders decomposition using maximum

feasible subsystem (MFS) cut generation strategy. Comp. Chem. Eng., 34, 1237, 2010.

38. He, K., M.G. Ierapetritou, I.P. Androulakis Integration of on-the-fly kinetic reduction

with multidimensional CFD. AIChE J., 56 1305, 2010.

39. Iyer, V.V., Yang, H., Ierapetritou, M.G., Roth C.M. Effects of Glucose and Insulin Level

on HepG2-C3A Cell Metabolism. Biotechnology and Bioengineering, 107, 347, 2010.

40. Boukouvala, F., Muzzio, F.J., and Ierapetritou, M.G. Predictive Modeling of

Pharmaceutical Processes with Missing and Noisy Data. AIChE Journal, 56, 2860, 2010.

41. Smith, B., and M.G. Ierapetritou. Integrative Chemical Product Design Strategies:

Reflecting Industry Trends and Challenges. Comp. Chem. Eng. 34, 857, 2010.

42. Li, Z., and M.G. Ierapetritou Production planning and scheduling integration through

augmented Lagrangian optimization. Comp. Chem. Eng. 34, 996, 2010.

43. Saharidis, G. K. D., M. Minoux, M. G. Ierapetritou.Accelerating Bender's method using

covering cut bundle generation. Intl. Trans. in Op. Res., 17, 221, 2010.

44. Davis, E., and M.G. Ierapetritou. A Centroid-Based Sampling Strategy for Kriging Global

Modeling and Optimization. AIChE J. 56, 220, 2010.

14

45. Saharidis, G. K. D., M. M. Golias, M. Boile, S. Theofanis, M. G. Ierapetritou.The berth

scheduling problem with customer differentiation: a new methodological approach based

on hierarchical optimization. Int J Adv Manuf Technol, 46, 377, 2010.

46. He, K., I.P. Androulakis, and M.G. Ierapetritou. Multi-element Flux Analysis for the

Incorporation of Detailed Kinetic Mechanisms in Reactive Simulations. Energy Fuels, 24,

309, 2010.

47. He, K., I.P. Androulakis, and M.G. Ierapetritou. On-the-fly reduction of kinetic

mechanisms using element flux analysis. Chem. Eng. Sci., 65, 1173, 2010.

48. Ierapetritou M.G., P.G. Georgopoulos, C.M. Roth, I.P. Androulakis. Tissue-Level

Modeling of Xenobiotic Metabolism in Liver: An Emerging Tool for Enabling Clinical

Translational Research. Cts-Clinical and Translational Science, 2, 228, 2009.

49. Jia, Z., E.Davis, F. Muzzio, and M.G. Ierapetritou. Predictive Modeling for

Pharmaceutical Processes using Kriging and Response Surface. Jl. Pharm. Innov., 4, 174,

2009.

50. Saharidis, G., and M.G. Ierapetritou. Scheduling of Loading and Unloading of Crude oil

in a refinery with combine mixture preparation. Ind. Eng. Chem. Res., 48, 2624, 2009.

51. Yang, H., and M.G. Ierapetritou. A Rational Design Approach for Amino Acid

Supplementation in Hepatocyte Culture. Biotechnology and Bioengineering. 103, 1176,

2009.

52. Lima, F.V., Z. Jia, M.G. Ierapetritou and C. Georgakis Similarities and Differences

between the Concepts of Operability and Flexibility. AIChE J., 56, 702, 2009.

53. Golias, M.M., Saharidis, G.K., Boile, M., Theofanis, S., Ierapetritou, M.G. The berth

allocation problem: Optimizing vessel arrvial times. Journal of Maritime Economics and

Logistics. 11, 358, 2009.

54. Portillo, P.M., M.G. Ierapetritou and F.J. Muzzio Effects of rotation rate, mixing angle,

and cohesion in two continuous powder mixers A statistical approach. Powder

Technology. 194, 217, 2009.

55. Li, Z., and M.G. Ierapetritou Integrated planning and scheduling in a decomposition

framework. Chemical Engineering Science, 64, 3585, 2009.

56. Foteinou, P., E. Yang, G.K. Saharidis, M.G. Ierapetritou and I.P. Androulakis. A Mixed-

Integer Optimization Framework for the Synthesis and Analysis of Regulatory Networks.

Jl. Glob Optim. 43, 263, 2009.

57. Davis, E., and M.G. Ierapetritou. A Kriging Based Method for the Solution of Mixed-

Integer Nonlinear Programs Containing Black-Box Functions. Jl. Glob. Opt. 43, 191,

2009.

58. Ierapetritou, M.G. and Z. Jia. Short Term Scheduling Under Uncertainty: Sensitivity

Analysis. Encyclopedia of Optimization Second Edition, 3560-3567, C.A. Floudas and

P.M. Pardalos (eds), Springer, 2009.

59. Ierapetritou, M.G. and I. Banerjee. Shape Reconstruction Methods for Nonconvex

Feasibility Analysis Encyclopedia of Optimization Second Edition, 3491-3500, C.A.

Floudas and P.M. Pardalos (eds), Springer, 2009.

60. Ierapetritou, M.G. and Z. Jia. Gasoline Blending and Distribution Scheduling: An MILP

model. Encyclopedia of Optimization Second Edition, 1113-1127, C.A. Floudas and P.M.

Pardalos (eds), Springer, 2009.

15

61. Portillo P.M., Ierapetritou M.G., Tomassone M.S., Mc Dade C., Clancy D., Avontuur

P.C., and Muzzio F.J. Quality by Design Methodology for Development and Scale Up of

Batch Mixing Processes. Journal of Pharmaceutical Innovation. 3, 258, 2008.

62. Ierapetritou, M.G. and Z. Li. Modeling and Managing Uncertainty in Process Planning

and Scheduling. Springer volume in Optimization and Logistics Challenges in the

Enterprise. Kevin Furman and W. Art Chaovalitwongse (eds), Springer, 2008.

63. Portillo, P.M., M.G. Ierapetritou, and F.J. Muzzio Using Compartment Modeling to

Investigate Mixing Behavior of a Continuous Mixer. Jl. Ind. Pharm. 3, 161, 2008.

64. Euling, S.Y., Makris, S., Sen, B., White, L., Benson, R., Gaido, K.W., Kim, A.S., Hester,

S., Wilson, V.S., Keshava, C., Keshava, N., Foster, P.M., Androulakis, I.P., Ovacik, M.,

Ierapetritou, M.G., Gray, L.E., Thompson, C., and Chiu, W. An approach to using

genomics data in risk assessment: Dibutyl phthalate (DBP) case study. Birth Defects

Research Part a-Clinical and Molecular Teratology 82, 296, 2008.

65. Li, Z., and M.G. Ierapetritou. Reactive Scheduling Based On Parametric Solution. AIChE

J., 47, 2610, 2008.

66. Li, Z., and M.G. Ierapetritou. Robust optimization for process scheduling under

uncertainty. Ind. Eng.Chem. Res. 47, 4148, 2008.

67. He, K., M.G. Ierapetritou and I.P. Androulakis. A graph-based approach for developing

adaptive representations of complex reaction mechanisms. Comb. & Flame 155, 585,

2008.

68. Portillo, P.M., M.G. Ierapetritou, and F.J. Muzzio Characterization of Continuous

Convective Powder Mixing Processes. Powder Technology. 182, 368, 2008.

69. Li, Z. and M.G. Ierapetritou Process scheduling under uncertainty: Review and

challenges. Comp. Chem. Eng 32, 715, 2008.

70. Furman, K.C., Z. Jia, M.G. Ierapetritou A robust event-based continuous time formulation

for tank transfer scheduling. Ind. Eng. Chem. Res. 46, 9126, 2007.

71. Li, Z. and M.G. Ierapetritou Process scheduling under uncertainty using multiparametric

programming. AIChE Jl. 53, 3183, 2007.

72. Li, Z. and M.G. Ierapetritou A new methodology for the general multiparametric mixed-

integer linear programming (MILP) problems Ind. Eng. Chem. Res. 46, 5141, 2007.

73. Wu, D. and M.G. Ierapetritou Hierarchical approach for production planning and

scheduling under uncertainty. Chem. Eng. & Process. 46, 1129, 2007

74. Ierapetritou, M.G. and Z. Jia Short-term scheduling of chemical process including

uncertainty. Control Engineering Practice. 15, 1207, 2007.

75. Davis, E. and M.G. Ierapetritou A kriging method for the solution of nonlinear programs

with black-box functions. AIChE Jl. 53, 2001, 2007.

76. Portillo P.M., Muzzio F.J., Ierapetritou M.G. Hybrid DEM-compartment modeling

approach for granular mixing. AIChE Jl 53 (1): 119, 2007.

77. Jia, Z. and M.G. Ierapetritou. Generate Pareto Optimal Solutions of Scheduling Problems

using Normal Boundary Intersection Technique. Comp. Chem. Eng. 31, 268, 2007.

78. Davis, E., and M.G. Ierapetritou Adaptive Optimization of Noisy Black-Box Functions

Inherent in Microscopic Models. Comp. Chem. Eng., 31, 466, 2007.

79. Goyal, V., and M.G. Ierapetritou. Stochastic MINLP Optimization using Simplicial

Approximation. Comp. Chem. Eng., 31, 1081, 2007.

80. Portillo, P. F. Muzzio and M.G. Ierapetritou. Characterizing Powder Mixing Processes

utilizing Compartment Models. Int. Jl. Of Pharm. 320, 14, 2006.

16

81. Jia, Z. and M.G. Ierapetritou. Uncertainty Analysis on the RHS for MILP problems.

AIChE J., 52, 2486, 2006.

82. Wu, D., and M.G. Ierapetritou. Improved Lagrangean Decomposition Approach for MILP

Problems. Comp. Chem. Eng. 30, 778, 2006.

83. Banerjee, I., and M.G. Ierapetritou. An Adaptive Reduction Scheme to Model Reactive

Flow. Comb. Flame, 144, 219, 2006.

84. Bindal, A., M.G. Ierapetritou, S. Balakrishnan, A. Makeev, I. Kevrekidis and A. Armaou.

Equation-free, coarse-grained computational optimization using timesteppers. Chem. Eng.

Sci. 61, 279, 2006.

85. Sharma, N., M.G. Ierapetritou and M.L. Yarmush. Novel Quantitative Tools for

Engineering Analysis of Hepatocyte Cultures in Bioartificial Liver Systems.

Biotechnology and Bioengineering, 92(3), 321, 2005.

86. Balakrishnan S., Roy A., Ierapetritou M.G., Flach G.P. and Georgopoulos P.G. A

Comparative Assessment of Efficient Uncertainty Analysis Techniques for Environmental

Fate and Transport Models: Application to the FACT Model. Journal of Hydrology 307

(1-4): 204-218 JUN 9 2005.

87. Banerjee, I., and M.G. Ierapetritou. Feasibility evaluation of nonconvex systems using

shape reconstruction techniques. Ind. Eng. Chem. Res., 44, 3638, 2005.

88. Goyal, V. and M.G. Ierapetritou. Multiobjective Framework for Modular Design

Generation Incorporating Demand Uncertainty, Ind. Eng. Chem. Res., 44, 3594 2005.

89. Sirdeshpande, A.R., M.G. Ierapetritou, M.J. Andrecovich, J.P. Naumovitz. Process

synthesis optimization and flexibility evaluation of air separation cycles. AIChE J., 51,

1190, 2005.

90. Goyal, V. and M.G. Ierapetritou. Deterministic framework for robust modular design with

integrated-demand data analysis. Ind. Eng. Chem. Res. 43, 6813, 2004.

91. Wu, D., and M.G. Ierapetritou. Cyclic Short-Term Scheduling of Multiproduct Batch

Plants using Continuous Time Formulation. Comput. Chem, Eng. 28, 2271, 2004.

92. Jia, Z., and M.G. Ierapetritou. Efficient short-term scheduling of refinery operations based

on a continuous time formulation. Comput. Chem. Eng. 28, 1001, 2004.

93. Jia, Z., and M.G. Ierapetritou. Short-Term Scheduling under Uncertainty Using MILP

Sensitivity Analysis. Ind. & Eng. Chem. Res., 43, 3782, 2004.

94. Hauksdottir, A.S., U. Zuhlke, M.G. Ierapetritou and V. Goyal. The Solution of

Simultaneous Decoupling and Pole Placement Problem using Global Optimization.

Special Issue of Comp. Chem. Eng. The integration of Process Design and Control,

Panos Seferlis, Michael Georgiadis (Eds) Elsevier, 582, 2004.

95. Goyal, V. and M.G. Ierapetritou. Computational Studies using a Novel Simplicial-

approximation based Algorithm for MINLP Optimization. Comput. Chem. Engng. 28,

1771, 2004.

96. Banerjee, I., and M.G. Ierapetritou. Model Independent Parametric Decision Making.

Ann. Oper. Res., 132, 135, 2004.

97. Goyal, V. and M.G. Ierapetritou. MINLP Optimization Using Simplicial Approximation

Method for Classes of Nonconvex Problems. In Nonconvex Optimization and Its

Applications #74: Frontiers in Global Optimization, C.A. Floudas and P.M. Pardalos

(Eds), Springer, 2003, page 165.

98. Banerjee, I., and M.G. Ierapetritou. Development of an Adaptive Chemistry Model

Considering Micromixing Effects. Chem. Eng. Sci, 8, 4537, 2003.

17

99. Goyal, V. and M.G. Ierapetritou. Framework for Evaluating the Feasibility/Operability of

Nonconvex Processes. AIChE J, 49, 1233, 2003.

100. Jia, Z., and M.G. Ierapetritou. Mixed Integer Programming Model for Gasoline Blending

and Distribution Scheduling, Ind. Eng. & Chem. Res., 42, 825, 2003.

101. Bindal, A., M.G. Ierapetritou and J.Khinast. Adaptive Multiscale Solution of Dynamical

Systems in Chemical Processes Using Wavelets. Comp. Chem. Eng., 27, 131, 2003.

102. Wu, D., and M.G. Ierapetritou. Decomposition Approaches for the Efficient Solution of

Short-Term Scheduling Problem. Comp. Chem. Eng., 27, 1261, 2003.

103. Banerjee, I., and M.G. Ierapetritou. Process Synthesis under Parameter Variability.

Comput. Chem. Eng., 27, 1499, 2003.

104. Jia, Z., M.G. Ierapetritou and J. D. Kelly. Refinery Short-term Scheduling Using

Continuous Time Formulation Crude Oil Operations, Ind. Eng. & Chem. Res, 42, 3085,

2003.

105. Balakrishnan, S., A. Roy, M.G. Ierapetritou, G.P. Flach, and P. Georgopoulos.

Uncertainty Reduction and Characterization of Complex Environmental Fate and

Transport Models: An Empirical Bayesian Framework Incorporating the Stochastic

Response Surface Method. Water Resources Research, 39(12): 1350, 2003.

106. Goyal, V. and M.G. Ierapetritou. Integration of Data Analysis and Design Optimization

for the systematic Generation of Equipment Portfolio. Ind. & Eng. Chem. Res, 42, 5204,

2003.

107. Balakrishnan, S., P. Georgopoulos, I. Banerjee and M.G. Ierapetritou. Uncertainty

Considerations in the Complex Kinetic Mechanisms Reduction. AIChE J, 48, 2875, 2002.

108. Banerjee, I., and M.G. Ierapetritou. Design Optimization under Parameter Uncertainty for

General Black Box Models. Ind. & Eng. Chem. Res., 41, 6687, 2002.

109. Ierapetritou, M.G., D. Wu, J. Vin, P. Sweeney, M. Chigirinskiy. Cost Minimization in an

Energy Intensive Plant Using Mathematical Programming Approaches. Ind. & Eng.

Chem. Res, 41, 5262, 2002.

110. Goyal, V. and M.G. Ierapetritou. Determination of Operability Limits Using Simplicial

Approximation. AIChE J, 48, 2902, 2002.

111. Ierapetritou, M.G. and J.Khinast. A New Stability Analysis Approach for Chemical

Reactors Based on Iterative Sampling and Optimization. AIChE J., 48, 187, 2002.

112. Vin, J., and M.G. Ierapetritou. Robust Short-Term Scheduling of Multiproduct Batch

Plants under Demand Uncertainty. Ind. & Eng. Chem. Res, 40, 4543, 2001.

113. Ierapetritou M.G., and C.A. Floudas. Comments on "An improved RTN continuous-time

formulation for the short-term scheduling of multipurpose batch plants". Ind. & Eng.

Chem. Res, 40, 5040, 2001.

114. Sirdeshpande, A., M.G. Ierapetritou, and I.P. Androulakis. Design of Flexible Reduced

Kinetic Mechanisms. AIChE J., 47, 2461, 2001.

115. Floudas, C.A., Z. Gumus, and M.G. Ierapetritou Global Optimization for the Feasibility

Test and Flexibility Index Problems, Ind. & Eng. Chem. Res, 40, 4267, 2001.

116. Ierapetritou, M.G. A New Approach for Quantifying Process Feasibility: Convex and one

Dimensional Quasi-Convex Regions. AIChE J., 47, 1407, 2001.

117. Ierapetritou, M.G. Bilevel Optimization: Feasibility Test and Flexibility Index

Encyclopedia of Optimization, C.A. Floudas and P.M. Pardalos (eds), Kluwer Academic

Publisher, Printed in the Netherlands, 2001.

18

118. Ierapetritou, M.G. MINLP: Application in Facility Location-Allocation Encyclopedia of

Optimization, C.A. Floudas and P.M. Pardalos (eds), Kluwer Academic Publisher, Printed

in the Netherlands, 2001.

119. Ierapetritou, M.G. Single Facility Location: Multi-objective Rectilinear Distance Location

Encyclopedia of Optimization, C.A. Floudas and P.M. Pardalos (eds), Kluwer Academic

Publisher, Printed in the Netherlands, 2001.

120. Ierapetritou, M.G. Single Facility Location: Multi-objective Euclidean Distance Location

Encyclopedia of Optimization, C.A. Floudas and P.M. Pardalos (eds), Kluwer Academic

Publisher, Printed in the Netherlands, 2001.

121. Vin, J., and M.G. Ierapetritou. A New Approach for Efficient Rescheduling of

Multiproduct Batch Plants. Ind. & Eng. Chem. Res, 39, 4228, 2000.

122. Ierapetritou M.G., I.P. Androulakis, D.S. Monos and C.A. Floudas, Structure Prediction

of Binding Sites of MHC Class II Molecules based on the Crystal of HLA-DR1 and

Global Optimization, State of the Art in Global Optimization: Computational Methods

and Applications, Eds: C.A. Floudas and P.M. Pardalos, Kluwer, 2000.

123. Ierapetritou M.G., T.S. Hene and C.A. Floudas, Effective Continuous-Time Formulation

for Short-Term Scheduling: III Multiple Intermediate Due Dates Ind. & Eng. Chem, 38, 9,

3446, 1999.

124. Ierapetritou M.G., and C.A. Floudas and S. Vansantharajan and A.S. Gullick, A

Decomposition Based Approach for Optimal Location of Vertical Wells AIChE J., 45, 4,

844, 1999.

125. Ierapetritou M.G., and C.A. Floudas, Effective Continuous-Time Formulation for Short-

Term Scheduling: I. Multipurpose Batch Processes Ind. & Eng. Chem. Res., 37, 11, 4341,

1998.

126. Ierapetritou M.G., and C.A. Floudas, Effective Continuous-Time Formulation for Short-

Term Scheduling: II. Multipurpose/Multiproduct Continuous Processes Ind. & Eng.

Chem. Res., 37, 11, 4360, 1998.

127. Ierapetritou, M.G, and C.A. Floudas, Short-Term Scheduling: New Mathematical Models

vs Algorithmic Improvements. Comp. & Chem. Eng., 22, S419, 1998.

128. Klepeis, J.L., M.G. Ierapetritou, and C.A. Floudas, Protein Folding and Peptide Docking:

A Molecular Modeling and Global Optimization Approach. Comp. & Chem. Eng., 22, S3,

1998

129. Klepeis, J.L., I.P. Androulakis, M.G. Ierapetritou, and C.A. Floudas, Predicting Solvated

Peptide Conformations via Global Minimization of Energetic atom-to-atom Interactions.

Comp. & Chem. Eng., 22, 765, 1998

130. Androulakis I.P., N.N. Nayak, M.G. Ierapetritou, D.S. Monos and C.A. Floudas,

Identification of Peptide Binding Specificity for Pocket 1 of HLA-DR1 Based on Global

Minimization of Energy Interactions. Proteins: Structure, Function and Genetics, 29, 87,

1997.

131. Epperly T., M.G. Ierapetritou and E.N. Pistikopoulos, On the global and efficient solution

of stochastic batch plant design problems Comp. & Chem. Eng., 21, 1411, 1997.

132. Ierapetritou, M.G., E.N. Pistikopoulos and C. A. Floudas, Operational Planning Under

Uncertainty. Comp. & Chem. Eng., 20, S1209, 1996.

133. Ierapetritou, M.G. and E. N. Pistikopoulos, Batch Plant Design and Operations under

Uncertainty Ind. & Eng. Chem. Res., 35, 772, 1996.

19

134. Ierapetritou, M.G., J. Acevedo and E.N. Pistikopoulos, An Optimization Approach for

Process Engineering Problems under Uncertainty. Comp. & Chem. Eng., 20, 703, 1996.

135. Pistikopoulos, E.M, T.V. Thomaidis, M. G. Ierapetritou and A. Melin, Flexibility,

Reliability and Maintenance considerations in Batch Plant Design Comp. & Chem. Eng.,

20, S1209, 1996.

136. Ierapetritou, M.G. and E. N. Pistikopoulos, Global Optimization for Stochastic Planning

Scheduling and Design Problems Global Optimization in Engineering Design,

I.E.Grossmann (ed), Kluwer Academic Publisher, Printed in the Netherlands, 231-287,

1996.

137. Visweswaran V., Floudas C.A., Ierapetritou, M.G. and Pistikopoulos E.N., A

Decomposition Based Global Optimization Approach for Bi-Level Convex Programming

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